SE8405488L - Naftyl- eller tetrahydronaftylsubstituerad naftoesyra och derivat derav - Google Patents
Naftyl- eller tetrahydronaftylsubstituerad naftoesyra och derivat deravInfo
- Publication number
- SE8405488L SE8405488L SE8405488A SE8405488A SE8405488L SE 8405488 L SE8405488 L SE 8405488L SE 8405488 A SE8405488 A SE 8405488A SE 8405488 A SE8405488 A SE 8405488A SE 8405488 L SE8405488 L SE 8405488L
- Authority
- SE
- Sweden
- Prior art keywords
- hydrogen
- naphthyl
- derivatives
- naphthoic acid
- image
- Prior art date
Links
- 150000005209 naphthoic acids Chemical class 0.000 title 1
- 125000001624 naphthyl group Chemical group 0.000 title 1
- 125000001712 tetrahydronaphthyl group Chemical group C1(CCCC2=CC=CC=C12)* 0.000 title 1
- 239000001257 hydrogen Chemical group 0.000 abstract 4
- 229910052739 hydrogen Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229940124443 chemopreventive agent Drugs 0.000 abstract 1
- 239000012627 chemopreventive agent Substances 0.000 abstract 1
- 210000002919 epithelial cell Anatomy 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- UCFFGYASXIPWPD-UHFFFAOYSA-N methyl hypochlorite Chemical group COCl UCFFGYASXIPWPD-UHFFFAOYSA-N 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
- C07C17/12—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the ring of aromatic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
- C07C17/269—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions of only halogenated hydrocarbons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/33—Polycyclic acids
- C07C63/337—Polycyclic acids with carboxyl groups bound to condensed ring systems
- C07C63/42—Polycyclic acids with carboxyl groups bound to condensed ring systems containing three or more condensed rings
- C07C63/44—Polycyclic acids with carboxyl groups bound to condensed ring systems containing three or more condensed rings containing one carboxyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/33—Polycyclic acids
- C07C63/49—Polycyclic acids containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/68—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings containing halogen
- C07C63/72—Polycyclic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
- C07C65/26—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic containing rings other than six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/471,744 US4454341A (en) | 1983-03-03 | 1983-03-03 | Naphthyl or tetrahydronaphthyl-substituted naphthoic acid and derivatives |
| PCT/US1984/000067 WO1984003505A1 (en) | 1983-03-03 | 1984-01-16 | Naphthyl or tetrahydronaphthyl-substituted naphthoic acid and de rivates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8405488D0 SE8405488D0 (sv) | 1984-11-01 |
| SE8405488L true SE8405488L (sv) | 1984-11-01 |
Family
ID=23872826
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8405488A SE8405488L (sv) | 1983-03-03 | 1984-11-01 | Naftyl- eller tetrahydronaftylsubstituerad naftoesyra och derivat derav |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4454341A (da) |
| EP (1) | EP0137010A4 (da) |
| JP (1) | JPS60500815A (da) |
| DE (1) | DE3490104T1 (da) |
| DK (1) | DK524784D0 (da) |
| GB (1) | GB2143824B (da) |
| NO (1) | NO844373L (da) |
| SE (1) | SE8405488L (da) |
| WO (1) | WO1984003505A1 (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2555571B1 (fr) * | 1983-11-28 | 1986-11-28 | Interna Rech Dermatolo Centre | Derives du naphtalene, leur procede de preparation et leur application dans le domaine therapeutique |
| FR2573755B1 (fr) * | 1984-11-27 | 1988-04-22 | Cird | Derives polysubstitues du naphtalene, leur procede de preparation et leur application dans les domaines pharmaceutique et cosmetique |
| LU85726A1 (fr) * | 1985-01-10 | 1986-08-04 | Cird | Nouveaux derives naphtaleniques du benzonorbornene,leur procede de preparation et compositions medicamenteuse et cosmetique les contenant |
| US4593125A (en) * | 1985-03-13 | 1986-06-03 | Celanese Corporation | Acylation of naphthalenes |
| LU85849A1 (fr) * | 1985-04-11 | 1986-11-05 | Cird | Derives benzonaphtaleniques,leur procede de preparation et leur application dans les domaines pharmaceutiques et cosmetiques |
| FR2601359B1 (fr) * | 1986-07-09 | 1988-10-28 | Cird | Nouveaux derives bicycliques naphtaleniques, leur procede de preparation et leur utilisation en medecine humaine et veterinaire et en cosmetique. |
| IL80270A0 (en) * | 1985-10-11 | 1987-01-30 | Cird | Naphthalene derivatives,their preparation and pharmaceutical compositions containing them |
| IT1221916B (it) * | 1987-03-13 | 1990-08-23 | Blaschim Spa | Metodo migliorato epr acilare un derivato del naftalene |
| DE3816120A1 (de) * | 1988-05-11 | 1989-11-23 | Bayer Ag | Verfahren zur herstellung von unsymmetrischen biarylverbindungen |
| US5475022A (en) * | 1993-10-18 | 1995-12-12 | Allergan, Inc. | Phenyl or heteroaryl and tetrahydronaphthyl substituted diene compounds having retinoid like biological activity |
| CA2138000A1 (en) * | 1994-01-03 | 1995-07-04 | John E. Starrett, Jr. | Retinoid-like compounds |
| US5648385A (en) * | 1994-01-03 | 1997-07-15 | Bristol-Myers Squibb Co. | Retinoid-like compounds |
| US5559248A (en) * | 1995-04-05 | 1996-09-24 | Bristol-Myers Squibb Co. | Retinoid-like heterocycles |
| US5747542A (en) * | 1996-06-21 | 1998-05-05 | Allergan | Oxo-substituted tetrahydronaphthalene derivatives having retinold and/or retinoid antagonist-like biological activity |
| WO2012056544A1 (ja) * | 2010-10-28 | 2012-05-03 | エア・ウォーター株式会社 | 6-ブロモ-2-ナフタレンカルボン酸精製品の製造方法 |
| WO2014069674A1 (ja) * | 2012-11-01 | 2014-05-08 | スガイ化学工業株式会社 | 6-ブロモ-2-ナフトエ酸の製造方法 |
| WO2015188015A1 (en) | 2014-06-04 | 2015-12-10 | Haro Pharmaceutical Inc. | 18-20 member bi-polycyclic compounds |
| WO2016105547A1 (en) | 2014-12-24 | 2016-06-30 | Concert Pharmaceuticals, Inc. | Deuterated dasabuvir |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3896157A (en) * | 1967-01-13 | 1975-07-22 | Syntex Corp | Dihydo 2-naphthylacetic acid derivatives |
| US3821253A (en) * | 1969-04-09 | 1974-06-28 | Syntex Corp | Naphthyl acetaldehyde derivatives;methods of use thereof;and processes for the preparation thereof |
| US4326055A (en) * | 1977-12-22 | 1982-04-20 | Hoffmann-La Roche Inc. | Stilbene derivatives |
| FR2416214A1 (fr) * | 1978-02-02 | 1979-08-31 | Inst Rech Scient Irs | Derives d'acide naphtyl-1 acetique, leur procede de preparation et leur application therapeutique |
-
1983
- 1983-03-03 US US06/471,744 patent/US4454341A/en not_active Expired - Fee Related
-
1984
- 1984-01-16 EP EP19840900792 patent/EP0137010A4/en not_active Withdrawn
- 1984-01-16 DE DE19843490104 patent/DE3490104T1/de not_active Withdrawn
- 1984-01-16 WO PCT/US1984/000067 patent/WO1984003505A1/en not_active Ceased
- 1984-01-16 JP JP59500830A patent/JPS60500815A/ja active Pending
- 1984-01-16 GB GB08424775A patent/GB2143824B/en not_active Expired
- 1984-11-01 SE SE8405488A patent/SE8405488L/xx not_active Application Discontinuation
- 1984-11-02 DK DK524784A patent/DK524784D0/da not_active Application Discontinuation
- 1984-11-02 NO NO844373A patent/NO844373L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE8405488D0 (sv) | 1984-11-01 |
| GB2143824B (en) | 1986-09-10 |
| DK524784A (da) | 1984-11-02 |
| DE3490104T1 (de) | 1985-04-04 |
| NO844373L (no) | 1984-11-02 |
| WO1984003505A1 (en) | 1984-09-13 |
| EP0137010A4 (en) | 1985-08-12 |
| GB8424775D0 (en) | 1984-11-07 |
| JPS60500815A (ja) | 1985-05-30 |
| US4454341A (en) | 1984-06-12 |
| DK524784D0 (da) | 1984-11-02 |
| GB2143824A (en) | 1985-02-20 |
| EP0137010A1 (en) | 1985-04-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 8405488-1 Effective date: 19861212 |