SE8003122L - Kinazolinderivat med antihypertensiv aktivitet - Google Patents

Kinazolinderivat med antihypertensiv aktivitet

Info

Publication number: SE8003122L
Authority: SE; Sweden
Prior art keywords: derivatives; amino; compounds; piperazino; antihypertensive activity
Prior art date: 1979-04-25

Application number

SE8003122A

Other languages

English (en)

Other versions

SE435061B (sv

Inventor

S F Campbell

G Fiars

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-04-25

Filing date

1980-04-24

Publication date

1980-10-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10504770&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE8003122(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1980-04-24 Application filed by Pfizer filed Critical Pfizer

1980-10-26 Publication of SE8003122L publication Critical patent/SE8003122L/sv

1984-09-03 Publication of SE435061B publication Critical patent/SE435061B/sv

Links

230000003276 anti-hypertensive effect Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
UDETZZKGDGINOX-UHFFFAOYSA-N [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(3,4-dihydro-2h-chromen-2-yl)methanone Chemical compound C1CC2=CC=CC=C2OC1C(=O)N(CC1)CCN1C1=NC(N)=C(C=C(C(OC)=C2)OC)C2=N1 UDETZZKGDGINOX-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
229940030600 antihypertensive agent Drugs 0.000 abstract 1
239000002220 antihypertensive agent Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000004193 piperazinyl group Chemical group 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
150000003246 quinazolines Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000007858 starting material Substances 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

SE8003122A 1979-04-25 1980-04-24 4-amino-6,7-dialkoxikinazolinforening och farmaceutisk beredning for behandling av hypertension SE435061B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB7914431		1979-04-25

Publications (2)

Publication Number	Publication Date
SE8003122L true SE8003122L (sv)	1980-10-26
SE435061B SE435061B (sv)	1984-09-03

Family

ID=10504770

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8003122A SE435061B (sv)	1979-04-25	1980-04-24	4-amino-6,7-dialkoxikinazolinforening och farmaceutisk beredning for behandling av hypertension

Country Status (33)

Country	Link
US (1)	US4279910A (sv)
JP (1)	JPS55145684A (sv)
KR (1)	KR830002567B1 (sv)
AR (1)	AR224400A1 (sv)
AT (1)	AT373596B (sv)
BE (1)	BE882967A (sv)
CA (1)	CA1132558A (sv)
CH (1)	CH642076A5 (sv)
CS (1)	CS209950B2 (sv)
DD (1)	DD150202A5 (sv)
DE (1)	DE3015676A1 (sv)
DK (1)	DK121080A (sv)
EG (1)	EG14651A (sv)
ES (1)	ES8101588A1 (sv)
FI (1)	FI64592C (sv)
FR (1)	FR2455042A1 (sv)
GB (1)	GB2049683B (sv)
GR (1)	GR68049B (sv)
HU (1)	HU184747B (sv)
IE (1)	IE49705B1 (sv)
IL (1)	IL59900A (sv)
IT (1)	IT1141490B (sv)
LU (1)	LU82394A1 (sv)
NL (1)	NL182563C (sv)
NO (1)	NO152508C (sv)
NZ (1)	NZ193511A (sv)
PH (1)	PH15156A (sv)
PL (1)	PL121470B1 (sv)
PT (1)	PT71139A (sv)
SE (1)	SE435061B (sv)
SU (1)	SU915804A3 (sv)
YU (1)	YU41709B (sv)
ZA (1)	ZA802488B (sv)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3511836A (en) *	1967-12-13	1970-05-12	Pfizer & Co C	2,4,6,7-tetra substituted quinazolines
US3635979A (en) *	1969-09-29	1972-01-18	Pfizer	Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines
US4026894A (en) *	1975-10-14	1977-05-31	Abbott Laboratories	Antihypertensive agents
US4001237A (en) *	1976-02-18	1977-01-04	Bristol-Myers Company	Oxazole, isoxazole, thiazole and isothiazole amides
US4140776A (en) *	1977-09-16	1979-02-20	Merck & Co., Inc.	N-pyrazinecarbonyl-N'-acylguanidines
GB2007656B (en) *	1977-11-05	1982-05-19	Pfizer Ltd	Therapeutic agents

1980
- 1980-03-20 DK DK121080A patent/DK121080A/da not_active IP Right Cessation
- 1980-04-15 US US06/140,534 patent/US4279910A/en not_active Expired - Lifetime
- 1980-04-16 CS CS802656A patent/CS209950B2/cs unknown
- 1980-04-19 GR GR61722A patent/GR68049B/el unknown
- 1980-04-22 EG EG80247A patent/EG14651A/xx active
- 1980-04-23 IL IL59900A patent/IL59900A/xx unknown
- 1980-04-23 FI FI801306A patent/FI64592C/fi not_active IP Right Cessation
- 1980-04-23 AR AR280773A patent/AR224400A1/es active
- 1980-04-23 NZ NZ193511A patent/NZ193511A/xx unknown
- 1980-04-23 IT IT21598/80A patent/IT1141490B/it active
- 1980-04-23 DE DE19803015676 patent/DE3015676A1/de not_active Ceased
- 1980-04-23 LU LU82394A patent/LU82394A1/fr unknown
- 1980-04-23 AT AT0218980A patent/AT373596B/de not_active IP Right Cessation
- 1980-04-24 FR FR8009235A patent/FR2455042A1/fr active Granted
- 1980-04-24 NO NO801196A patent/NO152508C/no unknown
- 1980-04-24 ZA ZA00802488A patent/ZA802488B/xx unknown
- 1980-04-24 CH CH317280A patent/CH642076A5/de not_active IP Right Cessation
- 1980-04-24 CA CA350,598A patent/CA1132558A/en not_active Expired
- 1980-04-24 NL NLAANVRAGE8002387,A patent/NL182563C/xx not_active IP Right Cessation
- 1980-04-24 GB GB8013543A patent/GB2049683B/en not_active Expired
- 1980-04-24 YU YU1131/80A patent/YU41709B/xx unknown
- 1980-04-24 DD DD80220686A patent/DD150202A5/de unknown
- 1980-04-24 PT PT71139A patent/PT71139A/pt unknown
- 1980-04-24 PH PH23945A patent/PH15156A/en unknown
- 1980-04-24 SE SE8003122A patent/SE435061B/sv not_active IP Right Cessation
- 1980-04-24 BE BE0/200366A patent/BE882967A/fr not_active IP Right Cessation
- 1980-04-24 ES ES490867A patent/ES8101588A1/es not_active Expired
- 1980-04-24 HU HU801016A patent/HU184747B/hu unknown
- 1980-04-24 JP JP5485980A patent/JPS55145684A/ja active Granted
- 1980-04-24 IE IE827/80A patent/IE49705B1/en unknown
- 1980-04-24 SU SU802912149A patent/SU915804A3/ru active
- 1980-04-25 KR KR1019800001676A patent/KR830002567B1/ko not_active Expired
- 1980-04-25 PL PL1980223755A patent/PL121470B1/pl unknown

Also Published As

Publication number	Publication date
IE49705B1 (en)	1985-11-27
ZA802488B (en)	1981-08-26
IT8021598A0 (it)	1980-04-23
FI801306A7 (fi)	1980-10-26
FR2455042A1 (fr)	1980-11-21
PH15156A (en)	1982-08-24
PL121470B1 (en)	1982-05-31
GR68049B (sv)	1981-10-29
BE882967A (fr)	1980-10-24
SU915804A3 (en)	1982-03-23
NO152508C (no)	1985-10-09
HU184747B (en)	1984-10-29
KR830002758A (ko)	1983-06-30
EG14651A (en)	1985-03-31
IE800827L (en)	1980-10-25
ATA218980A (de)	1983-06-15
ES490867A0 (es)	1980-12-16
PL223755A1 (sv)	1981-02-13
CH642076A5 (de)	1984-03-30
YU113180A (en)	1983-02-28
NZ193511A (en)	1982-03-30
IT1141490B (it)	1986-10-01
FI64592C (fi)	1983-12-12
IL59900A (en)	1983-11-30
NO152508B (no)	1985-07-01
FI64592B (fi)	1983-08-31
GB2049683A (en)	1980-12-31
FR2455042B1 (sv)	1983-05-20
IL59900A0 (en)	1980-06-30
AR224400A1 (es)	1981-11-30
NO801196L (no)	1980-10-27
DE3015676A1 (de)	1980-11-13
CA1132558A (en)	1982-09-28
YU41709B (en)	1987-12-31
KR830002567B1 (ko)	1983-11-14
ES8101588A1 (es)	1980-12-16
JPS5738591B2 (sv)	1982-08-16
NL182563C (nl)	1988-04-05
PT71139A (en)	1980-05-01
JPS55145684A (en)	1980-11-13
SE435061B (sv)	1984-09-03
US4279910A (en)	1981-07-21
LU82394A1 (fr)	1980-07-31
DD150202A5 (de)	1981-08-19
AT373596B (de)	1984-02-10
NL182563B (nl)	1987-11-02
DK121080A (da)	1980-10-26
NL8002387A (nl)	1980-10-28
CS209950B2 (en)	1981-12-31
GB2049683B (en)	1983-01-26

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Legal Events

Date

Code

Title

Description

1995-01-31

NUG

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