SE8601852L - CYCLOPENTYLETRES AND THEIR PREPARATION AND PHARMACEUTICAL PREPARATION - Google Patents

CYCLOPENTYLETRES AND THEIR PREPARATION AND PHARMACEUTICAL PREPARATION

Info

Publication number
SE8601852L
SE8601852L SE8601852A SE8601852A SE8601852L SE 8601852 L SE8601852 L SE 8601852L SE 8601852 A SE8601852 A SE 8601852A SE 8601852 A SE8601852 A SE 8601852A SE 8601852 L SE8601852 L SE 8601852L
Authority
SE
Sweden
Prior art keywords
preparation
cyclopentyletres
pharmaceutical
phenyl
substituted
Prior art date
Application number
SE8601852A
Other languages
Swedish (sv)
Other versions
SE460193B (en
SE8601852D0 (en
Inventor
E W Collington
H Finch
D B Judd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SE8601852D0 publication Critical patent/SE8601852D0/en
Publication of SE8601852L publication Critical patent/SE8601852L/en
Publication of SE460193B publication Critical patent/SE460193B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compounds are described of formula (I> <IMAGE> in which n is 1 or 2; m is 2-5 and x is -CH=CH- or -CH2-CH2-; or m is 1-4 and x is -CH=C=CH-; R<1> is phenyl, substituted phenyl or naphthyl; Y substituted or unsubstituted 3-phenoxy-2-hydroxypropyl. These compounds inhibit gastric acid secretion and provide gastrointestinal cytoprotection, and may be formulated for use in the treatment of ulcers.
SE8601852A 1985-04-23 1986-04-22 13-OXAPROSTAGLANDINES OF PGE TYPE, SET TO MANUFACTURING THESE AND A PHARMACEUTICAL COMPOSITION SE460193B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858510277A GB8510277D0 (en) 1985-04-23 1985-04-23 Carbocyclic compounds

Publications (3)

Publication Number Publication Date
SE8601852D0 SE8601852D0 (en) 1986-04-22
SE8601852L true SE8601852L (en) 1986-10-24
SE460193B SE460193B (en) 1989-09-18

Family

ID=10578043

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8601852A SE460193B (en) 1985-04-23 1986-04-22 13-OXAPROSTAGLANDINES OF PGE TYPE, SET TO MANUFACTURING THESE AND A PHARMACEUTICAL COMPOSITION

Country Status (29)

Country Link
JP (1) JPS61249951A (en)
KR (1) KR860008132A (en)
CN (1) CN1011783B (en)
AT (1) AT395421B (en)
AU (1) AU593797B2 (en)
BE (1) BE904656A (en)
CA (1) CA1275094A (en)
CH (1) CH667265A5 (en)
DE (1) DE3613573A1 (en)
DK (1) DK183986A (en)
ES (3) ES8802137A1 (en)
FI (1) FI85368C (en)
FR (1) FR2580632B1 (en)
GB (2) GB8510277D0 (en)
GR (1) GR861060B (en)
HK (1) HK51691A (en)
HU (1) HU199411B (en)
IL (1) IL78552A (en)
IT (1) IT1190277B (en)
LU (1) LU86404A1 (en)
MY (1) MY100829A (en)
NL (1) NL8601025A (en)
NO (1) NO165069C (en)
NZ (1) NZ215910A (en)
PH (1) PH23597A (en)
PT (1) PT82440B (en)
SE (1) SE460193B (en)
SG (1) SG92990G (en)
ZA (1) ZA863006B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8625326D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Medicaments
GB8625325D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
GB8625321D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
GB8625322D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
US4847369A (en) * 1986-10-22 1989-07-11 Glaxo Group Limited Cyclopentyl ethers and their preparation and pharmaceutical formulation
US5227505A (en) * 1987-06-16 1993-07-13 Nissan Chemical Industries, Ltd. Substituted cyclic ketones, substituted cyclic enones, and process for producing the same
US5254708A (en) * 1987-06-16 1993-10-19 Nissan Chemical Industries, Ltd. Substituted cyclic ketones, substituted cyclic enones, and process for producing the same
JP2696933B2 (en) * 1987-06-16 1998-01-14 日産化学工業株式会社 Substituted cyclic ketones and substituted cyclic enones and methods for their preparation
US5231208A (en) * 1987-06-16 1993-07-27 Nissan Chemical Industries, Ltd. Substituted cyclic ketones, substituted cyclic enones, and process for producing the same
GB8822141D0 (en) * 1988-09-21 1988-10-26 Glaxo Group Ltd Chemical compounds
US6232344B1 (en) 1997-12-22 2001-05-15 Alcon Laboratories, Inc. 13-Oxa prostaglandins for the treatment of glaucoma and ocular hypertension
EP2422814A1 (en) 2003-07-25 2012-02-29 Ono Pharmaceutical Co., Ltd. Remedy for cartilage-related diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2082176B (en) * 1980-08-12 1984-07-11 Sanofi Sa Heteroprostaglandin derivatives and processes for preparing them
NZ197729A (en) * 1980-08-12 1985-03-20 Sanofi Sa 13-oxaprostanoic acid derivatives and pharmaceutical compositions
GB8410396D0 (en) * 1984-04-24 1984-05-31 Glaxo Group Ltd Carbocyclic compounds

Also Published As

Publication number Publication date
CA1275094A (en) 1990-10-09
ES9000022A1 (en) 1990-02-16
ZA863006B (en) 1986-12-30
PT82440B (en) 1988-03-03
NL8601025A (en) 1986-11-17
IT8647919A0 (en) 1986-04-22
IL78552A0 (en) 1986-08-31
HU199411B (en) 1990-02-28
ES8900044A1 (en) 1988-11-16
GB8510277D0 (en) 1985-05-30
DK183986A (en) 1986-10-24
AT395421B (en) 1992-12-28
HK51691A (en) 1991-07-12
AU593797B2 (en) 1990-02-22
ES8802137A1 (en) 1988-04-01
NO861584L (en) 1986-10-24
CN86102778A (en) 1986-10-22
FI85368B (en) 1991-12-31
GB8609821D0 (en) 1986-05-29
FI861687A0 (en) 1986-04-22
SE460193B (en) 1989-09-18
ES557828A0 (en) 1990-02-16
KR860008132A (en) 1986-11-12
FI85368C (en) 1992-04-10
ATA106986A (en) 1992-05-15
ES557659A0 (en) 1988-11-16
GR861060B (en) 1986-08-25
FR2580632B1 (en) 1989-09-15
FR2580632A1 (en) 1986-10-24
NZ215910A (en) 1989-08-29
CH667265A5 (en) 1988-09-30
LU86404A1 (en) 1986-11-05
DE3613573A1 (en) 1986-10-30
DK183986D0 (en) 1986-04-22
IL78552A (en) 1989-12-15
IT1190277B (en) 1988-02-16
NO165069B (en) 1990-09-10
CN1011783B (en) 1991-02-27
SE8601852D0 (en) 1986-04-22
GB2174702A (en) 1986-11-12
JPS61249951A (en) 1986-11-07
NO165069C (en) 1990-12-19
SG92990G (en) 1991-01-18
PT82440A (en) 1986-05-01
ES554238A0 (en) 1988-04-01
MY100829A (en) 1991-03-15
BE904656A (en) 1986-10-22
FI861687L (en) 1986-10-24
PH23597A (en) 1989-09-11
GB2174702B (en) 1988-06-15
HUT45010A (en) 1988-05-30
AU5646186A (en) 1986-10-30

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