SE8603797L - Forfarande for framstellning av n-sulfamyl-3-(2-guanidino-tiazol-4-yl-metyltio)-propionamidin - Google Patents

Forfarande for framstellning av n-sulfamyl-3-(2-guanidino-tiazol-4-yl-metyltio)-propionamidin

Info

Publication number: SE8603797L
Authority: SE; Sweden
Prior art keywords: sulfamyl; guanidino; metyltio; tiazol; propionamidine
Prior art date: 1985-09-11

Application number

SE8603797A

Other languages

English (en)

Swedish (sv)

Other versions

SE8603797D0 (sv

Inventor

P Bod

K Harsanyi

E Agai

E Bogsch

E Fekecs

F Trischler

G Domany

I Szabadkai

B Hegedus

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-09-11

Filing date

1986-09-10

Publication date

1987-03-12

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10963968&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE8603797(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-09-10 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

1986-09-10 Publication of SE8603797D0 publication Critical patent/SE8603797D0/xx

1987-03-12 Publication of SE8603797L publication Critical patent/SE8603797L/xx

Links

238000000034 method Methods 0.000 title abstract 2
238000005804 alkylation reaction Methods 0.000 abstract 2
AHNNULCXEIGUHA-UHFFFAOYSA-N 2-[4-(sulfanylmethyl)-1,3-thiazol-2-yl]guanidine Chemical compound NC(N)=NC1=NC(CS)=CS1 AHNNULCXEIGUHA-UHFFFAOYSA-N 0.000 abstract 1
FTKAAVQOOXXUGW-UHFFFAOYSA-N [4-[[amino(azaniumylidene)methyl]sulfanylmethyl]-1,3-thiazol-2-yl]-(diaminomethylidene)azanium;dichloride Chemical compound Cl.Cl.NC(=N)SCC1=CSC(N=C(N)N)=N1 FTKAAVQOOXXUGW-UHFFFAOYSA-N 0.000 abstract 1
XUFQPHANEAPEMJ-UHFFFAOYSA-N famotidine Chemical compound NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1 XUFQPHANEAPEMJ-UHFFFAOYSA-N 0.000 abstract 1
229960001596 famotidine Drugs 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
238000011065 in-situ storage Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

SE8603797A 1985-09-11 1986-09-10 Forfarande for framstellning av n-sulfamyl-3-(2-guanidino-tiazol-4-yl-metyltio)-propionamidin SE8603797L (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU853424A HU194845B (en)	1985-09-11	1985-09-11	Process for production of n-sulphamil-3-/2-guanidintiazolil-4-methil-tio/-propion-amidin

Publications (2)

Publication Number	Publication Date
SE8603797D0 SE8603797D0 (sv)	1986-09-10
SE8603797L true SE8603797L (sv)	1987-03-12

Family

ID=10963968

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8603797A SE8603797L (sv)	1985-09-11	1986-09-10	Forfarande for framstellning av n-sulfamyl-3-(2-guanidino-tiazol-4-yl-metyltio)-propionamidin

Country Status (22)

Country	Link
US (1)	US4835281A (da)
JP (1)	JPH0645609B2 (da)
KR (1)	KR910000237B1 (da)
CN (1)	CN1013674B (da)
AR (1)	AR240319A1 (da)
AT (1)	AT386824B (da)
AU (1)	AU587279B2 (da)
BE (1)	BE905409A (da)
CA (1)	CA1263120A (da)
DD (1)	DD249479A5 (da)
DK (1)	DK169920B1 (da)
ES (1)	ES2001677A6 (da)
FI (1)	FI86423C (da)
GB (1)	GB2180237B (da)
GE (1)	GEP19960471B (da)
GR (1)	GR862308B (da)
HU (1)	HU194845B (da)
NL (1)	NL8602225A (da)
NO (1)	NO163010C (da)
PT (1)	PT83348B (da)
SE (1)	SE8603797L (da)
SU (1)	SU1450743A3 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU194845B (en) *	1985-09-11	1988-03-28	Richter Gedeon Vegyeszet	Process for production of n-sulphamil-3-/2-guanidintiazolil-4-methil-tio/-propion-amidin
HU196775B (en) *	1986-08-05	1989-01-30	Richter Gedeon Vegyeszet	Process for production of morfologically unique new modifications of famotidin and medical compositions containing such substances
NO882037L (no) *	1987-06-22	1988-12-23	Marga Para La Investigacion Sa	Famotidin, polymerte former og fremstilling derav.
US5731442A (en) *	1997-03-11	1998-03-24	Albemarle Corporation	Synthesis of thiazole derivatives
US5856500A (en) *	1997-03-11	1999-01-05	Albemarle Corporation	Synthesis of thiazole derivatives
US6552047B2 (en) *	1998-11-17	2003-04-22	Nitromed, Inc.	H2 receptor antagonist compounds in combination with nitric oxide donors, compositions and methods of use
US20110143340A1 (en) *	2007-11-01	2011-06-16	Biocept, Inc.	Non-invasive isolation of fetal nucleic acid

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6056143B2 (ja) *	1979-08-02	1985-12-09	山之内製薬株式会社	アミジン誘導体ならびにその製造法
US4808589A (en) *	1982-02-20	1989-02-28	Smith Kline & French Laboratories Limited	Pyrimidone derivatives
US4496737A (en)	1982-09-27	1985-01-29	Merck & Co., Inc.	Process for preparing sulfamylamidine antisecretory agents
ES526303A0 (es) *	1983-10-07	1985-04-01	Inke Sa	Procedimiento para la obtencion de (-1amino-3-(((2-((diaminometileno) amino)-4-tiazolil)metil)tio)propilideno)sulfamida
ES532239A0 (es) *	1984-05-07	1985-08-01	Inke Sa	Procedimiento para la obtencion de la 1-amino-3-2-diamino-metilen-amino-4-tiazolil-metil-tio-propiliden-sulfamida.
ES536322A0 (es) *	1984-09-27	1985-08-01	Bioiberica	Procedimiento para la obtencion del n-aminosolfenil-3-(((2-guanidin-4-tiazonil)metil)tio) propionamidina
ES8506664A1 (es) *	1984-10-17	1985-08-01	Inke Sa	Procedimiento para la obtencion de la (1-amino-3(((2-((diamino-metilen) amino)-4-tiazolil)metil)tio)propiliden)sulfamida
HU193608B (en) *	1985-09-11	1987-11-30	Richter Gedeon Vegyeszet	Process for production of new dervatives of n-sulphanol-propion-amidine
HU194845B (en) *	1985-09-11	1988-03-28	Richter Gedeon Vegyeszet	Process for production of n-sulphamil-3-/2-guanidintiazolil-4-methil-tio/-propion-amidin
JP3751649B2 (ja) *	1994-12-01	2006-03-01	関西ペイント株式会社	自動車外板塗膜の一時保護方法

1985
- 1985-09-11 HU HU853424A patent/HU194845B/hu unknown
1986
- 1986-08-22 CA CA000516617A patent/CA1263120A/en not_active Expired
- 1986-09-03 NL NL8602225A patent/NL8602225A/nl not_active Application Discontinuation
- 1986-09-08 AR AR305176A patent/AR240319A1/es active
- 1986-09-08 KR KR1019860007508A patent/KR910000237B1/ko not_active Expired
- 1986-09-09 GR GR862308A patent/GR862308B/el unknown
- 1986-09-09 SU SU864028107A patent/SU1450743A3/ru active
- 1986-09-09 DD DD86294264A patent/DD249479A5/de unknown
- 1986-09-10 DK DK434586A patent/DK169920B1/da not_active IP Right Cessation
- 1986-09-10 PT PT83348A patent/PT83348B/pt unknown
- 1986-09-10 NO NO863616A patent/NO163010C/no not_active IP Right Cessation
- 1986-09-10 SE SE8603797A patent/SE8603797L/xx not_active Application Discontinuation
- 1986-09-10 AU AU62569/86A patent/AU587279B2/en not_active Expired
- 1986-09-10 FI FI863657A patent/FI86423C/fi not_active IP Right Cessation
- 1986-09-10 AT AT0243486A patent/AT386824B/de not_active IP Right Cessation
- 1986-09-10 GB GB8621742A patent/GB2180237B/en not_active Expired
- 1986-09-10 BE BE0/217144A patent/BE905409A/fr not_active IP Right Cessation
- 1986-09-10 JP JP61211792A patent/JPH0645609B2/ja not_active Expired - Lifetime
- 1986-09-11 CN CN86105909A patent/CN1013674B/zh not_active Expired
- 1986-09-11 ES ES8601790A patent/ES2001677A6/es not_active Expired
1987
- 1987-07-23 US US07/077,095 patent/US4835281A/en not_active Expired - Lifetime
1993
- 1993-06-14 GE GEAP1993867A patent/GEP19960471B/en unknown

Also Published As

Publication number	Publication date
BE905409A (fr)	1986-12-31
PT83348B (pt)	1988-07-29
CA1263120A (en)	1989-11-21
FI863657A7 (fi)	1987-03-12
ATA243486A (de)	1988-03-15
DK169920B1 (da)	1995-04-03
NL8602225A (nl)	1987-04-01
US4835281A (en)	1989-05-30
AU6256986A (en)	1987-03-12
FI86423C (fi)	1992-08-25
NO863616D0 (no)	1986-09-10
JPS6296481A (ja)	1987-05-02
FI863657A0 (fi)	1986-09-10
AU587279B2 (en)	1989-08-10
FI86423B (fi)	1992-05-15
HU194845B (en)	1988-03-28
ES2001677A6 (es)	1988-06-01
GR862308B (en)	1987-01-02
KR870003078A (ko)	1987-04-15
DK434586D0 (da)	1986-09-10
NO863616L (no)	1987-03-12
GB2180237B (en)	1989-09-06
NO163010C (no)	1990-03-21
GB2180237A (en)	1987-03-25
PT83348A (pt)	1986-10-01
HUT42766A (en)	1987-08-28
GEP19960471B (en)	1996-05-13
GB8621742D0 (en)	1986-10-15
CN1013674B (zh)	1991-08-28
DK434586A (da)	1987-03-12
AR240319A1 (es)	1990-03-30
CN86105909A (zh)	1987-05-13
KR910000237B1 (ko)	1991-01-23
JPH0645609B2 (ja)	1994-06-15
SE8603797D0 (sv)	1986-09-10
NO163010B (no)	1989-12-11
SU1450743A3 (ru)	1989-01-07
AT386824B (de)	1988-10-25
DD249479A5 (de)	1987-09-09

Legal Events

Date

Code

Title

Description

1995-02-28

NAV

Patent application has lapsed

Ref document number: 8603797-5

Effective date: 19910225

Publication	Publication Date	Title
BR8704582A (pt)	1988-04-26	Processo para preparar derivados de piridinacarboxamida
RO83309A (ro)	1984-02-21	Procedeu pentru prepararea (-)-n-metil-3-(2-metil-fenoxi)-3-fenilpropilaminei
PT69775A (fr)	1979-07-01	Procede de preparation de derives de phenylpiperazine
MA19996A1 (fr)	1984-10-01	Procede de preparation de derives disubstitues de la proline
BG42005A3 (en)	1987-09-15	Method for preparing of pyridyl compouds
ES554305A0 (es)	1987-11-16	Procedimiento para la fabricacion de derivados quinolilglicinamidas
SE8603797D0 (sv)	1986-09-10	Process for the preparation of n-sulfamyl-3-(2-guanidino-thiazol-4-yl-methylthio)-propion-amidine
HUT42770A (en)	1987-08-28	Process for preparing novel pyrrolo-benzimidazole derivatives, pyrrolo -benzoxazole derivatives and pyrrolo-benzthiazole derivatives and pharmaceutical compositions comprising the same
RO80298A (ro)	1982-12-06	Procedeu pentru prepararea unor derivati triazolil-alchenici
RO77772A (ro)	1981-11-24	Procedeu pentru prepararea unor derivati de acizi 2,2-dimetilcicloropancarboxilici
DK165282A (da)	1982-10-15	Phenethanolaminderivater,fremgangsmaade til deres fremstillingsamt deres anvendelse
ES2053707T3 (es)	1994-08-01	Procedimiento para la preparacion de amidas de acidos 3,3-diaril-acrilicos.
DK439082A (da)	1983-04-06	4-acylamino-1-aza-adamantan-forbindelser samt fremgangsmaade til fremstilling deraf
ZA878666B (en)	1989-01-25	Derivatives of 2,2-demethyl cyclopropane carboxylic acid containing at 3 a halogen chain,their process and the intermediates of the preparation their application as pesticides and the compositions containing them
RO81506A (ro)	1983-04-29	Procedeu pentru prepararea derivatilor acizilor 1,3,4-tiadiazol-2-carboxilici
IT7925025A0 (it)	1979-08-09	Procedimento per la produzione di diciclopentilen parentesi quadra aperta 2,2'-bis(4-alchil-6-t-butilfenoli)parentesi quadra chiusa.
DK383588D0 (da)	1988-07-08	Fremgangsmaade til fremstilling af substituerede pyridylketoner
DK247279A (da)	1979-12-27	Fremgangsmaade til fremstilling af carbazolderivater
IT1193500B (it)	1988-07-08	Processo per la preparazione di 2,2'-bis/4-(1,1,3,3-tetrametilbutil) fenol/solfuro
DK222087A (da)	1987-04-30	Aeny fremgangsmaade til fremstilling af kemiske for-bindelserae
NO812630L (no)	1982-02-08	Fremgangsmaate for fremstilling av alfa-substituert ureidobenzylpenicillan-syre
BE872634A (fr)	1979-06-08	Procede de production d'halogene par electrolyse.
PT75167B (fr)	1984-02-21	Procede pour la preparation de derives de cystine
FI812773A7 (fi)	1982-03-13	Menetelmä N-/4-/(2,4-diamino-6- pteridinyyli)-metyyli/- metyyliamino/bentsoyyli/glutamiinihapon valmisvalmistamiseksi.
FI831838A7 (fi)	1983-11-26	Menetelmä 2-(Z)- fenyylimetyleenisykloheptaani-johdannaisten valmistamiseksi.