SE7714464L - Glykosider och forfarande for framstellning derav - Google Patents

Glykosider och forfarande for framstellning derav

Info

Publication number: SE7714464L
Authority: SE; Sweden
Prior art keywords: glycosides; procedures; preparation; image; aglycone
Prior art date: 1976-12-22

Application number

SE7714464A

Other languages

English (en)

Other versions

SE437992B (sv

Inventor

G Cassinelli

F Arcamone

Marco A Di

Original Assignee

Farmaceutici Italia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-12-22

Filing date

1977-12-19

Publication date

1978-06-23

1977-12-19 Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia

1978-06-23 Publication of SE7714464L publication Critical patent/SE7714464L/sv

1985-03-25 Publication of SE437992B publication Critical patent/SE437992B/sv

Links

229930182470 glycoside Natural products 0.000 title abstract 2
150000002338 glycosides Chemical class 0.000 title abstract 2
238000000034 method Methods 0.000 title 1
TWCMVXMQHSVIOJ-UHFFFAOYSA-N Aglycone of yadanzioside D Natural products COC(=O)C12OCC34C(CC5C(=CC(O)C(O)C5(C)C3C(O)C1O)C)OC(=O)C(OC(=O)C)C24 TWCMVXMQHSVIOJ-UHFFFAOYSA-N 0.000 abstract 1
PLMKQQMDOMTZGG-UHFFFAOYSA-N Astrantiagenin E-methylester Natural products CC12CCC(O)C(C)(CO)C1CCC1(C)C2CC=C2C3CC(C)(C)CCC3(C(=O)OC)CCC21C PLMKQQMDOMTZGG-UHFFFAOYSA-N 0.000 abstract 1
239000003242 anti bacterial agent Substances 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
229940088710 antibiotic agent Drugs 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
PFOARMALXZGCHY-UHFFFAOYSA-N homoegonol Natural products C1=C(OC)C(OC)=CC=C1C1=CC2=CC(CCCO)=CC(OC)=C2O1 PFOARMALXZGCHY-UHFFFAOYSA-N 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Crystallography & Structural Chemistry (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SE7714464A 1976-12-22 1977-12-19 Forfarande for framstellning av 4-0-metylderivat av antracyklinglykosider SE437992B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB53454/76A GB1550879A (en)	1976-12-22	1976-12-22	Antitumour glycosides

Publications (2)

Publication Number	Publication Date
SE7714464L true SE7714464L (sv)	1978-06-23
SE437992B SE437992B (sv)	1985-03-25

Family

ID=10467870

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7714464A SE437992B (sv)	1976-12-22	1977-12-19	Forfarande for framstellning av 4-0-metylderivat av antracyklinglykosider

Country Status (24)

Country	Link
US (1)	US4183919A (sv)
JP (1)	JPS5379851A (sv)
AT (1)	AT354629B (sv)
AU (1)	AU518244B2 (sv)
BE (1)	BE862102A (sv)
CA (1)	CA1090788A (sv)
CH (1)	CH632770A5 (sv)
CS (1)	CS198280B2 (sv)
DE (1)	DE2757102C2 (sv)
DK (1)	DK148098C (sv)
FI (1)	FI63419C (sv)
FR (1)	FR2375252A1 (sv)
GB (1)	GB1550879A (sv)
GR (1)	GR70040B (sv)
HU (1)	HU176957B (sv)
IE (1)	IE45951B1 (sv)
IL (1)	IL53635A (sv)
NL (1)	NL7713850A (sv)
NO (1)	NO145163C (sv)
NZ (1)	NZ186047A (sv)
SE (1)	SE437992B (sv)
SU (1)	SU797583A3 (sv)
YU (1)	YU301177A (sv)
ZA (1)	ZA777555B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4265885A (en) *	1978-10-25	1981-05-05	Farmitalia Carlo Erba S.P.A.	Anthracyclines containing branched-chain amino-deoxy sugars
US4254110A (en) *	1979-02-02	1981-03-03	Farmitalia Carlo Erba S.P.A.	Pentofuranosyl anthracyclines, intermediates in and method for their preparation and compositions and use thereof
NL8001417A (nl) *	1979-03-17	1980-09-19	Erba Farmitalia	Antitumorglycosiden.
BE883759A (fr) *	1979-06-16	1980-10-01	Erba Farmitalia	Glycosides d'anthracycline
ATE4387T1 (de) *	1979-07-04	1983-08-15	Farmitalia Carlo Erba S.P.A.	Anthracyclin-glycoside, verfahren zu ihrer herstellung und sie enthaltende therapeutische zusammensetzung.
DE3100968A1 (de) *	1980-01-16	1982-01-14	Farmitalia Carlo Erba S.p.A., 20159 Milano	Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CA1248944A (en) *	1982-09-28	1989-01-17	Gareth J. Thomas	Anthracycline glycosides
WO2007075092A1 (en) *	2005-12-29	2007-07-05	Instytut Biochemii I Biofizyki	New derivatives of epirubicin, their medicinal application and pharmaceuticals acceptable forms of drugs
WO2007075094A1 (en) *	2005-12-27	2007-07-05	Instytut Biochemii I Biofizyki	New derivatives of epirubicin, their medicinal application and pharmaceuticaly acceptable forms of drugs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1506200A (en) *	1975-04-30	1978-04-05	Farmaceutici Italia	Glycosides
US3976667A (en) *	1975-06-19	1976-08-24	The Upjohn Company	Steffimycinone, 7-deoxysteffimycinone and derivatives
GB1511559A (en) *	1975-09-26	1978-05-24	Farmaceutici Italia	Anthracycline glycosides

1976
- 1976-12-22 GB GB53454/76A patent/GB1550879A/en not_active Expired
1977
- 1977-12-14 NL NL7713850A patent/NL7713850A/xx not_active Application Discontinuation
- 1977-12-14 US US05/860,447 patent/US4183919A/en not_active Expired - Lifetime
- 1977-12-19 IE IE2579/77A patent/IE45951B1/en unknown
- 1977-12-19 NO NO774370A patent/NO145163C/no unknown
- 1977-12-19 FR FR7738201A patent/FR2375252A1/fr active Granted
- 1977-12-19 IL IL53635A patent/IL53635A/xx unknown
- 1977-12-19 GR GR55011A patent/GR70040B/el unknown
- 1977-12-19 AT AT907377A patent/AT354629B/de not_active IP Right Cessation
- 1977-12-19 AU AU31748/77A patent/AU518244B2/en not_active Expired
- 1977-12-19 DK DK564777A patent/DK148098C/da not_active IP Right Cessation
- 1977-12-19 SE SE7714464A patent/SE437992B/sv not_active IP Right Cessation
- 1977-12-19 FI FI773822A patent/FI63419C/fi not_active IP Right Cessation
- 1977-12-19 YU YU03011/77A patent/YU301177A/xx unknown
- 1977-12-20 NZ NZ186047A patent/NZ186047A/xx unknown
- 1977-12-20 ZA ZA00777555A patent/ZA777555B/xx unknown
- 1977-12-20 CS CS778604A patent/CS198280B2/cs unknown
- 1977-12-21 BE BE183664A patent/BE862102A/xx not_active IP Right Cessation
- 1977-12-21 CH CH1580877A patent/CH632770A5/de not_active IP Right Cessation
- 1977-12-21 CA CA293,545A patent/CA1090788A/en not_active Expired
- 1977-12-21 DE DE2757102A patent/DE2757102C2/de not_active Expired
- 1977-12-21 JP JP15424677A patent/JPS5379851A/ja active Granted
- 1977-12-22 HU HU77FA999A patent/HU176957B/hu unknown
1979
- 1979-06-18 SU SU792778651A patent/SU797583A3/ru active

Also Published As

Publication number	Publication date
DK148098B (da)	1985-03-04
BE862102A (fr)	1978-06-21
ZA777555B (en)	1978-09-27
IE45951B1 (en)	1983-01-12
JPS5379851A (en)	1978-07-14
CS198280B2 (en)	1980-05-30
DE2757102A1 (de)	1978-07-06
AT354629B (de)	1979-01-25
ATA907377A (de)	1979-06-15
IL53635A (en)	1981-03-31
FI63419B (fi)	1983-02-28
YU301177A (en)	1982-06-30
CH632770A5 (de)	1982-10-29
IE45951L (en)	1978-06-22
NO145163B (no)	1981-10-19
HU176957B (hu)	1981-06-28
NZ186047A (en)	1979-06-19
GB1550879A (en)	1979-08-22
US4183919A (en)	1980-01-15
DE2757102C2 (de)	1986-06-19
SU797583A3 (ru)	1981-01-15
JPS6134437B2 (sv)	1986-08-07
FR2375252B1 (sv)	1980-08-22
FI63419C (fi)	1983-06-10
AU518244B2 (en)	1981-09-24
NL7713850A (nl)	1978-06-26
FI773822A7 (fi)	1978-06-23
GR70040B (sv)	1982-07-26
AU3174877A (en)	1979-06-28
IL53635A0 (en)	1978-03-10
DK148098C (da)	1985-07-29
SE437992B (sv)	1985-03-25
FR2375252A1 (fr)	1978-07-21
CA1090788A (en)	1980-12-02
NO145163C (no)	1982-01-27
NO774370L (no)	1978-06-23
DK564777A (da)	1978-06-23

Legal Events

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 7714464-0

Effective date: 19901019

Format of ref document f/p: F

Publication	Publication Date	Title
ES435833A1 (es)	1976-12-01	Un procedimiento para la sintesis de glicosidos de adriami-cinona.
US4345068A (en)	1982-08-17	Process for the preparation of 4'-epidaunorubicin, 3',4'-diepidaunorubicin, their doxorubicin analogs, and intermediates used in said process
ES424457A1 (es)	1976-12-16	Procedimiento para la preparacion de derivados de 9-beta-d-arabino furanosil nucleotidos.
Ingaki et al.	1972	Lignans of Trachelospermum asiaticum var. intermedium. I. Isolation and structures of arctiin, matairesinoside and tracheloside
SE8203274L (sv)	1982-11-29	Antracykliner och forfarande for deras framstellning
ES8101622A1 (es)	1980-12-16	Un procedimiento para la produccion de un derivado de antra-ciclina
FR2399439A1 (fr)	1979-03-02	Anthracyclines antibiotiques contre les tumeurs
IE45951L (en)	1978-06-22	Antitumour glycosides
IT1201937B (it)	1989-02-02	Glucosidi antraciclinonici
De Tommasi et al.	1997	Flavonol and chalcone ester glycosides from Bidens leucantha
PT85056B (pt)	1990-03-30	Processo para a preparacao de novos derivados glicosidicos de antraciclina e de composicoes farmaceuticas que os contem
ES2007419A6 (es)	1989-06-16	Un procedimiento para la preparacion de un glicosido de antraciclina.
SE7708060L (sv)	1978-01-14	Antracykliner
Nakagawa et al.	1982	A new disaccharide, glaucobiose from Chinese drug “Pai-ch'ien”: A comparison of 13C NMR with its diastereomeric isomer, strophanthobiose
PT68117A (fr)	1978-06-01	Nouveau procede de preparation de derives de glycosides benzopyranniques
GB1532551A (en)	1978-11-15	Furo(3,4-6)furone derivatives and their preparation
SE7708452L (sv)	1979-01-23	Komposition innehallande en antrakinonforening
SE8002031L (sv)	1980-09-18	Antitumorglykosider
SE8804037D0 (sv)	1988-11-08	Nya 4-demetoxiantracyclinderivat
SE7711105L (sv)	1978-04-28	Sett att framstella nya 17-spirosultinderivat och motsvarande gamma-hydroxisyror
SE8302517L (sv)	1983-05-03	Forfarande for framstellning av antibiotikum c-15003 p-0 (maytansinol)
JPS5634695A (en)	1981-04-06	Novel anthracycline derivative and its preparation
Brazhnikova et al.	1976	Stereochemistry of the antibiotic carminomycin
JPS5470290A (en)	1979-06-05	Erythromycin a derivative and its preparation
JPS55108890A (en)	1980-08-21	Aklavin derivative and its preparation