SE7700946L - Klavulansyrationetrar - Google Patents

Klavulansyrationetrar

Info

Publication number: SE7700946L
Authority: SE; Sweden
Prior art keywords: acidations; clavulanic; group; beta; ester
Prior art date: 1976-01-31

Application number

SE7700946A

Other languages

English (en)

Other versions

SE441359B (sv

Inventor

R J Ponsford

Original Assignee

Beecham Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-01-31

Filing date

1977-01-28

Publication date

1977-08-01

1976-01-31 Priority claimed from GB3892/76A external-priority patent/GB1574906A/en

1977-01-28 Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd

1977-08-01 Publication of SE7700946L publication Critical patent/SE7700946L/sv

1985-09-30 Publication of SE441359B publication Critical patent/SE441359B/sv

Links

150000001875 compounds Chemical class 0.000 abstract 2
239000004215 Carbon black (E152) Substances 0.000 abstract 1
108090000204 Dipeptidase 1 Proteins 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
102000006635 beta-lactamase Human genes 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000002843 carboxylic acid group Chemical group 0.000 abstract 1
230000015556 catabolic process Effects 0.000 abstract 1
238000006731 degradation reaction Methods 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
229930195733 hydrocarbon Natural products 0.000 abstract 1
150000002430 hydrocarbons Chemical class 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Cephalosporin Compounds (AREA)

SE7700946A 1976-01-31 1977-01-28 Forfarande for framstellning av nya klavulansyratioetrar SE441359B (sv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB3892/76A GB1574906A (en)	1976-01-31	1976-01-31	Therapeutic compounds containing - lactams
GB1900276		1976-05-08

Publications (2)

Publication Number	Publication Date
SE7700946L true SE7700946L (sv)	1977-08-01
SE441359B SE441359B (sv)	1985-09-30

Family

ID=26238678

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7700946A SE441359B (sv)	1976-01-31	1977-01-28	Forfarande for framstellning av nya klavulansyratioetrar

Country Status (31)

Country	Link
US (2)	US4428958A (sv)
JP (1)	JPS5295689A (sv)
AR (3)	AR214306A1 (sv)
AT (1)	AT351675B (sv)
AU (1)	AU515736B2 (sv)
BG (1)	BG27751A3 (sv)
CA (1)	CA1089471A (sv)
CH (2)	CH637655A5 (sv)
CS (1)	CS196341B2 (sv)
DD (1)	DD128196A5 (sv)
DE (1)	DE2702954A1 (sv)
DK (1)	DK146940C (sv)
ES (1)	ES455404A1 (sv)
FI (1)	FI63581C (sv)
FR (1)	FR2339616A1 (sv)
GR (1)	GR62544B (sv)
HK (1)	HK69883A (sv)
IE (1)	IE44759B1 (sv)
IL (1)	IL51267A (sv)
KE (1)	KE3303A (sv)
LU (1)	LU76668A1 (sv)
MX (1)	MX4950E (sv)
NL (1)	NL7700892A (sv)
NO (1)	NO770279L (sv)
NZ (1)	NZ183117A (sv)
PH (1)	PH13924A (sv)
PT (1)	PT66071B (sv)
RO (1)	RO69712A (sv)
SE (1)	SE441359B (sv)
SU (1)	SU645583A3 (sv)
YU (1)	YU10777A (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1582884A (en) *	1977-05-19	1981-01-14	Beecham Group Ltd	Clavulanic acid derivatives their preparation and use
GB2004541B (en) *	1977-09-16	1982-05-12	Beecham Group Ltd	Ethers of clavulanic acid a process for their preparation and pharmaceutical compositions containing them
DE2963679D1 (en) *	1978-09-05	1982-11-04	Beecham Group Plc	Clavulanic acid derivatives, their preparation and pharmaceutical compositions containing them
EP0018203B1 (en) *	1979-04-21	1983-03-02	Beecham Group Plc	Clavulanic acid derivatives, their preparation and use in pharmaceutical compositions
NZ193687A (en) *	1979-05-17	1982-12-21	Beecham Group Ltd	Clavulanic acid derivatives and pharmaceutical compositions
ZA804670B (en) *	1979-08-03	1981-07-29	Beecham Group Ltd	Derivatives of clavulanic acid, a process for their preparation and their use
NZ199061A (en) *	1980-12-09	1984-10-19	Beecham Group Ltd	9-(n-tetrazolyl)-deoxyclavulanic acids,salts,esters,and pharmaceutical compositions
NZ199200A (en) *	1980-12-23	1984-07-31	Beecham Group Ltd	Clavulanic acid derivatives and pharmaceutical compositions
GB9518917D0 (en) *	1995-09-15	1995-11-15	Smithkline Beecham Plc	Compounds
US5958462A (en) *	1997-05-23	1999-09-28	Mclean; Linsey	Therapeutic bath salts and method of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4039673A (en)	1973-10-30	1977-08-02	Bayer Aktiengesellschaft	Penicillins and cephalosporins and their production
US3983113A (en)	1975-08-15	1976-09-28	Syntex (U.S.A.) Inc.	Cephalosporin type antibacterials

1977
- 1977-01-14 IL IL51267A patent/IL51267A/xx unknown
- 1977-01-14 PT PT66071A patent/PT66071B/pt unknown
- 1977-01-17 YU YU00107/77A patent/YU10777A/xx unknown
- 1977-01-17 PH PH19356A patent/PH13924A/en unknown
- 1977-01-18 NZ NZ183117A patent/NZ183117A/xx unknown
- 1977-01-18 GR GR52592A patent/GR62544B/el unknown
- 1977-01-20 CS CS77387A patent/CS196341B2/cs unknown
- 1977-01-24 US US05/761,712 patent/US4428958A/en not_active Expired - Lifetime
- 1977-01-25 DE DE19772702954 patent/DE2702954A1/de not_active Withdrawn
- 1977-01-26 AR AR266318A patent/AR214306A1/es active
- 1977-01-26 BG BG035265A patent/BG27751A3/xx unknown
- 1977-01-26 CH CH94177A patent/CH637655A5/de not_active IP Right Cessation
- 1977-01-27 ES ES455404A patent/ES455404A1/es not_active Expired
- 1977-01-27 CA CA270,533A patent/CA1089471A/en not_active Expired
- 1977-01-28 SU SU772447048A patent/SU645583A3/ru active
- 1977-01-28 AT AT53477A patent/AT351675B/de not_active IP Right Cessation
- 1977-01-28 DD DD7700197138A patent/DD128196A5/xx unknown
- 1977-01-28 IE IE182/77A patent/IE44759B1/en unknown
- 1977-01-28 DK DK38577A patent/DK146940C/da not_active IP Right Cessation
- 1977-01-28 AU AU21770/77A patent/AU515736B2/en not_active Expired
- 1977-01-28 FI FI770295A patent/FI63581C/fi not_active IP Right Cessation
- 1977-01-28 FR FR7702402A patent/FR2339616A1/fr active Granted
- 1977-01-28 NO NO770279A patent/NO770279L/no unknown
- 1977-01-28 NL NL7700892A patent/NL7700892A/xx not_active Application Discontinuation
- 1977-01-28 SE SE7700946A patent/SE441359B/sv not_active IP Right Cessation
- 1977-01-28 MX MX775395U patent/MX4950E/es unknown
- 1977-01-28 LU LU76668A patent/LU76668A1/xx unknown
- 1977-01-29 JP JP917077A patent/JPS5295689A/ja active Granted
- 1977-01-31 RO RO197789185A patent/RO69712A/ro unknown
- 1977-11-14 AR AR269972A patent/AR216925A1/es active
1978
- 1978-11-07 AR AR274370A patent/AR216555A1/es active
1982
- 1982-08-30 US US06/412,591 patent/US4505894A/en not_active Expired - Fee Related
- 1982-12-16 CH CH734282A patent/CH638529A5/de not_active IP Right Cessation
1983
- 1983-07-14 KE KE3303A patent/KE3303A/xx unknown
- 1983-12-15 HK HK698/83A patent/HK69883A/xx unknown

Also Published As

Publication number	Publication date
PT66071B (en)	1978-06-23
FI63581B (fi)	1983-03-31
CA1089471A (en)	1980-11-11
DK146940C (da)	1984-07-30
LU76668A1 (sv)	1977-06-28
KE3303A (en)	1983-08-05
NO770279L (no)	1977-08-02
NL7700892A (nl)	1977-08-02
AU2177077A (en)	1978-08-03
AR216555A1 (es)	1979-12-28
BG27751A3 (bg)	1979-12-12
YU10777A (en)	1982-06-30
SE441359B (sv)	1985-09-30
IE44759L (en)	1977-07-31
CS196341B2 (en)	1980-03-31
CH638529A5 (de)	1983-09-30
IL51267A (en)	1979-12-30
AR214306A1 (es)	1979-05-31
ES455404A1 (es)	1978-05-01
FR2339616B1 (sv)	1980-04-11
AR216925A1 (es)	1980-02-15
DD128196A5 (de)	1977-11-02
RO69712A (fr)	1980-07-15
PH13924A (en)	1980-11-04
IE44759B1 (en)	1982-03-24
DK146940B (da)	1984-02-20
ATA53477A (de)	1979-01-15
MX4950E (es)	1983-01-12
PT66071A (en)	1977-02-01
FI770295A7 (sv)	1977-08-01
DK38577A (da)	1977-08-01
HK69883A (en)	1983-12-23
NZ183117A (en)	1979-10-25
US4428958A (en)	1984-01-31
DE2702954A1 (de)	1977-08-04
JPS5295689A (en)	1977-08-11
FI63581C (fi)	1983-07-11
US4505894A (en)	1985-03-19
CH637655A5 (de)	1983-08-15
FR2339616A1 (fr)	1977-08-26
GR62544B (en)	1979-05-07
IL51267A0 (en)	1977-03-31
SU645583A3 (ru)	1979-01-30
AT351675B (de)	1979-08-10
JPS613349B2 (sv)	1986-01-31
AU515736B2 (en)	1981-04-30

Legal Events

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 7700946-2

Effective date: 19870915

Format of ref document f/p: F

Publication	Publication Date	Title
SE7504999L (sv)	1975-11-14	Cefalosporiner med -acylaminoettiksyrasidokedja.
ES459785A1 (es)	1978-12-01	Un procedimiento para la preparacion de nuevos esteres anti-bacterianos.
SE8401134D0 (sv)	1984-03-01	Forfarande for framstellning av dihydro-cyklosporin d
IT7825205A0 (it)	1978-06-30	Processo per l'ossidazione di composti aromatici sostituiti ad acidi carbossilici aromatici
IE852229L (en)	1981-04-22	Penicillin compounds
NO904377D0 (no)	1990-10-10	Tricykliske karbapenemforbindelser.
SE7611047L (sv)	1977-04-14	Forfarande for framstellning av antibakteriella emnen
AT367764B (de)	1982-07-26	Verfahren zur herstellung von neuen cephalosporin-derivaten
ES455404A1 (es)	1978-05-01	Un procedimiento para la preparacion de nuevos derivados de beta-lactama.
ES497872A0 (es)	1982-09-01	Un procedimiento mejorado de oxidacion de un compuesto organico.
SE7904731L (sv)	1979-12-02	Nya l-leucyl-4-hydroxianilidderivat
SE7709071L (sv)	1978-02-17	Olivansyraestrar
GR77088B (sv)	1984-09-06
IE44295L (en)	1977-04-13	Preparation of clavulanic acid
GB1493197A (en)	1977-11-23	Amides of clavulanic acid
JPS5690088A (en)	1981-07-21	Novel cephalosporin analog compound
ES8101603A1 (es)	1980-12-16	Un procedimiento para la preparacion de derivados de penici-lina o de cefalosporina
IE44192L (en)	1977-06-16	1-aza-4-oxabicyclo [3,2,0] heptene compounds
SE7503274L (sv)	1975-10-13	Cefalosporin
US4100178A (en)	1978-07-11	4,5-Didehydro-6-methoxy-2-arylmethoxymethyl-4α-tetrahydropyranacetic acid alkyl esters
US4100177A (en)	1978-07-11	4,5-Didehydro-6-hydroxy-2-arylmethoxymethyl-4α-tetrahydropyranacetic acid alkyl esters
GB2001531A (en)	1979-02-07	Organic compounds
US4100176A (en)	1978-07-11	4,5-Didehydro-6-hydroxy-2β-arylmethoxymethyl-4α-tetrahydropyranacetic acids
ES470902A1 (es)	1979-02-01	Procedimiento para la obtencion de un nuevo derivado cefa- losporanico
GB2004273A (en)	1979-03-28	beta -Lactam compounds, preparation and use