RU2365373C2 - Применение ингибитора тирозинкиназы для лечения диабета - Google Patents

Применение ингибитора тирозинкиназы для лечения диабета Download PDF

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Publication number: RU2365373C2
Authority: RU; Russia
Prior art keywords: diabetes; abl; compound; cells; type
Prior art date: 2003-05-27

Application number

RU2005140516/15A

Other languages

English (en)

Russian (ru)

Other versions

RU2005140516A (ru

Inventor

Роберт Пер Хэгерквист (Se)

Роберт Пер Хэгерквист

Нильс Ричард УЭЛШ (SE)

Нильс Ричард Уэлш

Original Assignee

Роберт Пер Хэгерквист

Нильс Ричард Уэлш

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-05-27

Filing date

2004-05-26

Publication date

2009-08-27

2003-05-27 Priority claimed from GB0312086A external-priority patent/GB0312086D0/en

2004-02-06 Priority claimed from GB0402682A external-priority patent/GB0402682D0/en

2004-05-26 Application filed by Роберт Пер Хэгерквист, Нильс Ричард Уэлш filed Critical Роберт Пер Хэгерквист

2007-07-10 Publication of RU2005140516A publication Critical patent/RU2005140516A/ru

2009-08-27 Application granted granted Critical

2009-08-27 Publication of RU2365373C2 publication Critical patent/RU2365373C2/ru

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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
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General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
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Obesity (AREA)
Hematology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
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Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

RU2005140516/15A 2003-05-27 2004-05-26 Применение ингибитора тирозинкиназы для лечения диабета RU2365373C2 (ru)

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GB0312086.2		2003-05-27
GB0312086A GB0312086D0 (en)	2003-05-27	2003-05-27	Organic compounds
GB0402682.9		2004-02-06
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US (1)	US7875616B2 (pt)
EP (1)	EP1631291B1 (pt)
JP (1)	JP4776537B2 (pt)
KR (1)	KR101102229B1 (pt)
AT (1)	ATE439133T1 (pt)
BR (1)	BRPI0410704A (pt)
CA (1)	CA2526594C (pt)
DE (1)	DE602004022540D1 (pt)
DK (1)	DK1631291T3 (pt)
ES (1)	ES2331800T3 (pt)
IL (1)	IL171927A (pt)
IS (1)	IS2712B (pt)
MA (1)	MA27812A1 (pt)
MX (1)	MXPA05012739A (pt)
NO (1)	NO331715B1 (pt)
NZ (1)	NZ543709A (pt)
PL (1)	PL1631291T3 (pt)
PT (1)	PT1631291E (pt)
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JPWO2008001885A1 (ja) *	2006-06-30	2009-11-26	協和発酵キリン株式会社	Ａｂｌキナーゼ阻害剤
US20140221389A1 (en) *	2011-09-15	2014-08-07	Novartis Ag	Use of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinolin-2-one in the treatment of cancer in moderate hepatic impaired patients

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Publication number	Publication date
NZ543709A (en)	2009-04-30
JP4776537B2 (ja)	2011-09-21
BRPI0410704A (pt)	2006-06-13
EP1631291B1 (en)	2009-08-12
PT1631291E (pt)	2009-10-28
AU2004243491A1 (en)	2004-12-09
DK1631291T3 (da)	2009-11-02
CA2526594C (en)	2011-11-08
IL171927A0 (en)	2006-04-10
WO2004105763A2 (en)	2004-12-09
PL1631291T3 (pl)	2010-04-30
US7875616B2 (en)	2011-01-25
JP2006528225A (ja)	2006-12-14
DE602004022540D1 (de)	2009-09-24
ATE439133T1 (de)	2009-08-15
IS2712B (is)	2011-01-15
IS8139A (is)	2005-11-22
EP1631291A2 (en)	2006-03-08
ES2331800T3 (es)	2010-01-15
RU2005140516A (ru)	2007-07-10
HK1087638A1 (en)	2006-10-20
KR20060021865A (ko)	2006-03-08
US20070072932A1 (en)	2007-03-29
KR101102229B1 (ko)	2012-01-05
MA27812A1 (fr)	2006-03-01
CA2526594A1 (en)	2004-12-09
IL171927A (en)	2011-10-31
NO331715B1 (no)	2012-03-05
MXPA05012739A (es)	2006-05-17
NO20056188L (no)	2005-12-23
WO2004105763A3 (en)	2005-06-02

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2016-02-10	MM4A	The patent is invalid due to non-payment of fees	Effective date: 20150527

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