SE7409203L - - Google Patents
Info
- Publication number
- SE7409203L SE7409203L SE7409203A SE7409203A SE7409203L SE 7409203 L SE7409203 L SE 7409203L SE 7409203 A SE7409203 A SE 7409203A SE 7409203 A SE7409203 A SE 7409203A SE 7409203 L SE7409203 L SE 7409203L
- Authority
- SE
- Sweden
- Prior art keywords
- capsules
- july
- contain
- glycoside
- cardiotonic
- Prior art date
Links
- 239000002775 capsule Substances 0.000 abstract 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- 229940097217 cardiac glycoside Drugs 0.000 abstract 2
- 239000002368 cardiac glycoside Substances 0.000 abstract 2
- 230000003177 cardiotonic effect Effects 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- LPMXVESGRSUGHW-HBYQJFLCSA-N ouabain Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1C[C@@]2(O)CC[C@H]3[C@@]4(O)CC[C@H](C=5COC(=O)C=5)[C@@]4(C)C[C@@H](O)[C@@H]3[C@@]2(CO)[C@H](O)C1 LPMXVESGRSUGHW-HBYQJFLCSA-N 0.000 abstract 2
- 229930002534 steroid glycoside Natural products 0.000 abstract 2
- WDJUZGPOPHTGOT-OAXVISGBSA-N Digitoxin Natural products O([C@H]1[C@@H](C)O[C@@H](O[C@@H]2C[C@@H]3[C@@](C)([C@@H]4[C@H]([C@]5(O)[C@@](C)([C@H](C6=CC(=O)OC6)CC5)CC4)CC3)CC2)C[C@H]1O)[C@H]1O[C@@H](C)[C@H](O[C@H]2O[C@@H](C)[C@@H](O)[C@@H](O)C2)[C@@H](O)C1 WDJUZGPOPHTGOT-OAXVISGBSA-N 0.000 abstract 1
- LTMHDMANZUZIPE-AMTYYWEZSA-N Digoxin Natural products O([C@H]1[C@H](C)O[C@H](O[C@@H]2C[C@@H]3[C@@](C)([C@@H]4[C@H]([C@]5(O)[C@](C)([C@H](O)C4)[C@H](C4=CC(=O)OC4)CC5)CC3)CC2)C[C@@H]1O)[C@H]1O[C@H](C)[C@@H](O[C@H]2O[C@@H](C)[C@H](O)[C@@H](O)C2)[C@@H](O)C1 LTMHDMANZUZIPE-AMTYYWEZSA-N 0.000 abstract 1
- 239000001828 Gelatine Substances 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229960000648 digitoxin Drugs 0.000 abstract 1
- WDJUZGPOPHTGOT-XUDUSOBPSA-N digitoxin Chemical compound C1[C@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)CC5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O WDJUZGPOPHTGOT-XUDUSOBPSA-N 0.000 abstract 1
- 229960005156 digoxin Drugs 0.000 abstract 1
- LTMHDMANZUZIPE-PUGKRICDSA-N digoxin Chemical compound C1[C@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)[C@H](O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O LTMHDMANZUZIPE-PUGKRICDSA-N 0.000 abstract 1
- LTMHDMANZUZIPE-UHFFFAOYSA-N digoxine Natural products C1C(O)C(O)C(C)OC1OC1C(C)OC(OC2C(OC(OC3CC4C(C5C(C6(CCC(C6(C)C(O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)CC2O)C)CC1O LTMHDMANZUZIPE-UHFFFAOYSA-N 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 229930182470 glycoside Natural products 0.000 abstract 1
- 150000002338 glycosides Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1481411 Cardiotonic capsules R P SCHERER Ltd 15 July 1974 [20 July 1973] 34804/73 Heading A5B Soft gelatine capsules contain a liquid cardiotonic composition comprising (a) a cardiac glycoside, (b) ethanol, (c) water, (d) propylene glycol and/or glycerine, and (e) a liquid polyethylene glycol. The glycoside (a) may be digitoxin or digoxin. The capsules may contain 50 to 300 micrograms of cardiac glycoside. The capsules may be compounded so that an accurate dose of the active ingredient is ensured.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB34804/73A GB1481411A (en) | 1973-07-20 | 1973-07-20 | Pharmaceutical compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7409203L true SE7409203L (en) | 1975-01-21 |
| SE405804B SE405804B (en) | 1979-01-08 |
Family
ID=10370134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7409203A SE405804B (en) | 1973-07-20 | 1974-07-15 | PROCEDURE FOR PREPARING A CARDIOTONIC DOSAGE UNIT FORM |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS5550927B2 (en) |
| AT (1) | AT342775B (en) |
| BE (1) | BE817757A (en) |
| CA (1) | CA1095411A (en) |
| DE (1) | DE2434849C2 (en) |
| DK (1) | DK137119B (en) |
| ES (1) | ES428443A1 (en) |
| FI (1) | FI63670C (en) |
| FR (1) | FR2237619B1 (en) |
| GB (1) | GB1481411A (en) |
| NL (1) | NL185824C (en) |
| SE (1) | SE405804B (en) |
| ZA (1) | ZA744488B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4198391A (en) | 1973-07-20 | 1980-04-15 | R. P. Scherer Ltd. | Pharmaceutical compositions |
| FR2261752B1 (en) * | 1974-02-22 | 1978-07-21 | Wellcome Found | |
| GB1508770A (en) * | 1974-04-01 | 1978-04-26 | Scherer Ltd R | Pharmaceutical compositions |
| GB1488259A (en) * | 1974-08-28 | 1977-10-12 | Scherer Corp R P | Method for increasing the bioavailability of digitalis cardiac glycosides |
| US4002718A (en) | 1974-10-16 | 1977-01-11 | Arnar-Stone Laboratories, Inc. | Gelatin-encapsulated digoxin solutions and method of preparing the same |
| US4067960A (en) | 1975-06-20 | 1978-01-10 | R. P. Scherer Limited | Pharmaceutical compositions containing cardiac glycoside |
| DE2805165A1 (en) * | 1977-02-09 | 1978-08-10 | Christiaens Sa A | MEDICINAL PRODUCT CONTAINING GITOXIN AND THE METHOD OF MANUFACTURING IT |
| JPS5625428U (en) * | 1979-08-03 | 1981-03-09 | ||
| US5141961A (en) * | 1991-06-27 | 1992-08-25 | Richrdson-Vicks Inc. | Process for solubilizing difficulty soluble pharmaceutical actives |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2298122A (en) * | 1941-01-27 | 1942-10-06 | United Drug Company | Digitalis capsule |
| US2860086A (en) * | 1955-02-04 | 1958-11-11 | Saul & Co | Stable solutions of pure cardioactive glycosides |
| US3531462A (en) * | 1967-05-19 | 1970-09-29 | Shionogi Seiyaku Kk | Carbonates of cardenolide tridigitoxosides and ester derivatives thereof |
| CA959759A (en) * | 1970-01-15 | 1974-12-24 | John J. Miskel | Method for absorption of drugs |
| SU432703A3 (en) * | 1971-08-24 | 1974-06-15 | Фридрих Боссерт, Вульф Фатер, Курт Бауер |
-
1973
- 1973-07-20 GB GB34804/73A patent/GB1481411A/en not_active Expired
-
1974
- 1974-07-12 ZA ZA00744488A patent/ZA744488B/en unknown
- 1974-07-15 SE SE7409203A patent/SE405804B/en not_active IP Right Cessation
- 1974-07-16 FI FI2164/74A patent/FI63670C/en active
- 1974-07-17 CA CA204,932A patent/CA1095411A/en not_active Expired
- 1974-07-17 BE BE146653A patent/BE817757A/en not_active IP Right Cessation
- 1974-07-18 DK DK387774AA patent/DK137119B/en not_active IP Right Cessation
- 1974-07-18 FR FR7425046A patent/FR2237619B1/fr not_active Expired
- 1974-07-19 DE DE2434849A patent/DE2434849C2/en not_active Expired
- 1974-07-19 ES ES428443A patent/ES428443A1/en not_active Expired
- 1974-07-19 NL NLAANVRAGE7409832,A patent/NL185824C/en active Search and Examination
- 1974-07-19 JP JP8308874A patent/JPS5550927B2/ja not_active Expired
- 1974-11-12 AT AT902574A patent/AT342775B/en active
Also Published As
| Publication number | Publication date |
|---|---|
| ATA902574A (en) | 1977-08-15 |
| DK137119C (en) | 1978-07-24 |
| FR2237619A1 (en) | 1975-02-14 |
| FR2237619B1 (en) | 1978-07-28 |
| CA1095411A (en) | 1981-02-10 |
| AU7132874A (en) | 1976-01-22 |
| SE405804B (en) | 1979-01-08 |
| FI63670B (en) | 1983-04-29 |
| ES428443A1 (en) | 1984-06-01 |
| JPS5550927B2 (en) | 1980-12-20 |
| FI216474A7 (en) | 1975-01-21 |
| JPS5094114A (en) | 1975-07-26 |
| NL7409832A (en) | 1975-01-22 |
| DE2434849C2 (en) | 1986-03-20 |
| DK387774A (en) | 1975-03-10 |
| FI63670C (en) | 1983-08-10 |
| ZA744488B (en) | 1975-07-30 |
| NL185824C (en) | 1990-08-01 |
| GB1481411A (en) | 1977-07-27 |
| DE2434849A1 (en) | 1975-02-06 |
| BE817757A (en) | 1974-11-18 |
| DK137119B (en) | 1978-01-23 |
| AT342775B (en) | 1978-04-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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