SG11202104792SA - Ketamine pamoate and use thereof - Google Patents

Ketamine pamoate and use thereof

Info

Publication number
SG11202104792SA
SG11202104792SA SG11202104792SA SG11202104792SA SG11202104792SA SG 11202104792S A SG11202104792S A SG 11202104792SA SG 11202104792S A SG11202104792S A SG 11202104792SA SG 11202104792S A SG11202104792S A SG 11202104792SA SG 11202104792S A SG11202104792S A SG 11202104792SA
Authority
SG
Singapore
Prior art keywords
ketamine pamoate
pamoate
ketamine
Prior art date
Application number
SG11202104792SA
Inventor
Tong-Ho Lin
Yung-Shun Wen
Chia-Hsien Chen
Wei-Ju Chang
Original Assignee
Alar Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alar Pharmaceuticals Inc filed Critical Alar Pharmaceuticals Inc
Publication of SG11202104792SA publication Critical patent/SG11202104792SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/34Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
    • C07C211/35Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing only non-condensed rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/105Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic
    • C07C65/11Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic with carboxyl groups on a condensed ring system containing two rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG11202104792SA 2019-01-11 2020-01-10 Ketamine pamoate and use thereof SG11202104792SA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962791058P 2019-01-11 2019-01-11
US201962871763P 2019-07-09 2019-07-09
PCT/CN2020/071404 WO2020143762A1 (en) 2019-01-11 2020-01-10 Ketamine pamoate and use thereof

Publications (1)

Publication Number Publication Date
SG11202104792SA true SG11202104792SA (en) 2021-06-29

Family

ID=71521952

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104792SA SG11202104792SA (en) 2019-01-11 2020-01-10 Ketamine pamoate and use thereof

Country Status (27)

Country Link
US (1) US11981617B2 (en)
EP (1) EP3908570B1 (en)
JP (1) JP7451538B2 (en)
KR (1) KR102892857B1 (en)
CN (1) CN113423686B (en)
AU (1) AU2020206826B2 (en)
CL (1) CL2021001803A1 (en)
CO (1) CO2021006884A2 (en)
DK (1) DK3908570T3 (en)
ES (1) ES2974259T3 (en)
FI (1) FI3908570T3 (en)
HR (1) HRP20240255T1 (en)
HU (1) HUE065684T2 (en)
LT (1) LT3908570T (en)
MX (1) MX2021006029A (en)
MY (1) MY203905A (en)
PE (1) PE20211550A1 (en)
PH (1) PH12021551157A1 (en)
PL (1) PL3908570T3 (en)
PT (1) PT3908570T (en)
RS (1) RS65271B1 (en)
SG (1) SG11202104792SA (en)
SI (1) SI3908570T1 (en)
SM (1) SMT202400100T1 (en)
TW (1) TWI827783B (en)
WO (1) WO2020143762A1 (en)
ZA (1) ZA202103132B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE056378T2 (en) 2013-09-13 2022-02-28 Univ Chiba Nat Univ Corp Application of r-ketamine and salt thereof as pharmaceuticals
ES2907692T3 (en) 2017-12-29 2022-04-26 Celon Pharma Sa Composition of dry powder ketamine for pulmonary administration in treatment-resistant depression
US11980595B2 (en) 2018-02-15 2024-05-14 National University Corporation Chiba University Preventive or therapeutic agent and pharmaceutical composition for inflammatory diseases or bone diseases
WO2019213551A1 (en) 2018-05-04 2019-11-07 Perception Neuroscience, Inc. Methods of treating substance abuse
PH12022550775A1 (en) * 2019-12-20 2023-08-23 Alar Pharmaceuticals Inc Long-acting injectable formulations of ketamine pamoate salts
US20210322669A1 (en) * 2020-04-16 2021-10-21 Invictus Health, Inc. Method for treatment of traumatic brain injuries
CN112263572A (en) * 2020-11-17 2021-01-26 厦门大学附属翔安医院 Application of dextroketamine in preparing medicine for treating demyelinating diseases

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1248869A2 (en) 2000-01-07 2002-10-16 Transform Pharmaceuticals, Inc. High-throughput formation, identification, and analysis of diverse solid-forms
US20080293695A1 (en) 2007-05-22 2008-11-27 David William Bristol Salts of physiologically active and psychoactive alkaloids and amines simultaneously exhibiting bioavailability and abuse resistance
US9421266B2 (en) * 2007-05-22 2016-08-23 Pisgah Laboratories, Inc. Safety of pseudoephedrine drug products
JO2857B1 (en) 2008-06-16 2015-03-15 سانوفي أفينتس Phenyl-alkylpiperazines with tnf-modulating activity
JO3227B1 (en) 2011-09-08 2018-03-08 Otsuka Pharma Co Ltd Piperazine-substituted benzothiophene deriveatives as antipsychotic agents
JP2014196292A (en) 2013-03-07 2014-10-16 大塚製薬株式会社 Medicine
CN106562952B (en) * 2015-10-09 2020-06-09 江阴安博生物医药有限公司 Use of ketamine in the treatment of major depressive disorder
WO2017167180A1 (en) 2016-03-29 2017-10-05 上海华汇拓医药科技有限公司 Vortioxetine pamoic acid salt and crystal form thereof
EP3558279A4 (en) * 2016-12-26 2020-12-02 Cellix Bio Private Limited COMPOSITIONS AND PROCEDURES FOR TREATMENT OF CHRONIC PAIN
PL3737665T3 (en) * 2018-01-10 2026-04-20 XWPharma Ltd. Prodrugs of ketamine, compositions and uses thereof

Also Published As

Publication number Publication date
MX2021006029A (en) 2021-09-23
DK3908570T3 (en) 2024-02-26
AU2020206826A1 (en) 2021-06-03
CN113423686A (en) 2021-09-21
CN113423686B (en) 2023-08-22
BR112021013340A2 (en) 2021-09-14
HRP20240255T1 (en) 2024-05-24
PT3908570T (en) 2024-03-15
CO2021006884A2 (en) 2021-06-10
EP3908570B1 (en) 2023-12-13
ZA202103132B (en) 2024-11-27
FI3908570T3 (en) 2024-02-13
MY203905A (en) 2024-07-24
JP7451538B2 (en) 2024-03-18
KR20210116517A (en) 2021-09-27
NZ775810A (en) 2024-07-26
PH12021551157A1 (en) 2021-11-03
LT3908570T (en) 2024-03-12
ES2974259T3 (en) 2024-06-26
HUE065684T2 (en) 2024-06-28
TW202042796A (en) 2020-12-01
SI3908570T1 (en) 2024-04-30
CA3118954A1 (en) 2020-07-16
CL2021001803A1 (en) 2021-12-24
EP3908570A4 (en) 2022-10-19
EP3908570A1 (en) 2021-11-17
RS65271B1 (en) 2024-03-29
KR102892857B1 (en) 2025-11-27
SMT202400100T1 (en) 2024-05-14
US20220119338A1 (en) 2022-04-21
JP2022518003A (en) 2022-03-11
TWI827783B (en) 2024-01-01
PE20211550A1 (en) 2021-08-16
AU2020206826B2 (en) 2024-05-02
US11981617B2 (en) 2024-05-14
WO2020143762A1 (en) 2020-07-16
PL3908570T3 (en) 2024-07-01

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