SE8103003L - Terapeutisk forfarande for behandling av diabetes och farmaceutisk komposition for genomforande av forfarandet - Google Patents

Terapeutisk forfarande for behandling av diabetes och farmaceutisk komposition for genomforande av forfarandet

Info

Publication number: SE8103003L
Authority: SE; Sweden
Prior art keywords: procedure; carnitine; implementation; pharmaceutical composition; treating diabetes
Prior art date: 1980-05-15

Application number

SE8103003A

Other languages

English (en)

Swedish (sv)

Inventor

C Cavazza

Original Assignee

Ind Farmaceutiche Riunite Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-05-15

Filing date

1981-05-13

Publication date

1981-11-16

1981-05-13 Application filed by Ind Farmaceutiche Riunite Spa filed Critical Ind Farmaceutiche Riunite Spa

1981-11-16 Publication of SE8103003L publication Critical patent/SE8103003L/

Links

206010012601 diabetes mellitus Diseases 0.000 title 1
238000000034 method Methods 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
238000002560 therapeutic procedure Methods 0.000 title 1
PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 2
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
206010010071 Coma Diseases 0.000 abstract 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
102000004877 Insulin Human genes 0.000 abstract 1
108090001061 Insulin Proteins 0.000 abstract 1
206010023379 Ketoacidosis Diseases 0.000 abstract 1
208000007976 Ketosis Diseases 0.000 abstract 1
UFAHZIUFPNSHSL-MRVPVSSYSA-N O-propanoyl-L-carnitine Chemical compound CCC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C UFAHZIUFPNSHSL-MRVPVSSYSA-N 0.000 abstract 1
206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
-1 acyl L-carnitines Chemical class 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
239000008103 glucose Substances 0.000 abstract 1
229940125396 insulin Drugs 0.000 abstract 1
238000007911 parenteral administration Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin

Landscapes

Health & Medical Sciences (AREA)
Emergency Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

SE8103003A 1980-05-15 1981-05-13 Terapeutisk forfarande for behandling av diabetes och farmaceutisk komposition for genomforande av forfarandet SE8103003L (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT48692/80A IT1133010B (it)	1980-05-15	1980-05-15	Metodo terapuetico per il trattamento del diabete mellito a insorgenza giovanile e composizione farmaceutica per tale metodo

Publications (1)

Publication Number	Publication Date
SE8103003L true SE8103003L (sv)	1981-11-16

Family

ID=11268073

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8103003A SE8103003L (sv)	1980-05-15	1981-05-13	Terapeutisk forfarande for behandling av diabetes och farmaceutisk komposition for genomforande av forfarandet

Country Status (14)

Country	Link
US (1)	US4362719A ( )
JP (1)	JPS579721A ( )
AU (1)	AU540859B2 ( )
BE (1)	BE888797A ( )
CA (1)	CA1173749A ( )
CH (1)	CH654208A5 ( )
DE (1)	DE3119460A1 ( )
FR (1)	FR2482588B1 ( )
GB (1)	GB2075838B ( )
IE (1)	IE51224B1 ( )
IL (1)	IL62847A ( )
IT (1)	IT1133010B ( )
NL (1)	NL8102384A ( )
SE (1)	SE8103003L ( )

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1157238B (it) *	1982-10-29	1987-02-11	Sigma Tau Ind Farmaceuti	Impiego di 1-carnitina per migliorare i paramenti biochimici e comportamentali dell'eta' senile
IT1237343B (it) *	1984-03-28	1993-05-31	Francia Farma	Dicloridrato di acetildicarnitina, procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono
US4537772A (en) *	1984-05-02	1985-08-27	Merck & Co., Inc.	Enhancing absorption of drugs from gastrointestinal tract using acylcarnitines
US5545412A (en) *	1985-01-07	1996-08-13	Syntex (U.S.A.) Inc.	N-[1, (1-1)-dialkyloxy]-and N-[1, (1-1)-dialkenyloxy]-alk-1-yl-n,n,n-tetrasubstituted ammonium lipids and uses therefor
US4897355A (en) *	1985-01-07	1990-01-30	Syntex (U.S.A.) Inc.	N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
US4731360A (en) *	1985-08-16	1988-03-15	Merck & Co., Inc.	Acylcarnitines as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal compartments
DE3635864A1 (de) *	1986-06-26	1988-05-05	Gerhard Gergely	Verfahren zum herstellen eines brausegranulates, danach hergestelltes brausegranulat sowie dessen verwendung
US5078997A (en) *	1988-07-13	1992-01-07	Cetus Corporation	Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers
IL99699A (en)	1990-10-10	2002-04-21	Autoimmune Inc	Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes
US5321009A (en) *	1991-04-03	1994-06-14	American Home Products Corporation	Method of treating diabetes
US5420108A (en) *	1992-09-14	1995-05-30	Shohet; Isaac H.	Method of controlling diabetes mellitus
MA26553A1 (fr) *	1997-10-17	2004-12-20	Centaur Pharmaceuticals Inc	Alpha-aryl-n-alkylnitrones et compositions pharmaceutiques contenant ceux-la
IT1306178B1 (it) *	1999-07-27	2001-05-30	Sigma Tau Ind Farmaceuti	Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da
WO2002065993A2 (en) *	2001-01-08	2002-08-29	Centaur Pharmaceuticals, Inc.	Use of aryl nitrone compounds in methods for treating neuropathic pain
US20050232911A1 (en) *	2004-04-19	2005-10-20	Schreiber Brian D	Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
ITRM20040327A1 (it) *	2004-07-01	2004-10-01	Sigma Tau Ind Farmaceuti	Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici.
RU2324479C2 (ru) *	2006-07-11	2008-05-20	Денис Владимирович Сидько	Способ комплексной инфузионной терапии у больных с гипергликемической кетоацидотической диабетической комой
JP2010527952A (ja) *	2007-05-24	2010-08-19	シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ	Ｐｐａｒ−ガンマアゴニストの使用に起因する有害作用の防止に有用な組成物
CN107121540B (zh) *	2016-02-24	2020-06-12	中国科学院上海营养与健康研究所	酰基肉碱谱或其检测试剂在2型糖尿病发病风险预测中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3624887A (en) *	1970-03-02	1971-12-07	Bunker Ramo	Pin and socket removal tool
US3810994A (en) *	1972-06-01	1974-05-14	Ethyl Corp	Method and composition for treating obesity
JPS5058213A ( ) *	1973-09-26	1975-05-21
FR2414914A1 (fr) *	1978-01-18	1979-08-17	Sigma Tau Ind Farmaceuti	Utilisations therapeutiques nouvelles de l'acetyl-1-carnitine et d'autres derives acyles de la 1-carnitine

1980
- 1980-05-15 IT IT48692/80A patent/IT1133010B/it active
1981
- 1981-05-07 IE IE1011/81A patent/IE51224B1/en not_active IP Right Cessation
- 1981-05-12 GB GB8114456A patent/GB2075838B/en not_active Expired
- 1981-05-12 AU AU70486/81A patent/AU540859B2/en not_active Expired
- 1981-05-12 IL IL62847A patent/IL62847A/xx not_active IP Right Cessation
- 1981-05-13 CA CA000377523A patent/CA1173749A/en not_active Expired
- 1981-05-13 SE SE8103003A patent/SE8103003L/ unknown
- 1981-05-14 NL NL8102384A patent/NL8102384A/nl not_active Application Discontinuation
- 1981-05-14 CH CH3155/81A patent/CH654208A5/it not_active IP Right Cessation
- 1981-05-14 BE BE0/204781A patent/BE888797A/fr not_active IP Right Cessation
- 1981-05-15 DE DE19813119460 patent/DE3119460A1/de not_active Ceased
- 1981-05-15 US US06/264,044 patent/US4362719A/en not_active Expired - Lifetime
- 1981-05-15 JP JP7407781A patent/JPS579721A/ja active Pending
- 1981-05-15 FR FR8109780A patent/FR2482588B1/fr not_active Expired

Also Published As

Publication number	Publication date
CA1173749A (en)	1984-09-04
IT8048692A0 (it)	1980-05-15
GB2075838A (en)	1981-11-25
AU7048681A (en)	1981-11-26
NL8102384A (nl)	1981-12-01
JPS579721A (en)	1982-01-19
FR2482588B1 (fr)	1986-03-07
IE51224B1 (en)	1986-11-12
BE888797A (fr)	1981-08-28
IE811011L (en)	1981-11-15
IL62847A0 (en)	1981-07-31
IT1133010B (it)	1986-07-09
FR2482588A1 (fr)	1981-11-20
CH654208A5 (it)	1986-02-14
GB2075838B (en)	1984-05-10
US4362719A (en)	1982-12-07
DE3119460A1 (de)	1982-03-04
IL62847A (en)	1985-01-31
AU540859B2 (en)	1984-12-06

Publication	Publication Date	Title
NO931267L (no)	1993-05-05	Fremgangsmaate for behandling eller forebyggelse av type 1diabetes ved oral administrering av insulin
IE811011L (en)	1981-11-15	Insulin-carnitine compositions
Crosby	1984	The rationale for treating iron deficiency anemia
DE3468323D1 (en)	1988-02-11	Pharmaceutical formulation for the treatment of diabetes mellitus
AU599792B2 (en)	1990-07-26	Anti-parkinsonian indolone derivatives
GR3003405T3 (en)	1993-02-17	Use of acetyl l-carnitine for the preparation of a medicament for the therapeutical treatment of peripheral neuropathies
DE58901401D1 (de)	1992-06-17	Pharmazeutische zubereitung zur behandlung des diabetes mellitus.
IE790951L (en)	1979-11-15	Carnitine solution
DE68911891D1 (de)	1994-02-10	Verwendung von Acetyl-L-carnitin zur Behandlung von Katarakt, sowie pharmazeutische Zusammensetzungen für eine derartige Behandlung.
KR880013555A (ko)	1988-12-21	당뇨병의 치료방법
DE3162614D1 (en)	1984-04-19	Dibenzoxazepine derivative, process for preparing the same and pharmaceutical composition comprising the same
SE8500996D0 (sv)	1985-03-01	Method of treatment
JPS57126420A (en)	1982-08-06	Drug for digestive organ
KR890006227A (ko)	1989-06-12	페놀-함유 진해성 액체 조성물
ATE79749T1 (de)	1992-09-15	Verwendung von einigen alkanoyl-l-carnitinen zur herstellung eines arzneimittels zur therapeutischen behandlung von ideopathischem oder induziertem parkinsonismus.
RU96115219A (ru)	1998-10-27	Способ лечения больных сахарным диабетом
KR920702225A (ko)	1992-09-03	약학 조성물
US3929995A (en)	1975-12-30	Method for treating diabetic ketoacidosis
KR900700102A (ko)	1990-08-11	심장질환 치료에 쓰이는 프로파페논과 퀴니딘의 지속성 조성물
SU606242A1 (ru)	1978-12-30	Антилепрозное средство "димоцифон"
JPS5569510A (en)	1980-05-26	Carcinostatic agent
Friedman et al.	1951	Renal excretion of digitoxin as an indicator of (1) adequate and (2) excessive digitalization
KR870009722A (ko)	1987-11-30	지방 및 탄수화물 대사조절에서의 엔프로스틸형 프로스타글란딘의 용도
ATE73326T1 (de)	1992-03-15	Verwendung von l-carnitin zur herstellung eines arzneimittels zur behandlung von toxischen effekten, induziert durch die inhalation von halotan und anderen halogen enthaltenden allgemeinen anaesthetika.
ZA918023B (en)	1992-07-29	Novel p-oxybenzoic acid derivatives,process for the preparation thereof and use thereof as drug