SG131694G - Novel vitamin D analogues - Google Patents

Novel vitamin D analogues

Info

Publication number: SG131694G
Authority: SG; Singapore
Prior art keywords: formula; compounds; groups; diseases; present
Prior art date: 1989-02-23

Application number

SG131694A

Other languages

English (en)

Inventor

Martin John Calverley

Kai Hansen

Lise Binderup

Original Assignee

Leo Pharm Prod Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-23

Filing date

1994-09-12

Publication date

1995-01-13

1989-02-23 Priority to GB898904153A priority Critical patent/GB8904153D0/en

1990-02-06 Priority to IE42090A priority patent/IE63309B1/en

1990-02-13 Priority to PCT/DK1990/000037 priority patent/WO1990009992A1/fr

1990-02-13 Priority to AT9090903795T priority patent/ATE104958T1/de

1990-02-13 Priority to EP90903795A priority patent/EP0460034B1/fr

1990-02-13 Priority to DK90903795.4T priority patent/DK0460034T3/da

1990-02-13 Priority to CA002053231A priority patent/CA2053231C/fr

1990-02-13 Priority to ES90903795T priority patent/ES2055906T3/es

1990-02-13 Priority to AU51984/90A priority patent/AU627002B2/en

1990-02-13 Priority to DE69008518T priority patent/DE69008518T2/de

1990-02-13 Priority to JP2504127A priority patent/JP2807084B2/ja

1990-02-22 Priority to PT93239A priority patent/PT93239B/pt

1994-09-12 Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd

1994-09-12 Priority to SG131694A priority patent/SG131694G/en

1994-11-17 Priority to HK128994A priority patent/HK128994A/en

1995-01-13 Publication of SG131694G publication Critical patent/SG131694G/en

Links

229930003316 Vitamin D Natural products 0.000 title 1
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title 1
235000019166 vitamin D Nutrition 0.000 title 1
239000011710 vitamin D Substances 0.000 title 1
150000003710 vitamin D derivatives Chemical class 0.000 title 1
229940046008 vitamin d Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
208000023275 Autoimmune disease Diseases 0.000 abstract 1
206010020772 Hypertension Diseases 0.000 abstract 1
229910019142 PO4 Inorganic materials 0.000 abstract 1
230000002159 abnormal effect Effects 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
208000006673 asthma Diseases 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
230000024245 cell differentiation Effects 0.000 abstract 1
230000004663 cell proliferation Effects 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
210000000987 immune system Anatomy 0.000 abstract 1
238000001727 in vivo Methods 0.000 abstract 1
208000027866 inflammatory disease Diseases 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000010452 phosphate Substances 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Oncology (AREA)
Rheumatology (AREA)
Emergency Medicine (AREA)
Communicable Diseases (AREA)
Hematology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Pulmonology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrane Compounds (AREA)

SG131694A 1989-02-23 1994-09-12 Novel vitamin D analogues SG131694G (en)

Priority Applications (14)

Application Number	Priority Date	Filing Date	Title
GB898904153A GB8904153D0 (en)	1989-02-23	1989-02-23	Chemical compounds
IE42090A IE63309B1 (en)	1989-02-23	1990-02-06	Novel vitamin d analogues
DE69008518T DE69008518T2 (de)	1989-02-23	1990-02-13	Vitamin d analoge.
EP90903795A EP0460034B1 (fr)	1989-02-23	1990-02-13	Nouveaux analogues de vitamine d
DK90903795.4T DK0460034T3 (da)	1989-02-23	1990-02-13	Nye D-vitaminanaloger
CA002053231A CA2053231C (fr)	1989-02-23	1990-02-13	Analogues de la vitamine d
ES90903795T ES2055906T3 (es)	1989-02-23	1990-02-13	Nuevos analogos de vitamina d.
PCT/DK1990/000037 WO1990009992A1 (fr)	1989-02-23	1990-02-13	Nouveaux analogues de vitamine d
AT9090903795T ATE104958T1 (de)	1989-02-23	1990-02-13	Vitamin d analoge.
JP2504127A JP2807084B2 (ja)	1989-02-23	1990-02-13	新規ビタミンｄ類似体
AU51984/90A AU627002B2 (en)	1989-02-23	1990-02-13	Novel vitamin d analogues
PT93239A PT93239B (pt)	1989-02-23	1990-02-22	Processo para a preparacao de novos analogos da vitamina "d" e de composicoes farmaceuticas que os contem
SG131694A SG131694G (en)	1989-02-23	1994-09-12	Novel vitamin D analogues
HK128994A HK128994A (en)	1989-02-23	1994-11-17	Novel vitamin d analogues

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB898904153A GB8904153D0 (en)	1989-02-23	1989-02-23	Chemical compounds
SG131694A SG131694G (en)	1989-02-23	1994-09-12	Novel vitamin D analogues

Publications (1)

Publication Number	Publication Date
SG131694G true SG131694G (en)	1995-01-13

Family

ID=26295001

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG131694A SG131694G (en)	1989-02-23	1994-09-12	Novel vitamin D analogues

Country Status (14)

Country	Link
EP (1)	EP0460034B1 (fr)
JP (1)	JP2807084B2 (fr)
AT (1)	ATE104958T1 (fr)
AU (1)	AU627002B2 (fr)
CA (1)	CA2053231C (fr)
DE (1)	DE69008518T2 (fr)
DK (1)	DK0460034T3 (fr)
ES (1)	ES2055906T3 (fr)
GB (1)	GB8904153D0 (fr)
HK (1)	HK128994A (fr)
IE (1)	IE63309B1 (fr)
PT (1)	PT93239B (fr)
SG (1)	SG131694G (fr)
WO (1)	WO1990009992A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8904154D0 (en) *	1989-02-23	1989-04-05	Leo Pharm Prod Ltd	Chemical compounds
GB9015774D0 (en) *	1990-07-18	1990-09-05	Leo Pharm Prod Ltd	Novel treatment
DE4101953A1 (de) *	1991-01-19	1992-07-23	Schering Ag	23-oxa-derivate in der vitamin-d-reihe, verfahren zu ihrer herstellung diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel
US5182396A (en) *	1991-03-29	1993-01-26	Nisshin Flour Milling Co., Ltd.	1-hydroxyvitamin d derivatives
AU650751B2 (en) *	1991-05-28	1994-06-30	Wisconsin Alumni Research Foundation	Novel synthesis of 19-nor vitamin D compounds
US5225569A (en) *	1991-08-09	1993-07-06	Hoffmann-La Roche Inc.	Process for precursors to calcitriol and related compounds
DE69230274T2 (de) *	1991-08-09	2000-05-31	F. Hoffmann-La Roche Ag, Basel	Verfahren zur Herstellung von Zwischenverbindungen für Vitamin-D-Derivate sowie Verbindungen
PT665221E (pt) *	1992-10-16	2000-06-30	Chugai Pharmaceutical Co Ltd	Derivado da vitamina d e processo para a sua producao
GB9226877D0 (en) *	1992-12-23	1993-02-17	Leo Pharm Prod Ltd	Chemical compounds
EP1034178A1 (fr) *	1997-11-24	2000-09-13	Clarion Pharmaceuticals, Inc.	Conjugues phosphoethanolamines de composes de vitamine d
EP1042335A1 (fr)	1997-12-17	2000-10-11	Schering Aktiengesellschaft	Derives de vitamine d avec des atomes de phosphore dans les chaines laterales
EP0927721A1 (fr) *	1997-12-17	1999-07-07	Schering Aktiengesellschaft	Nouveaux dérivés de la vitamine D ayant des atomes de phosphore sur les chaines latérales, intermédiaires pour leur préparation et leur utilisation pour la préparation de médicaments
JP5563324B2 (ja) *	2010-02-03	2014-07-30	フォーモサ・ラボラトリーズ・インコーポレーテッド	マキサカルシトール中間体およびその製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1332841C (fr) *	1984-11-27	1994-11-01	Noboru Kubodera	Derives de vitamine d et procede de production
GB8904154D0 (en) *	1989-02-23	1989-04-05	Leo Pharm Prod Ltd	Chemical compounds

1989
- 1989-02-23 GB GB898904153A patent/GB8904153D0/en active Pending
1990
- 1990-02-06 IE IE42090A patent/IE63309B1/en not_active IP Right Cessation
- 1990-02-13 JP JP2504127A patent/JP2807084B2/ja not_active Expired - Fee Related
- 1990-02-13 DE DE69008518T patent/DE69008518T2/de not_active Expired - Fee Related
- 1990-02-13 AU AU51984/90A patent/AU627002B2/en not_active Ceased
- 1990-02-13 WO PCT/DK1990/000037 patent/WO1990009992A1/fr not_active Ceased
- 1990-02-13 DK DK90903795.4T patent/DK0460034T3/da active
- 1990-02-13 EP EP90903795A patent/EP0460034B1/fr not_active Expired - Lifetime
- 1990-02-13 AT AT9090903795T patent/ATE104958T1/de not_active IP Right Cessation
- 1990-02-13 CA CA002053231A patent/CA2053231C/fr not_active Expired - Fee Related
- 1990-02-13 ES ES90903795T patent/ES2055906T3/es not_active Expired - Lifetime
- 1990-02-22 PT PT93239A patent/PT93239B/pt not_active IP Right Cessation
1994
- 1994-09-12 SG SG131694A patent/SG131694G/en unknown
- 1994-11-17 HK HK128994A patent/HK128994A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK0460034T3 (da)	1994-05-30
HK128994A (en)	1994-11-25
EP0460034B1 (fr)	1994-04-27
AU5198490A (en)	1990-09-26
EP0460034A1 (fr)	1991-12-11
CA2053231A1 (fr)	1990-08-24
IE900420L (en)	1990-08-23
PT93239A (pt)	1990-08-31
ATE104958T1 (de)	1994-05-15
AU627002B2 (en)	1992-08-13
WO1990009992A1 (fr)	1990-09-07
IE63309B1 (en)	1995-04-05
GB8904153D0 (en)	1989-04-05
DE69008518T2 (de)	1994-08-18
PT93239B (pt)	1996-01-31
CA2053231C (fr)	2000-01-25
JPH04504573A (ja)	1992-08-13
ES2055906T3 (es)	1994-09-01
JP2807084B2 (ja)	1998-09-30
DE69008518D1 (de)	1994-06-01

Publication	Publication Date	Title
HUT59664A (en)	1992-06-29	Novel vitamin d analogues
PH27301A (en)	1993-05-04	Novel vitamin d analogues
CA2078555A1 (fr)	1992-02-16	Nouveaux analogues de la vitamine d
IE900420L (en)	1990-08-23	Novel vitamin d analogues
NZ234216A (en)	1993-03-26	Vitamin d analogues, preparation and pharmaceutical compositions thereof
HU9401515D0 (en)	1994-08-29	New polypeptide compound and a process for prepation thereof
HUT62594A (en)	1993-05-28	Process for producing sulfated glycosaminoglycanoid derivatives and pharmaceutical compositions comprising such compounds
AU1404988A (en)	1988-10-06	New amino-5,6,7,8-tetrahydronaphto(2,3-b)furan derivatives, the processes for preparing them and the pharmaceutical compositions which contain them
EP0662953A1 (fr)	1995-07-19	Nouveaux analogues de vitamine d.
AU6016590A (en)	1991-02-07	New oxazolopyridine derivatives, process for preparing them and pharmaceutical compositions containing them
EP0382618A3 (fr)	1991-11-13	Dérivés aminoalkoxyphényle, leur procédé de préparation ainsi que les compositions en contenant
IN161663B (fr)	1988-01-09