SE7610501L - NEW N-ARYL-N (1-L-4-PIPERIDINYL) -ARYLACETAMIDES - Google Patents

NEW N-ARYL-N (1-L-4-PIPERIDINYL) -ARYLACETAMIDES

Info

Publication number
SE7610501L
SE7610501L SE7610501A SE7610501A SE7610501L SE 7610501 L SE7610501 L SE 7610501L SE 7610501 A SE7610501 A SE 7610501A SE 7610501 A SE7610501 A SE 7610501A SE 7610501 L SE7610501 L SE 7610501L
Authority
SE
Sweden
Prior art keywords
arylacetamides
piperidinyl
aryl
new
formula
Prior art date
Application number
SE7610501A
Other languages
Swedish (sv)
Other versions
SE427839B (en
Inventor
S Sanczuk
H K F Hermans
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SE7610501L publication Critical patent/SE7610501L/en
Publication of SE427839B publication Critical patent/SE427839B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

N-Aryl-N-(4-piperidinyl)arylacetamides of the formula <IMAGE> and their salts with acids, the substituents in the formula being defined in Claim 1, are prepared. These compounds are obtained by acylating corresponding piperidine derivatives with an arylacetyl halide. The resulting compounds can be used for the drug therapy of cardiac arrhythmias.
SE7610501A 1975-09-23 1976-09-22 ANALOGY PROCEDURES FOR THE PREPARATION OF N-ARYL-N- (1-L-4-PIPERIDINYL) -ARYL-ACETAMIDES SE427839B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61513175A 1975-09-23 1975-09-23
US71375676A 1976-08-12 1976-08-12

Publications (2)

Publication Number Publication Date
SE7610501L true SE7610501L (en) 1977-03-24
SE427839B SE427839B (en) 1983-05-09

Family

ID=27087421

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7610501A SE427839B (en) 1975-09-23 1976-09-22 ANALOGY PROCEDURES FOR THE PREPARATION OF N-ARYL-N- (1-L-4-PIPERIDINYL) -ARYL-ACETAMIDES

Country Status (29)

Country Link
JP (1) JPS6016417B2 (en)
AT (1) AT363935B (en)
AU (1) AU510029B2 (en)
BG (1) BG27543A3 (en)
CA (1) CA1068271A (en)
CH (1) CH628623A5 (en)
CS (1) CS222663B2 (en)
DE (1) DE2642856A1 (en)
DK (1) DK150478C (en)
ES (1) ES451768A1 (en)
FI (1) FI61482C (en)
FR (1) FR2325377A1 (en)
GB (1) GB1539473A (en)
GR (1) GR58469B (en)
HU (1) HU172964B (en)
IE (1) IE43802B1 (en)
IL (1) IL50522A (en)
IT (1) IT1073893B (en)
LU (1) LU75837A1 (en)
NL (1) NL187267C (en)
NO (1) NO147672C (en)
NZ (1) NZ181972A (en)
PH (1) PH12497A (en)
PL (2) PL192578A1 (en)
PT (1) PT65631B (en)
RO (1) RO70079A (en)
SE (1) SE427839B (en)
SU (1) SU747424A3 (en)
YU (1) YU39973B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA765684B (en) * 1975-09-23 1978-04-26 Janssen Pharmaceutica Nv Novel n-aryl-n-(1-l-4-piperidinyl)-arylacetamides
JPS62260786A (en) * 1986-05-08 1987-11-13 株式会社ヘキトク Line system for manufacturing smoked roof tile
JO2769B1 (en) 2005-10-26 2014-03-15 جانسين فارماسوتيكا ان. في Fast Dissociting Dopamine 2 Receptor Antagonists
JO2642B1 (en) 2006-12-08 2012-06-17 جانسين فارماسوتيكا ان. في Fast Dissociating Dopamine 2 Receptor Antagonists
JO2849B1 (en) 2007-02-13 2015-03-15 جانسين فارماسوتيكا ان. في Fast -Dissociating Dopamine 2 Receptor Antagonists
AU2008240729B2 (en) 2007-04-23 2012-08-23 Janssen Pharmaceutica N.V. Thia(dia)zoles as fast dissociating dopamine 2 receptor antagonists
KR20100016620A (en) 2007-04-23 2010-02-12 얀센 파마슈티카 엔.브이. 4-alkoxypyridazine derivatives as fast dissociating dopamine 2 receptor antagonists
WO2008128994A1 (en) * 2007-04-23 2008-10-30 Janssen Pharmaceutica N.V. Pyridine derivatives as fast dissociating dopamine 2 receptor antagonists
RU2502734C2 (en) 2008-07-03 2013-12-27 Янссен Фармацевтика Нв Substituted 6-(1-piperazinyl)-pyridazines as 5-ht6 receptor antagonists
CA2730774C (en) 2008-07-31 2016-09-13 Janssen Pharmaceutica Nv Piperazin-1-yl-trifluoromethyl-substituted-pyridines as fast dissociating dopamine 2 receptor antagonists
CN118496638B (en) * 2024-07-22 2024-11-22 海安浩驰科技有限公司 Anti-ultraviolet window film and preparation method thereof

Also Published As

Publication number Publication date
IL50522A0 (en) 1976-11-30
FR2325377A1 (en) 1977-04-22
AU510029B2 (en) 1980-06-05
PT65631B (en) 1978-07-05
CA1068271A (en) 1979-12-18
IL50522A (en) 1979-09-30
FI61482B (en) 1982-04-30
PL192578A1 (en) 1979-02-26
DK427876A (en) 1977-03-24
SE427839B (en) 1983-05-09
DE2642856A1 (en) 1977-03-24
NL7610513A (en) 1977-03-25
NL187267B (en) 1991-03-01
YU233676A (en) 1983-01-21
PH12497A (en) 1979-04-05
GB1539473A (en) 1979-01-31
NO763054L (en) 1977-03-24
NL187267C (en) 1991-08-01
CH628623A5 (en) 1982-03-15
DK150478B (en) 1987-03-09
PL117323B1 (en) 1981-07-31
NZ181972A (en) 1978-07-28
ATA702976A (en) 1981-02-15
NO147672C (en) 1983-05-25
AT363935B (en) 1981-09-10
PT65631A (en) 1976-10-01
IE43802L (en) 1977-03-23
DK150478C (en) 1987-10-05
NO147672B (en) 1983-02-14
YU39973B (en) 1985-06-30
LU75837A1 (en) 1977-05-04
FI762698A7 (en) 1977-03-24
IE43802B1 (en) 1981-06-03
HU172964B (en) 1979-01-28
JPS5239683A (en) 1977-03-28
DE2642856C2 (en) 1990-06-21
IT1073893B (en) 1985-04-17
CS222663B2 (en) 1983-07-29
AU1787876A (en) 1978-03-23
GR58469B (en) 1977-10-14
JPS6016417B2 (en) 1985-04-25
BG27543A3 (en) 1979-11-12
ES451768A1 (en) 1978-05-01
FI61482C (en) 1982-08-10
SU747424A3 (en) 1980-07-23
FR2325377B1 (en) 1980-04-18
RO70079A (en) 1982-10-26

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