SE520046C2 - Förfarande för att mäta växelverkan mellan en målmolekyl och en receptormolekyl med piezoelektrisk kristallmikrovåg - Google Patents

Förfarande för att mäta växelverkan mellan en målmolekyl och en receptormolekyl med piezoelektrisk kristallmikrovåg

Info

Publication number
SE520046C2
SE520046C2 SE9704354A SE9704354A SE520046C2 SE 520046 C2 SE520046 C2 SE 520046C2 SE 9704354 A SE9704354 A SE 9704354A SE 9704354 A SE9704354 A SE 9704354A SE 520046 C2 SE520046 C2 SE 520046C2
Authority
SE
Sweden
Prior art keywords
molecule
dissipation
target molecule
receptor molecule
crystal
Prior art date
Application number
SE9704354A
Other languages
English (en)
Swedish (sv)
Other versions
SE9704354D0 (sv
SE9704354L (sv
Inventor
Fredrik Hoeoek
Original Assignee
Sense Ab Q
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sense Ab Q filed Critical Sense Ab Q
Priority to SE9704354A priority Critical patent/SE520046C2/sv
Publication of SE9704354D0 publication Critical patent/SE9704354D0/xx
Priority to AT98957299T priority patent/ATE317547T1/de
Priority to EP98957299A priority patent/EP1034430B1/de
Priority to DE69833450T priority patent/DE69833450T2/de
Priority to CA002311398A priority patent/CA2311398A1/en
Priority to JP2000524667A priority patent/JP2001526392A/ja
Priority to CN98812572.2A priority patent/CN1195985C/zh
Priority to AU13588/99A priority patent/AU752190B2/en
Priority to PCT/SE1998/002129 priority patent/WO1999030159A1/en
Publication of SE9704354L publication Critical patent/SE9704354L/xx
Publication of SE520046C2 publication Critical patent/SE520046C2/sv

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/02—Analysing fluids
    • G01N29/036—Analysing fluids by measuring frequency or resonance of acoustic waves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/025—Change of phase or condition
    • G01N2291/0256—Adsorption, desorption, surface mass change, e.g. on biosensors
    • G01N2291/0257—Adsorption, desorption, surface mass change, e.g. on biosensors with a layer containing at least one organic compound
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/03—Herpetoviridae, e.g. pseudorabies virus
    • G01N2333/035—Herpes simplex virus I or II

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Acoustics & Sound (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
SE9704354A 1997-11-24 1997-11-24 Förfarande för att mäta växelverkan mellan en målmolekyl och en receptormolekyl med piezoelektrisk kristallmikrovåg SE520046C2 (sv)

Priority Applications (9)

Application Number Priority Date Filing Date Title
SE9704354A SE520046C2 (sv) 1997-11-24 1997-11-24 Förfarande för att mäta växelverkan mellan en målmolekyl och en receptormolekyl med piezoelektrisk kristallmikrovåg
PCT/SE1998/002129 WO1999030159A1 (en) 1997-11-24 1998-11-24 Sensor for detecting biological matter
CA002311398A CA2311398A1 (en) 1997-11-24 1998-11-24 Sensor for detecting biological matter
EP98957299A EP1034430B1 (de) 1997-11-24 1998-11-24 Sensor zur erfassung von biologischem komplex
DE69833450T DE69833450T2 (de) 1997-11-24 1998-11-24 Sensor zur erfassung von biologischem komplex
AT98957299T ATE317547T1 (de) 1997-11-24 1998-11-24 Sensor zur erfassung von biologischem komplex
JP2000524667A JP2001526392A (ja) 1997-11-24 1998-11-24 生物学的物質を検出するためのセンサー
CN98812572.2A CN1195985C (zh) 1997-11-24 1998-11-24 用来检测生物物质的传感器
AU13588/99A AU752190B2 (en) 1997-11-24 1998-11-24 Sensor for detecting biological matter

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9704354A SE520046C2 (sv) 1997-11-24 1997-11-24 Förfarande för att mäta växelverkan mellan en målmolekyl och en receptormolekyl med piezoelektrisk kristallmikrovåg

Publications (3)

Publication Number Publication Date
SE9704354D0 SE9704354D0 (sv) 1997-11-24
SE9704354L SE9704354L (sv) 1999-05-25
SE520046C2 true SE520046C2 (sv) 2003-05-13

Family

ID=20409135

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9704354A SE520046C2 (sv) 1997-11-24 1997-11-24 Förfarande för att mäta växelverkan mellan en målmolekyl och en receptormolekyl med piezoelektrisk kristallmikrovåg

Country Status (9)

Country Link
EP (1) EP1034430B1 (de)
JP (1) JP2001526392A (de)
CN (1) CN1195985C (de)
AT (1) ATE317547T1 (de)
AU (1) AU752190B2 (de)
CA (1) CA2311398A1 (de)
DE (1) DE69833450T2 (de)
SE (1) SE520046C2 (de)
WO (1) WO1999030159A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001001121A1 (en) * 1999-06-29 2001-01-04 Ut-Battelle, Llc Multi-modal analysis of micromechanical structures for sensing applications
JP3376417B2 (ja) 2000-04-20 2003-02-10 独立行政法人産業技術総合研究所 高周波数水晶振動子を用いた超微量質量の検出装置用校正方法
DE10050632A1 (de) * 2000-10-12 2002-04-18 Stiftung Caesar Verfahren zum Nachweis biologischer Moleküle
US20070251321A1 (en) * 2003-11-13 2007-11-01 Holger Fritze Sensor, Sensor Arrangement and Measuring Method
JP4772563B2 (ja) * 2006-03-31 2011-09-14 日本製紙株式会社 異物の沈積度合を測定する方法
JP4820999B2 (ja) * 2006-05-10 2011-11-24 国立大学法人神戸大学 標的分子のセンサー素子およびその製造方法
JP2010510247A (ja) 2006-11-21 2010-04-02 アプライド バイオシステムズ インコーポレイテッド 酸化物層上に不動態化表面を形成するための中間体および方法およびこれにより製造される製品
GB0705088D0 (en) * 2007-03-16 2007-04-25 Akubio Ltd Improvements in or relating to detection and/or characterisation of aggregates
US8173198B2 (en) 2008-07-23 2012-05-08 Life Technologies Corporation Deposition of metal oxides onto surfaces as an immobilization vehicle for carboxylated or phophated particles or polymers
CN102356315A (zh) * 2009-03-20 2012-02-15 安塔纳公司 含有在其表面固定的细胞的质量敏感性传感器及利用所述传感器检测配体结合的方法
ES2333088B2 (es) * 2009-06-23 2011-02-07 Universidad Politecnica De Valencia Metodo y dispositivo de nanogravimetria en medios fluidos basado en resonadores piezoelectricos.
GB2473635A (en) 2009-09-18 2011-03-23 Cambridge Entpr Ltd Detecting concentration of target species
FR2968766B1 (fr) 2010-12-10 2016-12-09 Univ De Tech De Troyes Systeme de procede de detection d'especes biologiques ou chimiques bases sur un qcm structure
CN102393342B (zh) * 2011-10-25 2013-03-27 中国科学院苏州纳米技术与纳米仿生研究所 一种利用石英晶体微天平筛选端粒酶抑制剂的方法
CN102692513A (zh) * 2012-06-26 2012-09-26 长沙理工大学 致癌基因C-myc重组蛋白的压电免疫传感芯片及装置
WO2017053481A1 (en) * 2015-09-21 2017-03-30 Rutgers, The State University Of New Jersey Magnesium zinc oxide nanostructure modified biosensor and monitoring of response of cell population to an agent using the same
CN106404915B (zh) * 2016-08-29 2019-02-19 湖南农业大学 一种细胞牵引力的实时与定量测定方法
JP6951933B2 (ja) * 2017-10-10 2021-10-20 花王株式会社 シリコンウェーハ用仕上げ研磨液組成物
WO2020090944A1 (ja) * 2018-10-30 2020-05-07 京セラ株式会社 測定装置および測定方法
GB2629413A (en) * 2023-04-27 2024-10-30 The Univ Of Durham Method and apparatus for detecting a target in a complex fluid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846708A (en) * 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
SE504199C2 (sv) * 1995-05-04 1996-12-02 Bengt Kasemo Anordning vid mätning av resonansfrekvens och/eller dissipationsfaktor hos en piezoelektrisk kristallmikrovåg

Also Published As

Publication number Publication date
ATE317547T1 (de) 2006-02-15
JP2001526392A (ja) 2001-12-18
EP1034430A1 (de) 2000-09-13
AU752190B2 (en) 2002-09-12
CA2311398A1 (en) 1999-06-17
SE9704354D0 (sv) 1997-11-24
CN1195985C (zh) 2005-04-06
AU1358899A (en) 1999-06-28
EP1034430B1 (de) 2006-02-08
SE9704354L (sv) 1999-05-25
DE69833450T2 (de) 2006-11-02
WO1999030159A1 (en) 1999-06-17
DE69833450D1 (de) 2006-04-20
CN1283270A (zh) 2001-02-07

Similar Documents

Publication Publication Date Title
SE520046C2 (sv) Förfarande för att mäta växelverkan mellan en målmolekyl och en receptormolekyl med piezoelektrisk kristallmikrovåg
Bunde et al. Piezoelectric quartz crystal biosensors
US7914740B2 (en) Biosensor utilizing a resonator having a functionalized surface
EP0295965B1 (de) Auf einem Oszillator basiertes Verfahren zum Detektieren eines Mitgliedes eines spezifischen Bindungspaares
US10571437B2 (en) Temperature compensation and operational configuration for bulk acoustic wave resonator devices
US7811831B2 (en) Systems and methods for molecular recognition
de Vasconcelos et al. Potential of a simplified measurement scheme and device structure for a low cost label-free point-of-care capacitive biosensor
US20220349857A1 (en) Resonator for detecting single molecule binding
US11346814B2 (en) Resonator for the detection of a mass analyte and method for operation of the resonator
Yang et al. Biomolecular stiffness detection based on positive frequency shift of CMOS compatible gigahertz solidly mounted resonators
Saffari et al. Label-Free Real-Time Detection of HBsAg Using a QCM Immunosensor.
JP3631373B2 (ja) 免疫分析法および免疫分析装置
Pohanka Piezoelectric immunosensor for the determination of immunoglobulin G
Yao et al. A novel piezoelectric quartz micro-array immunosensor for detection of immunoglobulinE
Xu et al. Mechanical vibration-assisted modulation of E. coli binding to poly-l-lysine coated biosensor surface
Xiao et al. Lead magnesium niobate-lead titanate piezoelectric immunosensors
Hedley et al. A generic sensor for ultra low analyte concentration detection
Ayela et al. Piezoelectric micromembranes for the fabrication of a diagnostic chip based on the real-time monitoring of antigen-antibody interactions
Mascini et al. Immunosensors based on piezoelectric crystal device
Maraldo Detection of proteins and pathogens in complex matrices using a novel cantilever design
HK1093553B (en) Biosensor utilizing a resonator having a functionalized surface