SG11202004649SA - Sequencing of nucleic acids by emergence - Google Patents
Sequencing of nucleic acids by emergenceInfo
- Publication number
- SG11202004649SA SG11202004649SA SG11202004649SA SG11202004649SA SG11202004649SA SG 11202004649S A SG11202004649S A SG 11202004649SA SG 11202004649S A SG11202004649S A SG 11202004649SA SG 11202004649S A SG11202004649S A SG 11202004649SA SG 11202004649S A SG11202004649S A SG 11202004649SA
- Authority
- SG
- Singapore
- Prior art keywords
- emergence
- sequencing
- nucleic acids
- nucleic
- acids
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 238000012163 sequencing technique Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/113—Heteroduplex formation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/173—Nucleic acid detection characterized by the use of physical, structural and functional properties staining/intercalating agent, e.g. ethidium bromide
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Theoretical Computer Science (AREA)
- Bioinformatics & Computational Biology (AREA)
- Data Mining & Analysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Evolutionary Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Software Systems (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Bioethics (AREA)
- Artificial Intelligence (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Evolutionary Computation (AREA)
- Databases & Information Systems (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762591850P | 2017-11-29 | 2017-11-29 | |
| PCT/US2018/063162 WO2019108853A1 (en) | 2017-11-29 | 2018-11-29 | Sequencing of nucleic acids by emergence |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202004649SA true SG11202004649SA (en) | 2020-06-29 |
Family
ID=66664243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202004649SA SG11202004649SA (en) | 2017-11-29 | 2018-11-29 | Sequencing of nucleic acids by emergence |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US10982260B2 (de) |
| EP (1) | EP3717645A4 (de) |
| JP (1) | JP2021503969A (de) |
| KR (1) | KR20200105660A (de) |
| CN (1) | CN111566211A (de) |
| AU (1) | AU2018375160A1 (de) |
| CA (1) | CA3084554A1 (de) |
| SG (1) | SG11202004649SA (de) |
| WO (1) | WO2019108853A1 (de) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11427867B2 (en) * | 2017-11-29 | 2022-08-30 | Xgenomes Corp. | Sequencing by emergence |
| US20200059506A1 (en) | 2018-08-14 | 2020-02-20 | Triad National Security, Llc | Data transmission framing |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| US12529094B2 (en) | 2018-12-10 | 2026-01-20 | 10X Genomics, Inc. | Imaging system hardware |
| WO2020123316A2 (en) | 2018-12-10 | 2020-06-18 | 10X Genomics, Inc. | Methods for determining a location of a biological analyte in a biological sample |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| CA3135206A1 (en) | 2019-04-29 | 2020-11-05 | Pierre Indermuhle | Methods and systems for integrated on-chip single-molecule detection |
| EP3976828A4 (de) * | 2019-05-29 | 2023-06-28 | XGenomes Corp. | Sequenzierung nach emergenz |
| WO2020243579A1 (en) | 2019-05-30 | 2020-12-03 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| CN110760574B (zh) * | 2019-10-14 | 2023-06-06 | 芯盟科技有限公司 | 测定碱基的装置及方法 |
| WO2021092433A2 (en) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Enhancing specificity of analyte binding |
| CN115135984B (zh) | 2019-12-23 | 2025-12-23 | 10X基因组学有限公司 | 可逆固定试剂及其使用方法 |
| ES2982420T3 (es) | 2019-12-23 | 2024-10-16 | 10X Genomics Inc | Métodos para el análisis espacial mediante el uso de la ligazón con plantilla de ARN |
| EP4081656A1 (de) | 2019-12-23 | 2022-11-02 | 10X Genomics, Inc. | Zusammensetzungen und verfahren zur verwendung von fixierten biologischen proben bei partitionsbasierten tests |
| US12365942B2 (en) | 2020-01-13 | 2025-07-22 | 10X Genomics, Inc. | Methods of decreasing background on a spatial array |
| US12405264B2 (en) | 2020-01-17 | 2025-09-02 | 10X Genomics, Inc. | Electrophoretic system and method for analyte capture |
| US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
| US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
| US20210230681A1 (en) | 2020-01-24 | 2021-07-29 | 10X Genomics, Inc. | Methods for spatial analysis using proximity ligation |
| US12076701B2 (en) | 2020-01-31 | 2024-09-03 | 10X Genomics, Inc. | Capturing oligonucleotides in spatial transcriptomics |
| US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
| US12110541B2 (en) | 2020-02-03 | 2024-10-08 | 10X Genomics, Inc. | Methods for preparing high-resolution spatial arrays |
| US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
| WO2021158925A1 (en) | 2020-02-07 | 2021-08-12 | 10X Genomics, Inc. | Quantitative and automated permeabilization performance evaluation for spatial transcriptomics |
| US12281357B1 (en) | 2020-02-14 | 2025-04-22 | 10X Genomics, Inc. | In situ spatial barcoding |
| EP4139485B1 (de) | 2020-04-22 | 2023-09-06 | 10X Genomics, Inc. | Verfahren zur räumlichen analyse unter verwendung von gezieltem rna-abbau |
| EP4414459B1 (de) | 2020-05-22 | 2025-09-03 | 10X Genomics, Inc. | Simultane räumlich-zeitliche messung der genexpression und der zellaktivität |
| EP4153776B1 (de) | 2020-05-22 | 2025-03-05 | 10X Genomics, Inc. | Räumliche analyse zur erkennung von sequenzvarianten |
| WO2021242834A1 (en) | 2020-05-26 | 2021-12-02 | 10X Genomics, Inc. | Method for resetting an array |
| US12031177B1 (en) | 2020-06-04 | 2024-07-09 | 10X Genomics, Inc. | Methods of enhancing spatial resolution of transcripts |
| EP4421186B1 (de) | 2020-06-08 | 2025-08-13 | 10X Genomics, Inc. | Verfahren zur bestimmung eines chirurgischen randes und verfahren zur verwendung davon |
| ES2994976T3 (en) | 2020-06-25 | 2025-02-05 | 10X Genomics Inc | Spatial analysis of dna methylation |
| US11981960B1 (en) | 2020-07-06 | 2024-05-14 | 10X Genomics, Inc. | Spatial analysis utilizing degradable hydrogels |
| US12209280B1 (en) | 2020-07-06 | 2025-01-28 | 10X Genomics, Inc. | Methods of identifying abundance and location of an analyte in a biological sample using second strand synthesis |
| US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
| US11981958B1 (en) | 2020-08-20 | 2024-05-14 | 10X Genomics, Inc. | Methods for spatial analysis using DNA capture |
| US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
| US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
| EP4729631A2 (de) | 2020-12-21 | 2026-04-22 | 10X Genomics, Inc. | Verfahren, zusammensetzungen und systeme zur erfassung von sonden und/oder barcodes |
| EP4305196B1 (de) | 2021-04-14 | 2025-04-02 | 10X Genomics, Inc. | Verfahren zur messung der fehllokalisierung eines analyten |
| EP4320271B1 (de) | 2021-05-06 | 2025-03-19 | 10X Genomics, Inc. | Verfahren zur erhöhung der auflösung von räumlicher analyse |
| WO2022256503A1 (en) | 2021-06-03 | 2022-12-08 | 10X Genomics, Inc. | Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis |
| WO2023028232A2 (en) * | 2021-08-27 | 2023-03-02 | Apton Biosystems, Inc. | Compositions and methods for densely-packed analyte analysis |
| WO2023034489A1 (en) | 2021-09-01 | 2023-03-09 | 10X Genomics, Inc. | Methods, compositions, and kits for blocking a capture probe on a spatial array |
| WO2023086880A1 (en) | 2021-11-10 | 2023-05-19 | 10X Genomics, Inc. | Methods, compositions, and kits for determining the location of an analyte in a biological sample |
| WO2023102118A2 (en) | 2021-12-01 | 2023-06-08 | 10X Genomics, Inc. | Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis |
| CN113881753B (zh) * | 2021-12-08 | 2022-02-18 | 南京邮电大学 | 一种非诊断目的的基因定位方法 |
| CN116883308B (zh) * | 2022-03-28 | 2025-11-28 | 深圳华大生命科学研究院 | 核酸完整性判定的方法和系统 |
| EP4482979B1 (de) | 2022-11-09 | 2025-10-01 | 10X Genomics, Inc. | Verfahren, zusammensetzungen und kits zur bestimmung der position mehrerer analyten in einer biologischen probe |
| US20260009070A1 (en) * | 2022-12-16 | 2026-01-08 | Foundation Medicine, Inc. | Library preparation and analytical methods for preserving topological information of cell-free dna |
| WO2024226383A1 (en) * | 2023-04-22 | 2024-10-31 | The Regents Of The University Of California | Single cell multiomics using releasable capture probes |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2755149B1 (fr) * | 1996-10-30 | 1999-01-15 | Pasteur Institut | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
| WO1999057306A2 (en) * | 1998-05-01 | 1999-11-11 | Queen's University At Kingston | Method for diagnosing a vascular condition |
| US7071324B2 (en) * | 1998-10-13 | 2006-07-04 | Brown University Research Foundation | Systems and methods for sequencing by hybridization |
| US6221592B1 (en) | 1998-10-20 | 2001-04-24 | Wisconsin Alumi Research Foundation | Computer-based methods and systems for sequencing of individual nucleic acid molecules |
| NO986133D0 (no) * | 1998-12-23 | 1998-12-23 | Preben Lexow | FremgangsmÕte for DNA-sekvensering |
| US7585964B2 (en) | 2001-05-14 | 2009-09-08 | Cancer Genetics, Inc. | Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (FISH) |
| US20040058349A1 (en) | 2001-10-01 | 2004-03-25 | Jeffrey Van Ness | Methods for identifying nucleotides at defined positions in target nucleic acids |
| CA2513899C (en) | 2003-01-29 | 2013-03-26 | 454 Corporation | Methods of amplifying and sequencing nucleic acids |
| US7276338B2 (en) * | 2003-11-17 | 2007-10-02 | Jacobson Joseph M | Nucleotide sequencing via repetitive single molecule hybridization |
| US10081839B2 (en) * | 2005-07-29 | 2018-09-25 | Natera, Inc | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US20100068701A1 (en) * | 2008-09-12 | 2010-03-18 | Yamada N Alice | Chromosome labeling method |
| EP2569447A4 (de) * | 2010-05-14 | 2013-11-27 | Fluidigm Corp | Assays für den nachweis von genotypen, mutationen oder aneuploidie |
| GB201017905D0 (en) | 2010-10-25 | 2010-12-01 | Mir Kalim U | Preparation and analysis of samples |
| WO2014164716A1 (en) * | 2013-03-13 | 2014-10-09 | President And Fellows Of Harvard College | Methods of elongating dna |
| EP3411494B1 (de) | 2015-11-18 | 2025-08-13 | Kalim U. Mir | Hochauflösende sequenzierung |
| EP3411496A1 (de) * | 2016-02-05 | 2018-12-12 | Ludwig-Maximilians-Universität München | Molekulare identifizierung mit subnanometerortungsgenauigkeit |
-
2018
- 2018-11-29 SG SG11202004649SA patent/SG11202004649SA/en unknown
- 2018-11-29 AU AU2018375160A patent/AU2018375160A1/en not_active Abandoned
- 2018-11-29 CN CN201880086079.0A patent/CN111566211A/zh active Pending
- 2018-11-29 JP JP2020548873A patent/JP2021503969A/ja active Pending
- 2018-11-29 US US16/205,155 patent/US10982260B2/en active Active
- 2018-11-29 CA CA3084554A patent/CA3084554A1/en active Pending
- 2018-11-29 KR KR1020207018498A patent/KR20200105660A/ko not_active Ceased
- 2018-11-29 EP EP18884351.0A patent/EP3717645A4/de active Pending
- 2018-11-29 WO PCT/US2018/063162 patent/WO2019108853A1/en not_active Ceased
-
2021
- 2021-03-10 US US17/198,032 patent/US20220064712A1/en not_active Abandoned
-
2023
- 2023-06-07 US US18/330,847 patent/US20240117413A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20240117413A1 (en) | 2024-04-11 |
| US20220064712A1 (en) | 2022-03-03 |
| KR20200105660A (ko) | 2020-09-08 |
| JP2021503969A (ja) | 2021-02-15 |
| US10982260B2 (en) | 2021-04-20 |
| CA3084554A1 (en) | 2019-06-06 |
| US20190233880A1 (en) | 2019-08-01 |
| WO2019108853A1 (en) | 2019-06-06 |
| EP3717645A1 (de) | 2020-10-07 |
| AU2018375160A1 (en) | 2020-05-28 |
| EP3717645A4 (de) | 2021-09-01 |
| CN111566211A (zh) | 2020-08-21 |
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