SG60203A1 - Steroid compounds having contraceptive and anti-osteoporosis activity - Google Patents

Steroid compounds having contraceptive and anti-osteoporosis activity

Info

Publication number
SG60203A1
SG60203A1 SG1998000359A SG1998000359A SG60203A1 SG 60203 A1 SG60203 A1 SG 60203A1 SG 1998000359 A SG1998000359 A SG 1998000359A SG 1998000359 A SG1998000359 A SG 1998000359A SG 60203 A1 SG60203 A1 SG 60203A1
Authority
SG
Singapore
Prior art keywords
contraceptive
steroid compounds
osteoporosis activity
osteoporosis
activity
Prior art date
Application number
SG1998000359A
Other languages
English (en)
Inventor
Hubert Jan Jozef Loozen
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of SG60203A1 publication Critical patent/SG60203A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0085—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG1998000359A 1997-02-21 1998-02-19 Steroid compounds having contraceptive and anti-osteoporosis activity SG60203A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97102884 1997-02-21

Publications (1)

Publication Number Publication Date
SG60203A1 true SG60203A1 (en) 1999-02-22

Family

ID=8226513

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1998000359A SG60203A1 (en) 1997-02-21 1998-02-19 Steroid compounds having contraceptive and anti-osteoporosis activity

Country Status (26)

Country Link
US (2) US6077873A (id)
EP (1) EP0869132B1 (id)
JP (1) JP4392066B2 (id)
KR (1) KR19980071540A (id)
CN (2) CN100522984C (id)
AR (1) AR011680A1 (id)
AT (1) ATE205217T1 (id)
AU (1) AU723713B2 (id)
BR (1) BR9800718B1 (id)
CA (1) CA2229960C (id)
CZ (1) CZ50598A3 (id)
DE (1) DE69801539T2 (id)
DK (1) DK0869132T3 (id)
ES (1) ES2164400T3 (id)
HU (1) HU223755B1 (id)
ID (1) ID19947A (id)
IL (1) IL123195A (id)
NO (1) NO310724B1 (id)
NZ (1) NZ329789A (id)
PL (1) PL188079B1 (id)
PT (1) PT869132E (id)
RU (1) RU2182153C2 (id)
SG (1) SG60203A1 (id)
TR (1) TR199800282A1 (id)
TW (1) TW403736B (id)
ZA (1) ZA981344B (id)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL123195A (en) * 1997-02-21 2002-11-10 Akzo Nobel Nv Steroid compounds with anti-pregnancy activity and against bone thinning, preparation and pharmaceutical preparations containing them
US6667299B1 (en) * 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
US6756366B1 (en) * 1999-04-06 2004-06-29 Akzo Nobel N.V. Orally active androgens
CO5271709A1 (es) 2000-01-12 2003-04-30 Pfizer Prod Inc Composiciones y procedimientos para el y tratamiento de afecciones que responden a estrogenos
TWI225068B (en) * 2000-06-06 2004-12-11 Akzo Nobel Nv Anellated steroid compounds having contraceptive and anti-osteoporosis activity
JP2002241395A (ja) * 2001-02-16 2002-08-28 Taiho Yakuhin Kogyo Kk エストラ−４，６−ジエン−３，１７−ジオンの製造方法
US7250289B2 (en) 2002-11-20 2007-07-31 Affymetrix, Inc. Methods of genetic analysis of mouse
UA89964C2 (ru) 2004-09-08 2010-03-25 Н.В. Органон 15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ
JP2010513475A (ja) * 2006-12-20 2010-04-30 ランドシュタイナー サイエンティフィック エッセ アー デ シー ヴイ リセドロネートおよびビタミンｄ組成物
TW201109346A (en) * 2009-06-10 2011-03-16 Organon Nv Substituted 16,17-annellated steroid compounds for use in women's healthcare
US8367648B2 (en) 2009-06-10 2013-02-05 Msd Oss B.V. Substituted 16,17-annellated steroid compounds for use in womens healthcare
WO2023000135A1 (en) * 2021-07-19 2023-01-26 Context Biopharma Inc. Processes of making onapristone and intermediates thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59010853D1 (de) * 1989-08-04 1998-12-03 Schering Ag 11 Beta-Aryl-gona-4,9-dien-3-one
JP3135564B2 (ja) * 1989-08-04 2001-02-19 シエーリング アクチエンゲゼルシヤフト １１β―置換１６α，１７α―メチレン―エストラ―４，９―ジエン―３―オン
US5407928A (en) * 1990-08-15 1995-04-18 Schering Aktiengesellschaft 11β-aryl-gona-4,9-dien-3-ones
ZA94715B (en) * 1993-02-08 1994-10-24 Akzo Nv Steroids for treating menopausal complaints
IL123195A (en) * 1997-02-21 2002-11-10 Akzo Nobel Nv Steroid compounds with anti-pregnancy activity and against bone thinning, preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
AU5541298A (en) 1998-08-27
HUP9800373A2 (hu) 1998-11-30
DE69801539T2 (de) 2002-04-18
NO310724B1 (no) 2001-08-20
ZA981344B (en) 1998-08-27
CA2229960A1 (en) 1998-08-21
JP4392066B2 (ja) 2009-12-24
KR19980071540A (ko) 1998-10-26
NO980737L (no) 1998-08-24
CA2229960C (en) 2007-12-18
TW403736B (en) 2000-09-01
IL123195A0 (en) 1998-09-24
BR9800718A (pt) 1999-06-29
TR199800282A1 (xx) 1998-09-21
DK0869132T3 (da) 2002-01-07
IL123195A (en) 2002-11-10
US6077873A (en) 2000-06-20
JPH10273499A (ja) 1998-10-13
US6313180B1 (en) 2001-11-06
PL324939A1 (en) 1998-08-31
HU223755B1 (hu) 2005-01-28
PL188079B1 (pl) 2004-12-31
CN100522984C (zh) 2009-08-05
NO980737D0 (no) 1998-02-20
NZ329789A (en) 1999-09-29
ATE205217T1 (de) 2001-09-15
EP0869132A1 (en) 1998-10-07
RU2182153C2 (ru) 2002-05-10
HU9800373D0 (en) 1998-04-28
ID19947A (id) 1998-08-27
BR9800718B1 (pt) 2009-08-11
ES2164400T3 (es) 2002-02-16
AR011680A1 (es) 2000-08-30
AU723713B2 (en) 2000-09-07
MX9801428A (es) 1998-12-31
HUP9800373A3 (en) 1999-06-28
CN1197076A (zh) 1998-10-28
HK1016188A1 (en) 1999-10-29
PT869132E (pt) 2002-01-30
CN101092442A (zh) 2007-12-26
DE69801539D1 (de) 2001-10-11
CZ50598A3 (cs) 1998-09-16
EP0869132B1 (en) 2001-09-05

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