SE517528C2 - Datoriserad identifiering av normala och onormala dygnsmönster för kortisolutsöndring och testosteronnivåer från mänskliga salivprov - Google Patents
Datoriserad identifiering av normala och onormala dygnsmönster för kortisolutsöndring och testosteronnivåer från mänskliga salivprovInfo
- Publication number
- SE517528C2 SE517528C2 SE0004461A SE0004461A SE517528C2 SE 517528 C2 SE517528 C2 SE 517528C2 SE 0004461 A SE0004461 A SE 0004461A SE 0004461 A SE0004461 A SE 0004461A SE 517528 C2 SE517528 C2 SE 517528C2
- Authority
- SE
- Sweden
- Prior art keywords
- cortisol
- variable
- computer
- cort
- logic
- Prior art date
Links
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 title claims abstract description 114
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 title claims abstract description 74
- 229960000890 hydrocortisone Drugs 0.000 title claims abstract description 58
- 229960003604 testosterone Drugs 0.000 title claims abstract description 37
- 210000003296 saliva Anatomy 0.000 title claims abstract description 25
- 230000002159 abnormal effect Effects 0.000 title claims abstract description 15
- 230000028327 secretion Effects 0.000 title claims abstract description 13
- 230000004179 hypothalamic–pituitary–adrenal axis Effects 0.000 claims abstract description 44
- 238000000034 method Methods 0.000 claims abstract description 18
- 238000004422 calculation algorithm Methods 0.000 claims abstract description 6
- 238000000338 in vitro Methods 0.000 claims abstract 2
- 238000012360 testing method Methods 0.000 claims description 44
- 230000006870 function Effects 0.000 claims description 23
- 238000011156 evaluation Methods 0.000 claims description 19
- 238000004590 computer program Methods 0.000 claims description 18
- 230000015654 memory Effects 0.000 claims description 9
- 230000036541 health Effects 0.000 claims description 5
- 230000008859 change Effects 0.000 claims description 3
- 230000004044 response Effects 0.000 claims description 3
- 230000000295 complement effect Effects 0.000 claims description 2
- 238000010340 saliva test Methods 0.000 claims description 2
- 241001550224 Apha Species 0.000 claims 1
- 230000002238 attenuated effect Effects 0.000 claims 1
- 230000002542 deteriorative effect Effects 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 238000005259 measurement Methods 0.000 description 24
- 238000004458 analytical method Methods 0.000 description 9
- 230000008901 benefit Effects 0.000 description 4
- 239000011159 matrix material Substances 0.000 description 4
- 210000002966 serum Anatomy 0.000 description 4
- 208000024172 Cardiovascular disease Diseases 0.000 description 3
- 206010022489 Insulin Resistance Diseases 0.000 description 3
- 230000002060 circadian Effects 0.000 description 3
- 230000002354 daily effect Effects 0.000 description 3
- 229960003957 dexamethasone Drugs 0.000 description 3
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 208000019622 heart disease Diseases 0.000 description 3
- 229940088597 hormone Drugs 0.000 description 3
- 239000005556 hormone Substances 0.000 description 3
- 230000002503 metabolic effect Effects 0.000 description 3
- 238000010998 test method Methods 0.000 description 3
- 208000001072 type 2 diabetes mellitus Diseases 0.000 description 3
- 230000005856 abnormality Effects 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 238000004364 calculation method Methods 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 230000000875 corresponding effect Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 238000012552 review Methods 0.000 description 2
- 238000007619 statistical method Methods 0.000 description 2
- 230000003936 working memory Effects 0.000 description 2
- 208000004611 Abdominal Obesity Diseases 0.000 description 1
- 235000011297 Brassica napobrassica Nutrition 0.000 description 1
- 206010065941 Central obesity Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 208000001145 Metabolic Syndrome Diseases 0.000 description 1
- 241000473945 Theria <moth genus> Species 0.000 description 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 description 1
- 210000004404 adrenal cortex Anatomy 0.000 description 1
- 210000004100 adrenal gland Anatomy 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- JQQZVABVKIDEFR-UHFFFAOYSA-J bumadizone calcium hemihydrate Chemical compound O.[Ca+2].[Ca+2].C=1C=CC=CC=1N(C(=O)C(C([O-])=O)CCCC)NC1=CC=CC=C1.C=1C=CC=CC=1N(C(=O)C(C([O-])=O)CCCC)NC1=CC=CC=C1.C=1C=CC=CC=1N(C(=O)C(C([O-])=O)CCCC)NC1=CC=CC=C1.C=1C=CC=CC=1N(C(=O)C(C([O-])=O)CCCC)NC1=CC=CC=C1 JQQZVABVKIDEFR-UHFFFAOYSA-J 0.000 description 1
- 230000027288 circadian rhythm Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 230000004720 fertilization Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000010230 functional analysis Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 210000002149 gonad Anatomy 0.000 description 1
- 239000003163 gonadal steroid hormone Substances 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Substances N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 1
- 238000013507 mapping Methods 0.000 description 1
- 230000006371 metabolic abnormality Effects 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000000955 neuroendocrine Effects 0.000 description 1
- 238000009806 oophorectomy Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 230000036299 sexual function Effects 0.000 description 1
- 239000008279 sol Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
- G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Primary Health Care (AREA)
- Public Health (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Eye Examination Apparatus (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0004461A SE517528C2 (sv) | 2000-12-04 | 2000-12-04 | Datoriserad identifiering av normala och onormala dygnsmönster för kortisolutsöndring och testosteronnivåer från mänskliga salivprov |
| DE60130020T DE60130020T2 (de) | 2000-12-04 | 2001-12-04 | Computerisierte identifizierung normaler und abnormaler diurnaler cortisolsekretionsmuster und von testosteronspiegeln aus menschlichen speichelproben |
| PCT/SE2001/002670 WO2002046771A1 (en) | 2000-12-04 | 2001-12-04 | Computerized identification of normal and abnormal diurnal cortisol secretion patterns and levels of testosterone from human saliva samples |
| JP2002548457A JP2004515765A (ja) | 2000-12-04 | 2001-12-04 | 人間の唾液標本からの一日の正常および異常コルチゾール分泌パターンとテストステロン水準のコンピュータ化識別 |
| AT01999819T ATE370417T1 (de) | 2000-12-04 | 2001-12-04 | Computerisierte identifizierung normaler und abnormaler diurnaler cortisolsekretionsmuster und von testosteronspiegeln aus menschlichen speichelproben |
| EP01999819A EP1340089B1 (de) | 2000-12-04 | 2001-12-04 | Computerisierte identifizierung normaler und abnormaler diurnaler cortisolsekretionsmuster und von testosteronspiegeln aus menschlichen speichelproben |
| US10/448,379 US7805396B2 (en) | 2000-12-04 | 2003-05-30 | Computerized identification of normal and abnormal diurnal cortisol secretion patterns and levels of testosterone from human saliva samples |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0004461A SE517528C2 (sv) | 2000-12-04 | 2000-12-04 | Datoriserad identifiering av normala och onormala dygnsmönster för kortisolutsöndring och testosteronnivåer från mänskliga salivprov |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE0004461D0 SE0004461D0 (sv) | 2000-12-04 |
| SE0004461L SE0004461L (sv) | 2002-06-05 |
| SE517528C2 true SE517528C2 (sv) | 2002-06-18 |
Family
ID=20282077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0004461A SE517528C2 (sv) | 2000-12-04 | 2000-12-04 | Datoriserad identifiering av normala och onormala dygnsmönster för kortisolutsöndring och testosteronnivåer från mänskliga salivprov |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7805396B2 (de) |
| EP (1) | EP1340089B1 (de) |
| JP (1) | JP2004515765A (de) |
| AT (1) | ATE370417T1 (de) |
| DE (1) | DE60130020T2 (de) |
| SE (1) | SE517528C2 (de) |
| WO (1) | WO2002046771A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060129590A1 (en) * | 2004-12-10 | 2006-06-15 | Aoki-Rice Companies | Method and medium for managing data |
| AU2008251588B2 (en) | 2007-05-10 | 2013-10-31 | Advanced Breath Diagnostics, Llc | Methods and systems for assessing gastric emptying |
| KR101029251B1 (ko) | 2009-06-18 | 2011-04-18 | 전남대학교산학협력단 | 타액내 코티졸 측정을 통한 코티졸의 일주기리듬 평가 지표 및 방법 |
| US11195057B2 (en) | 2014-03-18 | 2021-12-07 | Z Advanced Computing, Inc. | System and method for extremely efficient image and pattern recognition and artificial intelligence platform |
| US9916538B2 (en) | 2012-09-15 | 2018-03-13 | Z Advanced Computing, Inc. | Method and system for feature detection |
| US11914674B2 (en) | 2011-09-24 | 2024-02-27 | Z Advanced Computing, Inc. | System and method for extremely efficient image and pattern recognition and artificial intelligence platform |
| US11074495B2 (en) | 2013-02-28 | 2021-07-27 | Z Advanced Computing, Inc. (Zac) | System and method for extremely efficient image and pattern recognition and artificial intelligence platform |
| US8311973B1 (en) | 2011-09-24 | 2012-11-13 | Zadeh Lotfi A | Methods and systems for applications for Z-numbers |
| US8873813B2 (en) | 2012-09-17 | 2014-10-28 | Z Advanced Computing, Inc. | Application of Z-webs and Z-factors to analytics, search engine, learning, recognition, natural language, and other utilities |
| KR101444235B1 (ko) * | 2012-07-17 | 2014-09-26 | 주식회사 피코팜 | 뇌하수체 부신축 기능의 상관관계를 이용하는 crps―1 질환 진단 방법 |
| US10772534B2 (en) | 2013-03-13 | 2020-09-15 | Advanced Breath Diagnostics, Llc | Single-point gastric emptying breath tests |
| KR102404986B1 (ko) * | 2022-01-20 | 2022-06-07 | (주) 마인즈에이아이 | 남성 갱년기 진단을 위한 정보를 제공하는 방법 및 이의 용도 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5788640A (en) * | 1995-10-26 | 1998-08-04 | Peters; Robert Mitchell | System and method for performing fuzzy cluster classification of stress tests |
| EP1027459A1 (de) * | 1997-07-14 | 2000-08-16 | Abbott Laboratories | Telemedizin |
| JPH1138004A (ja) * | 1997-07-16 | 1999-02-12 | Pola Chem Ind Inc | ストレスの定量法 |
| JP3108765B2 (ja) * | 1999-03-24 | 2000-11-13 | 工業技術院長 | 慢性ストレス判定方法及びその装置、記録媒体、判定シート |
-
2000
- 2000-12-04 SE SE0004461A patent/SE517528C2/sv not_active IP Right Cessation
-
2001
- 2001-12-04 DE DE60130020T patent/DE60130020T2/de not_active Expired - Lifetime
- 2001-12-04 WO PCT/SE2001/002670 patent/WO2002046771A1/en not_active Ceased
- 2001-12-04 EP EP01999819A patent/EP1340089B1/de not_active Expired - Lifetime
- 2001-12-04 JP JP2002548457A patent/JP2004515765A/ja active Pending
- 2001-12-04 AT AT01999819T patent/ATE370417T1/de not_active IP Right Cessation
-
2003
- 2003-05-30 US US10/448,379 patent/US7805396B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60130020T2 (de) | 2008-05-08 |
| EP1340089A1 (de) | 2003-09-03 |
| US20100241606A9 (en) | 2010-09-23 |
| US7805396B2 (en) | 2010-09-28 |
| SE0004461L (sv) | 2002-06-05 |
| EP1340089B1 (de) | 2007-08-15 |
| ATE370417T1 (de) | 2007-09-15 |
| SE0004461D0 (sv) | 2000-12-04 |
| WO2002046771A1 (en) | 2002-06-13 |
| JP2004515765A (ja) | 2004-05-27 |
| DE60130020D1 (de) | 2007-09-27 |
| US20040039719A1 (en) | 2004-02-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Grosvenor et al. | Autism diagnosis among US children and adults, 2011-2022 | |
| Young et al. | Reliability, construct validity, and responsiveness of the neck disability index and numeric pain rating scale in patients with mechanical neck pain without upper extremity symptoms | |
| Fritz et al. | Handgrip strength as a means of monitoring progression of cognitive decline–a scoping review | |
| Tengs et al. | A meta-analysis of utility estimates for HIV/AIDS | |
| Scheidt-Nave et al. | German health interview and examination survey for adults (DEGS)-design, objectives and implementation of the first data collection wave | |
| Minet et al. | Mediating the effect of self-care management intervention in type 2 diabetes: a meta-analysis of 47 randomised controlled trials | |
| US20120101846A1 (en) | Computer-Implemented Method For Displaying Patient-Related Diagnoses Of Chronic Illnesses | |
| US8548827B2 (en) | Computer-implemented method for medical diagnosis support | |
| JP5317496B2 (ja) | 健康疾患管理支援装置及び方法、並びに医用ネットワークシステム | |
| Widyana et al. | Psychometric properties of internet-administered version of depression, anxiety and stress scales (DASS-42) in sample Indonesian adult | |
| US7805396B2 (en) | Computerized identification of normal and abnormal diurnal cortisol secretion patterns and levels of testosterone from human saliva samples | |
| de Souza de Silva et al. | Association between cardiorespiratory fitness, obesity, and health care costs: the veterans exercise testing study | |
| Hjelholt et al. | The interaction effect between previous stroke and hip fracture on postoperative mortality: a nationwide cohort study | |
| Krops et al. | Reliability of translation of the RAND 36-item health survey in a post-rehabilitation population | |
| Sundaram et al. | Health-related quality of life and quality of life in type 2 diabetes: relationships in a cross-sectional study | |
| Deo et al. | Design and development of a web-based application for diabetes patient data management | |
| Yang et al. | Heterogeneity of Fatigue in Patients with Chronic Heart Failure: Latent Categories and Influencing Factors | |
| Yarris et al. | How accurately can emergency department providers estimate patient satisfaction? | |
| US10973467B2 (en) | Method and system for automated diagnostics of none-infectious illnesses | |
| Yen et al. | A nationwide population cohort study: irritable bowel syndrome is a risk factor of osteoporosis | |
| Duan et al. | A scoping review of cross-sectional studies on traditional Chinese medicine | |
| Joshi et al. | Quality of nutrition related information on the internet for osteoporosis patients: a critical review | |
| Berlowitz et al. | Ambulatory care casemix measures | |
| Marshall | Estimating the value of information in strategies for identifying patients at high risk of cardiovascular disease | |
| Miao et al. | Sedentary behavior from television watching elevates GlycA levels: a bidirectional Mendelian randomization study |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |