SG11201401794YA - Selective androgen receptor modulators - Google Patents

Selective androgen receptor modulators

Info

Publication number
SG11201401794YA
SG11201401794YA SG11201401794YA SG11201401794YA SG11201401794YA SG 11201401794Y A SG11201401794Y A SG 11201401794YA SG 11201401794Y A SG11201401794Y A SG 11201401794YA SG 11201401794Y A SG11201401794Y A SG 11201401794YA SG 11201401794Y A SG11201401794Y A SG 11201401794YA
Authority
SG
Singapore
Prior art keywords
androgen receptor
receptor modulators
selective androgen
selective
modulators
Prior art date
Application number
SG11201401794YA
Inventor
Prabhakar Kondaji Jadhav
Ashraf Saeed
Jonathan Edward Green
Venkatesh Krishnan
Donald Paul Matthews
Gregory Alan Stephenson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47046879&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201401794Y(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SG11201401794YA publication Critical patent/SG11201401794YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06Anabolic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26Androgens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/22Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SG11201401794YA 2011-10-13 2012-10-05 Selective androgen receptor modulators SG11201401794YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161546711P 2011-10-13 2011-10-13
PCT/US2012/058824 WO2013055577A1 (en) 2011-10-13 2012-10-05 Selective androgen receptor modulators

Publications (1)

Publication Number Publication Date
SG11201401794YA true SG11201401794YA (en) 2014-09-26

Family

ID=47046879

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201401794YA SG11201401794YA (en) 2011-10-13 2012-10-05 Selective androgen receptor modulators

Country Status (28)

Country Link
US (1) US8658693B2 (en)
EP (1) EP2766350B1 (en)
JP (1) JP6002228B2 (en)
KR (1) KR20140067102A (en)
CN (1) CN103842348B (en)
AP (1) AP2014007548A0 (en)
AR (1) AR088082A1 (en)
AU (1) AU2012321113B2 (en)
BR (1) BR112014008668A2 (en)
CA (1) CA2847889A1 (en)
CL (1) CL2014000895A1 (en)
CO (1) CO6910195A2 (en)
CR (1) CR20140156A (en)
DO (1) DOP2014000075A (en)
EA (1) EA201490519A1 (en)
EC (1) ECSP14013305A (en)
ES (1) ES2626820T3 (en)
GT (1) GT201400067A (en)
IL (1) IL231440A0 (en)
MX (1) MX2014004558A (en)
PE (1) PE20141669A1 (en)
PH (1) PH12014500808A1 (en)
PL (1) PL2766350T3 (en)
PT (1) PT2766350T (en)
SG (1) SG11201401794YA (en)
TN (1) TN2014000136A1 (en)
TW (1) TWI449686B (en)
WO (1) WO2013055577A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140045856A1 (en) 2012-07-31 2014-02-13 Boehringer Ingelheim International Gmbh 4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes
TW201534586A (en) * 2013-06-11 2015-09-16 Orion Corp Novel CYP17 inhibitors/antiandrogens
CA2929742C (en) 2013-12-04 2022-09-20 Evotec International Gmbh Sulfoximine substituted quinazolines for pharmaceutical compositions
US9682960B2 (en) 2013-12-19 2017-06-20 Endorecherche, Inc. Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety
EP3140300B1 (en) 2014-05-07 2019-08-14 Evotec International GmbH Sulfoximine substituted quinazolines for pharmaceutical compositions
CN109803968A (en) 2016-08-15 2019-05-24 辉瑞公司 Pyridopyrimidinone CDK2/4/6 inhibitor
MX389592B (en) 2016-09-02 2025-03-20 Suven Life Sciences Ltd Muscarinic m1 receptor positive allosteric modulators
US11076596B2 (en) 2017-09-18 2021-08-03 Basf Se Substituted trifluoromethyloxadiazoles for combating phytopathogenic fungi
TWI702219B (en) * 2018-07-12 2020-08-21 美商美國禮來大藥廠 Selective estrogen receptor degraders
JP7778095B2 (en) * 2020-06-24 2025-12-01 セルジーン コーポレーション Cereblon-binding compounds, compositions thereof, and methods of treatment therewith
WO2025104624A1 (en) * 2023-11-14 2025-05-22 Pfizer Inc. Synthesis of 1,5-anhydro-3-({5-chloro-4-[4-fluoro-2-(2-hydroxypropan-2-yl)-1-(propan-2-yl)-1h-benzimidazol-6-yl]pyrimidin-2-yl}amino)-2,3-dideoxy-d-threo-pentitol

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594405A (en) * 1968-05-17 1971-07-20 Du Pont Substituted pyranyl anilines as plant growth modifiers
EP1256578B1 (en) * 2001-05-11 2006-01-11 Pfizer Products Inc. Thiazole derivatives and their use as cdk inhibitors
US8519158B2 (en) * 2004-03-12 2013-08-27 Ligand Pharmaceuticals Incorporated Androgen receptor modulator compounds and methods
DK1891038T3 (en) * 2005-05-13 2009-01-19 Lilly Co Eli Substituted n-arylpyrrolidines as selective androgen receptor modulators
BRPI0619208A2 (en) * 2005-11-30 2011-09-20 Astellas Pharma Inc 2-aminobenzamide derivative c07d 307/14 c07d 307/22 c07d 309/14 c07d 319/12 c07d 401/12 c07d 405/12 c07d 413/12 c07d 417/12
EP2146967A2 (en) * 2007-04-16 2010-01-27 Serenex, Inc. Tetrahydroindole and tetrahydroindazole derivatives
US8190467B2 (en) * 2007-10-19 2012-05-29 Michelle Letendre-Hedlund Methods of identifying environmentally friendly businesses or individuals
ES2488990T3 (en) * 2008-02-22 2014-09-01 Radius Health, Inc. Selective androgen receptor modulators

Also Published As

Publication number Publication date
TN2014000136A1 (en) 2015-07-01
JP6002228B2 (en) 2016-10-05
US8658693B2 (en) 2014-02-25
IL231440A0 (en) 2014-04-30
CN103842348A (en) 2014-06-04
KR20140067102A (en) 2014-06-03
AU2012321113B2 (en) 2015-07-09
AP2014007548A0 (en) 2014-03-31
CL2014000895A1 (en) 2014-08-22
CR20140156A (en) 2014-05-16
MX2014004558A (en) 2014-08-01
TWI449686B (en) 2014-08-21
BR112014008668A2 (en) 2017-04-25
EP2766350A1 (en) 2014-08-20
ES2626820T3 (en) 2017-07-26
CN103842348B (en) 2015-08-19
PE20141669A1 (en) 2014-11-08
GT201400067A (en) 2015-02-27
EA201490519A1 (en) 2014-09-30
ECSP14013305A (en) 2014-05-31
DOP2014000075A (en) 2014-06-01
EP2766350B1 (en) 2017-04-05
PH12014500808A1 (en) 2019-07-03
PT2766350T (en) 2017-05-22
AR088082A1 (en) 2014-05-07
PL2766350T3 (en) 2017-08-31
JP2014530818A (en) 2014-11-20
TW201329026A (en) 2013-07-16
US20130217762A1 (en) 2013-08-22
WO2013055577A1 (en) 2013-04-18
CA2847889A1 (en) 2013-04-18
CO6910195A2 (en) 2014-03-31
AU2012321113A1 (en) 2014-03-27

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