SG11201406447SA - (r) -nifuratel, its use for the treatment of infections and synthesis of (r) and (s) -nifuratel - Google Patents

(r) -nifuratel, its use for the treatment of infections and synthesis of (r) and (s) -nifuratel

Info

Publication number: SG11201406447SA
Authority: SG; Singapore
Prior art keywords: nifuratel; infections; synthesis; treatment
Prior art date: 2012-05-11

Application number

SG11201406447SA

Other languages

English (en)

Inventor

Stefania Gagliardi

Alessandra Consonni

Federico Mailland

Anna Bulgheroni

Original Assignee

Polichem Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-05-11

Filing date

2013-03-13

Publication date

2014-11-27

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47846051&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201406447S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2013-03-13 Application filed by Polichem Sa filed Critical Polichem Sa

2014-11-27 Publication of SG11201406447SA publication Critical patent/SG11201406447SA/en

Links

229960002136 nifuratel Drugs 0.000 title 2
230000015572 biosynthetic process Effects 0.000 title 1
208000015181 infectious disease Diseases 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C241/00—Preparation of compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C241/02—Preparation of hydrazines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Tropical Medicine & Parasitology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Gynecology & Obstetrics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

SG11201406447SA 2012-05-11 2013-03-13 (r) -nifuratel, its use for the treatment of infections and synthesis of (r) and (s) -nifuratel SG11201406447SA (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP20120167640 EP2662371A1 (fr)	2012-05-11	2012-05-11	(R)-nifuratel et synthèse de (R) et (S)-nifuratel
PCT/EP2013/055078 WO2013167295A1 (fr)	2012-05-11	2013-03-13	(r)-nifuratel, son utilisation pour le traitement d'infections et synthèse de (r) et (s)-nifuratel

Publications (1)

Publication Number	Publication Date
SG11201406447SA true SG11201406447SA (en)	2014-11-27

Family

ID=47846051

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SG11201406447SA SG11201406447SA (en)	2012-05-11	2013-03-13	(r) -nifuratel, its use for the treatment of infections and synthesis of (r) and (s) -nifuratel
SG10201608485XA SG10201608485XA (en)	2012-05-11	2013-03-13	(r) -nifuratel, its use for the treatment of infections and synthesis of (r) and (s) -nifuratel

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SG10201608485XA SG10201608485XA (en)	2012-05-11	2013-03-13	(r) -nifuratel, its use for the treatment of infections and synthesis of (r) and (s) -nifuratel

Country Status (27)

Country	Link
US (2)	US9284306B2 (fr)
EP (2)	EP2662371A1 (fr)
JP (1)	JP2015515998A (fr)
KR (1)	KR20150008871A (fr)
CN (1)	CN104379580A (fr)
AU (1)	AU2013258385A1 (fr)
BR (1)	BR112014027953A2 (fr)
CA (1)	CA2869827A1 (fr)
CL (1)	CL2014002951A1 (fr)
CO (1)	CO7131368A2 (fr)
CR (1)	CR20140505A (fr)
DO (1)	DOP2014000252A (fr)
EA (1)	EA201492081A1 (fr)
EC (1)	ECSP14026432A (fr)
GE (2)	GEP201706626B (fr)
HK (1)	HK1202539A1 (fr)
IL (1)	IL235429A0 (fr)
IN (1)	IN2014DN09256A (fr)
MA (1)	MA20150279A1 (fr)
MX (1)	MX2014013759A (fr)
NZ (1)	NZ700752A (fr)
PE (1)	PE20150167A1 (fr)
PH (2)	PH12014502500B1 (fr)
SG (2)	SG11201406447SA (fr)
TN (1)	TN2014000430A1 (fr)
WO (1)	WO2013167295A1 (fr)
ZA (1)	ZA201407596B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN108254453A (zh) *	2016-12-28	2018-07-06	苏州电器科学研究院股份有限公司	一种有效测定塑料制品中邻苯二甲酸酯含量的检测方法
EP3684773B1 (fr)	2017-09-20	2026-04-29	pH Pharma Co., Ltd.	Analogues de thailanstatine
CN108760950B (zh) *	2018-04-25	2022-07-15	国检测试控股集团京诚检测有限公司	一种测定硝基呋喃代谢物的方法
CN111892557B (zh) *	2019-05-05	2022-11-08	河北圣泰材料股份有限公司	哌嗪类成膜离子液体的合成方法
CN110672765B (zh) *	2019-10-11	2022-03-18	温州海鹤药业有限公司	一种定量检测硝呋太尔中顺式异构体杂质的方法
CN112457304B (zh) *	2020-12-07	2022-03-11	中国药科大学	一种硝呋太尔的制备方法
CN113828243B (zh) *	2021-09-14	2022-06-28	南京南大药业有限责任公司	一种硝呋太尔制霉菌素栓制造方法及设备
KR20260012304A (ko)	2023-04-17	2026-01-26	피크 바이오, 인크.	항체 및 항체-약물 접합체 및 사용 방법 및 합성 공정 및 중간체
CN116947838B (zh) *	2023-07-25	2025-08-19	北京金城泰尔制药有限公司沧州分公司	高纯度硝呋太尔的生产方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE635608A (fr)	1962-08-01
CN100506820C (zh)	2006-03-16	2009-07-01	韩志强	(s)-硝呋太尔,其制备方法和应用
CN100516063C (zh) *	2006-03-16	2009-07-22	韩志强	硝呋太尔的生产方法
CN101434584A (zh) *	2007-11-15	2009-05-20	中山大学	具有抗菌活性的手性噁唑烷酮类化合物
EP2243482A1 (fr) *	2009-04-20	2010-10-27	Polichem SA	Utilisation de nifuratel pour traiter des infections provoquées par des espèces d'Atopobium

2012
- 2012-05-11 EP EP20120167640 patent/EP2662371A1/fr not_active Withdrawn
2013
- 2013-03-13 NZ NZ700752A patent/NZ700752A/en not_active IP Right Cessation
- 2013-03-13 MX MX2014013759A patent/MX2014013759A/es unknown
- 2013-03-13 SG SG11201406447SA patent/SG11201406447SA/en unknown
- 2013-03-13 SG SG10201608485XA patent/SG10201608485XA/en unknown
- 2013-03-13 CA CA 2869827 patent/CA2869827A1/fr not_active Abandoned
- 2013-03-13 AU AU2013258385A patent/AU2013258385A1/en not_active Abandoned
- 2013-03-13 WO PCT/EP2013/055078 patent/WO2013167295A1/fr not_active Ceased
- 2013-03-13 BR BR112014027953A patent/BR112014027953A2/pt not_active IP Right Cessation
- 2013-03-13 PE PE2014001944A patent/PE20150167A1/es not_active Application Discontinuation
- 2013-03-13 EA EA201492081A patent/EA201492081A1/ru unknown
- 2013-03-13 KR KR20147031517A patent/KR20150008871A/ko not_active Withdrawn
- 2013-03-13 EP EP13708840.7A patent/EP2847189A1/fr not_active Withdrawn
- 2013-03-13 MA MA37496A patent/MA20150279A1/fr unknown
- 2013-03-13 US US14/400,071 patent/US9284306B2/en not_active Expired - Fee Related
- 2013-03-13 IN IN9256DEN2014 patent/IN2014DN09256A/en unknown
- 2013-03-13 GE GEAP201313967A patent/GEP201706626B/en unknown
- 2013-03-13 CN CN201380022803.0A patent/CN104379580A/zh active Pending
- 2013-03-13 GE GEAP201313660A patent/GEP201606595B/en unknown
- 2013-03-13 HK HK15103057.7A patent/HK1202539A1/xx unknown
- 2013-03-13 JP JP2015510685A patent/JP2015515998A/ja active Pending
2014
- 2014-10-16 TN TN2014000430A patent/TN2014000430A1/fr unknown
- 2014-10-20 ZA ZA2014/07596A patent/ZA201407596B/en unknown
- 2014-10-30 CL CL2014002951A patent/CL2014002951A1/es unknown
- 2014-10-30 IL IL235429A patent/IL235429A0/en unknown
- 2014-11-03 CR CR20140505A patent/CR20140505A/es unknown
- 2014-11-07 DO DO2014000252A patent/DOP2014000252A/es unknown
- 2014-11-10 PH PH12014502500A patent/PH12014502500B1/en unknown
- 2014-11-11 CO CO14248543A patent/CO7131368A2/es unknown
- 2014-11-11 EC ECIEPI201426432A patent/ECSP14026432A/es unknown
2015
- 2015-01-28 US US14/607,464 patent/US9067927B2/en not_active Expired - Fee Related
- 2015-09-24 PH PH12015502241A patent/PH12015502241A1/en unknown

Also Published As

Publication number	Publication date
PE20150167A1 (es)	2015-02-07
CA2869827A1 (fr)	2013-11-14
US9284306B2 (en)	2016-03-15
EA201492081A1 (ru)	2015-06-30
GEP201706626B (en)	2017-02-10
WO2013167295A1 (fr)	2013-11-14
NZ700752A (en)	2016-02-26
KR20150008871A (ko)	2015-01-23
IN2014DN09256A (fr)	2015-07-10
EP2847189A1 (fr)	2015-03-18
ZA201407596B (en)	2016-05-25
SG10201608485XA (en)	2016-12-29
IL235429A0 (en)	2014-12-31
JP2015515998A (ja)	2015-06-04
MA20150279A1 (fr)	2015-08-31
CN104379580A (zh)	2015-02-25
PH12014502500A1 (en)	2014-12-15
DOP2014000252A (es)	2014-12-31
BR112014027953A2 (pt)	2018-02-06
CL2014002951A1 (es)	2014-12-26
PH12015502241A1 (en)	2016-08-15
PH12014502500B1 (en)	2014-12-15
AU2013258385A1 (en)	2014-10-30
EP2662371A1 (fr)	2013-11-13
GEP201606595B (en)	2017-01-10
CR20140505A (es)	2015-02-06
MX2014013759A (es)	2015-08-07
US9067927B2 (en)	2015-06-30
US20150119431A1 (en)	2015-04-30
HK1202539A1 (en)	2015-10-02
CO7131368A2 (es)	2014-12-01
TN2014000430A1 (en)	2016-03-30
ECSP14026432A (es)	2015-09-30
US20150148547A1 (en)	2015-05-28

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