SE0201701D0 - Treatment of epithelial tumors and infections - Google Patents
Treatment of epithelial tumors and infectionsInfo
- Publication number
- SE0201701D0 SE0201701D0 SE0201701A SE0201701A SE0201701D0 SE 0201701 D0 SE0201701 D0 SE 0201701D0 SE 0201701 A SE0201701 A SE 0201701A SE 0201701 A SE0201701 A SE 0201701A SE 0201701 D0 SE0201701 D0 SE 0201701D0
- Authority
- SE
- Sweden
- Prior art keywords
- treatment
- specific
- cell
- protein
- subunit
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 102000009016 Cholera Toxin Human genes 0.000 abstract 4
- 108010049048 Cholera Toxin Proteins 0.000 abstract 4
- 210000004027 cell Anatomy 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 230000002519 immonomodulatory effect Effects 0.000 abstract 2
- 238000009169 immunotherapy Methods 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- IVOMOUWHDPKRLL-KQYNXXCUSA-N Cyclic adenosine monophosphate Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=CN=C2N)=C2N=C1 IVOMOUWHDPKRLL-KQYNXXCUSA-N 0.000 abstract 1
- 101710146739 Enterotoxin Proteins 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 206010052779 Transplant rejections Diseases 0.000 abstract 1
- IVOMOUWHDPKRLL-UHFFFAOYSA-N UNPD107823 Natural products O1C2COP(O)(=O)OC2C(O)C1N1C(N=CN=C2N)=C2N=C1 IVOMOUWHDPKRLL-UHFFFAOYSA-N 0.000 abstract 1
- 238000009825 accumulation Methods 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 210000000612 antigen-presenting cell Anatomy 0.000 abstract 1
- 230000001588 bifunctional effect Effects 0.000 abstract 1
- 229940095074 cyclic amp Drugs 0.000 abstract 1
- 239000000147 enterotoxin Substances 0.000 abstract 1
- 231100000655 enterotoxin Toxicity 0.000 abstract 1
- QPJBWNIQKHGLAU-IQZHVAEDSA-N ganglioside GM1 Chemical compound O[C@@H]1[C@@H](O)[C@H](OC[C@H](NC(=O)CCCCCCCCCCCCCCCCC)[C@H](O)\C=C\CCCCCCCCCCCCC)O[C@H](CO)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@]2(O[C@H]([C@H](NC(C)=O)[C@@H](O)C2)[C@H](O)[C@H](O)CO)C(O)=O)[C@@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O3)O)[C@@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](CO)O1 QPJBWNIQKHGLAU-IQZHVAEDSA-N 0.000 abstract 1
- 230000003259 immunoinhibitory effect Effects 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 150000004713 phosphodiesters Chemical group 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0201701A SE0201701D0 (sv) | 2002-06-05 | 2002-06-05 | Treatment of epithelial tumors and infections |
| JP2004510827A JP4937511B2 (ja) | 2002-06-05 | 2003-06-05 | 免疫系を調節するための二官能性組成物およびその使用 |
| PCT/SE2003/000935 WO2003103708A1 (en) | 2002-06-05 | 2003-06-05 | BIOFUNCTIONAL CpG OR OLIGO-/POLYNUCLEOTIDE AND TOXIN OR ENTEROTOXIN CONTAINING COMPOSITION |
| AT03730976T ATE418343T1 (de) | 2002-06-05 | 2003-06-05 | Biofunktionales cpg oder oligo-/polynucleotid und toxin oder enterotoxin enthaltende zusammensetzung |
| EP03730976A EP1549340B1 (en) | 2002-06-05 | 2003-06-05 | Biofunctional cpg or oligo-/polynucleotide and toxin or enterotoxin containing composition |
| CA2488366A CA2488366C (en) | 2002-06-05 | 2003-06-05 | Biofunctional cpg or oligo-/polynucleotide and toxin or enterotoxin containing composition |
| US10/515,344 US20100330101A1 (en) | 2002-06-05 | 2003-06-05 | BIFUNCTIONAL CpG OR OLIGO-/POLYNUCLEOTIDE AND TOXIN OR ENTEROTOXIN CONTAINING COMPOSITION |
| DE60325492T DE60325492D1 (de) | 2002-06-05 | 2003-06-05 | BIOFUNKTIONALES CpG ODER OLIGO-/POLYNUCLEOTID UND TOXIN ODER ENTEROTOXIN ENTHALTENDE ZUSAMMENSETZUNG |
| KR1020047019864A KR101043341B1 (ko) | 2002-06-05 | 2003-06-05 | 생체 관능성 씨피지 또는 올리고-/폴리뉴클레오티드 및독소 또는 장독소 함유 조성물 |
| CN038186233A CN1674935B (zh) | 2002-06-05 | 2003-06-05 | 含有CpG或寡/多核苷酸以及毒素或肠毒素的双功能组合物 |
| AU2003241251A AU2003241251B2 (en) | 2002-06-05 | 2003-06-05 | Biofunctional CpG or oligo-/polynucleotide and toxin or enterotoxin containing composition |
| KR1020117007337A KR20110042129A (ko) | 2002-06-05 | 2003-06-05 | 생체 관능성 씨피지 또는 올리고-/폴리뉴클레오티드 및 독소 또는 장독소 함유 조성물 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0201701A SE0201701D0 (sv) | 2002-06-05 | 2002-06-05 | Treatment of epithelial tumors and infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE0201701D0 true SE0201701D0 (sv) | 2002-06-05 |
Family
ID=20288076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0201701A SE0201701D0 (sv) | 2002-06-05 | 2002-06-05 | Treatment of epithelial tumors and infections |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20100330101A1 (sv) |
| EP (1) | EP1549340B1 (sv) |
| JP (1) | JP4937511B2 (sv) |
| KR (2) | KR20110042129A (sv) |
| CN (1) | CN1674935B (sv) |
| AT (1) | ATE418343T1 (sv) |
| AU (1) | AU2003241251B2 (sv) |
| CA (1) | CA2488366C (sv) |
| DE (1) | DE60325492D1 (sv) |
| SE (1) | SE0201701D0 (sv) |
| WO (1) | WO2003103708A1 (sv) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8158768B2 (en) | 2002-12-23 | 2012-04-17 | Dynavax Technologies Corporation | Immunostimulatory sequence oligonucleotides and methods of using the same |
| PL1794174T3 (pl) | 2004-09-01 | 2012-11-30 | Dynavax Tech Corp | Sposoby i kompozycje do hamowania wrodzonych odpowiedzi immunologicznych i autoodporności |
| AU2005316503A1 (en) * | 2004-12-17 | 2006-06-22 | Dynavax Technologies Corporation | Methods and compositions for induction or promotion of immune tolerance |
| ES2544877T3 (es) * | 2005-10-12 | 2015-09-04 | Idera Pharmaceuticals | Compuestos oligonucleótidos inmuno reguladores (IRO) para modular la respuesta inmune basada en receptor semejante a Toll |
| US8399423B2 (en) | 2005-10-12 | 2013-03-19 | Idera Pharmaceuticals, Inc. | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
| US8383598B2 (en) | 2005-10-12 | 2013-02-26 | Idera Pharmaceuticals, Inc. | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
| US8426375B2 (en) | 2005-10-12 | 2013-04-23 | Idera Pharmaceuticals, Inc. | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
| US20100144845A1 (en) * | 2006-08-04 | 2010-06-10 | Massachusetts Institute Of Technology | Oligonucleotide systems for targeted intracellular delivery |
| US8377898B2 (en) | 2006-10-12 | 2013-02-19 | Idera Pharmaceuticals, Inc. | Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response |
| EP2209896B1 (en) | 2007-10-26 | 2017-03-01 | Dynavax Technologies Corporation | Methods and compositions for inhibition of immune responses and autoimmunity |
| ES2569907T3 (es) | 2008-06-27 | 2016-05-13 | Zoetis Services Llc | Composiciones adyuvantes novedosas |
| EP3087988A3 (en) | 2008-10-06 | 2017-03-01 | Idera Pharmaceuticals, Inc. | Use of inhibitors of toll-like receptors in the prevention and treatment of hypercholesterolemia and hyperlipidemia and diseases related thereto |
| US8241608B2 (en) * | 2010-03-23 | 2012-08-14 | Development Center For Biotechnology | Treating allergy with detoxified E. coli heat-labile enterotoxin |
| CN103153346A (zh) | 2010-06-16 | 2013-06-12 | 戴纳瓦克斯技术公司 | 使用tlr7和/或tlr9抑制剂的治疗方法 |
| AR091569A1 (es) * | 2012-06-28 | 2015-02-11 | Intervet Int Bv | Receptores de tipo toll |
| KR20200039025A (ko) | 2013-09-19 | 2020-04-14 | 조에티스 서비시즈 엘엘씨 | 유성 아쥬반트 |
| CN104004698A (zh) * | 2014-06-11 | 2014-08-27 | 河北科星药业有限公司 | 大肠埃希氏菌Escherichia coli及其制备方法 |
| MX391930B (es) | 2015-01-16 | 2025-03-21 | Zoetis Services Llc | Vacuna contra la fiebre aftosa. |
| CN117462701B (zh) * | 2023-10-31 | 2026-04-07 | 暨南大学 | 一种靶向肝脏的变形红细胞制剂及其制备方法与应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4587044A (en) * | 1983-09-01 | 1986-05-06 | The Johns Hopkins University | Linkage of proteins to nucleic acids |
| GB9317380D0 (en) * | 1993-08-20 | 1993-10-06 | Therexsys Ltd | Transfection process |
| AU713040B2 (en) * | 1994-07-15 | 1999-11-18 | University Of Iowa Research Foundation, The | Immunomodulatory oligonucleotides |
| ES2264136T3 (es) * | 1995-02-21 | 2006-12-16 | Cantab Pharmaceuticals Research Limited | Preparaciones virales, vectores, inmunogenos y sus vacunas. |
| US6261787B1 (en) * | 1996-06-03 | 2001-07-17 | Case Western Reserve University | Bifunctional molecules for delivery of therapeutics |
| US6589940B1 (en) * | 1997-06-06 | 2003-07-08 | Dynavax Technologies Corporation | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof |
| BR9909915A (pt) * | 1998-04-09 | 2000-12-26 | Smithkline Beecham Biolog | Composições adjuvantes |
| DK1077722T3 (da) * | 1998-05-22 | 2006-11-27 | Ottawa Health Research Inst | Fremgangsmåder og produkter til induktion af mukosaimmunitet |
| WO2001083528A2 (en) * | 2000-05-01 | 2001-11-08 | Powderject Vaccines, Inc. | Nucleic acid immunization |
| WO2002011761A2 (en) * | 2000-08-10 | 2002-02-14 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Vaccine against rsv |
-
2002
- 2002-06-05 SE SE0201701A patent/SE0201701D0/sv unknown
-
2003
- 2003-06-05 KR KR1020117007337A patent/KR20110042129A/ko not_active Ceased
- 2003-06-05 EP EP03730976A patent/EP1549340B1/en not_active Expired - Lifetime
- 2003-06-05 AT AT03730976T patent/ATE418343T1/de active
- 2003-06-05 DE DE60325492T patent/DE60325492D1/de not_active Expired - Lifetime
- 2003-06-05 US US10/515,344 patent/US20100330101A1/en not_active Abandoned
- 2003-06-05 WO PCT/SE2003/000935 patent/WO2003103708A1/en not_active Ceased
- 2003-06-05 CN CN038186233A patent/CN1674935B/zh not_active Expired - Fee Related
- 2003-06-05 KR KR1020047019864A patent/KR101043341B1/ko not_active Expired - Fee Related
- 2003-06-05 AU AU2003241251A patent/AU2003241251B2/en not_active Ceased
- 2003-06-05 CA CA2488366A patent/CA2488366C/en not_active Expired - Fee Related
- 2003-06-05 JP JP2004510827A patent/JP4937511B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050027218A (ko) | 2005-03-18 |
| US20100330101A1 (en) | 2010-12-30 |
| JP4937511B2 (ja) | 2012-05-23 |
| DE60325492D1 (de) | 2009-02-05 |
| JP2005538957A (ja) | 2005-12-22 |
| CA2488366C (en) | 2012-07-17 |
| KR101043341B1 (ko) | 2011-06-21 |
| CN1674935B (zh) | 2011-03-02 |
| ATE418343T1 (de) | 2009-01-15 |
| WO2003103708A1 (en) | 2003-12-18 |
| EP1549340A1 (en) | 2005-07-06 |
| CA2488366A1 (en) | 2003-12-18 |
| KR20110042129A (ko) | 2011-04-22 |
| EP1549340B1 (en) | 2008-12-24 |
| AU2003241251A1 (en) | 2003-12-22 |
| CN1674935A (zh) | 2005-09-28 |
| AU2003241251B2 (en) | 2008-07-24 |
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