SE7600585L - Forfarande for framstellning av 7-aminocefalosporansyraderivat - Google Patents

Forfarande for framstellning av 7-aminocefalosporansyraderivat

Info

Publication number: SE7600585L
Authority: SE; Sweden
Prior art keywords: acid derivatives; salt; general formula; image; hydrogen
Prior art date: 1975-01-22

Application number

SE7600585A

Other languages

Unknown language ( )

English (en)

Other versions

SE427184B (sv

Inventor

N Suzuki

T Sowa

M Murakami

Original Assignee

Asahi Chemical Ind

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-01-22

Filing date

1976-01-21

Publication date

1976-07-23

1975-01-22 Priority claimed from JP863675A external-priority patent/JPS5186490A/ja

1975-07-09 Priority claimed from JP8357575A external-priority patent/JPS5929599B2/ja

1975-07-09 Priority claimed from JP8357475A external-priority patent/JPS527986A/ja

1976-01-21 Application filed by Asahi Chemical Ind filed Critical Asahi Chemical Ind

1976-07-23 Publication of SE7600585L publication Critical patent/SE7600585L/sv

1983-03-14 Publication of SE427184B publication Critical patent/SE427184B/sv

Links

239000002253 acid Substances 0.000 title 1
MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 4
150000003839 salts Chemical class 0.000 abstract 3
HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical class S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
238000006243 chemical reaction Methods 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical group CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
229930186147 Cephalosporin Natural products 0.000 abstract 1
HOKIDJSKDBPKTQ-GLXFQSAKSA-N Cephalosporin C Natural products S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001408 amides Chemical group 0.000 abstract 1
239000003242 anti bacterial agent Substances 0.000 abstract 1
229940088710 antibiotic agent Drugs 0.000 abstract 1
125000003435 aroyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
229940124587 cephalosporin Drugs 0.000 abstract 1
HOKIDJSKDBPKTQ-GLXFQSAKSA-M cephalosporin C(1-) Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H]([NH3+])C([O-])=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-M 0.000 abstract 1
150000001780 cephalosporins Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000000269 nucleophilic effect Effects 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
239000007858 starting material Substances 0.000 abstract 1
DHCDFWKWKRSZHF-UHFFFAOYSA-N sulfurothioic S-acid Chemical compound OS(O)(=O)=S DHCDFWKWKRSZHF-UHFFFAOYSA-N 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)

SE7600585A 1975-01-22 1976-01-21 Forfarande for framstellning av 7-aminocefalosporansyraderivat SE427184B (sv)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP863675A JPS5186490A (ja)	1975-01-22	1975-01-22	Sefuarosuhorinkagobutsuno seiho
JP8357575A JPS5929599B2 (ja)	1975-07-09	1975-07-09	７−アミノセフアロスポラン酸誘導体の製造法
JP8357475A JPS527986A (en)	1975-07-09	1975-07-09	Process for preparing 7-aminocephalosporanic acid derivatives

Publications (2)

Publication Number	Publication Date
SE7600585L true SE7600585L (sv)	1976-07-23
SE427184B SE427184B (sv)	1983-03-14

Family

ID=27278114

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7600585A SE427184B (sv)	1975-01-22	1976-01-21	Forfarande for framstellning av 7-aminocefalosporansyraderivat

Country Status (12)

Country	Link
US (1)	US4079180A (sv)
BE (1)	BE837766A (sv)
CA (1)	CA1069120A (sv)
CH (1)	CH621124A5 (sv)
DE (2)	DE2659857A1 (sv)
DK (1)	DK153554C (sv)
FR (1)	FR2298552A1 (sv)
GB (1)	GB1494452A (sv)
HU (1)	HU171208B (sv)
IT (1)	IT1053405B (sv)
NL (1)	NL163789C (sv)
SE (1)	SE427184B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4175185A (en) *	1976-05-19	1979-11-20	Meiji Seika Kaisha Ltd.	Process for preparing cephalosporanic acid derivatives
ES2079442T3 (es) *	1989-07-19	1996-01-16	Lilly Co Eli	Oxidacion enzimatica mejorada de cef c a acido glutaril-7-amino-cefalosporanico.
EP0720611A1 (en) *	1994-07-22	1996-07-10	Antibioticos S.P.A.	Glutaryl 7-aca derivatives and processes for obtaining them
KR0174117B1 (ko) *	1995-12-28	1999-02-01	윤원영	새로운 세팔로스포린 유도체 및 그 제조방법
CN107868812A (zh) *	2017-12-20	2018-04-03	焦作健康元生物制品有限公司	一种7‑氨基头孢烷酸的改进生产工艺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS507158B1 (sv) *	1968-08-02	1975-03-22
BE793448A (fr) *	1971-12-31	1973-06-28	Roussel Uclaf	Procede de preparation de nouveaux derives des cephalosporines et produits obtenus
US3928324A (en) *	1973-02-08	1975-12-23	Pfizer	Malonyl derivatives of 6-({60 -aminoacylamido)penicillanic acids
US3932392A (en) *	1974-01-14	1976-01-13	Bristol-Myers Company	Process for the preparation of 7-aminocephalosporanic acids

1976
- 1976-01-20 US US05/650,701 patent/US4079180A/en not_active Expired - Lifetime
- 1976-01-20 GB GB2162/76A patent/GB1494452A/en not_active Expired
- 1976-01-21 FR FR7601588A patent/FR2298552A1/fr active Granted
- 1976-01-21 NL NL7600602.A patent/NL163789C/xx not_active IP Right Cessation
- 1976-01-21 IT IT47732/76A patent/IT1053405B/it active
- 1976-01-21 DE DE19762659857 patent/DE2659857A1/de not_active Ceased
- 1976-01-21 CA CA243,992A patent/CA1069120A/en not_active Expired
- 1976-01-21 HU HU76AA00000842A patent/HU171208B/hu unknown
- 1976-01-21 SE SE7600585A patent/SE427184B/sv not_active IP Right Cessation
- 1976-01-21 CH CH74376A patent/CH621124A5/de not_active IP Right Cessation
- 1976-01-21 DK DK022576A patent/DK153554C/da not_active IP Right Cessation
- 1976-01-21 BE BE163675A patent/BE837766A/xx not_active IP Right Cessation
- 1976-01-21 DE DE2602099A patent/DE2602099C3/de not_active Expired

Also Published As

Publication number	Publication date
CH621124A5 (sv)	1981-01-15
IT1053405B (it)	1981-08-31
DE2659857A1 (de)	1977-10-27
NL163789B (nl)	1980-05-16
NL163789C (nl)	1980-10-15
DE2602099A1 (de)	1976-07-29
CA1069120A (en)	1980-01-01
DK22576A (da)	1976-07-23
GB1494452A (en)	1977-12-07
DK153554B (da)	1988-07-25
DE2602099B2 (de)	1978-10-05
SE427184B (sv)	1983-03-14
BE837766A (fr)	1976-05-14
DK153554C (da)	1988-12-05
US4079180A (en)	1978-03-14
FR2298552A1 (fr)	1976-08-20
DE2602099C3 (de)	1979-05-23
HU171208B (hu)	1977-12-28
NL7600602A (nl)	1976-07-26
FR2298552B1 (sv)	1978-07-21

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