SI9300525A - Injection solution containing mesna - Google Patents

Injection solution containing mesna Download PDF

Info

Publication number: SI9300525A
Authority: SI; Slovenia
Prior art keywords: solution; meat; injection; water; weight
Prior art date: 1992-10-08

Application number

SI9300525A

Other languages

English (en)

Slovenian (sl)

Inventor

Jurgen Engel

Elisabeth Wolf-Heuss

Wolfgang Deger

Giancarlo Camuglia

Dieter Sauerbier

Original Assignee

Asta Medica Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-10-08

Filing date

1993-10-05

Publication date

1994-06-30

1993-10-05 Application filed by Asta Medica Ag filed Critical Asta Medica Ag

1994-06-30 Publication of SI9300525A publication Critical patent/SI9300525A/sl

Links

239000000243 solution Substances 0.000 title claims abstract description 38
238000002347 injection Methods 0.000 title claims abstract description 26
239000007924 injection Substances 0.000 title claims abstract description 26
229960004635 mesna Drugs 0.000 title claims abstract description 4
XOGTZOOQQBDUSI-UHFFFAOYSA-M Mesna Chemical compound [Na+].[O-]S(=O)(=O)CCS XOGTZOOQQBDUSI-UHFFFAOYSA-M 0.000 title claims abstract 3
238000002360 preparation method Methods 0.000 claims abstract description 5
235000013372 meat Nutrition 0.000 claims description 22
239000003814 drug Substances 0.000 claims description 6
239000000126 substance Substances 0.000 claims description 4
238000000034 method Methods 0.000 claims description 3
238000004519 manufacturing process Methods 0.000 claims description 2
ZZVDXRCAGGQFAK-UHFFFAOYSA-N 2h-oxazaphosphinine Chemical class N1OC=CC=P1 ZZVDXRCAGGQFAK-UHFFFAOYSA-N 0.000 claims 1
WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 21
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 18
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 17
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 12
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 8
239000001301 oxygen Substances 0.000 description 8
229910052760 oxygen Inorganic materials 0.000 description 8
229960004217 benzyl alcohol Drugs 0.000 description 7
235000019445 benzyl alcohol Nutrition 0.000 description 7
229910052757 nitrogen Inorganic materials 0.000 description 6
239000011521 glass Substances 0.000 description 5
239000003755 preservative agent Substances 0.000 description 5
HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 description 4
229940079593 drug Drugs 0.000 description 4
238000001914 filtration Methods 0.000 description 4
239000012535 impurity Substances 0.000 description 4
239000011734 sodium Substances 0.000 description 4
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
239000002253 acid Substances 0.000 description 3
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
239000012141 concentrate Substances 0.000 description 3
HOMGKSMUEGBAAB-UHFFFAOYSA-N ifosfamide Chemical compound ClCCNP1(=O)OCCCN1CCCl HOMGKSMUEGBAAB-UHFFFAOYSA-N 0.000 description 3
229960001101 ifosfamide Drugs 0.000 description 3
230000002335 preservative effect Effects 0.000 description 3
229910052708 sodium Inorganic materials 0.000 description 3
229940037001 sodium edetate Drugs 0.000 description 3
230000001954 sterilising effect Effects 0.000 description 3
238000004659 sterilization and disinfection Methods 0.000 description 3
UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 3
239000003795 chemical substances by application Substances 0.000 description 2
OSASVXMJTNOKOY-UHFFFAOYSA-N chlorobutanol Chemical compound CC(C)(O)C(Cl)(Cl)Cl OSASVXMJTNOKOY-UHFFFAOYSA-N 0.000 description 2
238000004140 cleaning Methods 0.000 description 2
239000012459 cleaning agent Substances 0.000 description 2
ZNEWHQLOPFWXOF-UHFFFAOYSA-N coenzyme M Chemical compound OS(=O)(=O)CCS ZNEWHQLOPFWXOF-UHFFFAOYSA-N 0.000 description 2
239000008139 complexing agent Substances 0.000 description 2
238000003958 fumigation Methods 0.000 description 2
239000003978 infusion fluid Substances 0.000 description 2
239000000203 mixture Substances 0.000 description 2
QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 description 2
238000003860 storage Methods 0.000 description 2
QTWJRLJHJPIABL-UHFFFAOYSA-N 2-methylphenol;3-methylphenol;4-methylphenol Chemical compound CC1=CC=C(O)C=C1.CC1=CC=CC(O)=C1.CC1=CC=CC=C1O QTWJRLJHJPIABL-UHFFFAOYSA-N 0.000 description 1
229940090248 4-hydroxybenzoic acid Drugs 0.000 description 1
241000894006 Bacteria Species 0.000 description 1
FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
241000289669 Erinaceus europaeus Species 0.000 description 1
241001274216 Naso Species 0.000 description 1
206010028980 Neoplasm Diseases 0.000 description 1
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical class OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 1
VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 1
FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
RXDLGFMMQFNVLI-UHFFFAOYSA-N [Na].[Na].[Ca] Chemical compound [Na].[Na].[Ca] RXDLGFMMQFNVLI-UHFFFAOYSA-N 0.000 description 1
DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 description 1
125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
230000001580 bacterial effect Effects 0.000 description 1
229960004926 chlorobutanol Drugs 0.000 description 1
235000015165 citric acid Nutrition 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
239000000356 contaminant Substances 0.000 description 1
238000011109 contamination Methods 0.000 description 1
229930003836 cresol Natural products 0.000 description 1
238000000354 decomposition reaction Methods 0.000 description 1
230000007547 defect Effects 0.000 description 1
239000007857 degradation product Substances 0.000 description 1
229950009278 dimesna Drugs 0.000 description 1
ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 1
229910000396 dipotassium phosphate Inorganic materials 0.000 description 1
235000019797 dipotassium phosphate Nutrition 0.000 description 1
201000010099 disease Diseases 0.000 description 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
229960002628 disodium salt edetic acid Drugs 0.000 description 1
KQYGMURBTJPBPQ-UHFFFAOYSA-L disodium;2-(2-sulfonatoethyldisulfanyl)ethanesulfonate Chemical compound [Na+].[Na+].[O-]S(=O)(=O)CCSSCCS([O-])(=O)=O KQYGMURBTJPBPQ-UHFFFAOYSA-L 0.000 description 1
239000000835 fiber Substances 0.000 description 1
229910001385 heavy metal Inorganic materials 0.000 description 1
230000007062 hydrolysis Effects 0.000 description 1
238000006460 hydrolysis reaction Methods 0.000 description 1
208000015181 infectious disease Diseases 0.000 description 1
238000001802 infusion Methods 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
239000007788 liquid Substances 0.000 description 1
239000000463 material Substances 0.000 description 1
239000012528 membrane Substances 0.000 description 1
230000000813 microbial effect Effects 0.000 description 1
230000001878 mycolytic effect Effects 0.000 description 1
229960005419 nitrogen Drugs 0.000 description 1
239000002736 nonionic surfactant Substances 0.000 description 1
210000000056 organ Anatomy 0.000 description 1
230000003647 oxidation Effects 0.000 description 1
238000007254 oxidation reaction Methods 0.000 description 1
-1 p - hydroxybenzoic acid ester Chemical class 0.000 description 1
238000010979 pH adjustment Methods 0.000 description 1
238000001139 pH measurement Methods 0.000 description 1
FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
238000007911 parenteral administration Methods 0.000 description 1
239000003182 parenteral nutrition solution Substances 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
150000003014 phosphoric acid esters Chemical class 0.000 description 1
239000011148 porous material Substances 0.000 description 1
239000000843 powder Substances 0.000 description 1
238000011045 prefiltration Methods 0.000 description 1
239000000047 product Substances 0.000 description 1
150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
238000007789 sealing Methods 0.000 description 1
239000001632 sodium acetate Substances 0.000 description 1
235000017281 sodium acetate Nutrition 0.000 description 1
239000001509 sodium citrate Substances 0.000 description 1
239000002904 solvent Substances 0.000 description 1
238000011146 sterile filtration Methods 0.000 description 1
238000003756 stirring Methods 0.000 description 1
239000011975 tartaric acid Substances 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
229940038773 trisodium citrate Drugs 0.000 description 1
229960000281 trometamol Drugs 0.000 description 1
210000001635 urinary tract Anatomy 0.000 description 1
239000008215 water for injection Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/105—Persulfides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/12—Mucolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cosmetics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Superconductors And Manufacturing Methods Therefor (AREA)
Peptides Or Proteins (AREA)
Filling Or Discharging Of Gas Storage Vessels (AREA)
Luminescent Compositions (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)

SI9300525A 1992-10-08 1993-10-05 Injection solution containing mesna SI9300525A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4233842A DE4233842A1 (de)	1992-10-08	1992-10-08	Mesna Injektionslösungen

Publications (1)

Publication Number	Publication Date
SI9300525A true SI9300525A (en)	1994-06-30

Family

ID=6469925

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI9300525A SI9300525A (en)	1992-10-08	1993-10-05	Injection solution containing mesna

Country Status (28)

Country	Link
US (2)	US5728738A (fr)
EP (1)	EP0591710B1 (fr)
JP (1)	JP3636372B2 (fr)
KR (1)	KR100364466B1 (fr)
CN (1)	CN1071114C (fr)
AT (1)	ATE139693T1 (fr)
AU (1)	AU667129B2 (fr)
BR (1)	BR9304151A (fr)
CA (1)	CA2107961C (fr)
CZ (1)	CZ284584B6 (fr)
DE (2)	DE4233842A1 (fr)
DK (1)	DK0591710T3 (fr)
EG (1)	EG20308A (fr)
ES (1)	ES2089661T3 (fr)
FI (1)	FI111804B (fr)
GR (1)	GR3020669T3 (fr)
HK (1)	HK7397A (fr)
HR (1)	HRP931267B1 (fr)
HU (1)	HU217123B (fr)
IL (1)	IL107187A (fr)
NO (1)	NO303712B1 (fr)
NZ (1)	NZ248873A (fr)
RU (1)	RU2105550C1 (fr)
SI (1)	SI9300525A (fr)
SK (1)	SK279609B6 (fr)
TW (1)	TW279131B (fr)
UA (1)	UA26134C2 (fr)
ZA (1)	ZA937458B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6828415B2 (en) *	1993-02-19	2004-12-07	Zentaris Gmbh	Oligopeptide lyophilisate, their preparation and use
IT1284973B1 (it) *	1996-10-11	1998-05-28	A R D O Associazione Ricerca E	Uso del sodio 2-mercaptoetansolfonato (mesna) in chirurgia
US6031006A (en) *	1999-10-21	2000-02-29	Bionumerik Pharmaceuticals, Inc.	Method of treating diabetic nephropathy
TW201036529A (en)	2009-03-25	2010-10-01	Askey Computer Corp	A liquid crystal anti-freeze method and a liquid crystal module using the liquid crystal anti-freeze method
UA74097U (ru) *	2012-07-24	2012-10-10	Николай Иванович Гуменюк	Способ изготовления средства для лечения туберкулеза
US10092312B2 (en) *	2013-05-07	2018-10-09	Auxin Surgery Sa	Device for chemically assisted dissection
WO2017157670A1 (fr)	2016-03-14	2017-09-21	Auxin Surgery Sa	Dispositif, procédé et formulation pour dissection assistée chimiquement
BE1024110B1 (fr) *	2016-10-18	2017-11-16	Auxin Surgery Sa	Dispositif, procédé et formulation pour dissection assistée de manière chimique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3111770A1 (de) *	1981-03-25	1982-10-07	Heyl Chemisch-pharmazeutische Fabrik GmbH & Co KG, 1000 Berlin	Verwendung von dimercaptopropansulfonsaeure und dimercaptobernsteinsaeure zur herstellung von pharmazeutischen mitteln
IT1185551B (it) *	1985-04-15	1987-11-12	Schering Spa	Composizioni farmaceutiche a base di acido mercaptoetansolfonico ad attivita' terapeutica,derivati salini organici dell'acido mercaptoetansolfonico utili per tali composizioni e relativo procedimento di preparazione
EP0334083B1 (fr) *	1988-03-19	1991-07-24	ASTA Pharma Aktiengesellschaft	Composition lyophilisée à base de ifosfamide-mesna et procédé pour sa préparation

1992
- 1992-10-08 DE DE4233842A patent/DE4233842A1/de not_active Withdrawn
1993
- 1993-08-24 TW TW082106854A patent/TW279131B/zh not_active IP Right Cessation
- 1993-09-13 DE DE59303067T patent/DE59303067D1/de not_active Expired - Lifetime
- 1993-09-13 AT AT93114670T patent/ATE139693T1/de active
- 1993-09-13 EP EP93114670A patent/EP0591710B1/fr not_active Expired - Lifetime
- 1993-09-13 DK DK93114670.8T patent/DK0591710T3/da active
- 1993-09-13 ES ES93114670T patent/ES2089661T3/es not_active Expired - Lifetime
- 1993-10-03 EG EG64293A patent/EG20308A/xx active
- 1993-10-05 SI SI9300525A patent/SI9300525A/sl unknown
- 1993-10-05 CN CN93118643A patent/CN1071114C/zh not_active Expired - Lifetime
- 1993-10-05 IL IL10718793A patent/IL107187A/en not_active IP Right Cessation
- 1993-10-06 KR KR1019930020576A patent/KR100364466B1/ko not_active Expired - Lifetime
- 1993-10-06 BR BR9304151A patent/BR9304151A/pt not_active Application Discontinuation
- 1993-10-06 JP JP25042793A patent/JP3636372B2/ja not_active Expired - Lifetime
- 1993-10-06 UA UA93002240A patent/UA26134C2/uk unknown
- 1993-10-06 NZ NZ248873A patent/NZ248873A/en not_active IP Right Cessation
- 1993-10-07 HU HU9302837A patent/HU217123B/hu unknown
- 1993-10-07 CA CA002107961A patent/CA2107961C/fr not_active Expired - Fee Related
- 1993-10-07 SK SK1079-93A patent/SK279609B6/sk not_active IP Right Cessation
- 1993-10-07 FI FI934410A patent/FI111804B/fi not_active IP Right Cessation
- 1993-10-07 CZ CZ932097A patent/CZ284584B6/cs not_active IP Right Cessation
- 1993-10-07 ZA ZA937458A patent/ZA937458B/xx unknown
- 1993-10-07 HR HRP4233842.5A patent/HRP931267B1/xx not_active IP Right Cessation
- 1993-10-07 RU RU93048160A patent/RU2105550C1/ru active
- 1993-10-07 AU AU48883/93A patent/AU667129B2/en not_active Expired
- 1993-10-07 NO NO933590A patent/NO303712B1/no not_active IP Right Cessation
1995
- 1995-06-07 US US08/474,246 patent/US5728738A/en not_active Expired - Lifetime
1996
- 1996-04-23 US US08/636,821 patent/US5696172A/en not_active Expired - Lifetime
- 1996-07-31 GR GR960402027T patent/GR3020669T3/el unknown
1997
- 1997-01-16 HK HK7397A patent/HK7397A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
HUT65096A (en)	1994-04-28
RU2105550C1 (ru)	1998-02-27
FI111804B (fi)	2003-09-30
GR3020669T3 (en)	1996-10-31
NO303712B1 (no)	1998-08-24
CA2107961A1 (fr)	1994-04-09
NO933590D0 (no)	1993-10-07
CZ284584B6 (cs)	1999-01-13
CZ209793A3 (en)	1994-04-13
KR100364466B1 (ko)	2003-01-29
CN1071114C (zh)	2001-09-19
EP0591710A1 (fr)	1994-04-13
FI934410L (fi)	1994-04-09
TW279131B (fr)	1996-06-21
NZ248873A (en)	1995-10-26
JPH06263629A (ja)	1994-09-20
CN1089137A (zh)	1994-07-13
DE4233842A1 (de)	1994-04-14
HRP931267B1 (en)	1997-08-31
HK7397A (en)	1997-01-24
US5728738A (en)	1998-03-17
NO933590L (no)	1994-04-11
HU217123B (hu)	1999-11-29
KR940008678A (ko)	1994-05-16
ATE139693T1 (de)	1996-07-15
AU4888393A (en)	1994-04-21
US5696172A (en)	1997-12-09
UA26134C2 (uk)	1999-06-07
EP0591710B1 (fr)	1996-06-26
FI934410A0 (fi)	1993-10-07
ES2089661T3 (es)	1996-10-01
ZA937458B (en)	1994-04-26
JP3636372B2 (ja)	2005-04-06
BR9304151A (pt)	1994-06-07
HU9302837D0 (en)	1993-12-28
EG20308A (en)	1998-10-31
DK0591710T3 (da)	1996-09-30
DE59303067D1 (de)	1996-08-01
HRP931267A2 (en)	1994-12-31
CA2107961C (fr)	2003-03-25
SK279609B6 (sk)	1999-01-11
SK107993A3 (en)	1994-05-11
IL107187A0 (en)	1994-01-25
AU667129B2 (en)	1996-03-07
IL107187A (en)	1999-03-12

Legal Events

Date	Code	Title	Description
2005-01-10	IF	Valid on the event date

Publication	Publication Date	Title
US6992218B2 (en)	2006-01-31	Method for obtaining aqueous formulations of oxidation-sensitive active principles
KR100191873B1 (ko)	1999-06-15	안정화된 pvp-i 용액
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SI9300525A (en)	1994-06-30	Injection solution containing mesna
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US5834520A (en)	1998-11-10	Container for injectable mesna solutions
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JPH0338251B2 (fr)	1991-06-10
HU204436B (en)	1992-01-28	Process for producing parenteral aqouos pharmaceutical composition containing tobramycin, apramycin or gentamycin