SK11232001A3 - Použitie hematopoietickej kmeňovej bunky - Google Patents

Použitie hematopoietickej kmeňovej bunky Download PDF

Info

Publication number: SK11232001A3
Authority: SK; Slovakia
Prior art keywords: cells; disease; transplantation; treatment; hematopoietic stem
Prior art date: 1999-02-24

Application number

SK1123-2001A

Other languages

English (en)

Slovak (sk)

Inventor

Jack Price

Original Assignee

Reneuron Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-02-24

Filing date

2000-02-23

Publication date

2002-01-07

2000-02-23 Application filed by Reneuron Limited filed Critical Reneuron Limited

2002-01-07 Publication of SK11232001A3 publication Critical patent/SK11232001A3/sk

Links

238000002054 transplantation Methods 0.000 title claims abstract description 21
210000004524 haematopoietic cell Anatomy 0.000 title 1
210000004556 brain Anatomy 0.000 claims abstract description 17
201000010099 disease Diseases 0.000 claims abstract description 10
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 10
210000000130 stem cell Anatomy 0.000 claims abstract description 8
208000018737 Parkinson disease Diseases 0.000 claims abstract description 6
208000024827 Alzheimer disease Diseases 0.000 claims abstract description 4
230000008439 repair process Effects 0.000 claims abstract description 4
210000004027 cell Anatomy 0.000 claims description 62
210000003958 hematopoietic stem cell Anatomy 0.000 claims description 18
230000007812 deficiency Effects 0.000 claims description 10
230000001953 sensory effect Effects 0.000 claims description 10
239000003814 drug Substances 0.000 claims description 7
230000003137 locomotive effect Effects 0.000 claims description 5
108090000623 proteins and genes Proteins 0.000 claims description 5
108700020796 Oncogene Proteins 0.000 claims description 4
238000000034 method Methods 0.000 claims description 4
238000004519 manufacturing process Methods 0.000 claims description 3
208000006264 Korsakoff syndrome Diseases 0.000 claims description 2
239000000427 antigen Substances 0.000 claims description 2
108091007433 antigens Proteins 0.000 claims description 2
102000036639 antigens Human genes 0.000 claims description 2
230000001225 therapeutic effect Effects 0.000 claims description 2
210000000133 brain stem Anatomy 0.000 claims 1
230000003394 haemopoietic effect Effects 0.000 abstract 2
230000006378 damage Effects 0.000 description 14
208000029028 brain injury Diseases 0.000 description 4
210000005260 human cell Anatomy 0.000 description 4
208000027418 Wounds and injury Diseases 0.000 description 3
238000011161 development Methods 0.000 description 3
230000018109 developmental process Effects 0.000 description 3
238000000338 in vitro Methods 0.000 description 3
208000014674 injury Diseases 0.000 description 3
210000001178 neural stem cell Anatomy 0.000 description 3
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238000012360 testing method Methods 0.000 description 3
210000001519 tissue Anatomy 0.000 description 3
206010012289 Dementia Diseases 0.000 description 2
208000010496 Heart Arrest Diseases 0.000 description 2
241000282412 Homo Species 0.000 description 2
241000699670 Mus sp. Species 0.000 description 2
210000004369 blood Anatomy 0.000 description 2
239000008280 blood Substances 0.000 description 2
210000000601 blood cell Anatomy 0.000 description 2
210000001185 bone marrow Anatomy 0.000 description 2
230000006931 brain damage Effects 0.000 description 2
231100000874 brain damage Toxicity 0.000 description 2
230000006735 deficit Effects 0.000 description 2
230000004064 dysfunction Effects 0.000 description 2
238000000605 extraction Methods 0.000 description 2
230000002068 genetic effect Effects 0.000 description 2
239000003102 growth factor Substances 0.000 description 2
230000006872 improvement Effects 0.000 description 2
238000001802 infusion Methods 0.000 description 2
208000028867 ischemia Diseases 0.000 description 2
230000000302 ischemic effect Effects 0.000 description 2
210000001577 neostriatum Anatomy 0.000 description 2
230000004770 neurodegeneration Effects 0.000 description 2
208000015122 neurodegenerative disease Diseases 0.000 description 2
230000000644 propagated effect Effects 0.000 description 2
208000000044 Amnesia Diseases 0.000 description 1
208000031091 Amnestic disease Diseases 0.000 description 1
201000011240 Frontotemporal dementia Diseases 0.000 description 1
208000031220 Hemophilia Diseases 0.000 description 1
208000009292 Hemophilia A Diseases 0.000 description 1
206010021143 Hypoxia Diseases 0.000 description 1
206010061216 Infarction Diseases 0.000 description 1
241000124008 Mammalia Species 0.000 description 1
241001465754 Metazoa Species 0.000 description 1
208000000609 Pick Disease of the Brain Diseases 0.000 description 1
241000700159 Rattus Species 0.000 description 1
230000006986 amnesia Effects 0.000 description 1
210000004102 animal cell Anatomy 0.000 description 1
238000010171 animal model Methods 0.000 description 1
210000001367 artery Anatomy 0.000 description 1
238000003556 assay Methods 0.000 description 1
210000001130 astrocyte Anatomy 0.000 description 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
230000003542 behavioural effect Effects 0.000 description 1
230000036770 blood supply Effects 0.000 description 1
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239000000969 carrier Substances 0.000 description 1
230000011712 cell development Effects 0.000 description 1
230000006727 cell loss Effects 0.000 description 1
206010008129 cerebral palsy Diseases 0.000 description 1
239000013043 chemical agent Substances 0.000 description 1
210000004351 coronary vessel Anatomy 0.000 description 1
238000012937 correction Methods 0.000 description 1
239000003085 diluting agent Substances 0.000 description 1
230000009189 diving Effects 0.000 description 1
229940079593 drug Drugs 0.000 description 1
239000003937 drug carrier Substances 0.000 description 1
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238000002474 experimental method Methods 0.000 description 1
230000004077 genetic alteration Effects 0.000 description 1
231100000118 genetic alteration Toxicity 0.000 description 1
239000001963 growth medium Substances 0.000 description 1
208000018706 hematopoietic system disease Diseases 0.000 description 1
230000000971 hippocampal effect Effects 0.000 description 1
230000007954 hypoxia Effects 0.000 description 1
230000007574 infarction Effects 0.000 description 1
230000003902 lesion Effects 0.000 description 1
210000000265 leukocyte Anatomy 0.000 description 1
230000007774 longterm Effects 0.000 description 1
210000004698 lymphocyte Anatomy 0.000 description 1
239000000463 material Substances 0.000 description 1
230000007246 mechanism Effects 0.000 description 1
238000000520 microinjection Methods 0.000 description 1
239000000203 mixture Substances 0.000 description 1
210000000066 myeloid cell Anatomy 0.000 description 1
208000010125 myocardial infarction Diseases 0.000 description 1
210000003061 neural cell Anatomy 0.000 description 1
230000001537 neural effect Effects 0.000 description 1
229910052760 oxygen Inorganic materials 0.000 description 1
239000001301 oxygen Substances 0.000 description 1
230000001575 pathological effect Effects 0.000 description 1
230000009984 peri-natal effect Effects 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
239000002243 precursor Substances 0.000 description 1
230000004044 response Effects 0.000 description 1
208000007056 sickle cell anemia Diseases 0.000 description 1
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230000001502 supplementing effect Effects 0.000 description 1
230000009182 swimming Effects 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
230000000451 tissue damage Effects 0.000 description 1
231100000827 tissue damage Toxicity 0.000 description 1
230000002463 transducing effect Effects 0.000 description 1
230000005740 tumor formation Effects 0.000 description 1
230000002861 ventricular Effects 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Psychology (AREA)
Wood Science & Technology (AREA)
Hematology (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Immunology (AREA)
Microbiology (AREA)
Developmental Biology & Embryology (AREA)
Hospice & Palliative Care (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Cell Biology (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Materials For Medical Uses (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

SK1123-2001A 1999-02-24 2000-02-23 Použitie hematopoietickej kmeňovej bunky SK11232001A3 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9904281.4A GB9904281D0 (en)	1999-02-24	1999-02-24	Transplantation
PCT/GB2000/000636 WO2000050568A2 (en)	1999-02-24	2000-02-23	Transplantation of haematopoietic cells

Publications (1)

Publication Number	Publication Date
SK11232001A3 true SK11232001A3 (sk)	2002-01-07

Family

ID=10848438

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1123-2001A SK11232001A3 (sk)	1999-02-24	2000-02-23	Použitie hematopoietickej kmeňovej bunky

Country Status (20)

Country	Link
EP (1)	EP1161521B1 (de)
JP (1)	JP4716575B2 (de)
KR (1)	KR20020000216A (de)
CN (1)	CN1636053A (de)
AT (1)	ATE237680T1 (de)
AU (1)	AU762763B2 (de)
CA (1)	CA2361401A1 (de)
CZ (1)	CZ20012651A3 (de)
DE (1)	DE60002185T2 (de)
DK (1)	DK1161521T3 (de)
ES (1)	ES2193938T3 (de)
GB (1)	GB9904281D0 (de)
HK (1)	HK1041284B (de)
HU (1)	HUP0105168A3 (de)
NO (1)	NO20014091L (de)
PL (1)	PL350297A1 (de)
PT (1)	PT1161521E (de)
RU (1)	RU2216336C2 (de)
SK (1)	SK11232001A3 (de)
WO (1)	WO2000050568A2 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9518606D0 (en)	1995-09-12	1995-11-15	Inst Of Psychiatry	Neural transplantation
US8017112B2 (en)	1999-05-14	2011-09-13	Henry Ford Health System	Transplantation of bone marrow stromal cells for treatment of neurodegenerative diseases
JP2002544234A (ja) *	1999-05-14	2002-12-24	ヘンリーフォードヘルスシステム	発作の処置のための骨髄移植
EP1471970A4 (de) *	2002-01-14	2006-08-02	Univ Illinois	Neue multipotente säugetier-stammzellen und zusammensetzungen, verfahren zur herstellung und verfahren zu ihrer verabreichung
AU2003280824A1 (en) *	2002-11-15	2004-06-15	Fumihiko Ishikawa	Method of organ regeneration
DE602005002430T2 (de)	2004-09-30	2008-06-19	Reneuron Ltd., Guildford	Zelllinie
RU2283121C2 (ru) *	2004-11-29	2006-09-10	Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН	Способ лечения инсульта
RU2283119C1 (ru) *	2005-03-29	2006-09-10	Андрей Степанович БРЮХОВЕЦКИЙ	Препарат аутологичных гемопоэтических стволовых клеток, способ его получения, криоконсервации и использования для лечения травматической болезни центральной нервной системы
US7569545B2 (en) *	2005-05-20	2009-08-04	Academia Sinica	Methods of increasing neurotrophic factor expression
EP3424507A1 (de)	2006-03-24	2019-01-09	Children's Medical Center Corporation	Verfahren zur modulierung des wachstums blutbildender stammzellen
EP2679221B1 (de)	2006-10-20	2020-09-23	Children's Medical Center Corporation	Verfahren zur Verbesserung der Geweberegeneration
RU2315618C1 (ru) *	2006-11-02	2008-01-27	ГОУ ВПО "Красноярская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию"	Способ коррекции постишемической когнитивной дисфункции
EP2326330B1 (de)	2008-09-16	2015-01-07	University Of Central Florida Research Foundation, Inc.	Zusammensetzungen zur behandlung oder verzögerung des beginns von haarverlust
WO2010096264A2 (en)	2009-02-03	2010-08-26	Children's Medical Center Corporation	Methods for enhancing hematopoietic stem/progenitor cell engraftment
WO2010091052A2 (en)	2009-02-03	2010-08-12	Children's Medical Center Corporation	Methods for enhancing hematopoietic stem/progenitor cell engraftment
GB0902034D0 (en)	2009-02-06	2009-03-11	Reneuron Ltd	Method
AU2012245269B2 (en) *	2011-04-20	2016-09-29	The Regents Of The University Of California	Method for combined conditioning and chemoselection in a single cycle
US10111907B2 (en)	2011-12-02	2018-10-30	Fate Therapeutics, Inc.	Methods of treating ischemia
EP3785767A1 (de)	2011-12-02	2021-03-03	Fate Therapeutics, Inc.	Verbesserte stammzellenzusammensetzung
US10851412B2 (en)	2013-03-15	2020-12-01	Fate Therapeutics, Inc.	Cell potency assay for therapeutic potential
RU2647429C1 (ru) *	2017-02-06	2018-03-15	Федеральное государственное автономное образовательное учреждение высшего образования "Дальневосточный федеральный университет" (ДВФУ)	Биомедицинский клеточный препарат
RU2720002C1 (ru) *	2018-12-28	2020-04-23	Андрей Степанович БРЮХОВЕЦКИЙ	Биомедицинский клеточный продукт для лечения нервных болезней и психических расстройств, способ его получения и его применение
CN114934072B (zh) *	2022-05-18	2023-10-20	华中科技大学同济医学院附属协和医院	一种人心脏瓣膜间质细胞系的永生化构建方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5399493A (en) *	1989-06-15	1995-03-21	The Regents Of The University Of Michigan	Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
US5612211A (en) *	1990-06-08	1997-03-18	New York University	Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors
AU680406B2 (en) *	1992-03-04	1997-07-31	Systemix, Inc.	Culturing of hematopoietic stem cells and their genetic engineering
IL122752A (en) *	1995-06-27	2001-07-24	Boehringer Ingelheim Kg	Stable preparations for creating propellant-free sprays
GB9518606D0 (en) *	1995-09-12	1995-11-15	Inst Of Psychiatry	Neural transplantation
RU2129427C1 (ru) *	1996-04-30	1999-04-27	Аникин Александр Юрьевич	Способ лечения заболеваний центральной нервной системы
CA2262817A1 (en) *	1996-08-19	1998-02-26	James Robl	Embryonic or stem-like cell lines produced by cross species nuclear transplantation
RU2136299C1 (ru) *	1998-04-13	1999-09-10	Тамара Михайловна Воробьева	Способ лечения демиелинизирующих расстройств центральной нервной системы

1999
- 1999-02-24 GB GBGB9904281.4A patent/GB9904281D0/en not_active Ceased
2000
- 2000-02-23 WO PCT/GB2000/000636 patent/WO2000050568A2/en not_active Ceased
- 2000-02-23 EP EP00905194A patent/EP1161521B1/de not_active Expired - Lifetime
- 2000-02-23 DK DK00905194T patent/DK1161521T3/da active
- 2000-02-23 DE DE60002185T patent/DE60002185T2/de not_active Expired - Lifetime
- 2000-02-23 AU AU26821/00A patent/AU762763B2/en not_active Ceased
- 2000-02-23 HU HU0105168A patent/HUP0105168A3/hu unknown
- 2000-02-23 PL PL00350297A patent/PL350297A1/xx not_active Application Discontinuation
- 2000-02-23 SK SK1123-2001A patent/SK11232001A3/sk unknown
- 2000-02-23 RU RU2001125914/15A patent/RU2216336C2/ru not_active IP Right Cessation
- 2000-02-23 JP JP2000601132A patent/JP4716575B2/ja not_active Expired - Fee Related
- 2000-02-23 KR KR1020017010773A patent/KR20020000216A/ko not_active Withdrawn
- 2000-02-23 CA CA002361401A patent/CA2361401A1/en not_active Abandoned
- 2000-02-23 ES ES00905194T patent/ES2193938T3/es not_active Expired - Lifetime
- 2000-02-23 AT AT00905194T patent/ATE237680T1/de not_active IP Right Cessation
- 2000-02-23 PT PT00905194T patent/PT1161521E/pt unknown
- 2000-02-23 HK HK02101109.4A patent/HK1041284B/en not_active IP Right Cessation
- 2000-02-23 CZ CZ20012651A patent/CZ20012651A3/cs unknown
- 2000-02-23 CN CNA008041865A patent/CN1636053A/zh active Pending
2001
- 2001-08-23 NO NO20014091A patent/NO20014091L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE60002185T2 (de)	2003-12-18
KR20020000216A (ko)	2002-01-05
WO2000050568A3 (en)	2000-12-07
AU762763B2 (en)	2003-07-03
NO20014091D0 (no)	2001-08-23
EP1161521A2 (de)	2001-12-12
EP1161521B1 (de)	2003-04-16
PL350297A1 (en)	2002-12-02
PT1161521E (pt)	2003-08-29
GB9904281D0 (en)	1999-04-21
CN1636053A (zh)	2005-07-06
AU2682100A (en)	2000-09-14
RU2216336C2 (ru)	2003-11-20
DE60002185D1 (de)	2003-05-22
NO20014091L (no)	2001-08-23
ES2193938T3 (es)	2003-11-16
HUP0105168A3 (en)	2003-12-29
JP2002537406A (ja)	2002-11-05
ATE237680T1 (de)	2003-05-15
HUP0105168A2 (hu)	2002-05-29
HK1041284A1 (en)	2002-07-05
CA2361401A1 (en)	2000-08-31
WO2000050568A2 (en)	2000-08-31
HK1041284B (en)	2003-10-03
DK1161521T3 (da)	2003-06-16
CZ20012651A3 (cs)	2002-01-16
JP4716575B2 (ja)	2011-07-06

Publication	Publication Date	Title
SK11232001A3 (sk)	2002-01-07	Použitie hematopoietickej kmeňovej bunky
Kordower et al.	1997	Grafts of EGF‐responsive neural stem cells derived from GFAP‐hNGF transgenic mice: Trophic and tropic effects in a rodent model of Huntington's disease
Olson et al.	1991	Intraputaminal infusion of nerve growth factor to support adrenal medullary autografts in Parkinson's disease: one-year follow-up of first clinical trial
Kliot et al.	1990	Astrocyte-polymer implants promote regeneration of dorsal root fibers into the adult mammalian spinal cord
Joosten et al.	1995	Collagen implants and cortico‐spinal axonal growth after mid‐thoracic spinal cord lesion in the adult rat
Dunnett	1991	Cholinergic grafts, memory and ageing
Dunnett et al.	1989	Nigrostriatal reconstruction after 6-OHDA lesions in rats: combination of dopamine-rich nigral grafts and nigrostriatal “bridge” grafts
Ford-Holevinski et al.	1986	Laminin supports neurite outgrowth from explants of axotomized adult rat retinal neurons
JPH08502172A (ja)	1996-03-12	神経幹細胞を用いるミエリン再形成
DE69635924T2 (de)	2006-12-14	Isolierung und züchtung von schwannzellen
DE69628566T2 (de)	2004-05-06	Neurale transplantation durch verwendung von pluripotenten neuroepithelzellen
US6569421B2 (en)	2003-05-27	Treatment of brain damage
KR20090055691A (ko)	2009-06-03	인간 제대혈 유래 간엽 줄기세포를 유효성분으로 포함하는,신경전구세포 또는 신경줄기세포의 신경세포로의 분화 및증식 유도용 조성물
MXPA01010131A (es)	2002-08-20	Metodos de tratamiento de esquizofrenia.
Harvey et al.	1992	Survival and migration of transplanted male glia in adult female mouse brains monitored by a Y-chromosome-specific probe
Patkar et al.	2012	Conditionally immortalised neural stem cells promote functional recovery and brain plasticity after transient focal cerebral ischaemia in mice
Kalderon	1988	Differentiating astroglia in nervous tissue histogenesis/regeneration: studies in a model system of regenerating peripheral nerve
Kato et al.	2015	Successful transplantation of motoneurons into the peripheral nerve depends on the number of transplanted cells
KR20080049917A (ko)	2008-06-05	인간 제대혈 유래 간엽 줄기세포를 유효성분으로 포함하는,신경전구세포 또는 신경줄기세포의 신경세포로의 분화 및증식 유도용 조성물
Markham et al.	1994	Transplantation of fetal mesencephalic tissue in Parkinson's patients.
Crutcher	1990	The regulation of axonal growth in the mature mammalian nervous system
Nash	2002	Regeneration of the Adult Rat Spinal Cord in Response to Ensheathing Cells and Methylprednisolone
Stein	1988	Practical and theoretical issues in the uses of fetal brain tissue transplants to promote recovery from brain injury
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DONALD	2012	Uses of Fetal Brain Tissue Transplants to Promote Recovery from Brain Injury