SE314773B - - Google Patents
Info
- Publication number
- SE314773B SE314773B SE157363A SE157363A SE314773B SE 314773 B SE314773 B SE 314773B SE 157363 A SE157363 A SE 157363A SE 157363 A SE157363 A SE 157363A SE 314773 B SE314773 B SE 314773B
- Authority
- SE
- Sweden
- Prior art keywords
- cephalosporin
- aqueous solution
- adsorbing
- purified
- known methods
- Prior art date
Links
- 239000007864 aqueous solution Substances 0.000 abstract 2
- HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 229950008644 adicillin Drugs 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- MIFYHUACUWQUKT-GPUHXXMPSA-N penicillin N Chemical compound OC(=O)[C@H]1C(C)(C)S[C@@H]2[C@H](NC(=O)CCC[C@@H](N)C(O)=O)C(=O)N21 MIFYHUACUWQUKT-GPUHXXMPSA-N 0.000 abstract 1
- 238000012799 strong cation exchange Methods 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical group OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/12—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/06—Cephalosporin C; Derivatives thereof
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Cephalosporin C is purified by adsorbing it from an aqueous solution on to strong cation exchange material containing sulphonic acid groups and eluting adsorbed material with an alkaline reagent. The aqueous solution may be a fermentation medium from which Cephalosporin N and chloride ions have been removed by known methods.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5670/62A GB1036125A (en) | 1962-02-14 | 1962-02-14 | Process for the purification of cephalosporin c |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE314773B true SE314773B (en) | 1969-09-15 |
Family
ID=9800446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE157363A SE314773B (en) | 1962-02-14 | 1963-02-13 |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB1036125A (en) |
| SE (1) | SE314773B (en) |
-
1962
- 1962-02-14 GB GB5670/62A patent/GB1036125A/en not_active Expired
-
1963
- 1963-02-13 SE SE157363A patent/SE314773B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1036125A (en) | 1966-07-13 |
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