SE9601091L - Användning av en proteinsubstans för bindning av steroid-liknande molekyler - Google Patents

Användning av en proteinsubstans för bindning av steroid-liknande molekyler

Info

Publication number: SE9601091L
Authority: SE; Sweden
Prior art keywords: bile; treatment; steroid; beneficial; injury
Prior art date: 1996-03-21

Application number

SE9601091A

Other languages

English (en)

Other versions

SE9601091D0 (sv

Inventor

Joyce Carlson

Sabina-Marija Janciauskiene

Original Assignee

Joyce Carlson

Sabina Marija Janciauskiene

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-21

Filing date

1996-03-21

Publication date

1997-09-22

1996-03-21 Application filed by Joyce Carlson, Sabina Marija Janciauskiene filed Critical Joyce Carlson

1996-03-21 Priority to SE9601091A priority Critical patent/SE9601091L/sv

1996-03-21 Publication of SE9601091D0 publication Critical patent/SE9601091D0/sv

1997-03-20 Priority to EP97914726A priority patent/EP0904102A1/en

1997-03-20 Priority to PCT/SE1997/000465 priority patent/WO1997034628A1/en

1997-03-20 Priority to AU21864/97A priority patent/AU2186497A/en

1997-09-22 Publication of SE9601091L publication Critical patent/SE9601091L/sv

Links

230000003637 steroidlike Effects 0.000 title abstract 2
239000000126 substance Substances 0.000 title abstract 2
102000004169 proteins and genes Human genes 0.000 title 1
108090000623 proteins and genes Proteins 0.000 title 1
239000003613 bile acid Substances 0.000 abstract 4
230000009286 beneficial effect Effects 0.000 abstract 3
230000015572 biosynthetic process Effects 0.000 abstract 2
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
230000008030 elimination Effects 0.000 abstract 2
238000003379 elimination reaction Methods 0.000 abstract 2
230000002496 gastric effect Effects 0.000 abstract 2
230000000968 intestinal effect Effects 0.000 abstract 2
150000003431 steroids Chemical class 0.000 abstract 2
HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 1
206010069703 Bile acid malabsorption Diseases 0.000 abstract 1
206010008635 Cholestasis Diseases 0.000 abstract 1
206010012735 Diarrhoea Diseases 0.000 abstract 1
206010018364 Glomerulonephritis Diseases 0.000 abstract 1
101000823116 Homo sapiens Alpha-1-antitrypsin Proteins 0.000 abstract 1
208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
208000022559 Inflammatory bowel disease Diseases 0.000 abstract 1
206010067125 Liver injury Diseases 0.000 abstract 1
241001465754 Metazoa Species 0.000 abstract 1
206010056528 Neonatal cholestasis Diseases 0.000 abstract 1
208000012868 Overgrowth Diseases 0.000 abstract 1
206010057969 Reflux gastritis Diseases 0.000 abstract 1
206010047115 Vasculitis Diseases 0.000 abstract 1
208000027418 Wounds and injury Diseases 0.000 abstract 1
230000001580 bacterial effect Effects 0.000 abstract 1
235000012000 cholesterol Nutrition 0.000 abstract 1
230000000295 complement effect Effects 0.000 abstract 1
230000006378 damage Effects 0.000 abstract 1
230000007547 defect Effects 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
231100000753 hepatic injury Toxicity 0.000 abstract 1
102000051631 human SERPINA1 Human genes 0.000 abstract 1
230000002209 hydrophobic effect Effects 0.000 abstract 1
208000014674 injury Diseases 0.000 abstract 1
235000013336 milk Nutrition 0.000 abstract 1
239000008267 milk Substances 0.000 abstract 1
210000004080 milk Anatomy 0.000 abstract 1
230000001681 protective effect Effects 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
208000037816 tissue injury Diseases 0.000 abstract 1
230000009261 transgenic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8125—Alpha-1-antitrypsin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/20—Milk; Whey; Colostrum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Cell Biology (AREA)
Developmental Biology & Embryology (AREA)
Virology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

SE9601091A 1996-03-21 1996-03-21 Användning av en proteinsubstans för bindning av steroid-liknande molekyler SE9601091L (sv)

Priority Applications (4)

Application Number	Priority Date	Filing Date	Title
SE9601091A SE9601091L (sv)	1996-03-21	1996-03-21	Användning av en proteinsubstans för bindning av steroid-liknande molekyler
EP97914726A EP0904102A1 (en)	1996-03-21	1997-03-20	Milk of transgenic animals containing human alpha 1-antitrypsin and use of human alpha 1-antitrypsin to treat bile acid related diseases
PCT/SE1997/000465 WO1997034628A1 (en)	1996-03-21	1997-03-20	Milk of transgenic animals containing human alpha1-antitrypsin and use of human alpha1-antitrypsin to treat bile acid related diseases
AU21864/97A AU2186497A (en)	1996-03-21	1997-03-20	Milk of transgenic animals containing human alpha1-antitrypsin and use of human alpha1-antitrypsin to treat bile acid related diseases

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9601091A SE9601091L (sv)	1996-03-21	1996-03-21	Användning av en proteinsubstans för bindning av steroid-liknande molekyler

Publications (2)

Publication Number	Publication Date
SE9601091D0 SE9601091D0 (sv)	1996-03-21
SE9601091L true SE9601091L (sv)	1997-09-22

Family

ID=20401887

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE9601091A SE9601091L (sv)	1996-03-21	1996-03-21	Användning av en proteinsubstans för bindning av steroid-liknande molekyler

Country Status (4)

Country	Link
EP (1)	EP0904102A1 (sv)
AU (1)	AU2186497A (sv)
SE (1)	SE9601091L (sv)
WO (1)	WO1997034628A1 (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2351943A1 (en) *	1998-11-19	2000-06-02	Pharming Intellectual Property B.V.	Stabilisation of milk from transgenic animals
US7030289B2 (en)	1998-11-19	2006-04-18	Ppl Therapeutics (Scotland) Ltd	Stabilization of milk from transgenic animals
EP1150699A4 (en) *	1999-02-01	2004-06-30	John Lezdey	TREATMENT OF BLADDER AND GASTROINTESTINAL MASTO CYTOSIS
AUPP971399A0 (en) *	1999-04-12	1999-05-06	Life Therapeutics Limited	Separation of plasma components
WO2009008120A1 (ja) *	2007-07-12	2009-01-15	Yuichi Sugiyama	膜タンパク質の安定化剤及び安定化方法
ES2902404T3 (es)	2016-02-22	2022-03-28	Novartis Ag	Métodos para utilizar agonistas de fxr.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4873316A (en) *	1987-06-23	1989-10-10	Biogen, Inc.	Isolation of exogenous recombinant proteins from the milk of transgenic mammals
US5439824A (en) *	1993-05-06	1995-08-08	The United States Of America	Increased expression of α-1-antitrypsin in expression vectors through the inclusion of intron II

1996
- 1996-03-21 SE SE9601091A patent/SE9601091L/sv not_active Application Discontinuation
1997
- 1997-03-20 EP EP97914726A patent/EP0904102A1/en not_active Withdrawn
- 1997-03-20 AU AU21864/97A patent/AU2186497A/en not_active Abandoned
- 1997-03-20 WO PCT/SE1997/000465 patent/WO1997034628A1/en not_active Ceased

Also Published As

Publication number	Publication date
EP0904102A1 (en)	1999-03-31
SE9601091D0 (sv)	1996-03-21
WO1997034628A1 (en)	1997-09-25
AU2186497A (en)	1997-10-10

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Legal Events

Date	Code	Title	Description
2003-01-07	NAV	Patent application has lapsed