SE8206143L - PROCEDURE FOR PREPARING 4- (3-METHYL-2-BUTENYL) -1,2-DIPHENYL-3,5-DIOXOPYRAZOLIDINE - Google Patents

PROCEDURE FOR PREPARING 4- (3-METHYL-2-BUTENYL) -1,2-DIPHENYL-3,5-DIOXOPYRAZOLIDINE

Info

Publication number
SE8206143L
SE8206143L SE8206143A SE8206143A SE8206143L SE 8206143 L SE8206143 L SE 8206143L SE 8206143 A SE8206143 A SE 8206143A SE 8206143 A SE8206143 A SE 8206143A SE 8206143 L SE8206143 L SE 8206143L
Authority
SE
Sweden
Prior art keywords
dioxopyrazolidine
diphenyl
methyl
butenyl
preparing
Prior art date
Application number
SE8206143A
Other languages
Swedish (sv)
Other versions
SE8206143D0 (en
Inventor
A Donetti
M G Quintero
Original Assignee
Angeli Inst Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeli Inst Spa filed Critical Angeli Inst Spa
Publication of SE8206143D0 publication Critical patent/SE8206143D0/en
Publication of SE8206143L publication Critical patent/SE8206143L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/28—Two oxygen or sulfur atoms
    • C07D231/30—Two oxygen or sulfur atoms attached in positions 3 and 5
    • C07D231/32—Oxygen atoms
    • C07D231/34—Oxygen atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

4-(3-Methyl-2-butenyl)-1,2- diphenyl-3,5-dioxopyrazolidine (Feprazone) is prepared by reacting 3- methyl-2-butenyl acetate with an alkali metal salt of 1,2-diphenyl-3,5- dioxopyrazolidine in the presence of a catalyst, preferably a palladium complex, and a ligand.
SE8206143A 1981-10-29 1982-10-28 PROCEDURE FOR PREPARING 4- (3-METHYL-2-BUTENYL) -1,2-DIPHENYL-3,5-DIOXOPYRAZOLIDINE SE8206143L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT24772/81A IT1168184B (en) 1981-10-29 1981-10-29 PROCESS FOR THE PREPARATION OF 4- (3-METHYL-2-BUTANYL) -1,2-DIPHENYL-3,5 DICHETOPYRAZOLIDINE

Publications (2)

Publication Number Publication Date
SE8206143D0 SE8206143D0 (en) 1982-10-28
SE8206143L true SE8206143L (en) 1983-04-30

Family

ID=11214682

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8206143A SE8206143L (en) 1981-10-29 1982-10-28 PROCEDURE FOR PREPARING 4- (3-METHYL-2-BUTENYL) -1,2-DIPHENYL-3,5-DIOXOPYRAZOLIDINE

Country Status (19)

Country Link
JP (1) JPS5888365A (en)
KR (1) KR840001955A (en)
AR (1) AR231832A1 (en)
AT (1) AT379151B (en)
CA (1) CA1179354A (en)
CH (1) CH651555A5 (en)
DK (1) DK477882A (en)
ES (1) ES8308855A1 (en)
FI (1) FI823545L (en)
FR (1) FR2515646B1 (en)
GB (1) GB2108125B (en)
GR (1) GR77724B (en)
IT (1) IT1168184B (en)
NL (1) NL8204170A (en)
NO (1) NO823596L (en)
PH (1) PH19644A (en)
PT (1) PT75755B (en)
SE (1) SE8206143L (en)
YU (1) YU240282A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107778247A (en) * 2016-08-30 2018-03-09 天津太平洋制药有限公司 A kind of preparation method of feprazone and its intermediate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1301857A (en) * 1969-06-27 1973-01-04

Also Published As

Publication number Publication date
NO823596L (en) 1983-05-02
GB2108125A (en) 1983-05-11
CA1179354A (en) 1984-12-11
PH19644A (en) 1986-06-04
FI823545A7 (en) 1983-04-30
GR77724B (en) 1984-09-25
FR2515646B1 (en) 1986-02-14
GB2108125B (en) 1985-03-20
AR231832A1 (en) 1985-03-29
ES516902A0 (en) 1983-10-01
PT75755A (en) 1982-11-01
NL8204170A (en) 1983-05-16
ATA370382A (en) 1985-04-15
IT1168184B (en) 1987-05-20
IT8124772A1 (en) 1983-04-29
PT75755B (en) 1985-11-20
FI823545L (en) 1983-04-30
FR2515646A1 (en) 1983-05-06
CH651555A5 (en) 1985-09-30
SE8206143D0 (en) 1982-10-28
JPS5888365A (en) 1983-05-26
DK477882A (en) 1983-04-30
FI823545A0 (en) 1982-10-18
YU240282A (en) 1985-03-20
AT379151B (en) 1985-11-25
ES8308855A1 (en) 1983-10-01
KR840001955A (en) 1984-06-07
IT8124772A0 (en) 1981-10-29

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