SE7703068L - Nya sulfonamido-bensoesyraderivat jemte sett for deras framstellning - Google Patents
Nya sulfonamido-bensoesyraderivat jemte sett for deras framstellningInfo
- Publication number
- SE7703068L SE7703068L SE7703068A SE7703068A SE7703068L SE 7703068 L SE7703068 L SE 7703068L SE 7703068 A SE7703068 A SE 7703068A SE 7703068 A SE7703068 A SE 7703068A SE 7703068 L SE7703068 L SE 7703068L
- Authority
- SE
- Sweden
- Prior art keywords
- denote
- furthermore
- group
- hydrogen atom
- acid derivatives
- Prior art date
Links
- -1 SULPHONAMIDO BENZOIC ACID DERIVATIVES Chemical class 0.000 title 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 125000004193 piperazinyl group Chemical group 0.000 abstract 3
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 abstract 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000717 hydrazino group Chemical group [H]N([*])N([H])[H] 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229960002748 norepinephrine Drugs 0.000 abstract 1
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762611705 DE2611705A1 (de) | 1976-03-18 | 1976-03-18 | N-5-(nitrofurfuryliden-)-1-amino- hydantoin enthaltende kristalloesungsmittel |
| HU76GO00001334A HU172949B (hu) | 1976-03-18 | 1976-03-18 | Sposob poluchenija novykh proizvodnykh sul'fonamido-benzojnoj kisloty |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7703068L true SE7703068L (sv) | 1977-09-19 |
Family
ID=25770228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7703068A SE7703068L (sv) | 1976-03-18 | 1977-03-17 | Nya sulfonamido-bensoesyraderivat jemte sett for deras framstellning |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4244871A (fr) |
| JP (1) | JPS52136146A (fr) |
| AT (1) | AT348981B (fr) |
| CA (1) | CA1092111A (fr) |
| DE (2) | DE2611705A1 (fr) |
| FR (1) | FR2344531A1 (fr) |
| GB (1) | GB1561243A (fr) |
| NL (1) | NL7702991A (fr) |
| SE (1) | SE7703068L (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58192820A (ja) * | 1982-05-06 | 1983-11-10 | Mochida Pharmaceut Co Ltd | 抗ウイルス作用を有する医薬組成物 |
| IT1176613B (it) * | 1984-08-14 | 1987-08-18 | Ravizza Spa | Derivati piperazinici farmacologicamente attivi e processo per la loro preparazione |
| JPS61134382A (ja) * | 1984-12-04 | 1986-06-21 | Kyorin Pharmaceut Co Ltd | 新規なスルファモイル安息香酸誘導体およびその製造法 |
| US6384080B1 (en) | 1998-04-20 | 2002-05-07 | Fujisawa Pharmaceutical Co., Ltd. | Anthranilic acid derivatives as inhibitors of the cGMP-phosphodiesterase |
| JP4563387B2 (ja) * | 2003-09-09 | 2010-10-13 | エフ．ホフマン−ラ ロシュ アーゲー | 精神病の処置のためのグリシン取り込み阻害剤としての１−ベンゾイル−ピペラジン誘導体 |
| DK1663232T3 (da) * | 2003-09-09 | 2008-02-04 | Hoffmann La Roche | Benzimidazolderivater som human chymase-inhibitorer |
| KR100880093B1 (ko) * | 2004-12-09 | 2009-01-23 | 에프. 호프만-라 로슈 아게 | 페닐-피페라진 메탄온 유도체 |
| CA2590316A1 (fr) * | 2004-12-15 | 2006-06-22 | F. Hoffmann-La Roche Ag | Utilisation de phenylmethanones substituees bicycliques et tricycliques comme inhibiteurs des transporteurs de la glycine i (glyt-1) pour traiter la maladie d'alzheimer |
| US7485637B2 (en) * | 2005-01-04 | 2009-02-03 | Hoffmann-La Roche Inc. | Benzoyl-tetrahydropiperidine derivatives |
| KR20070094955A (ko) * | 2005-01-06 | 2007-09-27 | 에프. 호프만-라 로슈 아게 | 신경 질환 및 신경정신 질환을 치료하기 위한 글라이신수송자 1(ｇｌｙｔ-1) 저해제로서의 설파닐 치환 페닐메타논 |
| RU2396270C2 (ru) * | 2005-01-07 | 2010-08-10 | Ф.Хоффманн-Ля Рош Аг | Производные [4-(гетероарил)пиперазин-1-ил]-(2,5-замещенный фенил)метанона в качестве ингибиторов переносчика глицина-1 (glyt-1) для лечения неврологических и психоневрологических заболеваний |
| JP2008527016A (ja) * | 2005-01-18 | 2008-07-24 | エフ．ホフマン−ラ ロシュ アーゲー | 神経及び神経精神病の疾患の治療のためのグリシントランスポーター１（ＧｌｙＴ−１）阻害剤としての２，５−二置換フェニルメタノン誘導体 |
| ES2332529T3 (es) * | 2005-01-26 | 2010-02-08 | F. Hoffmann-La Roche Ag | Derivados de fenil-metanona y su empleo como inhibidores del transportador 1 de glicina. |
| CN101119968B (zh) * | 2005-02-07 | 2011-08-31 | 弗·哈夫曼-拉罗切有限公司 | 作为甘氨酸转运蛋白1抑制剂的杂环取代的苯基甲酮衍生物 |
| GB0505086D0 (en) * | 2005-03-11 | 2005-04-20 | Glaxo Group Ltd | Compounds |
| WO2010005922A1 (fr) * | 2008-07-07 | 2010-01-14 | Fasgen, Inc. | Nouveaux composés, compositions pharmaceutiques les contenant, et leurs procédés d'utilisation et de préparation |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2910488A (en) * | 1958-01-22 | 1959-10-27 | Merck & Co Inc | Aniline derivatives |
| US3346568A (en) * | 1961-09-14 | 1967-10-10 | Ciba Geigy Corp | 2-amino-5-sulfamyl-benzoic acid hydrazides |
| FR1403935A (fr) * | 1963-06-05 | 1965-06-25 | Ciba Geigy | Nouveaux amides d'acides anthraniliques |
| US3839321A (en) * | 1966-07-21 | 1974-10-01 | Smithkline Corp | 5-sulfamoyl-n-(2-substituted-ethyl) anthranilic acids |
| US3522274A (en) * | 1967-05-24 | 1970-07-28 | American Home Prod | 2,3-dihydro-1-alkyl-7-sulfamoyl-4,1-benzoxazepin-5(1h)-ones |
| US3843662A (en) * | 1971-12-09 | 1974-10-22 | Pfizer | 2-halo-5-(substituted piperidino sulfonyl)benzoic acids |
| DE2232457A1 (de) * | 1972-07-01 | 1974-01-10 | Boehringer Mannheim Gmbh | Neue 3-alkyl-4-sulfamoylanilinderivate |
| DE2423847A1 (de) * | 1973-05-28 | 1975-01-02 | Ciba Geigy Ag | Neue sulfamoylbenzoesaeureamide |
| CH590262A5 (fr) * | 1973-07-10 | 1977-07-29 | Ciba Geigy Ag |
-
1976
- 1976-03-18 DE DE19762611705 patent/DE2611705A1/de active Pending
-
1977
- 1977-03-16 FR FR7707839A patent/FR2344531A1/fr active Granted
- 1977-03-16 AT AT180277A patent/AT348981B/de not_active IP Right Cessation
- 1977-03-17 GB GB11472/77A patent/GB1561243A/en not_active Expired
- 1977-03-17 CA CA274,162A patent/CA1092111A/fr not_active Expired
- 1977-03-17 SE SE7703068A patent/SE7703068L/xx not_active Application Discontinuation
- 1977-03-18 JP JP2938777A patent/JPS52136146A/ja active Pending
- 1977-03-18 NL NL7702991A patent/NL7702991A/xx not_active Application Discontinuation
- 1977-03-18 DE DE19772712023 patent/DE2712023A1/de not_active Withdrawn
-
1979
- 1979-07-12 US US06/058,363 patent/US4244871A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB1561243A (en) | 1980-02-13 |
| FR2344531A1 (fr) | 1977-10-14 |
| CA1092111A (fr) | 1980-12-23 |
| NL7702991A (nl) | 1977-09-20 |
| JPS52136146A (en) | 1977-11-14 |
| DE2611705A1 (de) | 1977-09-22 |
| FR2344531B1 (fr) | 1980-04-04 |
| US4244871A (en) | 1981-01-13 |
| DE2712023A1 (de) | 1977-10-06 |
| AT348981B (de) | 1979-03-12 |
| ATA180277A (de) | 1978-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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