Classifications

• • C—CHEMISTRY; METALLURGY
  • C07—ORGANIC CHEMISTRY
  • C07K—PEPTIDES
  • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
  • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
  • C07K14/575—Hormones
  • C07K14/62—Insulins
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
  • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
  • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
  • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
  • A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
  • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
  • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
  • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
  • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
  • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
  • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K9/00—Medicinal preparations characterised by special physical form
  • A61K9/0012—Galenical forms characterised by the site of application
  • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K9/00—Medicinal preparations characterised by special physical form
  • A61K9/0012—Galenical forms characterised by the site of application
  • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
  • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P3/00—Drugs for disorders of the metabolism
  • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
  • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
• • C—CHEMISTRY; METALLURGY
  • C07—ORGANIC CHEMISTRY
  • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
  • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
  • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
• • C—CHEMISTRY; METALLURGY
  • C07—ORGANIC CHEMISTRY
  • C07K—PEPTIDES
  • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
  • C07K1/14—Extraction; Separation; Purification
  • C07K1/16—Extraction; Separation; Purification by chromatography
  • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
• • C—CHEMISTRY; METALLURGY
  • C07—ORGANIC CHEMISTRY
  • C07K—PEPTIDES
  • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
  • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
  • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
  • C07K16/2869—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
• • C—CHEMISTRY; METALLURGY
  • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
  • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
  • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
  • C12N15/09—Recombinant DNA-technology
  • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
  • C12N15/62—DNA sequences coding for fusion proteins
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K38/00—Medicinal preparations containing peptides
• • C—CHEMISTRY; METALLURGY
  • C07—ORGANIC CHEMISTRY
  • C07K—PEPTIDES
  • C07K2317/00—Immunoglobulins specific features
  • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
  • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
• • C—CHEMISTRY; METALLURGY
  • C07—ORGANIC CHEMISTRY
  • C07K—PEPTIDES
  • C07K2319/00—Fusion polypeptide
  • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

• Health & Medical Sciences (AREA)
• Chemical & Material Sciences (AREA)
• Life Sciences & Earth Sciences (AREA)
• Engineering & Computer Science (AREA)
• General Health & Medical Sciences (AREA)
• Organic Chemistry (AREA)
• Medicinal Chemistry (AREA)
• Bioinformatics & Cheminformatics (AREA)
• Diabetes (AREA)
• Genetics & Genomics (AREA)
• Animal Behavior & Ethology (AREA)
• Veterinary Medicine (AREA)
• Public Health (AREA)
• Pharmacology & Pharmacy (AREA)
• Molecular Biology (AREA)
• Biochemistry (AREA)
• Proteomics, Peptides & Aminoacids (AREA)
• Endocrinology (AREA)
• Epidemiology (AREA)
• Biophysics (AREA)
• Zoology (AREA)
• Dermatology (AREA)
• Immunology (AREA)
• Biomedical Technology (AREA)
• Hematology (AREA)
• Toxicology (AREA)
• Obesity (AREA)
• Gastroenterology & Hepatology (AREA)
• Chemical Kinetics & Catalysis (AREA)
• General Chemical & Material Sciences (AREA)
• Emergency Medicine (AREA)
• Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
• Biotechnology (AREA)
• General Engineering & Computer Science (AREA)
• Wood Science & Technology (AREA)
• Physics & Mathematics (AREA)
• Neurology (AREA)
• Plant Pathology (AREA)
• Microbiology (AREA)
• Analytical Chemistry (AREA)

Applications Claiming Priority (16)

Publications (1)

Family

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Family Applications (4)

Family Applications Before (3)

Country Status (15)

Families Citing this family (31)

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• 2019
  • 2019-06-28 CN CN201980056947.5A patent/CN113038964B/zh active Active
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  • 2019-06-28 JP JP2020573352A patent/JP7417277B2/ja active Active
  • 2019-06-28 SI SI201930152T patent/SI3655006T1/sl unknown
  • 2019-06-28 LT LTEP21164434.9T patent/LT3892628T/lt unknown
  • 2019-06-28 EP EP21207279.7A patent/EP4011908B1/en active Active
  • 2019-06-28 EP EP22203969.5A patent/EP4186920B1/en active Active
  • 2019-06-28 DK DK21207279.7T patent/DK4011908T5/da active
  • 2019-06-28 LT LTEPPCT/US2019/040010T patent/LT3655006T/lt unknown
  • 2019-06-28 KR KR1020257030539A patent/KR20250139414A/ko active Pending
  • 2019-06-28 EP EP21164434.9A patent/EP3892628B1/en active Active
  • 2019-06-28 HU HUE19826154A patent/HUE058005T2/hu unknown
  • 2019-06-28 DK DK22203969.5T patent/DK4186920T5/da active
  • 2019-06-28 CA CA3104144A patent/CA3104144A1/en active Pending
  • 2019-06-28 KR KR1020217002135A patent/KR20210029210A/ko not_active Ceased
  • 2019-06-28 HU HUE22203969A patent/HUE065725T2/hu unknown
  • 2019-06-28 DK DK21164434.9T patent/DK3892628T3/da active
  • 2019-06-28 DK DK19826154.7T patent/DK3655006T3/da active
  • 2019-06-28 EP EP23215091.2A patent/EP4344738A3/en active Pending
  • 2019-06-28 SI SI201930726T patent/SI4186920T1/sl unknown
  • 2019-06-28 BR BR112020026777-5A patent/BR112020026777A2/pt unknown
  • 2019-06-28 FI FIEP22203969.5T patent/FI4186920T3/fi active
  • 2019-06-28 WO PCT/US2019/040010 patent/WO2020006529A1/en not_active Ceased
  • 2019-06-28 HR HRP20240408TT patent/HRP20240408T1/hr unknown
  • 2019-06-28 AU AU2019291945A patent/AU2019291945B2/en active Active
  • 2019-06-28 HR HRP20220091TT patent/HRP20220091T1/hr unknown
  • 2019-06-28 HU HUE21207279A patent/HUE062719T2/hu unknown
  • 2019-06-28 HR HRP20230991TT patent/HRP20230991T1/hr unknown
  • 2019-06-28 CN CN202510816279.9A patent/CN120665204A/zh active Pending
  • 2019-06-28 EP EP19826154.7A patent/EP3655006B1/en active Active
  • 2019-06-28 SI SI201930392T patent/SI3892628T1/sl unknown
  • 2019-06-28 LT LTEP22203969.5T patent/LT4186920T/lt unknown
  • 2019-06-28 HR HRP20221418TT patent/HRP20221418T1/hr unknown
  • 2019-06-28 FI FIEP21207279.7T patent/FI4011908T3/fi active
  • 2019-06-28 HU HUE21164434A patent/HUE060471T2/hu unknown
  • 2019-06-28 SI SI201930615T patent/SI4011908T1/sl unknown
• 2020
  • 2020-01-29 US US16/776,065 patent/US10870686B2/en active Active
  • 2020-01-29 US US16/775,979 patent/US10961294B2/en active Active
  • 2020-01-29 US US16/776,136 patent/US10947292B2/en active Active
  • 2020-01-29 US US16/776,180 patent/US10851147B2/en active Active
  • 2020-09-11 US US17/019,059 patent/US11261229B2/en active Active
• 2021
  • 2021-09-29 US US17/488,852 patent/US11773151B2/en active Active
  • 2021-09-29 US US17/488,685 patent/US11673934B2/en active Active
• 2023
  • 2023-09-01 US US18/459,581 patent/US20240101635A1/en not_active Abandoned
  • 2023-12-25 JP JP2023217822A patent/JP7510728B2/ja active Active
• 2024
  • 2024-12-23 AU AU2024287186A patent/AU2024287186A1/en active Pending
• 2025
  • 2025-02-21 US US19/060,483 patent/US20250289863A1/en active Pending

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