SG11202104463YA - Anti-human fn14 antibody - Google Patents

Anti-human fn14 antibody

Info

Publication number
SG11202104463YA
SG11202104463YA SG11202104463YA SG11202104463YA SG11202104463YA SG 11202104463Y A SG11202104463Y A SG 11202104463YA SG 11202104463Y A SG11202104463Y A SG 11202104463YA SG 11202104463Y A SG11202104463Y A SG 11202104463YA SG 11202104463Y A SG11202104463Y A SG 11202104463YA
Authority
SG
Singapore
Prior art keywords
antibody
human
Prior art date
Application number
SG11202104463YA
Other languages
English (en)
Inventor
Misato Ito
Risa Kashiwagi
Masakatsu Kawakami
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of SG11202104463YA publication Critical patent/SG11202104463YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11202104463YA 2018-10-31 2019-10-30 Anti-human fn14 antibody SG11202104463YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018205995 2018-10-31
PCT/JP2019/042587 WO2020090892A1 (ja) 2018-10-31 2019-10-30 抗ヒトFn14抗体

Publications (1)

Publication Number Publication Date
SG11202104463YA true SG11202104463YA (en) 2021-05-28

Family

ID=70464144

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104463YA SG11202104463YA (en) 2018-10-31 2019-10-30 Anti-human fn14 antibody

Country Status (20)

Country Link
US (1) US12209134B2 (de)
EP (1) EP3875114A4 (de)
JP (1) JP7415939B2 (de)
KR (1) KR102922399B1 (de)
CN (1) CN112930195B (de)
AR (1) AR123671A1 (de)
AU (1) AU2019369771B2 (de)
BR (1) BR112021008424A2 (de)
CA (1) CA3117930A1 (de)
CO (1) CO2021005768A2 (de)
IL (1) IL282650B2 (de)
JO (2) JOP20210092A1 (de)
MA (1) MA54097A (de)
MX (1) MX2021004976A (de)
MY (1) MY204672A (de)
PH (1) PH12021550945A1 (de)
SG (1) SG11202104463YA (de)
TW (1) TWI843763B (de)
WO (1) WO2020090892A1 (de)
ZA (1) ZA202102879B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY204672A (en) * 2018-10-31 2024-09-09 Astellas Pharma Inc Anti-human fn14 antibody
TW202031684A (zh) 2018-12-20 2020-09-01 日商協和麒麟股份有限公司 Fn14抗體及其用途
US20240092916A1 (en) 2021-01-13 2024-03-21 Astellas Pharma Inc. MULTISPECIFIC ANTIBODY BINDING TO ActRIIA, ActRIIB, AND Fn14
WO2023062848A1 (en) * 2021-10-14 2023-04-20 Astellas Pharma Inc. Pharmaceutical composition comprising anti-human fnl4 antibody or antigen-binding fragment thereof for preventing or treating cancer
WO2024177972A2 (en) * 2023-02-20 2024-08-29 The Wistar Institute Of Anatomy And Biology Antibody-cytokine chimeras

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
KR100337069B1 (ko) 1993-03-11 2002-10-11 사이단호진가가쿠오요비겟세이리요호오겐큐쇼 항-hiv모노클로날항체
EP2298333A3 (de) 1999-12-20 2012-05-02 Immunex Corporation Tweak Rezeptor
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
EP1853312B1 (de) * 2005-03-07 2014-12-10 Genentech, Inc. Verfahren und zusammensetzungen zur modulierung von tweak- und fn14-aktivität
MEP35408A (en) * 2005-05-27 2011-02-10 Biogen Idec Inc Tweak binding antibodies
EP2545938A1 (de) 2007-08-03 2013-01-16 Abbott Biotherapeutics Corp. Therapeutische Verwendung von Anti-TWEAK-Rezeptorantikörpern
MX2010012324A (es) 2008-05-15 2011-01-14 Biogen Idec Inc Anticuerpos anti-fn14 y usos de los mismos.
US8093006B2 (en) * 2009-04-02 2012-01-10 Hoffmann-La Roche Inc. Antibodies against human tweak and uses thereof
AR081246A1 (es) 2010-05-14 2012-07-18 Abbott Lab Proteinas de union a il-1
CO6680666A2 (es) 2010-10-05 2013-05-31 Hoffmann La Roche Anticuerpos contra la tweak humana y usos de los mismos
AU2011311673B2 (en) 2010-10-05 2015-09-17 F. Hoffmann-La Roche Ag Antibodies against human TWEAK and uses thereof
AU2012225246B2 (en) 2011-03-10 2016-01-21 Omeros Corporation Generation of anti-FN14 monoclonal antibodies by ex-vivo accelerated antibody evolution
BR112014002361A2 (pt) 2011-08-02 2019-05-14 Astellas Pharma Inc. método para tratamento de câncer pelo uso combinado de fármacos
HK1198832A1 (en) 2011-08-23 2015-06-12 Transbio Ltd Fn14 binding proteins and uses thereof
JP2016000003A (ja) * 2013-04-19 2016-01-07 アステラス製薬株式会社 新規抗ヒトtweak抗体
BR112015029953A2 (pt) 2013-06-14 2017-09-26 Bayer Pharma AG anticorpos anti-tweakr e seus usos
US9238034B2 (en) * 2013-07-09 2016-01-19 The Translational Genomics Research Institute FN14 antagonists and therapeutic uses thereof
MY204672A (en) * 2018-10-31 2024-09-09 Astellas Pharma Inc Anti-human fn14 antibody

Also Published As

Publication number Publication date
AU2019369771B2 (en) 2025-12-18
TW202035459A (zh) 2020-10-01
EP3875114A1 (de) 2021-09-08
IL282650B1 (en) 2024-05-01
JP7415939B2 (ja) 2024-01-17
ZA202102879B (en) 2022-10-26
CA3117930A1 (en) 2020-05-07
MY204672A (en) 2024-09-09
PH12021550945A1 (en) 2022-03-28
CO2021005768A2 (es) 2021-05-10
US12209134B2 (en) 2025-01-28
CN112930195B (zh) 2024-03-19
JOP20210093A1 (ar) 2023-01-30
KR102922399B1 (ko) 2026-02-04
KR20210084473A (ko) 2021-07-07
AR123671A1 (es) 2023-01-04
BR112021008424A2 (pt) 2021-09-28
EP3875114A4 (de) 2022-08-10
WO2020090892A1 (ja) 2020-05-07
TWI843763B (zh) 2024-06-01
MA54097A (fr) 2022-02-09
JOP20210093B1 (ar) 2024-12-22
IL282650B2 (en) 2024-09-01
JOP20210092A1 (ar) 2021-04-29
CN112930195A (zh) 2021-06-08
MX2021004976A (es) 2021-06-15
AU2019369771A1 (en) 2021-06-03
JPWO2020090892A1 (ja) 2021-09-24
IL282650A (en) 2021-06-30
US20210388096A1 (en) 2021-12-16

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