SE444647B - Forfarande for framstellning av ett fast, stabilt endotoxin- och pyrogenfritt tymosin 5-preparat - Google Patents

Forfarande for framstellning av ett fast, stabilt endotoxin- och pyrogenfritt tymosin 5-preparat

Info

Publication number
SE444647B
SE444647B SE7802014A SE7802014A SE444647B SE 444647 B SE444647 B SE 444647B SE 7802014 A SE7802014 A SE 7802014A SE 7802014 A SE7802014 A SE 7802014A SE 444647 B SE444647 B SE 444647B
Authority
SE
Sweden
Prior art keywords
preparation
thymosin fraction
solid
permeate
reconstitution
Prior art date
Application number
SE7802014A
Other languages
English (en)
Swedish (sv)
Other versions
SE7802014L (sv
Inventor
W C Mcgregor
H L Newmark
A H Ramel
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE7802014L publication Critical patent/SE7802014L/xx
Publication of SE444647B publication Critical patent/SE444647B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2292—Thymosin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
SE7802014A 1977-02-22 1978-02-21 Forfarande for framstellning av ett fast, stabilt endotoxin- och pyrogenfritt tymosin 5-preparat SE444647B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/770,480 US4082737A (en) 1977-02-22 1977-02-22 Stabilized thymosin composition and method

Publications (2)

Publication Number Publication Date
SE7802014L SE7802014L (sv) 1978-08-23
SE444647B true SE444647B (sv) 1986-04-28

Family

ID=25088687

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7802014A SE444647B (sv) 1977-02-22 1978-02-21 Forfarande for framstellning av ett fast, stabilt endotoxin- och pyrogenfritt tymosin 5-preparat

Country Status (20)

Country Link
US (1) US4082737A (fr)
JP (1) JPS53104719A (fr)
AT (1) AT363177B (fr)
AU (1) AU516946B2 (fr)
BE (1) BE864139A (fr)
CA (1) CA1099633A (fr)
CH (1) CH632164A5 (fr)
DE (1) DE2807202C2 (fr)
DK (1) DK78378A (fr)
FR (1) FR2380782A1 (fr)
GB (1) GB1546027A (fr)
IE (1) IE46409B1 (fr)
IL (1) IL54063A0 (fr)
IT (1) IT1092337B (fr)
LU (1) LU79090A1 (fr)
NL (1) NL189281C (fr)
NZ (1) NZ186489A (fr)
PH (1) PH13858A (fr)
SE (1) SE444647B (fr)
ZA (1) ZA78890B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2732587A1 (de) * 1976-09-22 1978-03-23 Bach Jean Francois Polypeptid mit thymischer wirksamkeit
US4148788A (en) * 1978-01-23 1979-04-10 Hoffmann-La Roche Inc. Synthesis of thymosin α1
US4239498A (en) * 1978-11-27 1980-12-16 Rule Allyn H Method of preparing thymic factors and composition
US4264571A (en) * 1979-01-22 1981-04-28 George Washington University Radioimmunoassay of thymosin α1
WO1982000407A1 (fr) * 1980-08-08 1982-02-18 Sykes A Systeme d'etageres ameliore
US4427783A (en) 1981-12-14 1984-01-24 Hoffmann-La Roche Inc. Immunoassay of thymosin α1
US4389343A (en) * 1981-12-24 1983-06-21 Hoffmann-La Roche Inc. Immunopotentiating peptides from thymus
US4388234A (en) * 1981-12-28 1983-06-14 Hoffmann-La Roche Inc. Peptide isolation
US4614731A (en) * 1983-09-15 1986-09-30 Hoffmann-La Roche Inc. Peptide having immunopotentiating activity similar to thymosin alpha1
US4659694A (en) * 1983-10-27 1987-04-21 Hoffmann-La Roche Inc. Prothymosin alpha
US4814434A (en) * 1984-02-03 1989-03-21 Ventres Laboratories, Inc. Inducer of T-suppressor cells
DE3633651A1 (de) * 1986-10-03 1988-04-14 Alfred Dr Dick Verwendung von fraktionen aus thymus- und milzextrakten zur behandlung der psoriasis
US5273963A (en) * 1991-03-29 1993-12-28 The George Washington University Compositions and methods for treating small cell and nonsmall cell lung cancers
JP4404866B2 (ja) 2006-03-03 2010-01-27 ゼライス株式会社 エンドトキシン含有量を低減したゼラチンの製造方法および低エンドトキシンゼラチン

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002602A (en) * 1974-03-11 1977-01-11 Gideon Goldstein Ubiquitous immunopoietic polypeptide (UBIP) and methods
US4010148A (en) * 1975-05-12 1977-03-01 Board Of Regents Of The University Of Texas System Purified thymosin and process
US4002740A (en) * 1975-08-21 1977-01-11 Gideon Goldstein Tridecapeptide compositions and methods

Also Published As

Publication number Publication date
SE7802014L (sv) 1978-08-23
DK78378A (da) 1978-08-23
AU516946B2 (en) 1981-07-02
CA1099633A (fr) 1981-04-21
ATA124578A (de) 1980-12-15
DE2807202C2 (de) 1987-04-02
NL7801422A (nl) 1978-08-24
PH13858A (en) 1980-10-22
NZ186489A (en) 1981-01-23
GB1546027A (en) 1979-05-16
JPS53104719A (en) 1978-09-12
BE864139A (fr) 1978-08-21
AT363177B (de) 1981-07-10
IT7819791A0 (it) 1978-01-30
LU79090A1 (fr) 1979-05-25
FR2380782B1 (fr) 1980-01-18
IE780335L (en) 1978-08-22
NL189281B (nl) 1992-10-01
NL189281C (nl) 1993-03-01
CH632164A5 (de) 1982-09-30
IT1092337B (it) 1985-07-06
FR2380782A1 (fr) 1978-09-15
IE46409B1 (en) 1983-06-01
JPS618806B2 (fr) 1986-03-18
DE2807202A1 (de) 1978-08-24
ZA78890B (en) 1979-01-31
AU3334378A (en) 1979-08-23
IL54063A0 (en) 1978-04-30
US4082737A (en) 1978-04-04

Similar Documents

Publication Publication Date Title
SE444647B (sv) Forfarande for framstellning av ett fast, stabilt endotoxin- och pyrogenfritt tymosin 5-preparat
KR100609262B1 (ko) 정용 여과로 안정화된 혈액 생성물의 제조 방법
Oldendorf et al. Greater number of capillary endothelial cell mitochondria in brain than in muscle
Royston et al. Increased production of peroxidation products associated with cardiac operations: evidence for free radical generation
US5114932A (en) Hyperosmolar oxyreplete hemosubstitute
PE20000265A1 (es) Composiciones que contienen virus y metodos para concentrar preparados de virus
Lee et al. Ultrapure, stroma-free, polymerized bovine hemoglobin solution: evaluation of renal toxicity
Haywood et al. Epinephrine effects on branchial water and urea flux in rainbow trout
Moore et al. Ultraviolet irradiation of pyrimidine derivatives
EP1348445A1 (fr) Procédé de séparation de virus d'une suspension de protéines par nanofiltration
Enna et al. Phenol red absorption from the rat lung: evidence of carrier transport
Stankowski et al. A combined study of aggregation, membrane affinity and pore activity of natural and modified melittin
Rezende et al. Functional and histopathological renal changes induced in rats by Bothrops jararaca venom.
DE69130736T2 (de) Methode für die präparation von pyridoxyliertem hämoglobin
Burrell et al. Mediators of Pulmonary Injury Induced by Inhalation of Bacterial Endotoxin1-3
ES2224094T3 (es) Procedimiento para preparar seroalbumina normal (humana) esencialmente monomerica.
Chari-Bitron Stabilization of rat erythrocyte membrane by△ 1-tetrahydrocannabinol
Hempling et al. Maturation of membrane function: The permeability of the rat erythroblastic leukemic cell to water and to non‐electrolytes
Pai et al. Kinetics of aluminum in rats I: Dose‐dependent elimination from blood after intravenous administration
Dalgliesh Permeation of bovine erythrocytes with glycerol and their protection during rapid freezing and thawing
Seifter et al. Relation of endocrines and clearing factor inhibitors to hyperlipemia in fasted animals.
Williams et al. Renal handling of aromatic amino acids, sugar, and standard glomerular markers in winter flounder
Pegg et al. Renal preservation by hypothermic perfusion. III. The lack of influence of pulsatile flow
Pegg et al. Renal preservation by hypothermic perfusion. IV. The use of gelatin polypeptides as the sole colloid
EP3154597B1 (fr) Procédés de préparation d'une nouvelle génération de produits klh sans danger biologique utilisés pour le traitement du cancer, pour le développement de vaccins conjugués et en tant qu'agents stimulants

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7802014-6

Format of ref document f/p: F