SG10201700973YA - Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineering - Google Patents
Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineeringInfo
- Publication number
- SG10201700973YA SG10201700973YA SG10201700973YA SG10201700973YA SG10201700973YA SG 10201700973Y A SG10201700973Y A SG 10201700973YA SG 10201700973Y A SG10201700973Y A SG 10201700973YA SG 10201700973Y A SG10201700973Y A SG 10201700973YA SG 10201700973Y A SG10201700973Y A SG 10201700973YA
- Authority
- SG
- Singapore
- Prior art keywords
- manufacturing
- scaffold
- compositions
- methods
- living cells
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 2
- 239000000017 hydrogel Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000011859 microparticle Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/222—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/08—Methods for forming porous structures using a negative form which is filled and then removed by pyrolysis or dissolution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261680854P | 2012-08-08 | 2012-08-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201700973YA true SG10201700973YA (en) | 2017-04-27 |
Family
ID=50068421
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201700973YA SG10201700973YA (en) | 2012-08-08 | 2013-07-26 | Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineering |
| SG11201500188YA SG11201500188YA (en) | 2012-08-08 | 2013-07-26 | Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineering |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201500188YA SG11201500188YA (en) | 2012-08-08 | 2013-07-26 | Methods of manufacturing hydrogel microparticles having living cells, and compositions for manufacturing a scaffold for tissue engineering |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9974886B2 (fr) |
| EP (1) | EP2882465B1 (fr) |
| CN (1) | CN104582747B (fr) |
| SG (2) | SG10201700973YA (fr) |
| WO (1) | WO2014025312A1 (fr) |
Families Citing this family (86)
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| WO2012019168A2 (fr) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Acides nucléiques modifiés et leurs procédés d'utilisation |
| RU2013120302A (ru) | 2010-10-01 | 2014-11-20 | Модерна Терапьютикс, Инк. | Сконструированные нуклеиновые кислоты и способы их применения |
| EP2691101A2 (fr) | 2011-03-31 | 2014-02-05 | Moderna Therapeutics, Inc. | Administration et formulation d'acides nucléiques génétiquement modifiés |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| RU2648950C2 (ru) | 2011-10-03 | 2018-04-02 | Модерна Терапьютикс, Инк. | Модифицированные нуклеозиды, нуклеотиды и нуклеиновые кислоты и их применение |
| CN104114572A (zh) | 2011-12-16 | 2014-10-22 | 现代治疗公司 | 经修饰的核苷、核苷酸和核酸组合物 |
| US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
| AU2013243948A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins associated with human disease |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| WO2014081507A1 (fr) | 2012-11-26 | 2014-05-30 | Moderna Therapeutics, Inc. | Arn modifié à son extrémité terminale |
| EP2971010B1 (fr) | 2013-03-14 | 2020-06-10 | ModernaTX, Inc. | Formulation et administration de compositions de nucléosides, de nucléotides, et d'acides nucléiques modifiés |
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| CN114410574B (zh) * | 2022-03-24 | 2024-02-06 | 烟台鼎昊生物科技有限公司 | 一种软骨细胞体外三维培养体系的制备方法 |
| CN117531046A (zh) * | 2022-08-02 | 2024-02-09 | 上海中医药大学 | 一种卵清蛋白光交联水凝胶的制备方法 |
| DE102022120500B3 (de) | 2022-08-15 | 2023-10-12 | FILK Freiberg Institute gGmbH | Verfahren und Vorrichtung zur Herstellung von Hohlkugeln aus Kollagen und Kollagenderivaten und Hohlkugeln aus Kollagen und Gelatine |
| CN116077736A (zh) * | 2022-09-26 | 2023-05-09 | 四川大学 | 基于多孔明胶复合微球的可注射骨修复支架及其制备方法 |
| CN115553469B (zh) * | 2022-09-27 | 2023-10-03 | 六安益普罗科技有限公司 | 一种胃黏膜粘附的益生菌缓释微球、制备方法及用于制备抗幽门螺旋杆菌或缓解胃黏膜炎的药物 |
| CN116650729A (zh) * | 2023-05-25 | 2023-08-29 | 扬州大学 | 一种新型的软骨基质仿生材料的制备方法 |
| TWI835690B (zh) * | 2023-07-26 | 2024-03-11 | 臺北醫學大學 | 用於治療節段性骨缺損的可注射型水膠 |
| CN116870243B (zh) * | 2023-08-10 | 2024-01-19 | 广州创赛生物医用材料有限公司 | 一种具有止血抗炎作用的水凝胶及其制备方法和应用 |
| DE102023131356A1 (de) * | 2023-11-09 | 2025-05-15 | INM - Leibniz-Institut für Neue Materialien gemeinnützige Gesellschaft mit beschränkter Haftung | Lebendes Kompositmaterial für medizinische Produkte |
| CN117618671B (zh) * | 2023-12-13 | 2025-03-25 | 烟台德胜海洋生物科技有限公司 | 胶原蛋白填充剂、制备方法及其应用 |
| CN117547554B (zh) * | 2024-01-12 | 2024-05-14 | 山东康根源生物集团有限公司 | 一种间充质干细胞修复制剂及其制备方法 |
| EP4628528A1 (fr) * | 2024-04-05 | 2025-10-08 | Nutrition & Biosciences USA 1, LLC | Particules d'hydrogel d'alginate pour des applications de culture cellulaire |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4798786A (en) * | 1982-05-06 | 1989-01-17 | Stolle Research And Development Corporation | Living cells encapsulated in crosslinked protein |
| DE10042484A1 (de) * | 2000-08-29 | 2002-03-28 | Merck Patent Gmbh | Verfahren zur Herstellung von humanen Knorpelimplantaten mittels in vitro gezüchteter Chondrozyten |
| EP2229147A2 (fr) * | 2007-12-03 | 2010-09-22 | The Johns Hopkins University | Procédés de synthèse et d'utilisation de chimiosphères |
| SG185988A1 (en) * | 2009-05-15 | 2012-12-28 | Univ Nanyang Tech | Composition for manufacturing a scaffold for tissue engineering, and a method of making it |
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2013
- 2013-07-26 US US14/420,278 patent/US9974886B2/en active Active
- 2013-07-26 SG SG10201700973YA patent/SG10201700973YA/en unknown
- 2013-07-26 EP EP13828142.3A patent/EP2882465B1/fr not_active Not-in-force
- 2013-07-26 CN CN201380042205.XA patent/CN104582747B/zh active Active
- 2013-07-26 SG SG11201500188YA patent/SG11201500188YA/en unknown
- 2013-07-26 WO PCT/SG2013/000312 patent/WO2014025312A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP2882465A1 (fr) | 2015-06-17 |
| EP2882465B1 (fr) | 2019-05-08 |
| US20150217024A1 (en) | 2015-08-06 |
| CN104582747B (zh) | 2016-12-21 |
| CN104582747A (zh) | 2015-04-29 |
| WO2014025312A1 (fr) | 2014-02-13 |
| EP2882465A4 (fr) | 2016-04-06 |
| US9974886B2 (en) | 2018-05-22 |
| SG11201500188YA (en) | 2015-02-27 |
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