SE310364B - - Google Patents

Info

Publication number
SE310364B
SE310364B SE2412/63A SE241263A SE310364B SE 310364 B SE310364 B SE 310364B SE 2412/63 A SE2412/63 A SE 2412/63A SE 241263 A SE241263 A SE 241263A SE 310364 B SE310364 B SE 310364B
Authority
SE
Sweden
Application number
SE2412/63A
Inventor
V Torelli
J Cerede
G Amiard
G Nomine
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR890184A external-priority patent/FR1364556A/fr
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of SE310364B publication Critical patent/SE310364B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
    • C07C59/215—Saturated compounds having only one carboxyl group and containing keto groups containing singly bound oxygen containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/46—Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/80—Unsaturated compounds containing keto groups containing rings other than six-membered aromatic rings
    • C07C59/82—Unsaturated compounds containing keto groups containing rings other than six-membered aromatic rings the keto group being part of a ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/38—Unsaturated compounds containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J61/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by contraction of only one ring by one or two atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE2412/63A 1962-03-06 1963-03-05 SE310364B (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR890184A FR1364556A (fr) 1962-03-06 1962-03-06 Nouveau procédé de synthèse de stéroïdes et de composés apparentés et produits utilisés dans ce procédé
FR957460A FR1476509A (fr) 1962-03-06 1963-12-17 Nouveau procédé de syntbèse de stéroïdes et de composés apparentés et produits utilisés dans ce procédé
FR960254A FR1512318A (fr) 1962-03-06 1964-01-14 Dérivés optiquement actifs de la 19-nor testostérone et procédé de préparation
FR964517A FR91612E (fr) 1962-03-06 1964-02-20 Dérivés optiquement actifs de la 19-nor testostérone et procédé de préparation

Publications (1)

Publication Number Publication Date
SE310364B true SE310364B (sr) 1969-04-28

Family

ID=27445406

Family Applications (5)

Application Number Title Priority Date Filing Date
SE2412/63A SE310364B (sr) 1962-03-06 1963-03-05
SE1225764A SE319174B (sr) 1962-03-06 1964-10-12
SE15301/64D SE313306B (sr) 1962-03-06 1964-12-17
SE15298/64A SE309038B (sr) 1962-03-06 1964-12-17
SE15299/64A SE302301B (sr) 1962-03-06 1964-12-17

Family Applications After (4)

Application Number Title Priority Date Filing Date
SE1225764A SE319174B (sr) 1962-03-06 1964-10-12
SE15301/64D SE313306B (sr) 1962-03-06 1964-12-17
SE15298/64A SE309038B (sr) 1962-03-06 1964-12-17
SE15299/64A SE302301B (sr) 1962-03-06 1964-12-17

Country Status (11)

Country Link
US (1) US3413314A (sr)
BE (4) BE657261A (sr)
BR (5) BR6347416D0 (sr)
CH (10) CH424768A (sr)
DE (7) DE1468529C3 (sr)
DK (7) DK121224B (sr)
FR (3) FR1476509A (sr)
GB (11) GB1042631A (sr)
IL (6) IL22638A (sr)
NL (8) NL6414756A (sr)
SE (5) SE310364B (sr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1526962A (fr) * 1967-01-06 1968-05-31 Roussel Uclaf Nouveau procédé de préparation d'un composé gonatriénique et produits en résultant
US3855247A (en) * 1967-12-04 1974-12-17 Syntex Corp Production of unsaturated carbocyclic ketones
US3979458A (en) * 1967-12-04 1976-09-07 Syntex Corporation Production of unsaturated carbocyclic ketones
US3541210A (en) * 1968-04-10 1970-11-17 Sandoz Ag 17-alpha-(2-butyn-1-yl)-substituted steroids
US3897460A (en) * 1968-10-04 1975-07-29 Hoffmann La Roche 3{62 -Tertiarybutoxy-decahydro-benz{8 E{9 indenes
US3927031A (en) * 1968-10-04 1975-12-16 Hoffmann La Roche Stereospecific total steroidal synthesis via substituted C/D-trans indanones
US3929876A (en) * 1968-10-04 1975-12-30 Hoffmann La Roche Stereospecific total steroidal synthesis via substituted C/D-trans indanones
FR2183555B1 (sr) * 1972-05-10 1975-06-20 Roussel Uclaf
US4234491A (en) 1978-06-19 1980-11-18 Syntex (U.S.A.) Inc. Steroid synthesis process using mixed anhydride
US4158012A (en) * 1978-06-19 1979-06-12 Syntex (U.S.A.) Inc. Steroid synthesis process using mixed anhydride
US4400524A (en) * 1981-07-28 1983-08-23 The Upjohn Company Grignard reagents prepared from 5-halopentan-2-one propylene ketals
US4900837A (en) * 1982-05-18 1990-02-13 University Of Florida Brain-specific drug delivery of steroid sex hormones cleaved from pyridinium carboxylates and dihydro-pyridine carboxylate precursors
US5567830A (en) * 1994-02-14 1996-10-22 Cocensys, Inc. Process for synthesis of acetylenic carbinols
DE19503327A1 (de) * 1995-02-02 1996-08-08 Basf Ag Verfahren zur Herstellung von 5-Oxo-6-heptensäurealkylestern sowie neue Zwischenprodukte zu ihrer Herstellung
IL119649A (en) * 1995-11-30 2002-03-10 Akzo Nobel Nv Preparation of Cyclic Kills of History - 3 keto- (5) 10, (-9) 11 steroidadians
ITUB20155260A1 (it) 2015-10-30 2017-04-30 Ind Chimica Srl PROCESSO PER LA PREPARAZIONE DI 17?-idrossi-des-A-androst-9,10-en-5-one

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE632347A (sr) *
US2839537A (en) * 1952-05-12 1958-06-17 Ciba Pharm Prod Inc Tricyclic diketone and process of manufacture
US3019252A (en) * 1959-06-18 1962-01-30 Lab Francais Chimiotherapie Process for the preparation of novel derivatives of cyclopentanonaphthalene and products obtained thereby
US3115507A (en) * 1960-01-22 1963-12-24 Roussel Uclaf New analogs of 19-nor-testosterone, their esters and process of preparation
FR1363113A (fr) * 1960-07-29 1964-06-12 Roussel Uclaf Nouveaux dérivés oestradiéniques
FR1283951A (fr) * 1960-12-28 1962-02-09 Chimiotherapie Lab Franc Nouveau dérivé propylé du phénanthrène et procédé de préparation

Also Published As

Publication number Publication date
GB1096768A (en) 1967-12-29
DE1468897C3 (de) 1978-07-13
CH411858A (fr) 1966-04-30
IL30735A (en) 1970-12-24
DE1468529A1 (de) 1969-04-10
GB1042631A (en) 1966-09-14
BE657261A (sr)
DE1468530B2 (sr) 1979-03-22
GB1096771A (en) 1967-12-29
GB1096767A (en) 1967-12-29
FR1476509A (fr) 1967-04-14
DE1468896A1 (de) 1969-01-16
DK112032B (da) 1968-11-04
DE1468531B1 (de) 1977-03-31
DK127062B (da) 1973-09-17
BR6465401D0 (pt) 1973-07-17
CH436275A (fr) 1967-05-31
BR6565404D0 (pt) 1973-08-02
CH410934A (fr) 1966-04-15
NL6414755A (sr) 1965-06-18
SE313306B (sr) 1969-08-11
BE657263A (sr)
NL6414764A (sr) 1965-06-18
GB1096763A (en) 1967-12-29
DE1518111B2 (de) 1978-08-31
DK121224B (da) 1971-09-27
GB1042633A (en) 1966-09-14
GB1096761A (en) 1967-12-29
SE309038B (sr) 1969-03-10
DK144794B (da) 1982-06-07
GB1057117A (en) 1967-02-01
NL126395C (sr)
BE657260A (sr)
CH433265A (fr) 1967-04-15
CH437272A (fr) 1967-06-15
DK144794C (da) 1982-12-20
NL122142C (sr)
CH450406A (fr) 1968-01-31
FR1512318A (fr) 1968-02-09
GB1096769A (en) 1967-12-29
NL122309C (sr)
DE1518111A1 (de) 1972-03-16
BE657262A (sr)
GB1096762A (en) 1967-12-29
CH424768A (fr) 1966-11-30
DK114131B (da) 1969-06-02
IL22637A (en) 1969-02-27
US3413314A (en) 1968-11-26
DE1468897A1 (de) 1969-01-02
NL6414702A (sr) 1965-06-18
FR91612E (fr) 1968-07-19
NL123143C (sr)
IL30736A (en) 1969-01-29
CH436274A (fr) 1967-05-31
IL22636A (en) 1968-12-26
BR6465402D0 (pt) 1973-07-17
DE1468530C3 (sr) 1979-12-20
GB1042632A (en) 1966-09-14
BR6465403D0 (pt) 1973-08-02
SE319174B (sr) 1970-01-12
DE1468529C3 (de) 1979-10-31
DE1468895A1 (de) 1969-01-23
SE302301B (sr) 1968-07-15
IL22635A (en) 1969-01-29
DK111956B (da) 1968-10-28
DE1518111C3 (de) 1979-04-26
IL22638A (en) 1969-03-27
DE1468530A1 (de) 1969-03-06
CH427782A (fr) 1967-01-15
DE1468529B2 (de) 1979-03-08
BR6347416D0 (pt) 1973-08-28
NL6414756A (sr) 1965-06-18
DK114687B (da) 1969-07-28
CH436273A (fr) 1967-05-31

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