SE444647B - Forfarande for framstellning av ett fast, stabilt endotoxin- och pyrogenfritt tymosin 5-preparat - Google Patents

Forfarande for framstellning av ett fast, stabilt endotoxin- och pyrogenfritt tymosin 5-preparat

Info

Publication number
SE444647B
SE444647B SE7802014A SE7802014A SE444647B SE 444647 B SE444647 B SE 444647B SE 7802014 A SE7802014 A SE 7802014A SE 7802014 A SE7802014 A SE 7802014A SE 444647 B SE444647 B SE 444647B
Authority
SE
Sweden
Prior art keywords
preparation
thymosin fraction
solid
permeate
reconstitution
Prior art date
Application number
SE7802014A
Other languages
English (en)
Swedish (sv)
Other versions
SE7802014L (sv
Inventor
W C Mcgregor
H L Newmark
A H Ramel
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE7802014L publication Critical patent/SE7802014L/xx
Publication of SE444647B publication Critical patent/SE444647B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2292—Thymosin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
SE7802014A 1977-02-22 1978-02-21 Forfarande for framstellning av ett fast, stabilt endotoxin- och pyrogenfritt tymosin 5-preparat SE444647B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/770,480 US4082737A (en) 1977-02-22 1977-02-22 Stabilized thymosin composition and method

Publications (2)

Publication Number Publication Date
SE7802014L SE7802014L (sv) 1978-08-23
SE444647B true SE444647B (sv) 1986-04-28

Family

ID=25088687

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7802014A SE444647B (sv) 1977-02-22 1978-02-21 Forfarande for framstellning av ett fast, stabilt endotoxin- och pyrogenfritt tymosin 5-preparat

Country Status (20)

Country Link
US (1) US4082737A (de)
JP (1) JPS53104719A (de)
AT (1) AT363177B (de)
AU (1) AU516946B2 (de)
BE (1) BE864139A (de)
CA (1) CA1099633A (de)
CH (1) CH632164A5 (de)
DE (1) DE2807202C2 (de)
DK (1) DK78378A (de)
FR (1) FR2380782A1 (de)
GB (1) GB1546027A (de)
IE (1) IE46409B1 (de)
IL (1) IL54063A0 (de)
IT (1) IT1092337B (de)
LU (1) LU79090A1 (de)
NL (1) NL189281C (de)
NZ (1) NZ186489A (de)
PH (1) PH13858A (de)
SE (1) SE444647B (de)
ZA (1) ZA78890B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2732587A1 (de) * 1976-09-22 1978-03-23 Bach Jean Francois Polypeptid mit thymischer wirksamkeit
US4148788A (en) * 1978-01-23 1979-04-10 Hoffmann-La Roche Inc. Synthesis of thymosin α1
US4239498A (en) * 1978-11-27 1980-12-16 Rule Allyn H Method of preparing thymic factors and composition
US4264571A (en) * 1979-01-22 1981-04-28 George Washington University Radioimmunoassay of thymosin α1
EP0057702A1 (de) * 1980-08-08 1982-08-18 Rak-A-Van Pty Limited Verbessertes regal
US4427783A (en) 1981-12-14 1984-01-24 Hoffmann-La Roche Inc. Immunoassay of thymosin α1
US4389343A (en) * 1981-12-24 1983-06-21 Hoffmann-La Roche Inc. Immunopotentiating peptides from thymus
US4388234A (en) * 1981-12-28 1983-06-14 Hoffmann-La Roche Inc. Peptide isolation
US4614731A (en) * 1983-09-15 1986-09-30 Hoffmann-La Roche Inc. Peptide having immunopotentiating activity similar to thymosin alpha1
US4659694A (en) * 1983-10-27 1987-04-21 Hoffmann-La Roche Inc. Prothymosin alpha
US4814434A (en) * 1984-02-03 1989-03-21 Ventres Laboratories, Inc. Inducer of T-suppressor cells
DE3633651A1 (de) * 1986-10-03 1988-04-14 Alfred Dr Dick Verwendung von fraktionen aus thymus- und milzextrakten zur behandlung der psoriasis
US5273963A (en) * 1991-03-29 1993-12-28 The George Washington University Compositions and methods for treating small cell and nonsmall cell lung cancers
JP4404866B2 (ja) 2006-03-03 2010-01-27 ゼライス株式会社 エンドトキシン含有量を低減したゼラチンの製造方法および低エンドトキシンゼラチン

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002602A (en) * 1974-03-11 1977-01-11 Gideon Goldstein Ubiquitous immunopoietic polypeptide (UBIP) and methods
US4010148A (en) * 1975-05-12 1977-03-01 Board Of Regents Of The University Of Texas System Purified thymosin and process
US4002740A (en) * 1975-08-21 1977-01-11 Gideon Goldstein Tridecapeptide compositions and methods

Also Published As

Publication number Publication date
NL7801422A (nl) 1978-08-24
PH13858A (en) 1980-10-22
FR2380782B1 (de) 1980-01-18
IT1092337B (it) 1985-07-06
NZ186489A (en) 1981-01-23
IE780335L (en) 1978-08-22
FR2380782A1 (fr) 1978-09-15
IL54063A0 (en) 1978-04-30
BE864139A (fr) 1978-08-21
DE2807202A1 (de) 1978-08-24
AU516946B2 (en) 1981-07-02
AU3334378A (en) 1979-08-23
ATA124578A (de) 1980-12-15
IT7819791A0 (it) 1978-01-30
IE46409B1 (en) 1983-06-01
US4082737A (en) 1978-04-04
NL189281C (nl) 1993-03-01
AT363177B (de) 1981-07-10
GB1546027A (en) 1979-05-16
JPS618806B2 (de) 1986-03-18
JPS53104719A (en) 1978-09-12
LU79090A1 (fr) 1979-05-25
ZA78890B (en) 1979-01-31
DE2807202C2 (de) 1987-04-02
NL189281B (nl) 1992-10-01
SE7802014L (sv) 1978-08-23
CA1099633A (en) 1981-04-21
DK78378A (da) 1978-08-23
CH632164A5 (de) 1982-09-30

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