SG43237A1 - Cloning of the biosynthetic pathway for chlortetracycline and tetracyline formation form streptomyces aureofaciens and its exptession in steptomyces lividans - Google Patents

Cloning of the biosynthetic pathway for chlortetracycline and tetracyline formation form streptomyces aureofaciens and its exptession in steptomyces lividans

Info

Publication number: SG43237A1
Authority: SG; Singapore
Prior art keywords: exptession; tetracyline; chlortetracycline; cloning; biosynthetic pathway
Prior art date: 1990-07-26

Application number

SG1996006004A

Other languages

English (en)

Inventor

Nancy Strathy

Michael J Ryan

Kason A Lotvin

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-07-26

Filing date

1991-07-27

Publication date

1997-10-17

1991-07-27 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1997-10-17 Publication of SG43237A1 publication Critical patent/SG43237A1/en

Links

239000004099 Chlortetracycline Substances 0.000 title 1
241000186984 Kitasatospora aureofaciens Species 0.000 title 1
230000006696 biosynthetic metabolic pathway Effects 0.000 title 1
230000015572 biosynthetic process Effects 0.000 title 1
CYDMQBQPVICBEU-UHFFFAOYSA-N chlorotetracycline Natural products C1=CC(Cl)=C2C(O)(C)C3CC4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-UHFFFAOYSA-N 0.000 title 1
CYDMQBQPVICBEU-XRNKAMNCSA-N chlortetracycline Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-XRNKAMNCSA-N 0.000 title 1
229960004475 chlortetracycline Drugs 0.000 title 1
235000019365 chlortetracycline Nutrition 0.000 title 1
238000010367 cloning Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P29/00—Preparation of compounds containing a naphthacene ring system, e.g. tetracycline

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Analytical Chemistry (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

SG1996006004A 1990-07-26 1991-07-27 Cloning of the biosynthetic pathway for chlortetracycline and tetracyline formation form streptomyces aureofaciens and its exptession in steptomyces lividans SG43237A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US55803990A	1990-07-26	1990-07-26

Publications (1)

Publication Number	Publication Date
SG43237A1 true SG43237A1 (en)	1997-10-17

Family

ID=24227935

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG1996006004A SG43237A1 (en)	1990-07-26	1991-07-27	Cloning of the biosynthetic pathway for chlortetracycline and tetracyline formation form streptomyces aureofaciens and its exptession in steptomyces lividans

Country Status (13)

Country	Link
EP (1)	EP0468220A3 (fr)
JP (1)	JPH04346786A (fr)
KR (1)	KR920002776A (fr)
AU (1)	AU652766B2 (fr)
CA (1)	CA2047833C (fr)
HU (1)	HUT60771A (fr)
IE (1)	IE912623A1 (fr)
IL (1)	IL98684A0 (fr)
NZ (1)	NZ239042A (fr)
PT (1)	PT98428B (fr)
SG (1)	SG43237A1 (fr)
TW (1)	TW218893B (fr)
ZA (1)	ZA915863B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0468217B1 (fr) *	1990-07-26	1998-05-20	American Cyanamid Company	Cosmide bifonctionnel utile pour le clonage d'ADN d'actinomycete
US5639949A (en) *	1990-08-20	1997-06-17	Ciba-Geigy Corporation	Genes for the synthesis of antipathogenic substances
US5662898A (en) *	1990-08-20	1997-09-02	Ciba-Geigy Corporation	Genes for the synthesis of antipathogenic substances
TW318189B (fr) *	1991-12-06	1997-10-21	American Cyanamid Co
US6524812B1 (en)	1993-10-07	2003-02-25	Regents Of The University Of Minnesota	Genes encoding resistance to DNA alkylating agents
US6495348B1 (en)	1993-10-07	2002-12-17	Regents Of The University Of Minnesota	Mitomycin biosynthetic gene cluster
US6117670A (en) *	1994-06-08	2000-09-12	Novartis Finance Corporation	Pyrrolnitrin biosynthesis genes and uses thereof
US5989903A (en) *	1995-06-07	1999-11-23	American Cyanamid Company	Strain for the production of 6-dimethyltetracycline, method for producing the strain and vector for use in the method
US6600029B1 (en)	1995-12-19	2003-07-29	Regents Of The University Of Minnesota	Metabolic engineering of polyhydroxyalkanoate monomer synthases
US6261842B1 (en) *	1997-10-23	2001-07-17	Wisconsin Alumni Research Foundation	Microorganism genomics, compositions and methods related thereto
WO1999067374A1 (fr) *	1998-06-23	1999-12-29	Biosearch Italia S.P.A.	Procedes de transfert de la capacite de production d'un produit naturel dans un hote de production approprie
CN110129244B (zh) *	2019-01-23	2023-09-15	河北圣雪大成制药有限责任公司	链霉菌底盘菌株及其构建方法、在异源表达研究中的应用
CN109699495B (zh) *	2019-02-12	2022-04-08	云南农业大学	一种提高金毛狗脊孢子萌发率的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5098837A (en) *	1988-06-07	1992-03-24	Eli Lilly And Company	Macrolide biosynthetic genes for use in streptomyces and other organisms
EP0468217B1 (fr) *	1990-07-26	1998-05-20	American Cyanamid Company	Cosmide bifonctionnel utile pour le clonage d'ADN d'actinomycete

1991
- 1991-06-27 EP EP19910110631 patent/EP0468220A3/en not_active Withdrawn
- 1991-06-29 TW TW080105067A patent/TW218893B/zh active
- 1991-07-01 IL IL98684A patent/IL98684A0/xx unknown
- 1991-07-19 NZ NZ239042A patent/NZ239042A/xx unknown
- 1991-07-24 PT PT98428A patent/PT98428B/pt not_active IP Right Cessation
- 1991-07-24 CA CA002047833A patent/CA2047833C/fr not_active Expired - Fee Related
- 1991-07-24 JP JP3206176A patent/JPH04346786A/ja active Pending
- 1991-07-25 IE IE262391A patent/IE912623A1/en unknown
- 1991-07-25 ZA ZA915863A patent/ZA915863B/xx unknown
- 1991-07-25 AU AU81340/91A patent/AU652766B2/en not_active Ceased
- 1991-07-25 HU HU912500A patent/HUT60771A/hu unknown
- 1991-07-26 KR KR1019910013058A patent/KR920002776A/ko not_active Withdrawn
- 1991-07-27 SG SG1996006004A patent/SG43237A1/en unknown

Also Published As

Publication number	Publication date
HUT60771A (en)	1992-10-28
CA2047833A1 (fr)	1992-01-27
IL98684A0 (en)	1992-07-15
EP0468220A3 (en)	1992-09-23
PT98428A (pt)	1992-06-30
EP0468220A2 (fr)	1992-01-29
TW218893B (fr)	1994-01-11
ZA915863B (en)	1992-04-29
KR920002776A (ko)	1992-02-28
NZ239042A (en)	1993-09-27
CA2047833C (fr)	2002-12-17
HU912500D0 (en)	1991-12-30
JPH04346786A (ja)	1992-12-02
AU652766B2 (en)	1994-09-08
PT98428B (pt)	1999-01-29
IE912623A1 (en)	1992-01-29
AU8134091A (en)	1992-01-30

Publication	Publication Date	Title
SG43237A1 (en)	1997-10-17	Cloning of the biosynthetic pathway for chlortetracycline and tetracyline formation form streptomyces aureofaciens and its exptession in steptomyces lividans
AU3222995A (en)	1996-03-04	Education and entertainment device with dynamic configuration and operation
GB9303548D0 (en)	1993-04-07	Machines for amusement and playing games
AU3989389A (en)	1990-02-05	Audio quiz game
AU588489B2 (en)	1989-09-14	Web dividing and rewinding machine
GB9313456D0 (en)	1993-08-11	Machines for amusement and playing games
AU1858592A (en)	1993-05-20	Oscillating damper and air-swept distributor
ZA9710740B (en)	1998-11-30	Production of paper and paper board
GR3023964T3 (en)	1997-09-30	Cube making and peeling machine
GB2219745B (en)	1992-12-02	Games and random selection apparatus therefore
EP0489930A4 (en)	1992-12-09	Papermaking process and papermaking additive
GB8926332D0 (en)	1990-01-10	Surface tension feeder
GB2313829B (en)	2000-02-16	Carton with product retention
AU2210395A (en)	1995-10-30	Form 1 ranitidine hydrochloride with increased density
AU1850292A (en)	1993-01-07	Game and game apparatus
ZA911036B (en)	1992-10-28	Fatty acid-specific lipase
TW298861U (en)	1997-02-21	Dynamic floating plate toy
SG44888A1 (en)	1997-12-19	Fortified hydrocarbon and process for making and using the same
GB8827962D0 (en)	1989-01-05	Game promotional material
GB9607255D0 (en)	1996-06-12	Seeds with increased lipid content and production thereof
GB9219350D0 (en)	1992-10-28	Playing surface
GB9109134D0 (en)	1991-06-12	Music quiz
GB9016218D0 (en)	1990-09-05	Method of improving the surface characteristics of paper and paper board
HUT76372A (en)	1997-08-28	Feed additive and premix
SU1592648A1 (ru)	1990-09-15	Пылeугoльhoe гopeлoчhoe уctpoйctbo