SE454885B - Polymerbelagda partiklar med immobiliserade metalljoner pa sin yta jemte forfarande for framstellning derav - Google Patents

Polymerbelagda partiklar med immobiliserade metalljoner pa sin yta jemte forfarande for framstellning derav

Info

Publication number: SE454885B
Authority: SE; Sweden
Prior art keywords: solid phase; polymer; polyamide; product according; product
Prior art date: 1984-10-19

Application number

SE8405241A

Other languages

English (en)

Swedish (sv)

Other versions

SE8405241L (sv

SE8405241D0 (sv

Inventor

J Porath

M Lindahl

Original Assignee

Exploaterings Ab Tbf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-19

Filing date

1984-10-19

Publication date

1988-06-06

1984-10-19 Application filed by Exploaterings Ab Tbf filed Critical Exploaterings Ab Tbf

1984-10-19 Priority to SE8405241A priority Critical patent/SE454885B/sv

1984-10-19 Publication of SE8405241D0 publication Critical patent/SE8405241D0/xx

1985-10-08 Priority to DE8585850315T priority patent/DE3583373D1/de

1985-10-08 Priority to EP85850315A priority patent/EP0179039B1/de

1985-10-11 Priority to US06/786,857 priority patent/US4677027A/en

1985-10-19 Priority to JP60234380A priority patent/JPS61118398A/ja

1986-04-20 Publication of SE8405241L publication Critical patent/SE8405241L/xx

1988-06-06 Publication of SE454885B publication Critical patent/SE454885B/sv

Links

229920000642 polymer Polymers 0.000 title claims description 33
238000000034 method Methods 0.000 title claims description 22
239000002245 particle Substances 0.000 title claims description 22
229910052751 metal Inorganic materials 0.000 title claims description 17
239000002184 metal Substances 0.000 title claims description 17
SZVJSHCCFOBDDC-UHFFFAOYSA-N iron(II,III) oxide Inorganic materials O=[Fe]O[Fe]O[Fe]=O SZVJSHCCFOBDDC-UHFFFAOYSA-N 0.000 claims description 15
239000007790 solid phase Substances 0.000 claims description 15
229910021645 metal ion Inorganic materials 0.000 claims description 11
AFOSIXZFDONLBT-UHFFFAOYSA-N divinyl sulfone Chemical compound C=CS(=O)(=O)C=C AFOSIXZFDONLBT-UHFFFAOYSA-N 0.000 claims description 9
229920000936 Agarose Polymers 0.000 claims description 8
229920002307 Dextran Polymers 0.000 claims description 8
239000004952 Polyamide Substances 0.000 claims description 8
229920002647 polyamide Polymers 0.000 claims description 8
102000004169 proteins and genes Human genes 0.000 claims description 7
108090000623 proteins and genes Proteins 0.000 claims description 7
239000002738 chelating agent Substances 0.000 claims description 6
150000005846 sugar alcohols Polymers 0.000 claims description 6
229920000768 polyamine Polymers 0.000 claims description 5
239000000126 substance Substances 0.000 claims description 5
239000003153 chemical reaction reagent Substances 0.000 claims description 4
150000004676 glycans Chemical class 0.000 claims description 4
229920000728 polyester Polymers 0.000 claims description 4
229920001282 polysaccharide Polymers 0.000 claims description 4
239000005017 polysaccharide Substances 0.000 claims description 4
229920003169 water-soluble polymer Polymers 0.000 claims description 4
239000004721 Polyphenylene oxide Substances 0.000 claims description 3
239000013522 chelant Substances 0.000 claims description 3
239000012071 phase Substances 0.000 claims description 3
229920000570 polyether Polymers 0.000 claims description 3
238000000926 separation method Methods 0.000 claims description 3
239000004971 Cross linker Substances 0.000 claims description 2
241000700605 Viruses Species 0.000 claims description 2
150000001412 amines Chemical class 0.000 claims description 2
125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
229910052976 metal sulfide Inorganic materials 0.000 claims description 2
125000001424 substituent group Chemical group 0.000 claims description 2
229920002401 polyacrylamide Polymers 0.000 claims 2
108090000765 processed proteins & peptides Proteins 0.000 claims 2
108091034117 Oligonucleotide Proteins 0.000 claims 1
239000002202 Polyethylene glycol Substances 0.000 claims 1
150000002118 epoxides Chemical class 0.000 claims 1
239000000696 magnetic material Substances 0.000 claims 1
229920001223 polyethylene glycol Polymers 0.000 claims 1
108091033319 polynucleotide Proteins 0.000 claims 1
102000040430 polynucleotide Human genes 0.000 claims 1
239000002157 polynucleotide Substances 0.000 claims 1
RSPCKAHMRANGJZ-UHFFFAOYSA-N thiohydroxylamine Chemical compound SN RSPCKAHMRANGJZ-UHFFFAOYSA-N 0.000 claims 1
239000000047 product Substances 0.000 description 17
238000001179 sorption measurement Methods 0.000 description 13
239000000499 gel Substances 0.000 description 11
239000010410 layer Substances 0.000 description 11
239000000872 buffer Substances 0.000 description 6
239000000243 solution Substances 0.000 description 6
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 5
238000006243 chemical reaction Methods 0.000 description 5
FAGUFWYHJQFNRV-UHFFFAOYSA-N tetraethylenepentamine Chemical compound NCCNCCNCCNCCN FAGUFWYHJQFNRV-UHFFFAOYSA-N 0.000 description 5
HGINCPLSRVDWNT-UHFFFAOYSA-N Acrolein Chemical compound C=CC=O HGINCPLSRVDWNT-UHFFFAOYSA-N 0.000 description 4
239000002253 acid Substances 0.000 description 4
150000001299 aldehydes Chemical class 0.000 description 4
210000004027 cell Anatomy 0.000 description 4
239000010949 copper Substances 0.000 description 4
239000007863 gel particle Substances 0.000 description 4
239000000463 material Substances 0.000 description 4
241000588724 Escherichia coli Species 0.000 description 3
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
229920002472 Starch Polymers 0.000 description 3
230000008878 coupling Effects 0.000 description 3
238000010168 coupling process Methods 0.000 description 3
238000005859 coupling reaction Methods 0.000 description 3
229910001385 heavy metal Inorganic materials 0.000 description 3
150000002500 ions Chemical class 0.000 description 3
150000002736 metal compounds Chemical class 0.000 description 3
239000000203 mixture Substances 0.000 description 3
230000007935 neutral effect Effects 0.000 description 3
239000011734 sodium Substances 0.000 description 3
235000019698 starch Nutrition 0.000 description 3
239000008107 starch Substances 0.000 description 3
238000005406 washing Methods 0.000 description 3
229920001817 Agar Polymers 0.000 description 2
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 description 2
PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
102000004338 Transferrin Human genes 0.000 description 2
108090000901 Transferrin Proteins 0.000 description 2
229910052782 aluminium Inorganic materials 0.000 description 2
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
230000015572 biosynthetic process Effects 0.000 description 2
239000007853 buffer solution Substances 0.000 description 2
229910052793 cadmium Inorganic materials 0.000 description 2
BDOSMKKIYDKNTQ-UHFFFAOYSA-N cadmium atom Chemical compound [Cd] BDOSMKKIYDKNTQ-UHFFFAOYSA-N 0.000 description 2
238000005266 casting Methods 0.000 description 2
239000007795 chemical reaction product Substances 0.000 description 2
239000011248 coating agent Substances 0.000 description 2
238000000576 coating method Methods 0.000 description 2
229910052802 copper Inorganic materials 0.000 description 2
238000010908 decantation Methods 0.000 description 2
238000009792 diffusion process Methods 0.000 description 2
238000005516 engineering process Methods 0.000 description 2
238000011534 incubation Methods 0.000 description 2
229910052742 iron Inorganic materials 0.000 description 2
239000006249 magnetic particle Substances 0.000 description 2
238000002360 preparation method Methods 0.000 description 2
230000008569 process Effects 0.000 description 2
239000000376 reactant Substances 0.000 description 2
230000009467 reduction Effects 0.000 description 2
238000003786 synthesis reaction Methods 0.000 description 2
125000003396 thiol group Chemical group [H]S* 0.000 description 2
239000012581 transferrin Substances 0.000 description 2
WCTAGTRAWPDFQO-UHFFFAOYSA-K trisodium;hydrogen carbonate;carbonate Chemical compound [Na+].[Na+].[Na+].OC([O-])=O.[O-]C([O-])=O WCTAGTRAWPDFQO-UHFFFAOYSA-K 0.000 description 2
CKRNQNYGXBRTOB-UHFFFAOYSA-N 2-(aminomethyl)quinolin-8-ol Chemical compound C1=CC=C(O)C2=NC(CN)=CC=C21 CKRNQNYGXBRTOB-UHFFFAOYSA-N 0.000 description 1
WFIYPADYPQQLNN-UHFFFAOYSA-N 2-[2-(4-bromopyrazol-1-yl)ethyl]isoindole-1,3-dione Chemical class C1=C(Br)C=NN1CCN1C(=O)C2=CC=CC=C2C1=O WFIYPADYPQQLNN-UHFFFAOYSA-N 0.000 description 1
ZSLUVFAKFWKJRC-IGMARMGPSA-N 232Th Chemical compound [232Th] ZSLUVFAKFWKJRC-IGMARMGPSA-N 0.000 description 1
CERZMXAJYMMUDR-QBTAGHCHSA-N 5-amino-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid Chemical compound N[C@@H]1[C@@H](O)CC(O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO CERZMXAJYMMUDR-QBTAGHCHSA-N 0.000 description 1
239000005725 8-Hydroxyquinoline Substances 0.000 description 1
SLBPIHCMXPQAIQ-UHFFFAOYSA-N 8-hydroxyquinoline-2-carbaldehyde Chemical compound C1=C(C=O)N=C2C(O)=CC=CC2=C1 SLBPIHCMXPQAIQ-UHFFFAOYSA-N 0.000 description 1
241000972773 Aulopiformes Species 0.000 description 1
BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 description 1
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
108010052285 Membrane Proteins Proteins 0.000 description 1
229920000881 Modified starch Polymers 0.000 description 1
BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
229910052776 Thorium Inorganic materials 0.000 description 1
229910052770 Uranium Inorganic materials 0.000 description 1
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 description 1
230000004913 activation Effects 0.000 description 1
239000012190 activator Substances 0.000 description 1
239000002156 adsorbate Substances 0.000 description 1
239000008272 agar Substances 0.000 description 1
239000012670 alkaline solution Substances 0.000 description 1
125000000217 alkyl group Chemical group 0.000 description 1
125000003118 aryl group Chemical group 0.000 description 1
230000001363 autoimmune Effects 0.000 description 1
239000010953 base metal Substances 0.000 description 1
230000008901 benefit Effects 0.000 description 1
UCMIRNVEIXFBKS-UHFFFAOYSA-N beta-alanine Chemical compound NCCC(O)=O UCMIRNVEIXFBKS-UHFFFAOYSA-N 0.000 description 1
230000001588 bifunctional effect Effects 0.000 description 1
229920001222 biopolymer Polymers 0.000 description 1
239000008280 blood Substances 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
KDPAWGWELVVRCH-UHFFFAOYSA-M bromoacetate Chemical compound [O-]C(=O)CBr KDPAWGWELVVRCH-UHFFFAOYSA-M 0.000 description 1
238000005119 centrifugation Methods 0.000 description 1
230000008859 change Effects 0.000 description 1
238000005345 coagulation Methods 0.000 description 1
230000015271 coagulation Effects 0.000 description 1
229910017052 cobalt Inorganic materials 0.000 description 1
239000010941 cobalt Substances 0.000 description 1
GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
230000009918 complex formation Effects 0.000 description 1
239000002131 composite material Substances 0.000 description 1
238000009833 condensation Methods 0.000 description 1
230000005494 condensation Effects 0.000 description 1
150000004696 coordination complex Chemical class 0.000 description 1
239000007771 core particle Substances 0.000 description 1
229920006037 cross link polymer Polymers 0.000 description 1
238000004132 cross linking Methods 0.000 description 1
230000001086 cytosolic effect Effects 0.000 description 1
230000006735 deficit Effects 0.000 description 1
239000012153 distilled water Substances 0.000 description 1
238000009826 distribution Methods 0.000 description 1
230000000694 effects Effects 0.000 description 1
WBJINCZRORDGAQ-UHFFFAOYSA-N ethyl formate Chemical compound CCOC=O WBJINCZRORDGAQ-UHFFFAOYSA-N 0.000 description 1
239000012065 filter cake Substances 0.000 description 1
210000003495 flagella Anatomy 0.000 description 1
125000002485 formyl group Chemical group [H]C(*)=O 0.000 description 1
PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
229910052737 gold Inorganic materials 0.000 description 1
239000010931 gold Substances 0.000 description 1
229920000669 heparin Polymers 0.000 description 1
229960002897 heparin Drugs 0.000 description 1
229920001477 hydrophilic polymer Polymers 0.000 description 1
230000002209 hydrophobic effect Effects 0.000 description 1
NBZBKCUXIYYUSX-UHFFFAOYSA-N iminodiacetic acid Chemical compound OC(=O)CNCC(O)=O NBZBKCUXIYYUSX-UHFFFAOYSA-N 0.000 description 1
150000002605 large molecules Chemical class 0.000 description 1
229920002521 macromolecule Polymers 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
235000019426 modified starch Nutrition 0.000 description 1
239000000178 monomer Substances 0.000 description 1
CERZMXAJYMMUDR-UHFFFAOYSA-N neuraminic acid Natural products NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO CERZMXAJYMMUDR-UHFFFAOYSA-N 0.000 description 1
229910052759 nickel Inorganic materials 0.000 description 1
102000039446 nucleic acids Human genes 0.000 description 1
108020004707 nucleic acids Proteins 0.000 description 1
150000007523 nucleic acids Chemical class 0.000 description 1
150000002924 oxiranes Chemical class 0.000 description 1
229960003540 oxyquinoline Drugs 0.000 description 1
RGSFGYAAUTVSQA-UHFFFAOYSA-N pentamethylene Natural products C1CCCC1 RGSFGYAAUTVSQA-UHFFFAOYSA-N 0.000 description 1
125000004817 pentamethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[*:1] 0.000 description 1
230000035699 permeability Effects 0.000 description 1
239000008363 phosphate buffer Substances 0.000 description 1
239000004033 plastic Substances 0.000 description 1
229920003023 plastic Polymers 0.000 description 1
229910052697 platinum Inorganic materials 0.000 description 1
BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Substances [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 1
-1 platinum metals Chemical class 0.000 description 1
238000006116 polymerization reaction Methods 0.000 description 1
239000000843 powder Substances 0.000 description 1
238000005086 pumping Methods 0.000 description 1
238000000746 purification Methods 0.000 description 1
MCJGNVYPOGVAJF-UHFFFAOYSA-N quinolin-8-ol Chemical compound C1=CN=C2C(O)=CC=CC2=C1 MCJGNVYPOGVAJF-UHFFFAOYSA-N 0.000 description 1
229910052761 rare earth metal Inorganic materials 0.000 description 1
150000002910 rare earth metals Chemical class 0.000 description 1
229920013730 reactive polymer Polymers 0.000 description 1
238000012552 review Methods 0.000 description 1
235000019515 salmon Nutrition 0.000 description 1
229910052709 silver Inorganic materials 0.000 description 1
239000004332 silver Substances 0.000 description 1
229910000033 sodium borohydride Inorganic materials 0.000 description 1
239000012279 sodium borohydride Substances 0.000 description 1
229910000029 sodium carbonate Inorganic materials 0.000 description 1
235000017550 sodium carbonate Nutrition 0.000 description 1
238000000527 sonication Methods 0.000 description 1
239000011593 sulfur Substances 0.000 description 1
229910052717 sulfur Inorganic materials 0.000 description 1
239000002344 surface layer Substances 0.000 description 1
239000000725 suspension Substances 0.000 description 1
229910052716 thallium Inorganic materials 0.000 description 1
BKVIYDNLLOSFOA-UHFFFAOYSA-N thallium Chemical compound [Tl] BKVIYDNLLOSFOA-UHFFFAOYSA-N 0.000 description 1
150000003568 thioethers Chemical class 0.000 description 1
230000007704 transition Effects 0.000 description 1
JFALSRSLKYAFGM-UHFFFAOYSA-N uranium(0) Chemical compound [U] JFALSRSLKYAFGM-UHFFFAOYSA-N 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
229910052725 zinc Inorganic materials 0.000 description 1
239000011701 zinc Substances 0.000 description 1
229910052726 zirconium Inorganic materials 0.000 description 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
- B01J20/28009—Magnetic properties
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
- B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3265—Non-macromolecular compounds with an organic functional group containing a metal, e.g. a metal affinity ligand
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/327—Polymers obtained by reactions involving only carbon to carbon unsaturated bonds
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
- B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
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- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
- Y10T428/2998—Coated including synthetic resin or polymer
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31725—Of polyamide
- Y10T428/31768—Natural source-type polyamide [e.g., casein, gelatin, etc.]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31855—Of addition polymer from unsaturated monomers
- Y10T428/31935—Ester, halide or nitrile of addition polymer
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31971—Of carbohydrate

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Chemical & Material Sciences (AREA)
Analytical Chemistry (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

SE8405241A 1984-10-19 1984-10-19 Polymerbelagda partiklar med immobiliserade metalljoner pa sin yta jemte forfarande for framstellning derav SE454885B (sv)

Priority Applications (5)

Application Number	Priority Date	Filing Date	Title
SE8405241A SE454885B (sv)	1984-10-19	1984-10-19	Polymerbelagda partiklar med immobiliserade metalljoner pa sin yta jemte forfarande for framstellning derav
DE8585850315T DE3583373D1 (de)	1984-10-19	1985-10-08	Metalloberflaeche mit polymerueberzug.
EP85850315A EP0179039B1 (de)	1984-10-19	1985-10-08	Metalloberfläche mit Polymerüberzug
US06/786,857 US4677027A (en)	1984-10-19	1985-10-11	Polymer coated particles having immobilized metal ions on the surfaces thereof
JP60234380A JPS61118398A (ja)	1984-10-19	1985-10-19	生体高分子の吸着剤およびその製造方法

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE8405241A SE454885B (sv)	1984-10-19	1984-10-19	Polymerbelagda partiklar med immobiliserade metalljoner pa sin yta jemte forfarande for framstellning derav

Publications (3)

Publication Number	Publication Date
SE8405241D0 SE8405241D0 (sv)	1984-10-19
SE8405241L SE8405241L (sv)	1986-04-20
SE454885B true SE454885B (sv)	1988-06-06

Family

ID=20357420

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8405241A SE454885B (sv)	1984-10-19	1984-10-19	Polymerbelagda partiklar med immobiliserade metalljoner pa sin yta jemte forfarande for framstellning derav

Country Status (5)

Country	Link
US (1)	US4677027A (de)
EP (1)	EP0179039B1 (de)
JP (1)	JPS61118398A (de)
DE (1)	DE3583373D1 (de)
SE (1)	SE454885B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
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WO1990011128A1 (en) *	1989-03-22	1990-10-04	Vinten Joergen C Aa	Polymer-coated noble metal particles and a method for their preparation

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US4888248A (en) *	1986-07-01	1989-12-19	Hidefumi Hirai	Colloidal metal dispersion, and a colloidal metal complex
US6552170B1 (en)	1990-04-06	2003-04-22	Amgen Inc.	PEGylation reagents and compounds formed therewith
US5521287A (en) *	1992-05-20	1996-05-28	The Green Cross Corporation	Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5440018A (en) *	1992-05-20	1995-08-08	The Green Cross Corporation	Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5446090A (en) *	1993-11-12	1995-08-29	Shearwater Polymers, Inc.	Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules
DE4428851C2 (de) *	1994-08-04	2000-05-04	Diagnostikforschung Inst	Eisen enthaltende Nanopartikel, ihre Herstellung und Anwendung in der Diagnostik und Therapie
ES2288760T3 (es)	1996-04-25	2008-01-16	Bioarray Solutions Ltd.	Ensamblaje electrocinetico controlado por luz de particulas proximas a superficies.
TW555765B (en)	1996-07-09	2003-10-01	Amgen Inc	Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
US6660843B1 (en) *	1998-10-23	2003-12-09	Amgen Inc.	Modified peptides as therapeutic agents
US6623655B1 (en) *	2000-04-24	2003-09-23	Sigma-Aldrich Co.	Metal chelating compositions
US9709559B2 (en)	2000-06-21	2017-07-18	Bioarray Solutions, Ltd.	Multianalyte molecular analysis using application-specific random particle arrays
US7262063B2 (en)	2001-06-21	2007-08-28	Bio Array Solutions, Ltd.	Directed assembly of functional heterostructures
KR20040068122A (ko)	2001-10-15	2004-07-30	바이오어레이 솔루션스 리미티드	공동 검색과 효소-매개된 탐지에 의한 다형성 좌위의 다중분석
AU2003298655A1 (en)	2002-11-15	2004-06-15	Bioarray Solutions, Ltd.	Analysis, secure access to, and transmission of array images
DE10331439B3 (de)	2003-07-10	2005-02-03	Micromod Partikeltechnologie Gmbh	Magnetische Nanopartikel mit verbesserten Magneteigenschaften
JP2004298783A (ja) *	2003-03-31	2004-10-28	Kitakyushu Foundation For The Advancement Of Industry Science & Technology	化学物質分離膜及びその製造方法、並びに化学物質の検出方法及び化学物質検出装置
US7595279B2 (en)	2003-09-22	2009-09-29	Bioarray Solutions Ltd.	Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
EP1692298A4 (de)	2003-10-28	2008-08-13	Bioarray Solutions Ltd	Optimierung der genexpressionsanalyse unter verwendung immobilisierter fängersonden
AU2004286253A1 (en) *	2003-10-28	2005-05-12	Bioarray Solutions Ltd.	Gel-shell beads with adsorbed or bound biomolecules
CZ299349B6 (cs) *	2004-03-18	2008-06-25	Ústav Makromolekulární Chemie Akademie Ved Ceské Republiky	Magnetické cástice pokryté vybranými polysacharidy
US7848889B2 (en)	2004-08-02	2010-12-07	Bioarray Solutions, Ltd.	Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
US7964380B2 (en) *	2005-01-21	2011-06-21	Argylia Technologies	Nanoparticles for manipulation of biopolymers and methods of thereof
US20090208919A1 (en) *	2005-01-21	2009-08-20	Argylla Technologies, Llp	Particle matrix for storage of biomolecules
US8288169B2 (en) *	2005-01-21	2012-10-16	Argylla Technologies	Surface mediated self-assembly of nanoparticles
WO2006112771A1 (en)	2005-04-18	2006-10-26	Ge Healthcare Bio-Sciences Ab	Magnetic beads
DE102006036380A1 (de) *	2006-08-02	2008-02-07	Universität des Saarlandes	Verfahren zur Beeinflussung lebender Zellen durch Zell-Oberflächen-Wechselwirkung
BRPI0721148B8 (pt) *	2006-12-18	2021-05-25	Colorobbia Italiana Spa	nanopartículas magnéticas para aplicação em hipertermia, preparação destas e uso de construtos apresentando aplicação farmacológica
RU2367513C2 (ru)	2007-11-21	2009-09-20	Учреждение Российской Академии Наук Институт Биохимической Физики Им. Н.М. Эмануэля Ран (Ибхф Ран)	Способ получения полимерного покрытия на поверхности частиц
US9776137B2 (en) *	2008-11-12	2017-10-03	Board Of Regents, The University Of Texas System	Recovery of regenerant electrolyte
GB201301631D0 (en)	2013-01-30	2013-03-13	Ge Healthcare Ltd	Separation of substances using magnetic beads
JP2013226149A (ja) *	2013-06-10	2013-11-07	Universal Bio Research Co Ltd	生体関連物質の分離回収方法

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US3783101A (en) *	1972-02-17	1974-01-01	Corning Glass Works	Enzymes bound to carriers having a metal oxide surface layer
US3970518A (en) *	1975-07-01	1976-07-20	General Electric Company	Magnetic separation of biological particles
IL63220A (en) *	1981-07-01	1985-09-29	Yeda Res & Dev	Process for production of polyacrolein microspheres
SE8201972L (sv) *	1982-03-29	1983-09-30	Gambro Lundia Ab	Magnetiskt paverkbara kristalliserade kolhydrat sferer eller partiklar att anvendas tillsammans med bioadsorberande material
US4452773A (en) *	1982-04-05	1984-06-05	Canadian Patents And Development Limited	Magnetic iron-dextran microspheres
JPS5920357B2 (ja) *	1982-08-05	1984-05-12	工業技術院長	脂質の酵素分解法
US4508625A (en) *	1982-10-18	1985-04-02	Graham Marshall D	Magnetic separation using chelated magnetic ions
JPS59182804A (ja) *	1983-04-01	1984-10-17	Toray Ind Inc	反応性微粒子およびその製造法

1984
- 1984-10-19 SE SE8405241A patent/SE454885B/sv not_active IP Right Cessation
1985
- 1985-10-08 EP EP85850315A patent/EP0179039B1/de not_active Expired - Lifetime
- 1985-10-08 DE DE8585850315T patent/DE3583373D1/de not_active Expired - Lifetime
- 1985-10-11 US US06/786,857 patent/US4677027A/en not_active Expired - Fee Related
- 1985-10-19 JP JP60234380A patent/JPS61118398A/ja active Granted

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1990011128A1 (en) *	1989-03-22	1990-10-04	Vinten Joergen C Aa	Polymer-coated noble metal particles and a method for their preparation

Also Published As

Publication number	Publication date
EP0179039B1 (de)	1991-07-03
SE8405241L (sv)	1986-04-20
US4677027A (en)	1987-06-30
EP0179039A2 (de)	1986-04-23
JPH0225920B2 (de)	1990-06-06
EP0179039A3 (en)	1986-12-30
SE8405241D0 (sv)	1984-10-19
DE3583373D1 (de)	1991-08-08
JPS61118398A (ja)	1986-06-05

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SE454885B - Polymerbelagda partiklar med immobiliserade metalljoner pa sin yta jemte forfarande for framstellning derav - Google Patents

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Priority Applications (5)

Applications Claiming Priority (1)

Publications (3)

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ID=20357420

Family Applications (1)

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Cited By (1)

Families Citing this family (31)

Family Cites Families (8)

Cited By (1)

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