SE8301997L - Framstellning av 6,11-dihydro-11-oxodibens(b,e)-oxepin-2-ettiksyra - Google Patents
Framstellning av 6,11-dihydro-11-oxodibens(b,e)-oxepin-2-ettiksyraInfo
- Publication number
- SE8301997L SE8301997L SE8301997A SE8301997A SE8301997L SE 8301997 L SE8301997 L SE 8301997L SE 8301997 A SE8301997 A SE 8301997A SE 8301997 A SE8301997 A SE 8301997A SE 8301997 L SE8301997 L SE 8301997L
- Authority
- SE
- Sweden
- Prior art keywords
- oxepin
- dihydro
- preparation
- oxodibence
- acid
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- QFGMXJOBTNZHEL-UHFFFAOYSA-N isoxepac Chemical compound O1CC2=CC=CC=C2C(=O)C2=CC(CC(=O)O)=CC=C21 QFGMXJOBTNZHEL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/843,482 US4118401A (en) | 1977-10-19 | 1977-10-19 | Preparation of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid and precursors therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8301997D0 SE8301997D0 (sv) | 1983-04-11 |
| SE8301997L true SE8301997L (sv) | 1983-04-11 |
Family
ID=25290114
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7810895A SE7810895L (sv) | 1977-10-19 | 1978-10-19 | Framstellning av 6,11-dihydro-11-oxodibens(b,e)-oxepin-2-ettiksyra och mellanprodukter herfor |
| SE8301997A SE8301997L (sv) | 1977-10-19 | 1983-04-11 | Framstellning av 6,11-dihydro-11-oxodibens(b,e)-oxepin-2-ettiksyra |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7810895A SE7810895L (sv) | 1977-10-19 | 1978-10-19 | Framstellning av 6,11-dihydro-11-oxodibens(b,e)-oxepin-2-ettiksyra och mellanprodukter herfor |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US4118401A (sv) |
| JP (1) | JPS5461189A (sv) |
| AR (2) | AR223329A1 (sv) |
| AT (1) | AT369737B (sv) |
| CA (1) | CA1110636A (sv) |
| ES (2) | ES474162A1 (sv) |
| HU (1) | HU180245B (sv) |
| NL (1) | NL7810456A (sv) |
| SE (2) | SE7810895L (sv) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4118401A (en) * | 1977-10-19 | 1978-10-03 | American Hoechst Corporation | Preparation of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid and precursors therefor |
| US4515946A (en) * | 1981-12-23 | 1985-05-07 | Hoechst-Roussel Pharmaceuticals Inc. | 6,11-Dihydro-11-oxo-dibenz-[b,e]oxepin derivatives |
| US4576960A (en) * | 1981-12-23 | 1986-03-18 | Hoechst Roussel Pharmaceuticals Incorporated | 6,11-Dihydro-11-oxo-dibenz[b,e]oxepin derivatives |
| US7687646B2 (en) * | 2006-03-28 | 2010-03-30 | Azad Pharmaceutical Ingredients, Ag | Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof |
| EP3007689B1 (en) | 2013-01-10 | 2018-03-07 | Pulmokine, Inc. | Non-selective kinase inhibitors |
| US9925184B2 (en) | 2013-10-11 | 2018-03-27 | Pulmokine, Inc. | Spray-dry formulations |
| CN106518833A (zh) * | 2015-09-15 | 2017-03-22 | 江苏吉贝尔药业股份有限公司 | 一种新的6,11-二氢-11-氧代二苯并[b,e]噁庚因-2-乙酸制备方法 |
| RU2763525C2 (ru) | 2016-10-27 | 2021-12-30 | Пульмокин, Инк. | Комбинированная терапия для лечения легочной гипертензии |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1409411A (fr) * | 1964-07-16 | 1965-08-27 | Imprimerie Darboy | Perfectionnements apportés aux moyens pour l'élaboration d'emballages transparents étanches et aux emballages correspondants |
| FR1409441A (fr) * | 1964-07-17 | 1965-08-27 | France Ministre Des Armees | Perfectionnements au procédé de préparation d'acides para-alkoxy-phénylalkylène-carboxyliques |
| YU204274A (en) | 1973-07-24 | 1982-06-30 | Hoechst Ag | Process for preparing new dibenzoxepin derivatives |
| DE2600768C2 (de) * | 1975-02-04 | 1983-10-27 | Hoechst Ag, 6230 Frankfurt | Verfahren zur Herstellung von 6,11-Dihydro-11-oxodibenz[b,e]-oxepin-alkansäuren |
| US4118401A (en) * | 1977-10-19 | 1978-10-03 | American Hoechst Corporation | Preparation of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid and precursors therefor |
-
1977
- 1977-10-19 US US05/843,482 patent/US4118401A/en not_active Expired - Lifetime
- 1977-12-09 JP JP14726577A patent/JPS5461189A/ja active Pending
-
1978
- 1978-09-05 US US05/939,263 patent/US4160781A/en not_active Expired - Lifetime
- 1978-09-05 US US05/939,267 patent/US4153791A/en not_active Expired - Lifetime
- 1978-09-05 US US05/939,177 patent/US4153790A/en not_active Expired - Lifetime
- 1978-10-10 HU HU78HO2108A patent/HU180245B/hu unknown
- 1978-10-13 ES ES474162A patent/ES474162A1/es not_active Expired
- 1978-10-17 AR AR274108A patent/AR223329A1/es active
- 1978-10-18 CA CA313,659A patent/CA1110636A/en not_active Expired
- 1978-10-18 AT AT0747878A patent/AT369737B/de not_active IP Right Cessation
- 1978-10-18 NL NL7810456A patent/NL7810456A/xx not_active Application Discontinuation
- 1978-10-19 SE SE7810895A patent/SE7810895L/sv unknown
- 1978-11-10 ES ES474975A patent/ES474975A1/es not_active Expired
-
1980
- 1980-08-06 AR AR282065A patent/AR224905A1/es active
-
1983
- 1983-04-11 SE SE8301997A patent/SE8301997L/sv not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES474162A1 (es) | 1979-09-01 |
| US4118401A (en) | 1978-10-03 |
| SE8301997D0 (sv) | 1983-04-11 |
| ES474975A1 (es) | 1980-02-16 |
| US4153790A (en) | 1979-05-08 |
| CA1110636A (en) | 1981-10-13 |
| AT369737B (de) | 1983-01-25 |
| AR223329A1 (es) | 1981-08-14 |
| ATA747878A (de) | 1982-06-15 |
| SE7810895L (sv) | 1979-04-20 |
| US4160781A (en) | 1979-07-10 |
| US4153791A (en) | 1979-05-08 |
| JPS5461189A (en) | 1979-05-17 |
| HU180245B (en) | 1983-02-28 |
| AR224905A1 (es) | 1982-01-29 |
| NL7810456A (nl) | 1979-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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