SE7607201L - Forfarande for framstellning av nya tienopyridinderivat - Google Patents
Forfarande for framstellning av nya tienopyridinderivatInfo
- Publication number
- SE7607201L SE7607201L SE7607201A SE7607201A SE7607201L SE 7607201 L SE7607201 L SE 7607201L SE 7607201 A SE7607201 A SE 7607201A SE 7607201 A SE7607201 A SE 7607201A SE 7607201 L SE7607201 L SE 7607201L
- Authority
- SE
- Sweden
- Prior art keywords
- chr2
- carbon atoms
- derivatives
- alkyl
- tienopyridine
- Prior art date
Links
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- -1 phenoxy, benzoyl Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- 125000003866 trichloromethyl group Chemical group ClC(Cl)(Cl)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7520241A FR2315274A1 (fr) | 1975-06-27 | 1975-06-27 | Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7607201L true SE7607201L (sv) | 1976-12-28 |
| SE421698B SE421698B (sv) | 1982-01-25 |
Family
ID=9157178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7607201A SE421698B (sv) | 1975-06-27 | 1976-06-23 | Forfarande for framstellning av 4,5,6,7-tetrahydro-tieno (2,3-c) pyridinderivat |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4075340A (sv) |
| JP (1) | JPS607633B2 (sv) |
| AR (1) | AR211777A1 (sv) |
| AT (1) | AT347950B (sv) |
| BE (1) | BE843402A (sv) |
| CA (1) | CA1071635A (sv) |
| CH (1) | CH596169A5 (sv) |
| DD (1) | DD125080A5 (sv) |
| DE (1) | DE2628045A1 (sv) |
| DK (1) | DK279976A (sv) |
| ES (1) | ES449191A1 (sv) |
| FR (1) | FR2315274A1 (sv) |
| GB (1) | GB1492239A (sv) |
| GR (1) | GR60042B (sv) |
| HU (1) | HU172697B (sv) |
| IE (1) | IE43915B1 (sv) |
| IL (1) | IL49702A (sv) |
| LU (1) | LU75230A1 (sv) |
| MX (1) | MX3565E (sv) |
| NL (1) | NL183032C (sv) |
| PL (1) | PL105962B1 (sv) |
| PT (1) | PT65271B (sv) |
| SE (1) | SE421698B (sv) |
| SU (1) | SU628820A3 (sv) |
| YU (1) | YU39480B (sv) |
| ZA (1) | ZA763270B (sv) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4127580A (en) * | 1975-02-07 | 1978-11-28 | Parcor | Process for the preparation of thieno-pyridine derivatives |
| FR2395271A1 (fr) * | 1977-06-21 | 1979-01-19 | Parcor | Procede de preparation de thieno (2,3-c) et thieno (3,2-c) pyridines |
| GB2038625B (en) * | 1978-12-29 | 1983-01-12 | Parcor | Therapeutic composition having an antithrombotic and antiblood-platelet-aggregating activity |
| US4749692A (en) * | 1977-06-22 | 1988-06-07 | Sanofi, S.A. | Therapeutic compositions having anti-thrombotic and anti-blood-platelet-aggregating activity |
| FR2397417A1 (fr) * | 1977-07-12 | 1979-02-09 | Parcor | Procede de preparation de derives de la thienopyridine |
| AT368504B (de) * | 1977-10-15 | 1982-10-25 | Boehringer Sohn Ingelheim | Verfahren zur herstellung neuer 4-phenyl-thieno- (2,3-c)-piperidine |
| US4321266A (en) * | 1980-10-06 | 1982-03-23 | Sanofi | 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-C] pyridine |
| FR2508453A1 (fr) * | 1981-06-30 | 1982-12-31 | Sanofi Sa | Procede de preparation de derives des (thienyl-2)- et thienyl-3)-2 ethylamines et produits ainsi obtenus |
| US4547514A (en) * | 1983-12-05 | 1985-10-15 | A. H. Robins Company, Incorporated | Aryloxy-N-(aminoalkyl)-1-pyrrolidine and piperidine carboxamides and carbothioamides having antiarrhythmic activity |
| DE3736664A1 (de) * | 1987-10-29 | 1989-05-11 | Boehringer Ingelheim Kg | Tetrahydro-furo- und -thieno(2,3-c)pyridine, ihre verwendung als arzneimittel und verfahren zu ihrer herstellung |
| US5294621A (en) * | 1992-10-07 | 1994-03-15 | Ortho Pharmaceutical Corporation | Thieno tetrahydropyridines useful as class III antiarrhythmic agents |
| WO2000000472A1 (en) * | 1998-06-30 | 2000-01-06 | Du Pont Pharmaceuticals Company | 5-ht7 receptor antagonists |
| US6090797A (en) * | 1998-09-02 | 2000-07-18 | Novo Nordisk A/S | 4,5,6,7-tetrahydro-thieno(2,3-C)pyridine derivatives |
| WO2000014090A1 (en) * | 1998-09-02 | 2000-03-16 | Novo Nordisk A/S | 4,5,6,7-tetrahydro-thieno[2,3-c]pyridine derivatives |
| US8914114B2 (en) | 2000-05-23 | 2014-12-16 | The Feinstein Institute For Medical Research | Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation |
| AU2003217747A1 (en) * | 2002-02-26 | 2003-09-09 | North Shore-Long Island Jewish Research Insitute | Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors |
| EP1734941A2 (en) | 2004-03-25 | 2006-12-27 | The Feinstein Institute for Medical Research | Neural tourniquet |
| US10912712B2 (en) | 2004-03-25 | 2021-02-09 | The Feinstein Institutes For Medical Research | Treatment of bleeding by non-invasive stimulation |
| US11207518B2 (en) | 2004-12-27 | 2021-12-28 | The Feinstein Institutes For Medical Research | Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway |
| WO2006073484A2 (en) | 2004-12-27 | 2006-07-13 | North Shore-Long Island Jewish Research Institute | Treating inflammatory disorders by electrical vagus nerve stimulation |
| US8391970B2 (en) | 2007-08-27 | 2013-03-05 | The Feinstein Institute For Medical Research | Devices and methods for inhibiting granulocyte activation by neural stimulation |
| WO2009146030A1 (en) | 2008-03-31 | 2009-12-03 | The Feinstein Institute For Medical Research | Methods and systems for reducing inflammation by neuromodulation of t-cell activity |
| US9662490B2 (en) | 2008-03-31 | 2017-05-30 | The Feinstein Institute For Medical Research | Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug |
| CN102215909B (zh) | 2008-11-18 | 2014-09-10 | 赛博恩特医疗器械公司 | 优化用于消炎刺激的电极放置的装置和方法 |
| US9211410B2 (en) | 2009-05-01 | 2015-12-15 | Setpoint Medical Corporation | Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation |
| US8788034B2 (en) | 2011-05-09 | 2014-07-22 | Setpoint Medical Corporation | Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation |
| US8996116B2 (en) | 2009-10-30 | 2015-03-31 | Setpoint Medical Corporation | Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction |
| EP2440284B1 (en) | 2009-06-09 | 2018-09-12 | Setpoint Medical Corporation | Nerve cuff with pocket for leadless stimulator |
| US9833621B2 (en) | 2011-09-23 | 2017-12-05 | Setpoint Medical Corporation | Modulation of sirtuins by vagus nerve stimulation |
| US11051744B2 (en) | 2009-11-17 | 2021-07-06 | Setpoint Medical Corporation | Closed-loop vagus nerve stimulation |
| EP2515996B1 (en) | 2009-12-23 | 2019-09-18 | Setpoint Medical Corporation | Neural stimulation devices and systems for treatment of chronic inflammation |
| US12172017B2 (en) | 2011-05-09 | 2024-12-24 | Setpoint Medical Corporation | Vagus nerve stimulation to treat neurodegenerative disorders |
| AU2013235487B2 (en) | 2012-03-23 | 2017-09-07 | Memorial Sloan-Kettering Cancer Center | Treatment of pancreatic and related cancers with 5-acyl-6,7-dihydrothieno[3,2-c]pyridines |
| US9572983B2 (en) | 2012-03-26 | 2017-02-21 | Setpoint Medical Corporation | Devices and methods for modulation of bone erosion |
| EP3180327B1 (en) * | 2014-07-28 | 2019-05-08 | Merck Sharp & Dohme Corp. | FACTOR XIa INHIBITORS |
| US11311725B2 (en) | 2014-10-24 | 2022-04-26 | Setpoint Medical Corporation | Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation |
| US11406833B2 (en) | 2015-02-03 | 2022-08-09 | Setpoint Medical Corporation | Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator |
| US10596367B2 (en) | 2016-01-13 | 2020-03-24 | Setpoint Medical Corporation | Systems and methods for establishing a nerve block |
| EP3405255B1 (en) | 2016-01-20 | 2025-12-31 | Setpoint Medical Corporation | IMPLANTABLE MICROSTIMULATORS AND INDUCTION CHARGING SYSTEMS |
| US11471681B2 (en) | 2016-01-20 | 2022-10-18 | Setpoint Medical Corporation | Batteryless implantable microstimulators |
| CN108882885A (zh) | 2016-01-20 | 2018-11-23 | 赛博恩特医疗器械公司 | 迷走神经刺激的控制 |
| US10583304B2 (en) | 2016-01-25 | 2020-03-10 | Setpoint Medical Corporation | Implantable neurostimulator having power control and thermal regulation and methods of use |
| EP3668402B1 (en) | 2017-08-14 | 2024-07-31 | Setpoint Medical Corporation | Vagus nerve stimulation pre-screening test |
| US11260229B2 (en) | 2018-09-25 | 2022-03-01 | The Feinstein Institutes For Medical Research | Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation |
| US12343535B2 (en) | 2019-04-12 | 2025-07-01 | Setpoint Medical Corporation | Vagus nerve stimulation to treat neurodegenerative disorders |
| EP4090424A4 (en) | 2020-01-13 | 2024-02-21 | The Feinstein Institutes for Medical Research | TREATMENT OF BLEEDING AND BLEEDING DISORDERS BY HIGH-INTENSITY FOCUSED ULTRASONIC STIMULATION OF THE SPLEEN |
| US11938324B2 (en) | 2020-05-21 | 2024-03-26 | The Feinstein Institutes For Medical Research | Systems and methods for vagus nerve stimulation |
| WO2022245878A1 (en) | 2021-05-17 | 2022-11-24 | Setpoint Medical Corporation | Neurostimulation parameter authentication and expiration system for neurostimulation |
| EP4466064A4 (en) | 2022-01-20 | 2026-01-14 | Setpoint Medical Corp | TREATMENT OF INFLAMMATORY DISORDERS |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2215948B1 (sv) * | 1973-02-01 | 1976-05-14 | Centre Etd Ind Pharma |
-
1975
- 1975-06-27 FR FR7520241A patent/FR2315274A1/fr active Granted
-
1976
- 1976-05-17 CH CH612276A patent/CH596169A5/xx not_active IP Right Cessation
- 1976-05-31 IE IE1149/76A patent/IE43915B1/en unknown
- 1976-06-01 IL IL49702A patent/IL49702A/xx unknown
- 1976-06-01 GR GR50863A patent/GR60042B/el unknown
- 1976-06-02 US US05/692,186 patent/US4075340A/en not_active Expired - Lifetime
- 1976-06-02 ZA ZA763270A patent/ZA763270B/xx unknown
- 1976-06-14 SU SU762367256A patent/SU628820A3/ru active
- 1976-06-15 YU YU1462/76A patent/YU39480B/xx unknown
- 1976-06-17 NL NLAANVRAGE7606574,A patent/NL183032C/xx not_active IP Right Cessation
- 1976-06-21 CA CA255,299A patent/CA1071635A/en not_active Expired
- 1976-06-22 DK DK279976A patent/DK279976A/da unknown
- 1976-06-23 DE DE19762628045 patent/DE2628045A1/de not_active Ceased
- 1976-06-23 SE SE7607201A patent/SE421698B/sv not_active IP Right Cessation
- 1976-06-24 AT AT461776A patent/AT347950B/de not_active IP Right Cessation
- 1976-06-24 LU LU75230A patent/LU75230A1/xx unknown
- 1976-06-24 PT PT65271A patent/PT65271B/pt unknown
- 1976-06-24 AR AR263737A patent/AR211777A1/es active
- 1976-06-25 GB GB26591/76A patent/GB1492239A/en not_active Expired
- 1976-06-25 MX MX76799U patent/MX3565E/es unknown
- 1976-06-25 ES ES449191A patent/ES449191A1/es not_active Expired
- 1976-06-25 HU HU76PA00001254A patent/HU172697B/hu not_active IP Right Cessation
- 1976-06-25 DD DD193581A patent/DD125080A5/xx unknown
- 1976-06-25 BE BE168304A patent/BE843402A/xx not_active IP Right Cessation
- 1976-06-26 PL PL1976190741A patent/PL105962B1/pl unknown
- 1976-06-26 JP JP51075943A patent/JPS607633B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS525793A (en) | 1977-01-17 |
| IE43915B1 (en) | 1981-07-01 |
| HU172697B (hu) | 1978-11-28 |
| DD125080A5 (sv) | 1977-03-30 |
| PT65271A (fr) | 1976-07-01 |
| MX3565E (es) | 1981-03-13 |
| NL7606574A (nl) | 1976-12-29 |
| CA1071635A (en) | 1980-02-12 |
| GR60042B (en) | 1978-04-01 |
| SE421698B (sv) | 1982-01-25 |
| NL183032C (nl) | 1988-07-01 |
| AU1537576A (en) | 1978-01-05 |
| ES449191A1 (es) | 1977-12-01 |
| NL183032B (nl) | 1988-02-01 |
| IE43915L (en) | 1976-12-27 |
| ATA461776A (de) | 1978-06-15 |
| LU75230A1 (sv) | 1977-02-18 |
| ZA763270B (en) | 1977-05-25 |
| AR211777A1 (es) | 1978-03-15 |
| PL105962B1 (pl) | 1979-11-30 |
| BE843402A (fr) | 1976-12-27 |
| CH596169A5 (sv) | 1978-02-28 |
| FR2315274B1 (sv) | 1979-08-10 |
| GB1492239A (en) | 1977-11-16 |
| DE2628045A1 (de) | 1977-01-20 |
| US4075340A (en) | 1978-02-21 |
| FR2315274A1 (fr) | 1977-01-21 |
| AT347950B (de) | 1979-01-25 |
| PT65271B (fr) | 1977-12-10 |
| YU39480B (en) | 1984-12-31 |
| DK279976A (da) | 1976-12-28 |
| SU628820A3 (ru) | 1978-10-15 |
| YU146276A (en) | 1982-05-31 |
| JPS607633B2 (ja) | 1985-02-26 |
| IL49702A0 (en) | 1976-08-31 |
| IL49702A (en) | 1979-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 7607201-6 Effective date: 19940110 Format of ref document f/p: F |