SE0300207D0 - New use and composition - Google Patents

New use and composition

Info

Publication number
SE0300207D0
SE0300207D0 SE0300207A SE0300207A SE0300207D0 SE 0300207 D0 SE0300207 D0 SE 0300207D0 SE 0300207 A SE0300207 A SE 0300207A SE 0300207 A SE0300207 A SE 0300207A SE 0300207 D0 SE0300207 D0 SE 0300207D0
Authority
SE
Sweden
Prior art keywords
composition
new use
digalactosyldiacylglycerol
wounds
bilayer
Prior art date
Application number
SE0300207A
Other languages
English (en)
Swedish (sv)
Inventor
Mona Staahle-Baeckdahl
Johan Heilborn
Conny Bogentoft
Anders Carlsson
Original Assignee
Karolinska Innovations Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20290232&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE0300207(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Karolinska Innovations Ab filed Critical Karolinska Innovations Ab
Priority to SE0300207A priority Critical patent/SE0300207D0/xx
Publication of SE0300207D0 publication Critical patent/SE0300207D0/xx
Priority to ES04705973.8T priority patent/ES2467090T3/es
Priority to DK04705973.8T priority patent/DK1589987T3/da
Priority to CN201510400952.7A priority patent/CN105079784B/zh
Priority to US10/543,659 priority patent/US7452864B2/en
Priority to PCT/SE2004/000111 priority patent/WO2004067025A1/fr
Priority to CN2004800032098A priority patent/CN1744913B/zh
Priority to CN201010150582A priority patent/CN101838326A/zh
Priority to JP2006502781A priority patent/JP4750690B2/ja
Priority to SI200432154T priority patent/SI1589987T1/sl
Priority to PT47059738T priority patent/PT1589987E/pt
Priority to CA2513598A priority patent/CA2513598C/fr
Priority to EP04705973.8A priority patent/EP1589987B1/fr
Priority to ZA200505830A priority patent/ZA200505830B/en
Priority to US12/232,215 priority patent/US8012933B2/en
Priority to US13/193,131 priority patent/US8506994B2/en
Priority to US13/938,120 priority patent/US8936807B2/en
Priority to CY20141100342T priority patent/CY1115142T1/el
Priority to US14/567,267 priority patent/US9125875B2/en
Priority to HK16105830.5A priority patent/HK1217661B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629—Keratinocytes; Whole skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/36—Lipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Dispersion Chemistry (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
SE0300207A 2003-01-29 2003-01-29 New use and composition SE0300207D0 (sv)

Priority Applications (20)

Application Number Priority Date Filing Date Title
SE0300207A SE0300207D0 (sv) 2003-01-29 2003-01-29 New use and composition
CA2513598A CA2513598C (fr) 2003-01-29 2004-01-28 Utilisation de la cathelicidine ll-37 et de derives associes pour une cicatrisation de plaie
EP04705973.8A EP1589987B1 (fr) 2003-01-29 2004-01-28 Utilisation de peptides derivés de la cathelicidine ll-37 pour le traitement des plaies chroniques
CN201010150582A CN101838326A (zh) 2003-01-29 2004-01-28 Cathelicidin ll-37及其衍生物在伤口愈合中的用途
PT47059738T PT1589987E (pt) 2003-01-29 2004-01-28 Uso do péptido ll-37 de catelicidina e seus derivados no tratmento de feridas crónicas
CN201510400952.7A CN105079784B (zh) 2003-01-29 2004-01-28 Cathelicidin ll-37及其衍生物在伤口愈合中的用途
US10/543,659 US7452864B2 (en) 2003-01-29 2004-01-28 Use of the cathelicidin LL-37 and derivatives thereof for wound healing
PCT/SE2004/000111 WO2004067025A1 (fr) 2003-01-29 2004-01-28 Utilisation de la cathelicidine ll-37 et de derives associes pour une cicatrisation de plaie
CN2004800032098A CN1744913B (zh) 2003-01-29 2004-01-28 Cathelicidin ll-37及其衍生物在伤口愈合中的用途
ES04705973.8T ES2467090T3 (es) 2003-01-29 2004-01-28 Uso de péptidos derivados de la catelicidina LL-37 para usar en el tratamiento de heridas crónicas
JP2006502781A JP4750690B2 (ja) 2003-01-29 2004-01-28 創傷治癒のための、カテリシジンｌｌ−３７、および、それらの誘導体の使用
SI200432154T SI1589987T1 (sl) 2003-01-29 2004-01-28 Uporaba katelicidin ll-37 peptidnih derivatov za uporabo pri zdravljenju kroniäśnih ran
DK04705973.8T DK1589987T3 (da) 2003-01-29 2004-01-28 Anvendelse af cathelicidin ll-37 peptid-derivativer til behandling af kroniske sår
ZA200505830A ZA200505830B (en) 2003-01-29 2005-07-20 Use of the cathelicidin LL-37 and derivatives thereof for wound healing
US12/232,215 US8012933B2 (en) 2003-01-29 2008-09-12 Use of the cathelicidin LL-37 and derivatives therof for wound healing
US13/193,131 US8506994B2 (en) 2003-01-29 2011-07-28 Use of the cathelicidin LL-37 and derivatives thereof for wound healing
US13/938,120 US8936807B2 (en) 2003-01-29 2013-07-09 Use of the cathelicidin LL-37 and derivatives thereof for wound healing
CY20141100342T CY1115142T1 (el) 2003-01-29 2014-05-15 Χρηση πεπτιδιων παραγωγων της καθελισιδινης ll-37 για τη θεραπεια χρονιων πληγων
US14/567,267 US9125875B2 (en) 2003-01-29 2014-12-11 Use of the cathelicidin LL-37 and derivatives thereof for wound healing
HK16105830.5A HK1217661B (en) 2003-01-29 2016-05-23 Use of the cathelicidin ll-37 and derivatives thereof for wound healing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0300207A SE0300207D0 (sv) 2003-01-29 2003-01-29 New use and composition

Publications (1)

Publication Number Publication Date
SE0300207D0 true SE0300207D0 (sv) 2003-01-29

Family

ID=20290232

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0300207A SE0300207D0 (sv) 2003-01-29 2003-01-29 New use and composition

Country Status (13)

Country Link
US (5) US7452864B2 (fr)
EP (1) EP1589987B1 (fr)
JP (1) JP4750690B2 (fr)
CN (3) CN1744913B (fr)
CA (1) CA2513598C (fr)
CY (1) CY1115142T1 (fr)
DK (1) DK1589987T3 (fr)
ES (1) ES2467090T3 (fr)
PT (1) PT1589987E (fr)
SE (1) SE0300207D0 (fr)
SI (1) SI1589987T1 (fr)
WO (1) WO2004067025A1 (fr)
ZA (1) ZA200505830B (fr)

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US20060258562A1 (en) * 2000-07-31 2006-11-16 Healor Ltd. Methods and pharmaceutical compositions for healing wounds
SE0300207D0 (sv) * 2003-01-29 2003-01-29 Karolinska Innovations Ab New use and composition
WO2004098536A2 (fr) * 2003-03-06 2004-11-18 The Regents Of The University Of California Activite antivirale de peptides cathelicidiniques
CA2534349C (fr) * 2003-08-01 2012-04-10 Stratatech Corporation Equivalents de peau humaine exprimant des polypeptides exogenes
WO2005013885A2 (fr) 2003-08-07 2005-02-17 Healor Ltd. Compositions pharmaceutiques et methodes permettant d'accelerer la cicatrisation de plaies
US7776823B2 (en) * 2003-10-21 2010-08-17 The Regents Of The University Of California Human cathelicidin antimicrobial peptides
SE0401942D0 (sv) * 2004-07-28 2004-07-28 Lipopeptide Ab New antimicrobial peptide complexes
CN101142233A (zh) * 2004-12-22 2008-03-12 利波佩普蒂德有限公司 抑制cathelin样蛋白hCAP18/LL-17的试剂
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US9044438B2 (en) 2005-06-17 2015-06-02 Yitzchak Hillman Disease treatment via antimicrobial peptides or their inhibitors
EP2452686A3 (fr) 2005-08-29 2012-09-05 HealOr Ltd. Procédés et compositions pour la prévention et le traitement du diabète et du vieillissement de la peau
JP2009541287A (ja) * 2006-06-20 2009-11-26 リポペプチド・アクチエボラーグ 抗癌剤としてのカテリシジン抗菌タンパク質（ｈＣＡＰ１８）の使用
WO2008073174A2 (fr) * 2006-09-08 2008-06-19 The Regents Of The University Of California Thérapie antimicrobienne
EP2069377A4 (fr) * 2006-09-27 2009-11-11 Univ California Procédés et compositions pour le traitement de maladies et de troubles de la peau
WO2008103751A2 (fr) * 2007-02-20 2008-08-28 The Regents Of The University Of California Thérapies et compositions antimicrobiennes et anti-inflammatoires
CA2691645A1 (fr) * 2007-06-25 2008-12-31 Lipopeptide Ab Nouveaux produits medicaux
EP2200628A2 (fr) * 2007-07-15 2010-06-30 Yitzchak Hillman Traitement de maladie par des peptides antimicrobien ou leurs inhibiteurs
CN102755649A (zh) * 2007-07-30 2012-10-31 希尔洛有限公司 药物组合物及相关方法
CN102459571B (zh) * 2009-06-04 2014-01-08 香港中文大学 抗炎细菌
AU2010306940A1 (en) 2009-10-12 2012-06-07 Smith, Larry Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro
WO2011056116A1 (fr) * 2009-11-03 2011-05-12 Lipidor Ab Composition pour favoriser la cicatrisation d'une plaie
US10279007B2 (en) 2010-11-15 2019-05-07 Oxygenetix Institute, Inc. Topical treatment method for healing wounds, disinfecting, covering and concealing the wound until healing occurs
WO2012150890A1 (fr) * 2011-05-02 2012-11-08 Lipidor Ab Composition antibactérienne
DK2827907T3 (da) * 2012-03-20 2019-06-11 Helix Biomedix Inc Korte antimikrobielle lipopeptider
WO2014004719A2 (fr) 2012-06-26 2014-01-03 Worcester Polytechnic Institute Echafaudage de matrice avec activité antimicrobienne
EP2821077A1 (fr) * 2013-07-04 2015-01-07 Praxis Biopharma Research Institute Nanoparticules lipidiques pour la cicatrisation des plaies
CN104513293A (zh) * 2013-09-26 2015-04-15 深圳信立泰药业股份有限公司 一种多肽疫苗的盐及其制备方法和含有该盐的药物制品
WO2015075406A1 (fr) 2013-11-19 2015-05-28 Lipopeptide Ab Nouveau traitement d'ulcères chroniques
CN103920137B (zh) * 2014-04-28 2016-03-30 中国药科大学 一种具有抗耐药性革兰阳性细菌作用的药物组合物
WO2015183683A2 (fr) * 2014-05-27 2015-12-03 Indiana University Research And Technology Corporation Antagoniste peptidique de ll -37
CN104984321A (zh) * 2015-07-24 2015-10-21 中国药科大学 人源抗菌肽ll-37在制备治疗或预防血栓性疾病药物中的应用
CN105859867A (zh) * 2016-05-30 2016-08-17 黄石市中心医院 一种人源抗菌肽ll-37突变体及其应用
CN106519042A (zh) * 2016-12-29 2017-03-22 陕西慧康生物科技有限责任公司 人源胶原蛋白与抗菌肽的融合蛋白及其制备方法与编码基因
US20190300575A1 (en) 2018-03-29 2019-10-03 Deetex, LLC Lytic peptide biosensor and methods of making and using the same
CN108659102B (zh) * 2018-04-25 2021-08-17 南方医科大学 具有抗菌及抗炎活性的多肽化合物
ES2799098B2 (es) 2019-06-10 2021-12-10 Univ Madrid Carlos Iii Aptameros agonistas del receptor fpr2 y usos de los mismos
KR102475936B1 (ko) * 2020-10-15 2022-12-09 코스맥스 주식회사 펩타이드 ll-37을 발현하는 효모를 포함하는 화장료 조성물
PL443243A1 (pl) * 2022-12-22 2024-06-24 Uniwersytet Warszawski Nowe peptydy antydrobnoustrojowe
CN118895244B (zh) * 2024-07-23 2025-06-20 浙江自贸区中航生物科技有限责任公司 一种提高nk细胞杀伤活性的多肽及其应用
CN120789277A (zh) * 2025-09-18 2025-10-17 山东大学 一种基于(1,3)-β-D-葡聚糖合成酶抑制剂的抗真菌药物组合物

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US6835713B2 (en) * 2001-02-16 2004-12-28 University Of Pittsburgh Virus derived antimicrobial peptides
US20030022829A1 (en) * 2001-03-30 2003-01-30 Wendy Maury Novel antiviral activities primate theta defensins and mammalian cathelicidins
WO2002095076A2 (fr) * 2001-05-23 2002-11-28 Kabushiki Kaisha Toyota Chuo Kenkyusho Polypeptides modifies presentant une resistance a la protease et/ou une sensibilite a la protease
EP1358888A1 (fr) 2002-02-28 2003-11-05 Robert Bals L'Antibiotique peptidique humain LL-37/hCAP-18 est un inducteur de l'angiogénèse
GB0223655D0 (en) * 2002-10-10 2002-11-20 Mabtech Ab Method of diagnosis
NZ540506A (en) 2002-12-19 2008-09-26 Yitzchak Hillman Disease treatment via antimicrobial peptide inhibitors
SE0300207D0 (sv) 2003-01-29 2003-01-29 Karolinska Innovations Ab New use and composition

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US20110293707A1 (en) 2011-12-01
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US8936807B2 (en) 2015-01-20
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EP1589987A1 (fr) 2005-11-02
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US8506994B2 (en) 2013-08-13
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US20090088382A1 (en) 2009-04-02
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US8012933B2 (en) 2011-09-06
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US7452864B2 (en) 2008-11-18
CN1744913A (zh) 2006-03-08
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