SE7709234L - Antitumorantibiotika - Google Patents

Antitumorantibiotika

Info

Publication number: SE7709234L
Authority: SE; Sweden
Prior art keywords: rhodirubin; streptomyces; antitumorantibiotics; hei; atcc
Prior art date: 1976-08-16

Application number

SE7709234A

Other languages

English (en)

Other versions

SE435069B (sv

Inventor

H Umezawa

T Takeuchi

M Hamada

M Ishizuka

H Naganawa

T Oki

T Inui

Original Assignee

Microbial Chem Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-08-16

Filing date

1977-08-16

Publication date

1978-02-17

1977-08-16 Application filed by Microbial Chem Res Found filed Critical Microbial Chem Res Found

1978-02-17 Publication of SE7709234L publication Critical patent/SE7709234L/sv

1984-09-03 Publication of SE435069B publication Critical patent/SE435069B/sv

Links

241000192125 Firmicutes Species 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
229930189295 Rhodirubin Natural products 0.000 abstract 1
WGXOAYYFWFRVSV-UHFFFAOYSA-N Rhodirubin A Natural products C12=C(O)C=3C(=O)C4=C(O)C=CC(O)=C4C(=O)C=3C=C2C(C(=O)OC)C(CC)(O)CC1OC(OC1C)CC(N(C)C)C1OC(OC1C)CC(O)C1OC1CCC(O)C(C)O1 WGXOAYYFWFRVSV-UHFFFAOYSA-N 0.000 abstract 1
241000187747 Streptomyces Species 0.000 abstract 1
241000187180 Streptomyces sp. Species 0.000 abstract 1
229940045799 anthracyclines and related substance Drugs 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
230000004151 fermentation Effects 0.000 abstract 1
238000000855 fermentation Methods 0.000 abstract 1
229930182470 glycoside Natural products 0.000 abstract 1
150000002338 glycosides Chemical class 0.000 abstract 1
WGXOAYYFWFRVSV-JEGHDPRDSA-N methyl (1r,2r,4s)-4-[(2r,4s,5s,6s)-4-(dimethylamino)-5-[(2s,4s,5s,6s)-4-hydroxy-5-[(2s,5s,6s)-5-hydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,10-tetrahydroxy-6,11-dioxo-3,4-dihydro-1h-tetracene-1-carboxylate Chemical compound O([C@H]1[C@@H](O)C[C@@H](O[C@H]1C)O[C@H]1[C@H](C[C@@H](O[C@H]1C)O[C@H]1C[C@]([C@@H](C2=CC=3C(=O)C4=C(O)C=CC(O)=C4C(=O)C=3C(O)=C21)C(=O)OC)(O)CC)N(C)C)[C@H]1CC[C@H](O)[C@H](C)O1 WGXOAYYFWFRVSV-JEGHDPRDSA-N 0.000 abstract 1
VGXIKBCXEHBHIQ-DBKSDKBWSA-N methyl (1r,2r,4s)-4-[(2r,4s,5s,6s)-4-(dimethylamino)-5-[(2s,5s,6s)-5-[(2s,5s,6s)-5-hydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,10-tetrahydroxy-6,11-dioxo-3,4-dihydro-1h-tetracene-1-carboxylate Chemical compound O([C@H]1CC[C@@H](O[C@H]1C)O[C@H]1[C@H](C[C@@H](O[C@H]1C)O[C@H]1C[C@]([C@@H](C2=CC=3C(=O)C4=C(O)C=CC(O)=C4C(=O)C=3C(O)=C21)C(=O)OC)(O)CC)N(C)C)[C@H]1CC[C@H](O)[C@H](C)O1 VGXIKBCXEHBHIQ-DBKSDKBWSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

SE7709234A 1976-08-16 1977-08-16 Forfarande for framstellning av nya antracyklinglykosider, benemnda rhodirubin a och b, genom odling av vissa stammar tillhorande slektet streptomyces SE435069B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP9811376A JPS5323961A (en)	1976-08-16	1976-08-16	Antitumors

Publications (2)

Publication Number	Publication Date
SE7709234L true SE7709234L (sv)	1978-02-17
SE435069B SE435069B (sv)	1984-09-03

Family

ID=14211256

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7709234A SE435069B (sv)	1976-08-16	1977-08-16	Forfarande for framstellning av nya antracyklinglykosider, benemnda rhodirubin a och b, genom odling av vissa stammar tillhorande slektet streptomyces

Country Status (16)

Country	Link
US (1)	US4127714A (sv)
JP (1)	JPS5323961A (sv)
AU (1)	AU512279B2 (sv)
BE (1)	BE857840A (sv)
CA (1)	CA1099652A (sv)
CH (1)	CH630958A5 (sv)
DK (1)	DK146282C (sv)
FI (1)	FI59613C (sv)
FR (1)	FR2362157A1 (sv)
GB (1)	GB1561619A (sv)
IE (1)	IE45557B1 (sv)
LU (1)	LU77970A1 (sv)
NL (1)	NL7709028A (sv)
SE (1)	SE435069B (sv)
YU (1)	YU39815B (sv)
ZA (1)	ZA774967B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS52136159A (en) *	1976-04-07	1977-11-14	Microbial Chem Res Found	Anti/malignanttumor containing the same as active ingredients
US4123608A (en) *	1977-07-18	1978-10-31	Bristol-Myers Company	Antibiotic compound
US4277466A (en) *	1978-08-29	1981-07-07	Institut International De Pathologie Cellulaire Et Moleculaire	Complexes of DNA and esters derived from daunorubicine, their preparation and use
JPS6023679B2 (ja) *	1979-07-13	1985-06-08	メルシャン株式会社	ロドマイシン群抗生物質とその製造法
PL124284B1 (en) *	1979-10-17	1983-01-31	Politechnika Gdanska	Process for preparing n-glycosyl derivatives of antibiotics from anthracyclines group
JPS5731696A (en) *	1980-08-01	1982-02-20	Sanraku Inc	Anthracycline derivative
CH648327A5 (de) *	1980-10-16	1985-03-15	Hoffmann La Roche	Anthracycline.
DE3323025A1 (de) *	1983-06-25	1985-01-10	Hoechst Ag, 6230 Frankfurt	Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika
US20050208037A1 (en) *	2003-10-21	2005-09-22	Board Of Regents, The University Of Texas System	Thioredoxin increases redox-cycling of anticancer agents thereby sensitizes cancer cells to apoptosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5134915B2 (sv) *	1974-07-27	1976-09-29
US4039736A (en) *	1976-04-15	1977-08-02	Bristol-Myers Company	Antibiotic compounds marcellomycin and musettamycin

1976
- 1976-08-16 JP JP9811376A patent/JPS5323961A/ja active Granted
1977
- 1977-08-09 US US05/823,052 patent/US4127714A/en not_active Expired - Lifetime
- 1977-08-15 YU YU1972/77A patent/YU39815B/xx unknown
- 1977-08-15 IE IE1698/77A patent/IE45557B1/en unknown
- 1977-08-15 CA CA284,688A patent/CA1099652A/en not_active Expired
- 1977-08-15 GB GB34167/77A patent/GB1561619A/en not_active Expired
- 1977-08-15 FI FI772442A patent/FI59613C/fi not_active IP Right Cessation
- 1977-08-16 AU AU27937/77A patent/AU512279B2/en not_active Expired
- 1977-08-16 BE BE180220A patent/BE857840A/xx not_active IP Right Cessation
- 1977-08-16 CH CH1000277A patent/CH630958A5/de not_active IP Right Cessation
- 1977-08-16 ZA ZA00774967A patent/ZA774967B/xx unknown
- 1977-08-16 SE SE7709234A patent/SE435069B/sv not_active IP Right Cessation
- 1977-08-16 LU LU77970A patent/LU77970A1/xx unknown
- 1977-08-16 NL NL7709028A patent/NL7709028A/xx not_active Application Discontinuation
- 1977-08-16 FR FR7725022A patent/FR2362157A1/fr active Granted
- 1977-08-16 DK DK364677A patent/DK146282C/da active

Also Published As

Publication number	Publication date
DK364677A (da)	1978-02-17
FI772442A7 (fi)	1978-02-17
DK146282B (da)	1983-08-22
US4127714A (en)	1978-11-28
SE435069B (sv)	1984-09-03
AU512279B2 (en)	1980-10-02
AU2793777A (en)	1979-02-22
YU197277A (en)	1982-06-30
IE45557B1 (en)	1982-09-22
YU39815B (en)	1985-04-30
ZA774967B (en)	1978-06-28
GB1561619A (en)	1980-02-27
CH630958A5 (de)	1982-07-15
FR2362157A1 (fr)	1978-03-17
FI59613C (fi)	1981-09-10
BE857840A (fr)	1978-02-16
IE45557L (en)	1978-02-16
DK146282C (da)	1984-01-30
NL7709028A (nl)	1978-02-20
LU77970A1 (sv)	1978-04-27
JPS5438103B2 (sv)	1979-11-19
CA1099652A (en)	1981-04-21
FI59613B (fi)	1981-05-29
JPS5323961A (en)	1978-03-06
FR2362157B1 (sv)	1981-03-20

Legal Events

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 7709234-4

Effective date: 19920306

Format of ref document f/p: F

Publication	Publication Date	Title
ES2052574T3 (es)	1994-07-16	Antibioticos glicopeptidos.
SE7508450L (sv)	1976-01-28	Antitumorantibiotika aklacinomycin a och b.
SE7710972L (sv)	1978-04-06	Nya antitumor-antracyklinantibiotika
SE7709234L (sv)	1978-02-17	Antitumorantibiotika
SE7703760L (sv)	1977-10-08	Antibiotika
ATE37394T1 (de)	1988-10-15	Antitumor-antibiotika.
NO163574C (no)	1990-06-20	Fremgangsmaate for fremstilling av antitumor-antibiotika (ll-e33288 kompleks) ved fermentering av micromonospora echinospora ssp. calichensis nrrl 1539 og nrrl 15975.
SE7706350L (sv)	1977-12-01	Antitumor -antibiotika
GB2002754A (en)	1979-02-28	Antitumor anthracycline antibiotics
ATE11142T1 (de)	1985-01-15	Herstellung von anthracyclinglycosiden.
ES8102590A1 (es)	1981-02-16	Metodo de producir antibioticos del tipo basado en streptomyces.
ZA884653B (en)	1989-03-29	Antitumor agent obtained by microbial stereoselective reduction of 4'-deoxy-4'-iododoxorubicin
FR2324310B1 (sv)	1981-11-13
ATE18233T1 (de)	1986-03-15	De-(mycinosyloxy)-tylosin-derivate.
NZ184320A (en)	1979-06-08	Neoviridogriseins 1,iiandiii from the culture of streptomyces sp' atcc 31289
SE8304132D0 (sv)	1983-07-25	Antitumor-antibiotikum
ES461702A1 (es)	1978-05-01	Procedimiento para la preparacion de una nueva sustancia an-tibiotica.
ES531043A0 (es)	1985-06-16	Un procedimiento para la preparacion de una macrolida.
NZ180036A (en)	1979-10-25	Aminocylitol antibiotics preparation by culturing micromonspora pur purea atcc 31,119 or 31,164 with aminocylcitol or cyclitol derivative
FR2024316B1 (sv)	1973-07-13
DK462281A (da)	1982-04-26	Fremgangsmaade til fremstilling af antibiotikum s/433
IE790991L (en)	1979-11-25	Antibiotic produced by cultivating streptomyces species¹nrrl 11298
ES332783A1 (es)	1967-12-01	Un procedimiento para aumentar el rendimiento de la tilosina producida por fermentacion.