SG170022A1 - Method for production of peptide thioester compound - Google Patents
Method for production of peptide thioester compoundInfo
- Publication number
- SG170022A1 SG170022A1 SG201101270-5A SG2011012705A SG170022A1 SG 170022 A1 SG170022 A1 SG 170022A1 SG 2011012705 A SG2011012705 A SG 2011012705A SG 170022 A1 SG170022 A1 SG 170022A1
- Authority
- SG
- Singapore
- Prior art keywords
- peptide
- acid
- production
- thioester compound
- solid phase
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- -1 thioester compound Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000007790 solid phase Substances 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- 238000010532 solid phase synthesis reaction Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006092569 | 2006-03-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG170022A1 true SG170022A1 (en) | 2011-04-29 |
Family
ID=38563716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG201101270-5A SG170022A1 (en) | 2006-03-29 | 2007-03-28 | Method for production of peptide thioester compound |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8058394B2 (da) |
| EP (1) | EP2000474B1 (da) |
| JP (1) | JP5328345B2 (da) |
| KR (1) | KR101462454B1 (da) |
| CN (1) | CN101437836B (da) |
| AU (1) | AU2007232742B2 (da) |
| CA (1) | CA2647867C (da) |
| DK (1) | DK2000474T3 (da) |
| SG (1) | SG170022A1 (da) |
| TW (2) | TW200806686A (da) |
| WO (1) | WO2007114454A1 (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8642725B2 (en) | 2009-06-26 | 2014-02-04 | Glytech Inc. | Process for production of peptide thioester |
| US20140377807A1 (en) | 2011-09-26 | 2014-12-25 | Glytech, Inc. | Method for producing polypeptide fragment with high efficiency, which is suitable for ncl method |
| JP6219308B2 (ja) * | 2012-11-30 | 2017-10-25 | 株式会社糖鎖工学研究所 | 糖鎖付加リンカー、糖鎖付加リンカーと生理活性物質とを含む化合物またはその塩、及びそれらの製造方法 |
| HUE034308T2 (en) | 2013-03-21 | 2018-02-28 | Sanofi Aventis Deutschland | Preparation of hydantoin-containing peptide products |
| CN105102427B (zh) | 2013-03-21 | 2018-09-07 | 赛诺菲-安万特德国有限公司 | 含有环状酰亚胺的肽产物的合成 |
| CN106928313B (zh) * | 2015-12-31 | 2020-12-11 | 深圳翰宇药业股份有限公司 | 一种c-端修饰肽的合成方法 |
| US10669306B2 (en) | 2016-02-04 | 2020-06-02 | University Of Washington | Solid supports for use in solid-phase peptide synthesis, kits, and related methods |
| JP7067798B2 (ja) * | 2017-03-02 | 2022-05-16 | 株式会社糖鎖工学研究所 | アミノ酸ポリマーの製造方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ295838B6 (cs) * | 1996-09-09 | 2005-11-16 | Zealand Pharma A/S | Způsob výroby peptidů |
| EP2481746A1 (en) | 2001-06-19 | 2012-08-01 | Otsuka Chemical Co., Ltd. | Process for producing sugar chain asparagine derivative |
| DE10216513A1 (de) * | 2002-04-10 | 2003-10-23 | Joerg Rademann | Polymerverbindung aufgebaut aus linearen Polymerketten |
| US7943763B2 (en) | 2002-07-05 | 2011-05-17 | Otsuka Chemical Holdings Co., Ltd. | Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides |
| JPWO2005095331A1 (ja) | 2004-03-31 | 2008-02-21 | 塩野義製薬株式会社 | 糖鎖−ペプチド結合剤 |
| CN1254484C (zh) * | 2004-04-30 | 2006-05-03 | 吉林省一心制药有限公司 | 醋酸奥曲肽的固相合成方法 |
| US20100016547A1 (en) | 2005-11-30 | 2010-01-21 | Takaomi Ito | Glycosilated Peptide and Medicine Comprising It as an Effective Ingredient |
-
2007
- 2007-03-28 DK DK07740944.9T patent/DK2000474T3/da active
- 2007-03-28 US US12/295,113 patent/US8058394B2/en active Active
- 2007-03-28 SG SG201101270-5A patent/SG170022A1/en unknown
- 2007-03-28 CA CA2647867A patent/CA2647867C/en active Active
- 2007-03-28 EP EP07740944.9A patent/EP2000474B1/en active Active
- 2007-03-28 AU AU2007232742A patent/AU2007232742B2/en not_active Ceased
- 2007-03-28 CN CN2007800158333A patent/CN101437836B/zh active Active
- 2007-03-28 JP JP2008508707A patent/JP5328345B2/ja active Active
- 2007-03-28 KR KR1020087025264A patent/KR101462454B1/ko active Active
- 2007-03-28 WO PCT/JP2007/057508 patent/WO2007114454A1/ja not_active Ceased
- 2007-03-29 TW TW096110938A patent/TW200806686A/zh unknown
- 2007-03-29 TW TW099136653A patent/TWI450905B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007232742A1 (en) | 2007-10-11 |
| KR101462454B1 (ko) | 2014-11-17 |
| CN101437836B (zh) | 2013-07-24 |
| JP5328345B2 (ja) | 2013-10-30 |
| CN101437836A (zh) | 2009-05-20 |
| US20090137780A1 (en) | 2009-05-28 |
| TW201109347A (en) | 2011-03-16 |
| TW200806686A (en) | 2008-02-01 |
| WO2007114454A1 (ja) | 2007-10-11 |
| AU2007232742B2 (en) | 2012-02-02 |
| CA2647867A1 (en) | 2007-10-11 |
| KR20090007709A (ko) | 2009-01-20 |
| DK2000474T3 (da) | 2018-01-22 |
| TWI450905B (zh) | 2014-09-01 |
| EP2000474A4 (en) | 2012-05-09 |
| CA2647867C (en) | 2015-11-03 |
| EP2000474B1 (en) | 2017-11-01 |
| EP2000474A1 (en) | 2008-12-10 |
| TWI353989B (da) | 2011-12-11 |
| JPWO2007114454A1 (ja) | 2009-08-20 |
| US8058394B2 (en) | 2011-11-15 |
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