SE7611885L - Sett att separera diindolalkaloider - Google Patents

Sett att separera diindolalkaloider

Info

Publication number: SE7611885L
Authority: SE; Sweden
Prior art keywords: diindol; alkaloids; separate; way; leurosine
Prior art date: 1975-10-28

Application number

SE7611885A

Other languages

English (en)

Other versions

SE430163B (sv

Inventor

K Jovanovics

K Szasz

C Lorincz

L Hermann

E Dezseri

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-10-28

Filing date

1976-10-26

Publication date

1977-04-29

1976-10-26 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

1977-04-29 Publication of SE7611885L publication Critical patent/SE7611885L/sv

1983-10-24 Publication of SE430163B publication Critical patent/SE430163B/sv

Links

229930013930 alkaloid Natural products 0.000 title abstract 2
240000001829 Catharanthus roseus Species 0.000 abstract 1
241000196324 Embryophyta Species 0.000 abstract 1
LPGWZGMPDKDHEP-HLTPFJCJSA-N Leurosine Chemical compound C([C@]1([C@@H]2O1)CC)N(CCC=1C3=CC=CC=C3NC=11)C[C@H]2C[C@]1(C(=O)OC)C1=CC([C@]23[C@H]([C@@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC LPGWZGMPDKDHEP-HLTPFJCJSA-N 0.000 abstract 1
LPGWZGMPDKDHEP-GKWAKPNHSA-N Leurosine Natural products O=C(O[C@H]1[C@](O)(C(=O)OC)[C@@H]2N(C)c3c(cc(c(OC)c3)[C@]3(C(=O)OC)c4[nH]c5c(c4CCN4C[C@]6(CC)O[C@@H]6[C@H](C3)C4)cccc5)[C@@]32[C@H]2[C@@]1(CC)C=CCN2CC3)C LPGWZGMPDKDHEP-GKWAKPNHSA-N 0.000 abstract 1
JXLYSJRDGCGARV-WWYNWVTFSA-N Vinblastine Natural products O=C(O[C@H]1[C@](O)(C(=O)OC)[C@@H]2N(C)c3c(cc(c(OC)c3)[C@]3(C(=O)OC)c4[nH]c5c(c4CCN4C[C@](O)(CC)C[C@H](C3)C4)cccc5)[C@@]32[C@H]2[C@@]1(CC)C=CCN2CC3)C JXLYSJRDGCGARV-WWYNWVTFSA-N 0.000 abstract 1
238000000605 extraction Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
238000011084 recovery Methods 0.000 abstract 1
238000000926 separation method Methods 0.000 abstract 1
229960003048 vinblastine Drugs 0.000 abstract 1
JXLYSJRDGCGARV-XQKSVPLYSA-N vincaleukoblastine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-XQKSVPLYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines Containing Plant Substances (AREA)
Peptides Or Proteins (AREA)

SE7611885A 1975-10-28 1976-10-26 Sett att separera leurosin och vinblastin SE430163B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU75RI00000581A HU172708B (hu)	1975-10-28	1975-10-28	Novyj sposob razdelenija diindolil-alkaloidov

Publications (2)

Publication Number	Publication Date
SE7611885L true SE7611885L (sv)	1977-04-29
SE430163B SE430163B (sv)	1983-10-24

Family

ID=11000989

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7611885A SE430163B (sv)	1975-10-28	1976-10-26	Sett att separera leurosin och vinblastin

Country Status (18)

Country	Link
US (1)	US4070358A (sv)
JP (1)	JPS5285198A (sv)
AT (1)	AT351175B (sv)
BE (1)	BE847734A (sv)
BG (1)	BG24675A3 (sv)
CH (1)	CH601319A5 (sv)
CS (1)	CS199648B2 (sv)
DD (1)	DD126340A5 (sv)
DE (1)	DE2648284A1 (sv)
FR (1)	FR2329670A1 (sv)
GB (1)	GB1517614A (sv)
HU (1)	HU172708B (sv)
NL (1)	NL187115C (sv)
PL (1)	PL103507B1 (sv)
RO (1)	RO73276A (sv)
SE (1)	SE430163B (sv)
SU (1)	SU912034A3 (sv)
YU (1)	YU261376A (sv)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU775373B2 (en)	1999-10-01	2004-07-29	Immunogen, Inc.	Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3097137A (en) *	1960-05-19	1963-07-09	Canadian Patents Dev	Vincaleukoblastine
US3225030A (en) *	1965-02-15	1965-12-21	Lilly Co Eli	Method of preparing leurosine and vincaleukoblastine
DE2124023C3 (de) *	1970-05-27	1980-07-10	Richter Gedeon Vegyeszeti Gyar R.T., Budapest	Verfahren zur selektiven Gewinnung von Vinblastin, Vinleurosin und Vincristin oder von deren Sulfaten
GB1382460A (en) *	1972-12-04	1975-01-29	Richter Gedeon Vegyeszet	Vincristine separation process
US3944554A (en) *	1975-01-09	1976-03-16	Eli Lilly And Company	4-Desacetoxy-3-hydroxyvinblastine

1975
- 1975-10-28 HU HU75RI00000581A patent/HU172708B/hu not_active IP Right Cessation
1976
- 1976-10-15 CH CH1311276A patent/CH601319A5/xx not_active IP Right Cessation
- 1976-10-18 CS CS766712A patent/CS199648B2/cs unknown
- 1976-10-19 AT AT776476A patent/AT351175B/de not_active IP Right Cessation
- 1976-10-20 BG BG034483A patent/BG24675A3/xx unknown
- 1976-10-22 US US05/735,004 patent/US4070358A/en not_active Expired - Lifetime
- 1976-10-25 DE DE19762648284 patent/DE2648284A1/de active Granted
- 1976-10-26 YU YU02613/76A patent/YU261376A/xx unknown
- 1976-10-26 DD DD195454A patent/DD126340A5/xx unknown
- 1976-10-26 SE SE7611885A patent/SE430163B/sv not_active IP Right Cessation
- 1976-10-26 FR FR7632209A patent/FR2329670A1/fr active Granted
- 1976-10-27 GB GB44689/76A patent/GB1517614A/en not_active Expired
- 1976-10-27 PL PL1976193307A patent/PL103507B1/pl unknown
- 1976-10-27 SU SU762416206A patent/SU912034A3/ru active
- 1976-10-27 RO RO7688241A patent/RO73276A/ro unknown
- 1976-10-27 JP JP12840176A patent/JPS5285198A/ja active Granted
- 1976-10-28 BE BE171868A patent/BE847734A/xx not_active IP Right Cessation
- 1976-10-28 NL NLAANVRAGE7611945,A patent/NL187115C/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
CH601319A5 (sv)	1978-07-14
DE2648284A1 (de)	1977-06-02
YU261376A (en)	1982-06-30
GB1517614A (en)	1978-07-12
CS199648B2 (en)	1980-07-31
HU172708B (hu)	1978-11-28
RO73276A (ro)	1982-04-12
NL187115B (nl)	1991-01-02
AT351175B (de)	1979-07-10
JPS5527067B2 (sv)	1980-07-17
DD126340A5 (sv)	1977-07-13
DE2648284C2 (sv)	1987-11-05
BE847734A (fr)	1977-02-14
NL7611945A (nl)	1977-05-02
BG24675A3 (en)	1978-04-12
PL103507B1 (pl)	1979-06-30
SU912034A3 (ru)	1982-03-07
FR2329670A1 (fr)	1977-05-27
US4070358A (en)	1978-01-24
FR2329670B1 (sv)	1981-12-11
NL187115C (nl)	1991-06-03
SE430163B (sv)	1983-10-24
JPS5285198A (en)	1977-07-15
ATA776476A (de)	1978-12-15

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Legal Events

Date

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Title

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1995-01-31

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