SE394820B - Sett att till en i vatten oloslig polymer kovalent binda biologiskt verksamma elektrolyter, sasom aminosyror, peptider, proteiner, nukleotider och nukleinsyror genom reaktion med en sadan polymer innehallande ... - Google Patents

Sett att till en i vatten oloslig polymer kovalent binda biologiskt verksamma elektrolyter, sasom aminosyror, peptider, proteiner, nukleotider och nukleinsyror genom reaktion med en sadan polymer innehallande ...

Info

Publication number
SE394820B
SE394820B SE7000843A SE84370A SE394820B SE 394820 B SE394820 B SE 394820B SE 7000843 A SE7000843 A SE 7000843A SE 84370 A SE84370 A SE 84370A SE 394820 B SE394820 B SE 394820B
Authority
SE
Sweden
Prior art keywords
coolantly
waterolo
activately
bully
nucleotides
Prior art date
Application number
SE7000843A
Other languages
English (en)
Inventor
N Fornstedt
L Sundberg
C I R Eklund
J Porath
R E Axen
Original Assignee
Exploaterings Ab Tbf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exploaterings Ab Tbf filed Critical Exploaterings Ab Tbf
Priority to SE7000843A priority Critical patent/SE394820B/sv
Priority to DE19712102514 priority patent/DE2102514B2/de
Priority to CA103,290A priority patent/CA1000687A/en
Priority to FR7102188A priority patent/FR2077297B1/fr
Priority to JP711941A priority patent/JPS5623588B1/ja
Priority to NL7100902A priority patent/NL7100902A/xx
Priority to GB2018271A priority patent/GB1343703A/en
Priority to US00433245A priority patent/US3853708A/en
Publication of SE394820B publication Critical patent/SE394820B/sv

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6427—Chymotrypsins (3.4.21.1; 3.4.21.2); Trypsin (3.4.21.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/06—Peptides being immobilised on, or in, an organic carrier attached to the carrier via a bridging agent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SE7000843A 1970-01-23 1970-01-23 Sett att till en i vatten oloslig polymer kovalent binda biologiskt verksamma elektrolyter, sasom aminosyror, peptider, proteiner, nukleotider och nukleinsyror genom reaktion med en sadan polymer innehallande ... SE394820B (sv)

Priority Applications (8)

Application Number Priority Date Filing Date Title
SE7000843A SE394820B (sv) 1970-01-23 1970-01-23 Sett att till en i vatten oloslig polymer kovalent binda biologiskt verksamma elektrolyter, sasom aminosyror, peptider, proteiner, nukleotider och nukleinsyror genom reaktion med en sadan polymer innehallande ...
DE19712102514 DE2102514B2 (de) 1970-01-23 1971-01-20 Verfahren zur chemischen kupplung von biologisch wirksamen stoffen an ein hydrophiles polymer
CA103,290A CA1000687A (en) 1970-01-23 1971-01-21 Method of chemically coupling biologically active substances to oxirane-containing polymers
FR7102188A FR2077297B1 (sv) 1970-01-23 1971-01-22
JP711941A JPS5623588B1 (sv) 1970-01-23 1971-01-22
NL7100902A NL7100902A (sv) 1970-01-23 1971-01-22
GB2018271A GB1343703A (en) 1970-01-23 1971-04-19 Method of chemically coupling biologically active substances to oxirane-containing polymers
US00433245A US3853708A (en) 1970-01-23 1974-01-14 Coupling biologically active substances to oxirane-containing polymers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7000843A SE394820B (sv) 1970-01-23 1970-01-23 Sett att till en i vatten oloslig polymer kovalent binda biologiskt verksamma elektrolyter, sasom aminosyror, peptider, proteiner, nukleotider och nukleinsyror genom reaktion med en sadan polymer innehallande ...

Publications (1)

Publication Number Publication Date
SE394820B true SE394820B (sv) 1977-07-11

Family

ID=20257189

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7000843A SE394820B (sv) 1970-01-23 1970-01-23 Sett att till en i vatten oloslig polymer kovalent binda biologiskt verksamma elektrolyter, sasom aminosyror, peptider, proteiner, nukleotider och nukleinsyror genom reaktion med en sadan polymer innehallande ...

Country Status (7)

Country Link
JP (1) JPS5623588B1 (sv)
CA (1) CA1000687A (sv)
DE (1) DE2102514B2 (sv)
FR (1) FR2077297B1 (sv)
GB (1) GB1343703A (sv)
NL (1) NL7100902A (sv)
SE (1) SE394820B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3844892A (en) * 1972-12-19 1974-10-29 Gulf Research Development Co Method of immobilizing enzymes
FR2450263A1 (fr) * 1979-02-28 1980-09-26 Dow Chemical Co Procede pour coupler une proteine sur un latex portant des groupes epoxyde et produits obtenus par ce procede
DE3344912A1 (de) * 1983-12-13 1985-06-20 Hoechst Ag, 6230 Frankfurt Vernetzte polymerisate, verfahren zu ihrer herstellung und ihre anwendung
JPS61191700A (ja) * 1984-12-28 1986-08-26 ジエネツクス・コ−ポレイシヨン エポキシ−ポリアルキレンイミン共重合体による生体物質の固定
DE3500180A1 (de) * 1985-01-04 1986-07-10 Ernst Prof. Dr. 7400 Tübingen Bayer Pfropfcopolymerisate aus vernetzten polymeren und polyoxyethylen, verfahren zu ihrer herstellung und ihre verwendung
US4882226A (en) * 1986-09-23 1989-11-21 Akzo N.V. Carrier material for use in chromatography or carrying out enzymatic reactions
DE3827867A1 (de) * 1988-08-17 1990-02-22 Hoechst Ag Verfahren zur herstellung von cyclischen harnstoffen
US5278303A (en) * 1992-06-12 1994-01-11 University Of Toronto Innovations Foundation Polymer-supported solution synthesis of oligosaccharides
US5616698A (en) * 1994-01-10 1997-04-01 University Of Toronto Innovations Foundation Polymer-supported solution synthesis of oligosaccharides
WO2008139637A1 (en) * 2007-05-14 2008-11-20 Kazufumi Ogawa Pharmaceutical preparation and manufacturing method thereof
CN111965341B (zh) * 2020-08-10 2023-04-11 武汉菲恩生物科技有限公司 一种基于葡聚糖的HRP-羊抗鼠IgG标记抗体及其制备方法

Also Published As

Publication number Publication date
JPS5623588B1 (sv) 1981-06-01
NL7100902A (sv) 1971-07-27
DE2102514B2 (de) 1977-08-18
FR2077297A1 (sv) 1971-10-22
GB1343703A (en) 1974-01-16
DE2102514A1 (de) 1971-07-29
FR2077297B1 (sv) 1976-03-19
CA1000687A (en) 1976-11-30

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