SI20331A - Bazične soli N-/N-(3,3-dimetilbutil)-L-alfa-aspartil/-L-fenilalanin 1-metil estra - Google Patents

Bazične soli N-/N-(3,3-dimetilbutil)-L-alfa-aspartil/-L-fenilalanin 1-metil estra Download PDF

Info

Publication number: SI20331A
Authority: SI; Slovenia
Prior art keywords: phenylalanine; aspartyl; dimethylbutyl; methyl ester; group
Prior art date: 1997-09-11

Application number

SI9820063A

Other languages

English (en)

Slovenian (sl)

Inventor

Indra Prakash

Kurt Wachholder

Original Assignee

The Nutrasweet Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-11

Filing date

1998-09-11

Publication date

2001-02-28

1998-09-11 Application filed by The Nutrasweet Company filed Critical The Nutrasweet Company

2001-02-28 Publication of SI20331A publication Critical patent/SI20331A/sl

Links

150000001447 alkali salts Chemical class 0.000 title abstract description 14
235000010357 aspartame Nutrition 0.000 title description 27
229960005190 phenylalanine Drugs 0.000 title description 22
FGOJCPKOOGIRPA-UHFFFAOYSA-N 1-o-tert-butyl 4-o-ethyl 5-oxoazepane-1,4-dicarboxylate Chemical compound CCOC(=O)C1CCN(C(=O)OC(C)(C)C)CCC1=O FGOJCPKOOGIRPA-UHFFFAOYSA-N 0.000 title description 18
239000007788 liquid Substances 0.000 claims abstract description 14
235000013615 non-nutritive sweetener Nutrition 0.000 claims abstract description 12
150000001450 anions Chemical class 0.000 claims abstract description 4
150000003839 salts Chemical class 0.000 claims description 22
HLIAVLHNDJUHFG-UHFFFAOYSA-N neotame Chemical compound CC(C)(C)CCNC(CC(O)=O)C(=O)NC(C(=O)OC)CC1=CC=CC=C1 HLIAVLHNDJUHFG-UHFFFAOYSA-N 0.000 claims description 14
IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 13
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical group CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 9
239000002904 solvent Substances 0.000 claims description 8
239000000203 mixture Substances 0.000 claims description 5
229910052708 sodium Inorganic materials 0.000 claims description 5
229910052742 iron Inorganic materials 0.000 claims description 3
229910052749 magnesium Inorganic materials 0.000 claims description 3
235000003599 food sweetener Nutrition 0.000 abstract description 13
239000003765 sweetening agent Substances 0.000 abstract description 13
HLIAVLHNDJUHFG-HOTGVXAUSA-N neotame Chemical class CC(C)(C)CCN[C@@H](CC(O)=O)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 HLIAVLHNDJUHFG-HOTGVXAUSA-N 0.000 abstract description 7
108010016626 Dipeptides Proteins 0.000 abstract description 3
108010070257 neotame Proteins 0.000 abstract description 3
-1 3,3-dimethylbutyl Chemical group 0.000 description 25
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 21
239000002585 base Substances 0.000 description 12
108010011485 Aspartame Proteins 0.000 description 8
239000000605 aspartame Substances 0.000 description 8
229960003438 aspartame Drugs 0.000 description 8
239000000243 solution Substances 0.000 description 7
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
150000001875 compounds Chemical class 0.000 description 6
XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 6
239000007787 solid Substances 0.000 description 6
230000000007 visual effect Effects 0.000 description 6
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 5
238000002360 preparation method Methods 0.000 description 5
239000007864 aqueous solution Substances 0.000 description 4
239000010802 sludge Substances 0.000 description 4
239000011734 sodium Substances 0.000 description 4
WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 3
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
239000011575 calcium Substances 0.000 description 3
238000004090 dissolution Methods 0.000 description 3
235000013305 food Nutrition 0.000 description 3
239000011777 magnesium Substances 0.000 description 3
238000000034 method Methods 0.000 description 3
239000011736 potassium bicarbonate Substances 0.000 description 3
229910000028 potassium bicarbonate Inorganic materials 0.000 description 3
235000015497 potassium bicarbonate Nutrition 0.000 description 3
TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 3
ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical compound [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 description 2
VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 2
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
239000004384 Neotame Substances 0.000 description 2
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
229930006000 Sucrose Natural products 0.000 description 2
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 2
WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 description 2
239000001099 ammonium carbonate Substances 0.000 description 2
235000012501 ammonium carbonate Nutrition 0.000 description 2
235000013361 beverage Nutrition 0.000 description 2
AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 2
239000000920 calcium hydroxide Substances 0.000 description 2
229910001861 calcium hydroxide Inorganic materials 0.000 description 2
159000000007 calcium salts Chemical class 0.000 description 2
239000000706 filtrate Substances 0.000 description 2
238000001914 filtration Methods 0.000 description 2
VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 description 2
239000000347 magnesium hydroxide Substances 0.000 description 2
229910001862 magnesium hydroxide Inorganic materials 0.000 description 2
235000019412 neotame Nutrition 0.000 description 2
239000003960 organic solvent Substances 0.000 description 2
XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 2
BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
230000006340 racemization Effects 0.000 description 2
125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 description 2
238000002798 spectrophotometry method Methods 0.000 description 2
239000000126 substance Substances 0.000 description 2
239000005720 sucrose Substances 0.000 description 2
239000011701 zinc Substances 0.000 description 2
USFZMSVCRYTOJT-UHFFFAOYSA-N Ammonium acetate Chemical compound N.CC(O)=O USFZMSVCRYTOJT-UHFFFAOYSA-N 0.000 description 1
239000005695 Ammonium acetate Substances 0.000 description 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
206010011224 Cough Diseases 0.000 description 1
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
239000002262 Schiff base Substances 0.000 description 1
150000004753 Schiff bases Chemical class 0.000 description 1
UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
230000001476 alcoholic effect Effects 0.000 description 1
AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 description 1
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
229910052782 aluminium Inorganic materials 0.000 description 1
150000001412 amines Chemical class 0.000 description 1
229940024606 amino acid Drugs 0.000 description 1
150000001413 amino acids Chemical class 0.000 description 1
229940043376 ammonium acetate Drugs 0.000 description 1
235000019257 ammonium acetate Nutrition 0.000 description 1
239000000908 ammonium hydroxide Substances 0.000 description 1
235000011114 ammonium hydroxide Nutrition 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
235000012839 cake mixes Nutrition 0.000 description 1
229910052791 calcium Inorganic materials 0.000 description 1
239000001569 carbon dioxide Substances 0.000 description 1
229910002092 carbon dioxide Inorganic materials 0.000 description 1
235000014171 carbonated beverage Nutrition 0.000 description 1
150000001728 carbonyl compounds Chemical class 0.000 description 1
150000001768 cations Chemical class 0.000 description 1
235000013339 cereals Nutrition 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
230000000052 comparative effect Effects 0.000 description 1
239000003814 drug Substances 0.000 description 1
239000000428 dust Substances 0.000 description 1
238000004108 freeze drying Methods 0.000 description 1
235000015203 fruit juice Nutrition 0.000 description 1
235000015270 fruit-flavoured drink Nutrition 0.000 description 1
235000011852 gelatine desserts Nutrition 0.000 description 1
125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
230000007062 hydrolysis Effects 0.000 description 1
238000006460 hydrolysis reaction Methods 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
159000000003 magnesium salts Chemical class 0.000 description 1
238000002844 melting Methods 0.000 description 1
230000008018 melting Effects 0.000 description 1
230000004048 modification Effects 0.000 description 1
238000012986 modification Methods 0.000 description 1
229910052757 nitrogen Inorganic materials 0.000 description 1
NDLPOXTZKUMGOV-UHFFFAOYSA-N oxo(oxoferriooxy)iron hydrate Chemical compound O.O=[Fe]O[Fe]=O NDLPOXTZKUMGOV-UHFFFAOYSA-N 0.000 description 1
239000013618 particulate matter Substances 0.000 description 1
230000000704 physical effect Effects 0.000 description 1
239000011591 potassium Substances 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
229910000027 potassium carbonate Inorganic materials 0.000 description 1
235000011181 potassium carbonates Nutrition 0.000 description 1
159000000001 potassium salts Chemical class 0.000 description 1
239000000843 powder Substances 0.000 description 1
108090000765 processed proteins & peptides Proteins 0.000 description 1
102000004196 processed proteins & peptides Human genes 0.000 description 1
235000014438 salad dressings Nutrition 0.000 description 1
229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
235000017557 sodium bicarbonate Nutrition 0.000 description 1
229910000029 sodium carbonate Inorganic materials 0.000 description 1
159000000000 sodium salts Chemical class 0.000 description 1
239000011343 solid material Substances 0.000 description 1
239000011877 solvent mixture Substances 0.000 description 1
238000001694 spray drying Methods 0.000 description 1
239000007858 starting material Substances 0.000 description 1
238000003756 stirring Methods 0.000 description 1
235000019605 sweet taste sensations Nutrition 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
239000006188 syrup Substances 0.000 description 1
YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
235000015961 tonic Nutrition 0.000 description 1
230000001256 tonic effect Effects 0.000 description 1
229960000716 tonics Drugs 0.000 description 1
150000003751 zinc Chemical class 0.000 description 1
UGZADUVQMDAIAO-UHFFFAOYSA-L zinc hydroxide Chemical compound [OH-].[OH-].[Zn+2] UGZADUVQMDAIAO-UHFFFAOYSA-L 0.000 description 1
229940007718 zinc hydroxide Drugs 0.000 description 1
229910021511 zinc hydroxide Inorganic materials 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
- A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Nutrition Science (AREA)
Engineering & Computer Science (AREA)
Food Science & Technology (AREA)
Polymers & Plastics (AREA)
Seasonings (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

SI9820063A 1997-09-11 1998-09-11 Bazične soli N-/N-(3,3-dimetilbutil)-L-alfa-aspartil/-L-fenilalanin 1-metil estra SI20331A (sl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US5850697P	1997-09-11	1997-09-11
PCT/US1998/018903 WO1999012957A1 (fr)	1997-09-11	1998-09-11	SELS BASIQUES DE N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER

Publications (1)

Publication Number	Publication Date
SI20331A true SI20331A (sl)	2001-02-28

Family

ID=22017230

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI9820063A SI20331A (sl)	1997-09-11	1998-09-11	Bazične soli N-/N-(3,3-dimetilbutil)-L-alfa-aspartil/-L-fenilalanin 1-metil estra

Country Status (18)

Country	Link
US (1)	US6291004B1 (fr)
EP (1)	EP1012167A1 (fr)
CN (1)	CN1378555A (fr)
AU (1)	AU751006B2 (fr)
BG (1)	BG104322A (fr)
BR (1)	BR9812638A (fr)
CA (1)	CA2303435A1 (fr)
EE (1)	EE200000122A (fr)
HU (1)	HUP0003847A3 (fr)
ID (1)	ID27938A (fr)
IL (1)	IL134913A0 (fr)
LT (1)	LT2000028A (fr)
NO (1)	NO20001269L (fr)
PL (1)	PL339211A1 (fr)
SI (1)	SI20331A (fr)
SK (1)	SK3282000A3 (fr)
TR (1)	TR200000729T2 (fr)
WO (1)	WO1999012957A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6692778B2 (en)	1998-06-05	2004-02-17	Wm. Wrigley Jr. Company	Method of controlling release of N-substituted derivatives of aspartame in chewing gum
US6365216B1 (en)	1999-03-26	2002-04-02	The Nutrasweet Company	Particles of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
WO2000057726A1 (fr) *	1999-03-29	2000-10-05	The Nutrasweet Company	ALIMENTS FONCTIONNELS COMPRENANT UN ESTER DE 1-METHYLE N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE
WO2000069282A1 (fr) *	1999-05-13	2000-11-23	The Nutrasweet Company	Modification du gout et des proprietes physico-chimiques de neotame, a l'aide d'additifs d'acide hydrophobe
AU5127800A (en) *	1999-05-13	2000-12-05	Nutrasweet Company, The	Use of additives to modify the taste characteristics of n-neohexyl-alpha-aspartyl-l-phenylalanine methyl ester
WO2001028590A2 (fr) *	1999-10-19	2001-04-26	The Nutrasweet Company	COMPOSITIONS PHARMACEUTIQUES RENFERMANT UN ESTER N-[N-(3,3-DIMETHYLBUTYL)-1-α-ASPARTYL]-L-PHENYLALANINE METHYL
US20030008047A1 (en) *	2000-03-17	2003-01-09	Schroeder Steve A.	Stability enhancement of sweeteners using salts containing divalent or trivalent cations
US7326430B2 (en) *	2000-07-18	2008-02-05	The Nutrasweet Company	Method of preparing liquid compositions for delivery of N-[N- (3,3-dimethylbutyl-L-α-aspartyl]-L-phenylalanine 1-methyl ester in food and beverage systems
US7923047B2 (en) *	2006-06-30	2011-04-12	Conagra Foods Rdm, Inc.	Seasoning and method for seasoning a food product while reducing dietary sodium intake
US20110097449A1 (en) *	2006-06-30	2011-04-28	Conagra Foods Rdm, Inc.	Seasoning and method for seasoning a food product while reducing dietary sodium intake
US20080003339A1 (en) *	2006-06-30	2008-01-03	Clinton Johnson	Seasoning and method for seasoning a food product utilizing small particle sea salt
US20080008790A1 (en) *	2006-06-30	2008-01-10	Michael Jensen	Seasoned food, seasoning, and method for seasoning a food product
US20080038411A1 (en) *	2006-06-30	2008-02-14	Michael Jensen	Seasoning and method for enhancing and potentiating food flavor
CA2664585C (fr) *	2006-09-27	2015-04-14	Conagra Foods Rdm, Inc.	Assaisonnement et procede d'amelioration et de renforcement des saveurs alimentaires par microencapsulation, associes a une reduction de l'apport en sodium par l'alimentation
US7750631B2 (en) *	2007-06-22	2010-07-06	Morpho Detection, Inc.	Passenger inspection system and methods for using the same
FR3102041B1 (fr)	2019-10-22	2025-02-14	Aroma Sens	Edulcorant pour liquides de cigarette électronique
CN112321676B (zh) *	2020-12-12	2022-06-14	山东诚汇双达药业有限公司	一种纽甜的成盐方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4031258A (en)	1972-03-30	1977-06-21	General Foods Corporation	Inorganic salts of dipeptide sweeteners
CA1028197A (fr)	1973-04-02	1978-03-21	Jeffrey H. Berg	Edulcorant concentre a faible teneur en calories
ES8604766A1 (es) *	1985-09-20	1986-03-16	Palomo Coll Alberto	Procedimiento para la preparacion de nuevas sales fisiologi-camente activas o aceptables de sabor dulce
FR2697844B1 (fr) *	1992-11-12	1995-01-27	Claude Nofre	Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
FR2719590B1 (fr)	1994-05-09	1996-07-26	Claude Nofre	Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant.
BE1009660A3 (nl) *	1995-10-11	1997-06-03	Holland Sweetener Co	Zoetstofzouten.
IT1281432B1 (it)	1995-10-12	1998-02-18	Gisulfo Baccini	Macchina punzonatrice
US5728862A (en)	1997-01-29	1998-03-17	The Nutrasweet Company	Method for preparing and purifying an N-alkylated aspartame derivative

1998
- 1998-09-04 US US09/146,963 patent/US6291004B1/en not_active Expired - Lifetime
- 1998-09-11 SK SK328-2000A patent/SK3282000A3/sk unknown
- 1998-09-11 IL IL13491398A patent/IL134913A0/xx unknown
- 1998-09-11 WO PCT/US1998/018903 patent/WO1999012957A1/fr not_active Ceased
- 1998-09-11 CN CN98811057A patent/CN1378555A/zh active Pending
- 1998-09-11 BR BR9812638-5A patent/BR9812638A/pt not_active Application Discontinuation
- 1998-09-11 CA CA002303435A patent/CA2303435A1/fr not_active Abandoned
- 1998-09-11 SI SI9820063A patent/SI20331A/sl unknown
- 1998-09-11 HU HU0003847A patent/HUP0003847A3/hu unknown
- 1998-09-11 EE EEP200000122A patent/EE200000122A/xx unknown
- 1998-09-11 ID IDW20000472D patent/ID27938A/id unknown
- 1998-09-11 EP EP98946026A patent/EP1012167A1/fr not_active Withdrawn
- 1998-09-11 PL PL98339211A patent/PL339211A1/xx unknown
- 1998-09-11 AU AU93136/98A patent/AU751006B2/en not_active Ceased
- 1998-09-11 TR TR2000/00729T patent/TR200000729T2/xx unknown
2000
- 2000-03-10 NO NO20001269A patent/NO20001269L/no not_active Application Discontinuation
- 2000-04-06 LT LT2000028A patent/LT2000028A/lt unknown
- 2000-04-10 BG BG104322A patent/BG104322A/xx unknown

Also Published As

Publication number	Publication date
SK3282000A3 (en)	2000-10-09
BG104322A (en)	2001-02-28
EE200000122A (et)	2000-12-15
EP1012167A1 (fr)	2000-06-28
PL339211A1 (en)	2000-12-04
NO20001269L (no)	2000-05-10
CA2303435A1 (fr)	1999-03-18
ID27938A (id)	2001-05-03
BR9812638A (pt)	2000-08-22
HUP0003847A2 (hu)	2002-01-28
AU751006B2 (en)	2002-08-08
LT2000028A (lt)	2000-12-27
WO1999012957A1 (fr)	1999-03-18
HUP0003847A3 (en)	2002-06-28
US6291004B1 (en)	2001-09-18
IL134913A0 (en)	2001-05-20
CN1378555A (zh)	2002-11-06
NO20001269D0 (no)	2000-03-10
AU9313698A (en)	1999-03-29
TR200000729T2 (tr)	2002-01-21

Publication	Publication Date	Title
US6291004B1 (en)	2001-09-18	Basic salts of n-[n-(3,3-dimethylbutyl)-l-α-aspartyl]-l-phenylalanine 1-methyl ester
US4448716A (en)	1984-05-15	Dipeptide sweetener-metal complexes
SI20329A (sl)	2001-02-28	Kovinski kompleksi N-/N-(3,3-dimetilbutil)-L-alfa-aspartil/-L-fenilalanin 1-metil estra
SI20328A (sl)	2001-02-28	Sladilne soli N-/N-(3,3-dimetilbutil)-L-alfa-aspartil/-L-fenilalanin 1-metil estra
SI20330A (sl)	2001-02-28	Kisle soli N-/N-(3,3-dimetilbutil)-L-alfa-aspartil/-L-fenilalanin 1-metil estra
US20030008047A1 (en)	2003-01-09	Stability enhancement of sweeteners using salts containing divalent or trivalent cations
MXPA00002539A (en)	2001-11-21	BASIC SALTS OF N-[N-(3,3-DIMETHYLBUTYL)-L-&agr;-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER
CZ2000814A3 (cs)	2000-10-11	Zásadité soli 1-metylesteru N-[N-(3,3- dimetylbutyl)-L-alfa-aspartyl]-L-fenylalaninu
MXPA00002552A (en)	2001-11-21	METAL COMPLEXES OF N-[N-(3,3-DIMETHYLBUTYL) -L-&agr;-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER
CZ2000815A3 (cs)	2000-10-11	Kyselé soli 1-metylesteru N-[N-(3,3- dimetylbutyl)-L-alfa-aspartyl]-L-fenylalaninu
CZ2000818A3 (cs)	2000-10-11	Komplexy 1-metylesteru N-[N-(3,3-dimetylbutyl)- L-alfa-aspartyl]-L-fenylalaninu s kovy
MXPA00002540A (en)	2001-11-21	ACID SALTS OF N-[N-(3,3-DIMETHYLBUTYL)-L-&agr;-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER