SG74590G - Substituted dipeptides,methods for their production,pharmaceutical compositions containing them,method for making such pharmaceutical compositions - Google Patents
Substituted dipeptides,methods for their production,pharmaceutical compositions containing them,method for making such pharmaceutical compositionsInfo
- Publication number
- SG74590G SG74590G SG745/90A SG74590A SG74590G SG 74590 G SG74590 G SG 74590G SG 745/90 A SG745/90 A SG 745/90A SG 74590 A SG74590 A SG 74590A SG 74590 G SG74590 G SG 74590G
- Authority
- SG
- Singapore
- Prior art keywords
- pharmaceutical compositions
- making
- production
- methods
- compositions containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 2
- 108010016626 Dipeptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/373—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in doubly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/89—Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ20100182A NZ201001A (en) | 1982-06-17 | 1982-06-17 | Substituted dipeptide derivatives and method of preparation |
| US44476182A | 1982-11-26 | 1982-11-26 | |
| US48346383A | 1983-04-11 | 1983-04-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG74590G true SG74590G (en) | 1990-11-23 |
Family
ID=27353496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG745/90A SG74590G (en) | 1982-06-17 | 1990-09-08 | Substituted dipeptides,methods for their production,pharmaceutical compositions containing them,method for making such pharmaceutical compositions |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0103077B1 (fr) |
| DE (1) | DE3376649D1 (fr) |
| HK (1) | HK14091A (fr) |
| IE (1) | IE55836B1 (fr) |
| MY (1) | MY101775A (fr) |
| SG (1) | SG74590G (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4939261A (en) * | 1984-06-08 | 1990-07-03 | Ciba-Geigy Corporation | N-substituted butyramide derivatives useful for treatment of conditions responsive to inhibition of enkephalinase |
| US5166212A (en) * | 1985-12-06 | 1992-11-24 | Ciba-Geigy Corporation | Certain n-substituted butyramide derivatives |
| EP0225292A3 (fr) * | 1985-12-06 | 1988-11-30 | Ciba-Geigy Ag | Certains dérivés de butyramide N-substitués |
| GB8820844D0 (en) * | 1988-09-05 | 1988-10-05 | Pfizer Ltd | Therapeutic agents |
| AU1870292A (en) * | 1991-04-16 | 1992-11-17 | Schering Corporation | Use of neutral endopeptidase inhibitors in the treatment of nephrotoxicity |
| JP5420761B2 (ja) | 2009-05-28 | 2014-02-19 | ノバルティス アーゲー | ネプリリシン阻害剤としての置換アミノプロピオン酸誘導体 |
| SG176010A1 (en) | 2009-05-28 | 2011-12-29 | Novartis Ag | Substituted aminobutyric derivatives as neprilysin inhibitors |
| JO2967B1 (en) | 2009-11-20 | 2016-03-15 | نوفارتس ايه جي | Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors |
| WO2014126972A1 (fr) | 2013-02-14 | 2014-08-21 | Novartis Ag | Dérivés de l'acide butanoïque bisphényle substitué utiles en tant qu'inhibiteurs de nep présentant une meilleure efficacité in vivo |
| NZ710574A (en) | 2013-02-14 | 2017-11-24 | Novartis Ag | Substituted bisphenyl butanoic phosphonic acid derivatives as nep (neutral endopeptidase) inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL58849A (en) * | 1978-12-11 | 1983-03-31 | Merck & Co Inc | Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them |
| FR2480747A1 (fr) * | 1980-04-17 | 1981-10-23 | Roques Bernard | Derives d'acides amines et leur application therapeutique |
| EP0050800B2 (fr) * | 1980-10-23 | 1995-06-07 | Schering Corporation | Dipeptides carboxyalcoyliques, procédés pour les préparer et compositions pharmaceutiques les contenant |
| EP0054862B1 (fr) * | 1980-12-18 | 1985-11-27 | Schering Corporation | Dipeptides substitués, leur procédé de préparation, compositions pharmaceutiques les contenant et leur emploi comme inhibiteurs de l'enképhalinase |
-
1983
- 1983-06-11 EP EP83105748A patent/EP0103077B1/fr not_active Expired
- 1983-06-11 DE DE8383105748T patent/DE3376649D1/de not_active Expired
- 1983-06-16 IE IE1419/83A patent/IE55836B1/en not_active IP Right Cessation
-
1987
- 1987-09-22 MY MYPI87001844A patent/MY101775A/en unknown
-
1990
- 1990-09-08 SG SG745/90A patent/SG74590G/en unknown
-
1991
- 1991-02-28 HK HK140/91A patent/HK14091A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE831419L (en) | 1983-12-17 |
| HK14091A (en) | 1991-03-08 |
| IE55836B1 (en) | 1991-01-30 |
| EP0103077A2 (fr) | 1984-03-21 |
| EP0103077A3 (en) | 1984-07-25 |
| DE3376649D1 (en) | 1988-06-23 |
| MY101775A (en) | 1992-01-17 |
| EP0103077B1 (fr) | 1988-05-18 |
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