SE430340B - Forfarande for framstellning av nya nitrosokarbamidderivat - Google Patents
Forfarande for framstellning av nya nitrosokarbamidderivatInfo
- Publication number
- SE430340B SE430340B SE7508840A SE7508840A SE430340B SE 430340 B SE430340 B SE 430340B SE 7508840 A SE7508840 A SE 7508840A SE 7508840 A SE7508840 A SE 7508840A SE 430340 B SE430340 B SE 430340B
- Authority
- SE
- Sweden
- Prior art keywords
- group
- hydroxy
- derivatives
- substituted
- nitrosocarbamide
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- HOVAGTYPODGVJG-UVSYOFPXSA-N (3s,5r)-2-(hydroxymethyl)-6-methoxyoxane-3,4,5-triol Chemical compound COC1OC(CO)[C@@H](O)C(O)[C@H]1O HOVAGTYPODGVJG-UVSYOFPXSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 abstract 1
- 125000003147 glycosyl group Chemical group 0.000 abstract 1
- -1 hydroxy-substituted cyclohexyl group Chemical group 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- HOVAGTYPODGVJG-UHFFFAOYSA-N methyl beta-galactoside Natural products COC1OC(CO)C(O)C(O)C1O HOVAGTYPODGVJG-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- OSTGTTZJOCZWJG-UHFFFAOYSA-N nitrosourea Chemical class NC(=O)N=NO OSTGTTZJOCZWJG-UHFFFAOYSA-N 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229930190553 ribostamycin Natural products 0.000 abstract 1
- NSKGQURZWSPSBC-NLZFXWNVSA-N ribostamycin Chemical compound N[C@H]1[C@H](O)[C@@H](O)[C@H](CN)O[C@@H]1O[C@@H]1[C@@H](O[C@H]2[C@@H]([C@@H](O)[C@H](CO)O2)O)[C@H](O)[C@@H](N)C[C@H]1N NSKGQURZWSPSBC-NLZFXWNVSA-N 0.000 abstract 1
- 229960003485 ribostamycin Drugs 0.000 abstract 1
- NSKGQURZWSPSBC-UHFFFAOYSA-N ribostamycin A Natural products NC1C(O)C(O)C(CN)OC1OC1C(OC2C(C(O)C(CO)O2)O)C(O)C(N)CC1N NSKGQURZWSPSBC-UHFFFAOYSA-N 0.000 abstract 1
- 150000005846 sugar alcohols Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/66—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to halogen atoms or to nitro or nitroso groups
- C07C275/68—N-nitroso ureas
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
- C07H15/23—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin, xylostatin, ribostamycin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP49090266A JPS5126876A (en) | 1974-08-08 | 1974-08-08 | Shinkina nitorosonyosojudotaino seizohoho |
| JP12431974A JPS5152128A (ja) | 1974-10-30 | 1974-10-30 | Nitorosonyosojudotaino shinseizoho |
| JP3113175A JPS51108043A (ja) | 1975-03-17 | 1975-03-17 | Nitorosonyosokagobutsunoseiho |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7508840L SE7508840L (sv) | 1976-02-09 |
| SE430340B true SE430340B (sv) | 1983-11-07 |
Family
ID=27287217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7508840A SE430340B (sv) | 1974-08-08 | 1975-08-05 | Forfarande for framstellning av nya nitrosokarbamidderivat |
Country Status (11)
| Country | Link |
|---|---|
| AT (1) | AT351555B (de) |
| CH (1) | CH619967A5 (de) |
| DE (1) | DE2535048C3 (de) |
| ES (1) | ES440147A1 (de) |
| FR (1) | FR2281102A1 (de) |
| GB (1) | GB1507099A (de) |
| HU (1) | HU175174B (de) |
| IL (1) | IL47842A (de) |
| NL (1) | NL7509445A (de) |
| SE (1) | SE430340B (de) |
| YU (1) | YU39743B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5331664A (en) * | 1976-09-02 | 1978-03-25 | Suami T | Production of novel nitroso urea derivatives |
| US4182757A (en) * | 1977-07-29 | 1980-01-08 | Tanabe Seiyaku Co., Ltd. | Novel nitrosourea compounds and process for preparing the same |
| JPS5940400B2 (ja) * | 1980-03-24 | 1984-09-29 | わかもと製薬株式会社 | 新規d−アロ−ス誘導体及びこれを有効成分とする抗腫瘍剤 |
| DE3323095A1 (de) * | 1983-06-27 | 1985-01-03 | Institut organičeskoj chimii Akademii Nauk Kirgizskoj SSR, Frunze | Verfahren zur herstellung von n-alkyl-n'-glykosyl-n-nitrosourethan |
| CA2357977A1 (en) * | 1998-12-29 | 2000-07-06 | Donald R. Kahn | Method for prevention or treatment of acute allograft rejection and a pharmaceutical composition therefor |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH518270A (de) * | 1969-03-07 | 1972-01-31 | Hoffmann La Roche | Verfahren zur Herstellung von Nitrosoharnstoffverbindungen |
| JPS4843333B1 (de) * | 1970-04-25 | 1973-12-18 |
-
1975
- 1975-07-30 IL IL47842A patent/IL47842A/xx unknown
- 1975-07-30 GB GB31941/75A patent/GB1507099A/en not_active Expired
- 1975-08-05 SE SE7508840A patent/SE430340B/xx unknown
- 1975-08-06 HU HU75SU897A patent/HU175174B/hu unknown
- 1975-08-06 DE DE2535048A patent/DE2535048C3/de not_active Expired
- 1975-08-06 FR FR7525015A patent/FR2281102A1/fr active Granted
- 1975-08-07 YU YU2034/75A patent/YU39743B/xx unknown
- 1975-08-07 NL NL7509445A patent/NL7509445A/xx not_active Application Discontinuation
- 1975-08-07 CH CH1033175A patent/CH619967A5/de not_active IP Right Cessation
- 1975-08-08 ES ES440147A patent/ES440147A1/es not_active Expired
- 1975-08-08 AT AT618475A patent/AT351555B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CH619967A5 (en) | 1980-10-31 |
| NL7509445A (nl) | 1976-02-10 |
| SE7508840L (sv) | 1976-02-09 |
| ES440147A1 (es) | 1977-06-16 |
| HU175174B (hu) | 1980-05-28 |
| IL47842A (en) | 1980-07-31 |
| DE2535048C3 (de) | 1980-02-14 |
| DE2535048A1 (de) | 1976-02-19 |
| FR2281102B1 (de) | 1979-04-06 |
| AT351555B (de) | 1979-08-10 |
| DE2535048B2 (de) | 1979-06-07 |
| ATA618475A (de) | 1979-01-15 |
| FR2281102A1 (fr) | 1976-03-05 |
| YU203475A (en) | 1982-02-28 |
| IL47842A0 (en) | 1975-10-15 |
| AU8380475A (en) | 1977-02-10 |
| GB1507099A (en) | 1978-04-12 |
| YU39743B (en) | 1985-04-30 |
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