SE8306475L - cephalosporin antibiotics - Google Patents
cephalosporin antibioticsInfo
- Publication number
- SE8306475L SE8306475L SE8306475A SE8306475A SE8306475L SE 8306475 L SE8306475 L SE 8306475L SE 8306475 A SE8306475 A SE 8306475A SE 8306475 A SE8306475 A SE 8306475A SE 8306475 L SE8306475 L SE 8306475L
- Authority
- SE
- Sweden
- Prior art keywords
- gram
- cephalosporin antibiotics
- toxic
- dioxotriazine
- tetrazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Cephalosporin antibiotics of general formula <IMAGE> (wherein Y represents a carbon- linked 5- or 6-membered unsaturated heterocyclic ring containing at least one nitrogen atom, such as pyridine or tetrazole, which ring may also contain one or more sulphur atoms and/or may be substituted by one or more C1-4 alkyl, oxo, hydroxy or carbamoyl-methyl groups such as dioxotriazine), and non-toxic salts and non-toxic metabolically labile esters thereof and pharmaceutical compositions containing them are described. The compounds exhibit broad spectrum antibiotic activity both in vitro and in vivo, having good activity against both Gram-positive and Gram-negative organisms.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8233521 | 1982-11-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8306475D0 SE8306475D0 (en) | 1983-11-23 |
| SE8306475L true SE8306475L (en) | 1984-05-25 |
Family
ID=10534479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8306475A SE8306475L (en) | 1982-11-24 | 1983-11-23 | cephalosporin antibiotics |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS59106492A (en) |
| KR (1) | KR840006811A (en) |
| AU (1) | AU2161783A (en) |
| BE (1) | BE898293A (en) |
| DE (1) | DE3342317A1 (en) |
| DK (1) | DK535083A (en) |
| FI (1) | FI834297A7 (en) |
| FR (1) | FR2536402A1 (en) |
| GB (1) | GB2132193B (en) |
| GR (1) | GR79078B (en) |
| IL (1) | IL70310A0 (en) |
| IT (1) | IT1175800B (en) |
| LU (1) | LU85101A1 (en) |
| NL (1) | NL8304024A (en) |
| NO (1) | NO834304L (en) |
| PT (1) | PT77711B (en) |
| SE (1) | SE8306475L (en) |
| ZA (1) | ZA838733B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0148004A3 (en) * | 1983-12-30 | 1986-04-23 | Glaxo Group Limited | Cephalosporin antibiotics |
| US5202315A (en) * | 1989-05-11 | 1993-04-13 | Lucky, Ltd. | Cephalosporin compounds |
| EP0449515B1 (en) * | 1990-03-24 | 1995-05-24 | Lucky, Ltd. | Novel cephalosporin intermediates and process for preparing the intermediates and their end products |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2714880A1 (en) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | CEPHEMDER DERIVATIVES AND PROCESS FOR THEIR PRODUCTION |
| GB2027691B (en) * | 1978-05-26 | 1983-03-02 | Glaxo Group Ltd | Cephalosporin antibiotics |
-
1983
- 1983-11-22 JP JP58218805A patent/JPS59106492A/en active Pending
- 1983-11-23 NL NL8304024A patent/NL8304024A/en not_active Application Discontinuation
- 1983-11-23 PT PT77711A patent/PT77711B/en unknown
- 1983-11-23 DE DE19833342317 patent/DE3342317A1/en not_active Withdrawn
- 1983-11-23 FR FR8318658A patent/FR2536402A1/en not_active Withdrawn
- 1983-11-23 IL IL70310A patent/IL70310A0/en unknown
- 1983-11-23 NO NO834304A patent/NO834304L/en unknown
- 1983-11-23 FI FI834297A patent/FI834297A7/en not_active Application Discontinuation
- 1983-11-23 LU LU85101A patent/LU85101A1/en unknown
- 1983-11-23 GR GR73051A patent/GR79078B/el unknown
- 1983-11-23 KR KR1019830005536A patent/KR840006811A/en not_active Withdrawn
- 1983-11-23 GB GB08331292A patent/GB2132193B/en not_active Expired
- 1983-11-23 SE SE8306475A patent/SE8306475L/en not_active Application Discontinuation
- 1983-11-23 AU AU21617/83A patent/AU2161783A/en not_active Abandoned
- 1983-11-23 ZA ZA838733A patent/ZA838733B/en unknown
- 1983-11-23 IT IT49380/83A patent/IT1175800B/en active
- 1983-11-23 BE BE0/211922A patent/BE898293A/en not_active IP Right Cessation
- 1983-11-23 DK DK535083A patent/DK535083A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2536402A1 (en) | 1984-05-25 |
| IT8349380A1 (en) | 1985-05-23 |
| GR79078B (en) | 1984-10-02 |
| GB8331292D0 (en) | 1983-12-29 |
| ZA838733B (en) | 1985-01-30 |
| NL8304024A (en) | 1984-06-18 |
| JPS59106492A (en) | 1984-06-20 |
| IL70310A0 (en) | 1984-02-29 |
| PT77711B (en) | 1986-03-27 |
| AU2161783A (en) | 1984-05-31 |
| DK535083D0 (en) | 1983-11-23 |
| GB2132193B (en) | 1985-12-18 |
| FI834297A0 (en) | 1983-11-23 |
| GB2132193A (en) | 1984-07-04 |
| NO834304L (en) | 1984-05-25 |
| DE3342317A1 (en) | 1984-05-24 |
| PT77711A (en) | 1983-12-01 |
| BE898293A (en) | 1984-05-23 |
| IT1175800B (en) | 1987-07-15 |
| IT8349380A0 (en) | 1983-11-23 |
| DK535083A (en) | 1984-05-25 |
| SE8306475D0 (en) | 1983-11-23 |
| KR840006811A (en) | 1984-12-03 |
| FI834297A7 (en) | 1984-05-25 |
| LU85101A1 (en) | 1984-06-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 8306475-8 Effective date: 19851018 |