SE8003676L - Mellanprodukter for framstellning av biologiskt aktiva 6-substituerade penicillansyror - Google Patents

Mellanprodukter for framstellning av biologiskt aktiva 6-substituerade penicillansyror

Info

Publication number: SE8003676L
Authority: SE; Sweden
Prior art keywords: substituted; penicillan; intermediates; acids; preparation
Prior art date: 1979-05-19

Application number

SE8003676A

Other languages

English (en)

Other versions

SE449995B (sv

Inventor

J E G Kemp

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-05-19

Filing date

1980-05-16

Publication date

1980-11-20

1980-05-16 Application filed by Pfizer filed Critical Pfizer

1980-11-20 Publication of SE8003676L publication Critical patent/SE8003676L/sv

1987-06-01 Publication of SE449995B publication Critical patent/SE449995B/sv

Links

239000002253 acid Substances 0.000 title 1
150000007513 acids Chemical class 0.000 title 1
239000000543 intermediate Substances 0.000 title 1
229930182555 Penicillin Natural products 0.000 abstract 1
-1 azide ions Chemical class 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
238000006073 displacement reaction Methods 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
230000000269 nucleophilic effect Effects 0.000 abstract 1
RBKMMJSQKNKNEV-RITPCOANSA-N penicillanic acid Chemical class OC(=O)[C@H]1C(C)(C)S[C@@H]2CC(=O)N21 RBKMMJSQKNKNEV-RITPCOANSA-N 0.000 abstract 1
229940049954 penicillin Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/28—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with modified 2-carboxyl group
- C07D499/32—Esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/04—Preparation
- C07D499/10—Modification of an amino radical directly attached in position 6
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SE8003676A 1979-05-19 1980-05-16 6-perhalogenalkylsulfonyloxipenicillansyraderivat samt forfarande for framstellning derav SE449995B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB7917505		1979-05-19

Publications (2)

Publication Number	Publication Date
SE8003676L true SE8003676L (sv)	1980-11-20
SE449995B SE449995B (sv)	1987-06-01

Family

ID=10505288

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8003676A SE449995B (sv)	1979-05-19	1980-05-16	6-perhalogenalkylsulfonyloxipenicillansyraderivat samt forfarande for framstellning derav

Country Status (28)

Country	Link
US (1)	US4356122A (sv)
JP (1)	JPS5941994B2 (sv)
KR (1)	KR840000079B1 (sv)
AR (1)	AR225038A1 (sv)
AT (1)	AT366694B (sv)
AU (1)	AU517488B2 (sv)
BE (1)	BE883319A (sv)
CA (1)	CA1140916A (sv)
CH (1)	CH650262A5 (sv)
CS (1)	CS214756B2 (sv)
DD (1)	DD151310A5 (sv)
DE (1)	DE3018847C2 (sv)
DK (1)	DK155180A (sv)
ES (1)	ES8105737A1 (sv)
FI (1)	FI71562C (sv)
FR (1)	FR2457293A1 (sv)
GR (1)	GR68461B (sv)
IE (1)	IE49804B1 (sv)
IL (1)	IL60097A (sv)
IT (1)	IT1140946B (sv)
LU (1)	LU82458A1 (sv)
NL (1)	NL180937C (sv)
NO (1)	NO801473L (sv)
PH (1)	PH15033A (sv)
PL (1)	PL224188A1 (sv)
PT (1)	PT71253A (sv)
SE (1)	SE449995B (sv)
ZA (1)	ZA802908B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA803742B (en) *	1979-07-02	1981-06-24	Beecham Group Ltd	Penicillanic acid derivatives, their preparation and use
JPS6034969A (ja) *	1983-08-08	1985-02-22	Toyama Chem Co Ltd	新規なペニシラン酸誘導体およびその塩類
CA3056681A1 (en) *	2017-03-23	2018-09-27	Trucode Gene Repair, Inc.	Peptide nucleic acid (pna) monomers with an orthogonally protected ester moiety

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5749555B2 (sv) *	1973-04-04	1982-10-22
US4282149A (en) *	1977-03-21	1981-08-04	Massachusetts Institute Of Technology	Carbon and oxygen analogs of penicillin
US4265882A (en) *	1977-10-03	1981-05-05	Massachusetts Institute Of Technology	Sulphur analogs of penicillins having a nucleophile substituted in the 6 and 7 position, respectively

1980
- 1980-04-10 DK DK155180A patent/DK155180A/da not_active IP Right Cessation
- 1980-05-13 PL PL22418880A patent/PL224188A1/xx unknown
- 1980-05-14 BE BE0/200635A patent/BE883319A/fr unknown
- 1980-05-14 CS CS803351A patent/CS214756B2/cs unknown
- 1980-05-14 AT AT0259780A patent/AT366694B/de not_active IP Right Cessation
- 1980-05-15 GR GR61960A patent/GR68461B/el unknown
- 1980-05-15 FI FI801581A patent/FI71562C/sv not_active IP Right Cessation
- 1980-05-15 CA CA000352042A patent/CA1140916A/en not_active Expired
- 1980-05-15 KR KR1019800001920A patent/KR840000079B1/ko not_active Expired
- 1980-05-16 DE DE3018847A patent/DE3018847C2/de not_active Expired
- 1980-05-16 NL NLAANVRAGE8002843,A patent/NL180937C/xx not_active IP Right Cessation
- 1980-05-16 PH PH24036A patent/PH15033A/en unknown
- 1980-05-16 IT IT22104/80A patent/IT1140946B/it active
- 1980-05-16 ZA ZA00802908A patent/ZA802908B/xx unknown
- 1980-05-16 IE IE1024/80A patent/IE49804B1/en unknown
- 1980-05-16 DD DD80221165A patent/DD151310A5/de unknown
- 1980-05-16 IL IL60097A patent/IL60097A/xx unknown
- 1980-05-16 CH CH3844/80A patent/CH650262A5/de not_active IP Right Cessation
- 1980-05-16 FR FR8011063A patent/FR2457293A1/fr active Granted
- 1980-05-16 AU AU58468/80A patent/AU517488B2/en not_active Ceased
- 1980-05-16 SE SE8003676A patent/SE449995B/sv not_active IP Right Cessation
- 1980-05-16 AR AR281078A patent/AR225038A1/es active
- 1980-05-16 NO NO801473A patent/NO801473L/no unknown
- 1980-05-16 PT PT71253A patent/PT71253A/pt unknown
- 1980-05-17 JP JP55065859A patent/JPS5941994B2/ja not_active Expired
- 1980-05-19 ES ES491612A patent/ES8105737A1/es not_active Expired
- 1980-05-19 LU LU82458A patent/LU82458A1/fr unknown
- 1980-12-10 US US06/214,846 patent/US4356122A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NO801473L (no)	1980-11-20
DE3018847C2 (de)	1982-09-30
PL224188A1 (sv)	1981-02-13
JPS55157588A (en)	1980-12-08
IL60097A0 (en)	1980-07-31
ZA802908B (en)	1981-05-27
CH650262A5 (de)	1985-07-15
PT71253A (en)	1980-06-01
JPS5941994B2 (ja)	1984-10-11
CS214756B2 (en)	1982-05-28
ES491612A0 (es)	1981-05-16
CA1140916A (en)	1983-02-08
KR830002769A (ko)	1983-05-30
GR68461B (sv)	1981-12-30
SE449995B (sv)	1987-06-01
IT1140946B (it)	1986-10-10
DD151310A5 (de)	1981-10-14
ES8105737A1 (es)	1981-05-16
FI71562B (fi)	1986-10-10
AR225038A1 (es)	1982-02-15
PH15033A (en)	1982-05-20
US4356122A (en)	1982-10-26
KR840000079B1 (ko)	1984-02-08
ATA259780A (de)	1981-09-15
AU5846880A (en)	1980-11-27
AU517488B2 (en)	1981-08-06
LU82458A1 (fr)	1980-10-08
AT366694B (de)	1982-04-26
IE801024L (en)	1980-11-19
DE3018847A1 (de)	1980-12-11
FI801581A7 (fi)	1980-11-20
NL180937C (nl)	1987-05-18
IE49804B1 (en)	1985-12-25
IT8022104A0 (it)	1980-05-16
FR2457293A1 (fr)	1980-12-19
FI71562C (sv)	1987-01-19
NL180937B (nl)	1986-12-16
FR2457293B1 (sv)	1983-05-20
NL8002843A (nl)	1980-11-21
IL60097A (en)	1983-02-23
BE883319A (fr)	1980-11-14
DK155180A (da)	1980-11-20

Legal Events

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 8003676-7

Effective date: 19900518

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IE801024L (en)	1980-11-19	6-haloalkylsulphonyloxy penicillanic acid derivatives
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