SE8007121L - OXYOHIMBANKARBOXYLIC ACID DERIVATIVE - Google Patents
OXYOHIMBANKARBOXYLIC ACID DERIVATIVEInfo
- Publication number
- SE8007121L SE8007121L SE8007121A SE8007121A SE8007121L SE 8007121 L SE8007121 L SE 8007121L SE 8007121 A SE8007121 A SE 8007121A SE 8007121 A SE8007121 A SE 8007121A SE 8007121 L SE8007121 L SE 8007121L
- Authority
- SE
- Sweden
- Prior art keywords
- radical
- alkoxy
- carbon atoms
- oxyohimbankarboxylic
- acid derivative
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 206010000117 Abnormal behaviour Diseases 0.000 abstract 1
- 208000012886 Vertigo Diseases 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- GRTOGORTSDXSFK-XJTZBENFSA-N ajmalicine Chemical compound C1=CC=C2C(CCN3C[C@@H]4[C@H](C)OC=C([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 GRTOGORTSDXSFK-XJTZBENFSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000005078 alkoxycarbonylalkyl group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000005112 cycloalkylalkoxy group Chemical group 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 230000001037 epileptic effect Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- BLNWTAHYTCHDJH-UHFFFAOYSA-O hydroxy(oxo)azanium Chemical compound O[NH+]=O BLNWTAHYTCHDJH-UHFFFAOYSA-O 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- ZLQMRLSBXKQKMG-UHFFFAOYSA-N rauniticine Natural products COC(=O)C1=CC2CC3N(CCc4c3[nH]c5ccccc45)CC2C(C)O1 ZLQMRLSBXKQKMG-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 231100000889 vertigo Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Polyesters Or Polycarbonates (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Oxayohimbane derivatives of the formula <IMAGE> in which R1 is a hydrogen, alkoxycarbonyl, alkoxycarbonylalkyl or alkylcarbonyl or a phenoxycarbonyl radical in which the phenyl radical thereof is unsubstituted or is substituted by a halogen atom or a nitro radical and R2 is a hydroxyl or OM radical, M representing an alkali metal or alkaline earth metal, or is an alkoxy, cycloalkylalkoxy, cycloalkoxy, -NH2, alkylamino, dialkylamino or cycloalkylamino radical, with the exception of the compounds in which simultaneously R1 is H and R2 is CH3O or OH, in which definitions alkoxy and alkyl have from 1 to 4 carbon atoms, and cycloalkyl has from 3 to 6 carbon atoms, and their pharmaceutically acceptable acid addition salts, which are useful in therapy for combatting behavioural disorders and epileptic vertigo, can be prepared from raubasine by known methods.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7925353A FR2467206A1 (en) | 1979-10-11 | 1979-10-11 | OXAYOHIMBANE-CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE8007121L true SE8007121L (en) | 1981-04-12 |
Family
ID=9230588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8007121A SE8007121L (en) | 1979-10-11 | 1980-10-10 | OXYOHIMBANKARBOXYLIC ACID DERIVATIVE |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS5661382A (en) |
| AU (1) | AU6316580A (en) |
| BE (1) | BE885656A (en) |
| DE (1) | DE3038401A1 (en) |
| DK (1) | DK428780A (en) |
| ES (1) | ES8206521A1 (en) |
| FR (1) | FR2467206A1 (en) |
| GB (1) | GB2060639A (en) |
| GR (1) | GR70751B (en) |
| IL (1) | IL61246A0 (en) |
| IT (1) | IT1195761B (en) |
| LU (1) | LU82833A1 (en) |
| NL (1) | NL8005609A (en) |
| NO (1) | NO803038L (en) |
| PT (1) | PT71901B (en) |
| SE (1) | SE8007121L (en) |
| ZA (1) | ZA806246B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4125137C2 (en) * | 1991-07-30 | 1995-06-14 | Icos Ges Fuer Ind Communicatio | Control panel for processing and measuring machines |
-
1979
- 1979-10-11 FR FR7925353A patent/FR2467206A1/en active Granted
-
1980
- 1980-10-09 JP JP14184380A patent/JPS5661382A/en active Pending
- 1980-10-09 IT IT25251/80A patent/IT1195761B/en active
- 1980-10-09 ZA ZA00806246A patent/ZA806246B/en unknown
- 1980-10-10 IL IL61246A patent/IL61246A0/en unknown
- 1980-10-10 GB GB8032835A patent/GB2060639A/en not_active Withdrawn
- 1980-10-10 AU AU63165/80A patent/AU6316580A/en not_active Abandoned
- 1980-10-10 GR GR63108A patent/GR70751B/el unknown
- 1980-10-10 LU LU82833A patent/LU82833A1/en unknown
- 1980-10-10 NL NL8005609A patent/NL8005609A/en not_active Application Discontinuation
- 1980-10-10 BE BE0/202429A patent/BE885656A/en unknown
- 1980-10-10 SE SE8007121A patent/SE8007121L/en not_active Application Discontinuation
- 1980-10-10 NO NO803038A patent/NO803038L/en unknown
- 1980-10-10 ES ES495797A patent/ES8206521A1/en not_active Expired
- 1980-10-10 DE DE19803038401 patent/DE3038401A1/en not_active Withdrawn
- 1980-10-10 PT PT71901A patent/PT71901B/en unknown
- 1980-10-10 DK DK428780A patent/DK428780A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL8005609A (en) | 1981-04-14 |
| GB2060639A (en) | 1981-05-07 |
| DK428780A (en) | 1981-04-12 |
| FR2467206B1 (en) | 1983-01-28 |
| PT71901B (en) | 1981-08-31 |
| DE3038401A1 (en) | 1981-04-23 |
| IT1195761B (en) | 1988-10-27 |
| ZA806246B (en) | 1981-10-28 |
| BE885656A (en) | 1981-04-10 |
| JPS5661382A (en) | 1981-05-26 |
| ES495797A0 (en) | 1982-01-16 |
| IT8025251A0 (en) | 1980-10-09 |
| ES8206521A1 (en) | 1982-01-16 |
| GR70751B (en) | 1983-03-14 |
| PT71901A (en) | 1980-11-01 |
| IL61246A0 (en) | 1980-12-31 |
| AU6316580A (en) | 1981-04-16 |
| LU82833A1 (en) | 1982-05-10 |
| NO803038L (en) | 1981-04-13 |
| FR2467206A1 (en) | 1981-04-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE8101409L (en) | CARBOSTYRIL DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF | |
| ES514053A0 (en) | "PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF QUINOLEIN". | |
| ES8104321A1 (en) | Alkyl-ketohexopyrand-side derivatives and method of use | |
| RO93855A (en) | PROCESS FOR PREPARATION OF ARILCICLOBUTILALCILLAMINE | |
| SE8000245L (en) | Means against Glaucoma | |
| SE8304071L (en) | NEW PIPERAZINE DERIVATIVES | |
| SE8007121L (en) | OXYOHIMBANKARBOXYLIC ACID DERIVATIVE | |
| DK163055C (en) | METHOD OF ANALOGY FOR THE PREPARATION OF 2-DIPROPYLAMINO- (5 OR 7) -FORMYLAMINO-6-HYDROXY-1,2,3,4-TETRAHYDRONAPHTHAL AND PHARMACOLOGICAL ACCEPTABLE ACID ADDITION SALTS. | |
| YU310580A (en) | Process for obtaining new benzothiazole derivatives | |
| SE7703000L (en) | PROCEDURE FOR THE PREPARATION OF CARBOSTYRIL DERIVATIVES | |
| IE781377L (en) | 2, 4-diamino-5-benzyl pyrimidines | |
| AU546260B2 (en) | Diphenylbutyl-1-acylpiperazines | |
| ES8500953A1 (en) | PROCEDURE FOR PREPARING DERIVATIVES OF TIENO-THIAZOLE | |
| ES472085A1 (en) | Pyranochromone derivatives and therapeutic composition comprising same for treatment of allergic diseases | |
| ES8101071A1 (en) | 2-(Pyrid-2-yl)tetrahydrothiophene derivatives | |
| ES472276A1 (en) | Cis-4a-phenyl-2,3,4,4a,5,6,7,7a-octahydro-1h-2-pyrindines and pharmaceutical compositions containing them | |
| AU544275B2 (en) | Triazololozuinazolinone derivatives | |
| ES518613A0 (en) | A PROCEDURE FOR PREPARING QUINOLYLACETIC ACID COMPOUNDS | |
| DK82583D0 (en) | FURYLOXAZOLYL ACETIC ACID DERIVATIVES AND PROCEDURES FOR PREPARING THEREOF | |
| SE7706693L (en) | METHODS OF PRODUCING HYDRAZINOPYRIDAZINE DERIVATIVES | |
| JPS5412376A (en) | Antibacterial derivative of pseudomonic acid | |
| AU551901B2 (en) | Substituted thienobenzodiazepinones | |
| SE8301785L (en) | SET TO MAKE 2-THIOPHENIC ACETIC ACID DERIVATIVES AND INTERMEDIATES REQUIRED FOR THEIR PREPARATION | |
| GR3002417T3 (en) | Derivatives of 8-phenylthiotetrahydroquinolines and their salts, their synthesis for use as medicaments and compositions containing them | |
| ES500108A0 (en) | PROCEDURE FOR PREPARING NEW BENZOTIOPYRAN (2,3-C) PI-RIDINAS |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 8007121-0 Format of ref document f/p: F |