SK1252003A3 - Composition for aqueous stabilization of fat-soluble vitamins - Google Patents

Composition for aqueous stabilization of fat-soluble vitamins Download PDF

Info

Publication number: SK1252003A3
Authority: SK; Slovakia
Prior art keywords: composition; fat; soluble vitamins; vitamins; water
Prior art date: 2000-07-04

Application number

SK125-2003A

Other languages

English (en)

Slovak (sk)

Inventor

Andras Bertha

Original Assignee

Andras Bertha

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-07-04

Filing date

2001-07-02

Publication date

2003-06-03

2001-07-02 Application filed by Andras Bertha filed Critical Andras Bertha

2003-06-03 Publication of SK1252003A3 publication Critical patent/SK1252003A3/sk

Links

229940088594 vitamin Drugs 0.000 title claims abstract description 88
229930003231 vitamin Natural products 0.000 title claims abstract description 88
235000013343 vitamin Nutrition 0.000 title claims abstract description 88
239000011782 vitamin Substances 0.000 title claims abstract description 88
239000000203 mixture Substances 0.000 title claims abstract description 73
230000006641 stabilisation Effects 0.000 title claims abstract description 15
238000011105 stabilization Methods 0.000 title claims abstract description 15
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 10
125000004432 carbon atom Chemical group C* 0.000 claims abstract description 10
150000001408 amides Chemical class 0.000 claims abstract description 6
150000001412 amines Chemical class 0.000 claims abstract description 5
238000002360 preparation method Methods 0.000 claims abstract description 4
239000012736 aqueous medium Substances 0.000 claims abstract 2
150000001735 carboxylic acids Chemical class 0.000 claims description 6
POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 claims description 5
239000005639 Lauric acid Substances 0.000 claims description 3
235000021355 Stearic acid Nutrition 0.000 claims description 3
QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 3
OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims description 3
OEIJHBUUFURJLI-UHFFFAOYSA-N octane-1,8-diol Chemical compound OCCCCCCCCO OEIJHBUUFURJLI-UHFFFAOYSA-N 0.000 claims description 3
239000000825 pharmaceutical preparation Substances 0.000 claims description 3
GGHDAUPFEBTORZ-UHFFFAOYSA-N propane-1,1-diamine Chemical compound CCC(N)N GGHDAUPFEBTORZ-UHFFFAOYSA-N 0.000 claims description 3
230000000087 stabilizing effect Effects 0.000 claims description 3
239000008117 stearic acid Substances 0.000 claims description 3
239000000654 additive Substances 0.000 claims description 2
239000008365 aqueous carrier Substances 0.000 claims 1
150000004985 diamines Chemical class 0.000 claims 1
239000002609 medium Substances 0.000 claims 1
150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
241001465754 Metazoa Species 0.000 description 43
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 39
241000283690 Bos taurus Species 0.000 description 12
239000003651 drinking water Substances 0.000 description 12
235000020188 drinking water Nutrition 0.000 description 12
238000000034 method Methods 0.000 description 12
239000012141 concentrate Substances 0.000 description 11
238000010790 dilution Methods 0.000 description 11
239000012895 dilution Substances 0.000 description 11
239000000839 emulsion Substances 0.000 description 10
235000013336 milk Nutrition 0.000 description 9
239000008267 milk Substances 0.000 description 9
210000004080 milk Anatomy 0.000 description 9
150000003721 vitamin K derivatives Chemical class 0.000 description 9
230000035622 drinking Effects 0.000 description 8
235000013601 eggs Nutrition 0.000 description 8
150000003722 vitamin derivatives Chemical class 0.000 description 8
238000009395 breeding Methods 0.000 description 7
230000001488 breeding effect Effects 0.000 description 7
238000002474 experimental method Methods 0.000 description 7
238000004519 manufacturing process Methods 0.000 description 7
239000012071 phase Substances 0.000 description 7
239000000126 substance Substances 0.000 description 7
229930003270 Vitamin B Natural products 0.000 description 6
239000007788 liquid Substances 0.000 description 6
239000003921 oil Substances 0.000 description 6
235000019198 oils Nutrition 0.000 description 6
239000012074 organic phase Substances 0.000 description 6
235000019156 vitamin B Nutrition 0.000 description 6
239000011720 vitamin B Substances 0.000 description 6
241000272517 Anseriformes Species 0.000 description 5
239000013543 active substance Substances 0.000 description 5
239000008194 pharmaceutical composition Substances 0.000 description 5
239000004094 surface-active agent Substances 0.000 description 5
238000012360 testing method Methods 0.000 description 5
YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 4
GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 4
CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 4
PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 4
229930003448 Vitamin K Natural products 0.000 description 4
150000001298 alcohols Chemical class 0.000 description 4
239000008346 aqueous phase Substances 0.000 description 4
150000001875 compounds Chemical class 0.000 description 4
238000005516 engineering process Methods 0.000 description 4
239000003925 fat Substances 0.000 description 4
SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 4
239000011550 stock solution Substances 0.000 description 4
235000019168 vitamin K Nutrition 0.000 description 4
239000011712 vitamin K Substances 0.000 description 4
229940046010 vitamin k Drugs 0.000 description 4
241000287828 Gallus gallus Species 0.000 description 3
BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 3
240000008042 Zea mays Species 0.000 description 3
235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 3
235000002017 Zea mays subsp mays Nutrition 0.000 description 3
OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 description 3
230000008901 benefit Effects 0.000 description 3
TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 description 3
235000013734 beta-carotene Nutrition 0.000 description 3
239000011648 beta-carotene Substances 0.000 description 3
229960002747 betacarotene Drugs 0.000 description 3
244000309466 calf Species 0.000 description 3
235000013330 chicken meat Nutrition 0.000 description 3
235000005822 corn Nutrition 0.000 description 3
239000003814 drug Substances 0.000 description 3
239000003995 emulsifying agent Substances 0.000 description 3
238000009472 formulation Methods 0.000 description 3
244000309465 heifer Species 0.000 description 3
238000005342 ion exchange Methods 0.000 description 3
238000011160 research Methods 0.000 description 3
239000011669 selenium Substances 0.000 description 3
229910052711 selenium Inorganic materials 0.000 description 3
239000004460 silage Substances 0.000 description 3
238000003860 storage Methods 0.000 description 3
OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 3
DCTMXCOHGKSXIZ-UHFFFAOYSA-N (R)-1,3-Octanediol Chemical compound CCCCCC(O)CCO DCTMXCOHGKSXIZ-UHFFFAOYSA-N 0.000 description 2
PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 description 2
FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 2
239000001763 2-hydroxyethyl(trimethyl)azanium Substances 0.000 description 2
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
235000019743 Choline chloride Nutrition 0.000 description 2
ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 2
241001076195 Lampsilis ovata Species 0.000 description 2
MYGVPKMVGSXPCQ-JEDNCBNOSA-N Methylmethionine sulfonium salt Chemical compound [Cl-].C[S+](C)CC[C@H](N)C(O)=O MYGVPKMVGSXPCQ-JEDNCBNOSA-N 0.000 description 2
241000286209 Phasianidae Species 0.000 description 2
FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 2
229930003268 Vitamin C Natural products 0.000 description 2
229930003427 Vitamin E Natural products 0.000 description 2
239000004480 active ingredient Substances 0.000 description 2
239000008186 active pharmaceutical agent Substances 0.000 description 2
FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
150000001413 amino acids Chemical class 0.000 description 2
229960002685 biotin Drugs 0.000 description 2
235000020958 biotin Nutrition 0.000 description 2
239000011616 biotin Substances 0.000 description 2
229960004203 carnitine Drugs 0.000 description 2
239000003795 chemical substances by application Substances 0.000 description 2
SGMZJAMFUVOLNK-UHFFFAOYSA-M choline chloride Chemical compound [Cl-].C[N+](C)(C)CCO SGMZJAMFUVOLNK-UHFFFAOYSA-M 0.000 description 2
229960003178 choline chloride Drugs 0.000 description 2
229940088679 drug related substance Drugs 0.000 description 2
210000002219 extraembryonic membrane Anatomy 0.000 description 2
OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 2
230000003862 health status Effects 0.000 description 2
230000014759 maintenance of location Effects 0.000 description 2
235000013372 meat Nutrition 0.000 description 2
238000002156 mixing Methods 0.000 description 2
229960003512 nicotinic acid Drugs 0.000 description 2
235000001968 nicotinic acid Nutrition 0.000 description 2
239000011664 nicotinic acid Substances 0.000 description 2
229940014662 pantothenate Drugs 0.000 description 2
239000011713 pantothenic acid Substances 0.000 description 2
230000000737 periodic effect Effects 0.000 description 2
238000003307 slaughter Methods 0.000 description 2
239000000243 solution Substances 0.000 description 2
210000001082 somatic cell Anatomy 0.000 description 2
235000015112 vegetable and seed oil Nutrition 0.000 description 2
239000008158 vegetable oil Substances 0.000 description 2
235000019155 vitamin A Nutrition 0.000 description 2
239000011719 vitamin A Substances 0.000 description 2
235000019154 vitamin C Nutrition 0.000 description 2
239000011718 vitamin C Substances 0.000 description 2
QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 description 2
235000019165 vitamin E Nutrition 0.000 description 2
229940046009 vitamin E Drugs 0.000 description 2
239000011709 vitamin E Substances 0.000 description 2
229940045997 vitamin a Drugs 0.000 description 2
241000272814 Anser sp. Species 0.000 description 1
241000282412 Homo Species 0.000 description 1
206010061218 Inflammation Diseases 0.000 description 1
OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
239000002253 acid Substances 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
230000002411 adverse Effects 0.000 description 1
239000003242 anti bacterial agent Substances 0.000 description 1
229940088710 antibiotic agent Drugs 0.000 description 1
125000003118 aryl group Chemical group 0.000 description 1
235000013361 beverage Nutrition 0.000 description 1
230000000740 bleeding effect Effects 0.000 description 1
210000000481 breast Anatomy 0.000 description 1
238000004364 calculation method Methods 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
239000000356 contaminant Substances 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
125000004122 cyclic group Chemical group 0.000 description 1
235000013365 dairy product Nutrition 0.000 description 1
235000005911 diet Nutrition 0.000 description 1
230000037213 diet Effects 0.000 description 1
239000006185 dispersion Substances 0.000 description 1
239000012153 distilled water Substances 0.000 description 1
229940079593 drug Drugs 0.000 description 1
238000011156 evaluation Methods 0.000 description 1
235000013861 fat-free Nutrition 0.000 description 1
239000000796 flavoring agent Substances 0.000 description 1
235000019634 flavors Nutrition 0.000 description 1
229960000304 folic acid Drugs 0.000 description 1
235000019152 folic acid Nutrition 0.000 description 1
239000011724 folic acid Substances 0.000 description 1
229940083565 folic acid 0.8 mg Drugs 0.000 description 1
230000035876 healing Effects 0.000 description 1
230000036541 health Effects 0.000 description 1
235000004280 healthy diet Nutrition 0.000 description 1
244000144980 herd Species 0.000 description 1
125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
230000004054 inflammatory process Effects 0.000 description 1
238000001802 infusion Methods 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
229910052500 inorganic mineral Inorganic materials 0.000 description 1
CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 1
230000009027 insemination Effects 0.000 description 1
230000000968 intestinal effect Effects 0.000 description 1
238000011835 investigation Methods 0.000 description 1
239000007791 liquid phase Substances 0.000 description 1
230000007774 longterm Effects 0.000 description 1
208000004396 mastitis Diseases 0.000 description 1
239000000463 material Substances 0.000 description 1
210000004379 membrane Anatomy 0.000 description 1
239000012528 membrane Substances 0.000 description 1
239000004530 micro-emulsion Substances 0.000 description 1
239000011707 mineral Substances 0.000 description 1
238000012986 modification Methods 0.000 description 1
230000004048 modification Effects 0.000 description 1
SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 description 1
230000003287 optical effect Effects 0.000 description 1
229940127557 pharmaceutical product Drugs 0.000 description 1
244000144977 poultry Species 0.000 description 1
238000009374 poultry farming Methods 0.000 description 1
235000013594 poultry meat Nutrition 0.000 description 1
230000008569 process Effects 0.000 description 1
238000012545 processing Methods 0.000 description 1
230000002207 retinal effect Effects 0.000 description 1
239000013049 sediment Substances 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
238000003756 stirring Methods 0.000 description 1
150000005846 sugar alcohols Polymers 0.000 description 1
230000007704 transition Effects 0.000 description 1
238000002255 vaccination Methods 0.000 description 1
238000005303 weighing Methods 0.000 description 1
230000004584 weight gain Effects 0.000 description 1
235000019786 weight gain Nutrition 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Fodder In General (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

SK125-2003A 2000-07-04 2001-07-02 Composition for aqueous stabilization of fat-soluble vitamins SK1252003A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU0002561A HU226322B1 (hu)	2000-07-04	2000-07-04	Adalékkompozíció zsírban oldódó vitaminok vizes stabilizálására, az így elõállított készítmények, valamint azok alkalmazhatósága különbözõ területeken
PCT/HU2001/000073 WO2002002145A2 (en)	2000-07-04	2001-07-02	Composition for aqueous stabilization of fat-soluble vitamins

Publications (1)

Publication Number	Publication Date
SK1252003A3 true SK1252003A3 (en)	2003-06-03

Family

ID=89978448

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK125-2003A SK1252003A3 (en)	2000-07-04	2001-07-02	Composition for aqueous stabilization of fat-soluble vitamins

Country Status (14)

Country	Link
US (1)	US20030229056A1 (cs)
EP (1)	EP1299124B1 (cs)
AT (1)	ATE461711T1 (cs)
AU (2)	AU2002216750B2 (cs)
CA (1)	CA2420130C (cs)
CZ (1)	CZ2003207A3 (cs)
DE (1)	DE60141632D1 (cs)
EA (1)	EA006547B1 (cs)
HR (1)	HRP20030119A2 (cs)
HU (1)	HU226322B1 (cs)
RO (1)	RO122581B1 (cs)
SK (1)	SK1252003A3 (cs)
WO (1)	WO2002002145A2 (cs)
YU (1)	YU8103A (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE102007012644A1 (de) *	2007-03-16	2008-09-18	Bayer Healthcare Ag	Stabilisierung von Vitamin B12
CN107683974B (zh) *	2017-09-01	2021-05-28	武汉轻工大学	一种促进雏鸡生长的保健型浓缩饮料及其制备方法
CN114370564B (zh) *	2020-10-15	2023-10-27	中国移动通信集团浙江有限公司	便于检修的通讯基站系统

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH388536A (fr) *	1960-03-31	1965-02-28	Andre Pottier Pierre	Procédé de protection des lipides contre l'oxydation
NL125301C (cs) *	1962-04-06
FR3517M (fr) *	1962-12-07	1965-09-06	Hoffmann La Roche	Médicament a base de compositions vitaminées.
CH433944A (de) *	1962-12-17	1967-04-15	Hoffmann La Roche	Präparat zur Vitaminierung von Lebens- und Futtermitteln und Verfahren zu dessen Herstellung
US6165500A (en) *	1990-08-24	2000-12-26	Idea Ag	Preparation for the application of agents in mini-droplets
US5478816A (en) *	1993-07-02	1995-12-26	Bristol-Myers Squibb Company	Liquid vitamin formulations containing vitamin D esters
US6162419A (en) *	1996-11-26	2000-12-19	Nicholas V. Perricone	Stabilized ascorbyl compositions
HU222559B1 (hu) *	1999-05-14	2003-08-28	András Bertha	Adalékkompozíció víztartalmú üzemanyagok stabilizálására, az így stabilizált üzemanyagok és ezek felhasználása

2000
- 2000-07-04 HU HU0002561A patent/HU226322B1/hu not_active IP Right Cessation
2001
- 2001-07-02 DE DE60141632T patent/DE60141632D1/de not_active Expired - Lifetime
- 2001-07-02 EA EA200300114A patent/EA006547B1/ru not_active IP Right Cessation
- 2001-07-02 HR HR20030119A patent/HRP20030119A2/xx not_active Application Discontinuation
- 2001-07-02 AT AT01984093T patent/ATE461711T1/de not_active IP Right Cessation
- 2001-07-02 CA CA2420130A patent/CA2420130C/en not_active Expired - Fee Related
- 2001-07-02 WO PCT/HU2001/000073 patent/WO2002002145A2/en not_active Ceased
- 2001-07-02 US US10/312,893 patent/US20030229056A1/en not_active Abandoned
- 2001-07-02 RO ROA200300003A patent/RO122581B1/ro unknown
- 2001-07-02 AU AU2002216750A patent/AU2002216750B2/en not_active Ceased
- 2001-07-02 AU AU1675002A patent/AU1675002A/xx active Pending
- 2001-07-02 SK SK125-2003A patent/SK1252003A3/sk unknown
- 2001-07-02 EP EP01984093A patent/EP1299124B1/en not_active Expired - Lifetime
- 2001-07-02 YU YU8103A patent/YU8103A/sh unknown
- 2001-07-02 CZ CZ2003207A patent/CZ2003207A3/cs unknown

Also Published As

Publication number	Publication date
EA006547B1 (ru)	2006-02-24
EP1299124B1 (en)	2010-03-24
HU226322B1 (hu)	2008-08-28
HRP20030119A2 (en)	2004-04-30
ATE461711T1 (de)	2010-04-15
AU2002216750B2 (en)	2006-08-31
WO2002002145A2 (en)	2002-01-10
EA200300114A1 (ru)	2003-06-26
DE60141632D1 (de)	2010-05-06
WO2002002145A3 (en)	2002-06-20
EP1299124A2 (en)	2003-04-09
CA2420130A1 (en)	2002-01-10
HU0002561D0 (en)	2000-08-28
CZ2003207A3 (cs)	2003-05-14
CA2420130C (en)	2011-01-18
YU8103A (sh)	2006-05-25
HUP0002561A2 (hu)	2002-05-29
AU1675002A (en)	2002-01-14
RO122581B1 (ro)	2009-09-30
US20030229056A1 (en)	2003-12-11

Legal Events

Date	Code	Title	Description
2010-12-07	FB9A	Suspension of patent application procedure

Publication	Publication Date	Title
Hemken	1979	Factors that influence the iodine content of milk and meat: a review
KR100702540B1 (ko)	2007-04-04	수 분배 시스템을 통해 표적 동물에 수-불용성 약물을투여하기 위한 수의학적 제제
JP2009504699A (ja)	2009-02-05	動物の雄の生殖能力を改善するための２５−ヒドロキシビタミンｄ３の使用
RU2259832C2 (ru)	2005-09-10	Препарат для усиления обменных процессов и иммунитета у сельскохозяйственных животных и птицы
Ramteke et al.	2014	Veterinary pharmaceutical dosage forms: A technical note
SK1252003A3 (en)	2003-06-03	Composition for aqueous stabilization of fat-soluble vitamins
CN101982176A (zh)	2011-03-02	兽用复方亚硒酸钠-维生素e口服纳米乳制剂与制备方法
JP2007507226A (ja)	2007-03-29	ラクトパミンの液状製剤
RU2044493C1 (ru)	1995-09-27	Способ кормления молодняка крупного рогатого скота
AU2002216750A1 (en)	2002-04-11	Composition for aqueous stabilization of fat-soluble vitamins
SU1676572A1 (ru)	1991-09-15	Витаминный кормовой аппарат "Диспервит Е" дл птиц
Rogers	1999	Iodine Supplementation of Cattle.
RU2845676C1 (ru)	2025-08-25	Способ повышения мясной продуктивности цыплят-бройлеров
RU2847663C1 (ru)	2025-10-15	Способ повышения мясной продуктивности цыплят-бройлеров
RU2845673C1 (ru)	2025-08-25	Способ повышения мясной продуктивности цыплят-бройлеров
RU2834470C1 (ru)	2025-02-11	Способ повышения количественных и качественных показателей ооцит-кумулюсных комплексов у коров-доноров при помощи фитодобавки Origanum vulgare
RU2818124C1 (ru)	2024-04-24	Способ экспериментального моделирования гипотиреоза у лабораторных крыс
RU2381693C1 (ru)	2010-02-20	Кормовая добавка
US8486949B2 (en)	2013-07-16	Use of azaperone for improving growth performance
US6525095B1 (en)	2003-02-25	Propionate feed supplement
McDonnell et al.	2002	The pharmacist and veterinary pharmaceutical dosage forms
Yeary	1966	Medicated Feed Additives: A Handbook on the Safe Use of Feed Additives and Drugs for Livestock and Poultry
TREATMENT–WORMS	0	TREATMENT–WORMS, LICE, MITES, PARASITES
JPH02131420A (ja)	1990-05-21	体重増量剤及びその製造方法と使用方法
NZ280059A (en)	1998-04-27	Animal treatment; comprises administering to an animal via the animals drinking water an oxidising agent; treatment composition containing oxidising agent