SK142696A3 - Amino acids derivative, method for preparation thereof, pharmaceutical compositions containing said compounds (ii) and their use - Google Patents

Amino acids derivative, method for preparation thereof, pharmaceutical compositions containing said compounds (ii) and their use Download PDF

Info

Publication number: SK142696A3
Authority: SK; Slovakia
Prior art keywords: phenyl; alkyl; group; acid; pro
Prior art date: 1994-05-07

Application number

SK1426-96A

Other languages

English (en)

Slovak (sk)

Inventor

Gerd Schnorrenberg

Franz Esser

Horst Dollinger

Birgit Jung

Georg Speck

Erich Buerger

Original Assignee

Boehringer Ingelheim Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-05-07

Filing date

1995-05-04

Publication date

1997-06-04

1994-12-22 Priority claimed from DE4445939A external-priority patent/DE4445939A1/de

1995-05-04 Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg

1997-06-04 Publication of SK142696A3 publication Critical patent/SK142696A3/sk

Links

0 CC(CC1C23C(N(C[C@](*)C4)C4C(*C(Cc4ncc[s]4)C(*(Cc4ccccc4C)=C)=O)=O)=O)(C4)C12C4(C)C3=O Chemical compound CC(CC1C23C(N(C[C@](*)C4)C4C(*C(Cc4ncc[s]4)C(*(Cc4ccccc4C)=C)=O)=O)=O)(C4)C12C4(C)C3=O 0.000 description 1
ANCGHLMCQLGOBG-IJSIVIDSSA-N CC(CCc1ccccc1C)C(C(Cc1c[nH]c2ccccc12)N(C)C(C([C@H](C)O)NC(C(C1C2(C)C3(C)CC2(C)C1)C3=O)=O)=O)=O Chemical compound CC(CCc1ccccc1C)C(C(Cc1c[nH]c2ccccc12)N(C)C(C([C@H](C)O)NC(C(C1C2(C)C3(C)CC2(C)C1)C3=O)=O)=O)=O ANCGHLMCQLGOBG-IJSIVIDSSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Ophthalmology & Optometry (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

SK1426-96A 1994-05-07 1995-05-04 Amino acids derivative, method for preparation thereof, pharmaceutical compositions containing said compounds (ii) and their use SK142696A3 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE4416255		1994-05-07
DE4445939A DE4445939A1 (de)	1994-05-07	1994-12-22	Neue Aminosäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen (II)
PCT/EP1995/001691 WO1995030687A1 (fr)	1994-05-07	1995-05-04	Antagonistes de la neurokinine (tachykinine)

Publications (1)

Publication Number	Publication Date
SK142696A3 true SK142696A3 (en)	1997-06-04

Family

ID=25936418

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1426-96A SK142696A3 (en)	1994-05-07	1995-05-04	Amino acids derivative, method for preparation thereof, pharmaceutical compositions containing said compounds (ii) and their use

Country Status (20)

Country	Link
US (2)	US5712273A (fr)
EP (1)	EP0804463A1 (fr)
JP (1)	JPH09512806A (fr)
CN (1)	CN1147260A (fr)
AU (1)	AU690275B2 (fr)
BG (1)	BG100946A (fr)
CA (1)	CA2189764A1 (fr)
CZ (1)	CZ325496A3 (fr)
EE (1)	EE9600186A (fr)
FI (1)	FI964473A7 (fr)
HR (1)	HRP950276A2 (fr)
HU (1)	HUT75708A (fr)
IL (1)	IL113625A0 (fr)
MX (1)	MX9605128A (fr)
NO (1)	NO964700L (fr)
NZ (1)	NZ285750A (fr)
PL (1)	PL317127A1 (fr)
RO (1)	RO115355B1 (fr)
SK (1)	SK142696A3 (fr)
WO (1)	WO1995030687A1 (fr)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
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DK0610487T3 (da) *	1992-09-03	2000-05-15	Boehringer Ingelheim Pharma	Nye aminosyrederivater, fremgangsmåde til deres fremstilling og farmaceutiske præparater indeholdende disse forbindelser
DE19541283A1 (de)	1995-11-06	1997-05-07	Boehringer Ingelheim Kg	Neue Aminosäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
DE19623950A1 (de) *	1996-06-15	1997-12-18	Boehringer Ingelheim Kg	Pharmazeutische Zubereitung in Form von Liposomen
US6329342B1 (en)	1997-08-19	2001-12-11	Eli Lilly And Company	Treatment of congestive heart failure with growth hormone secretagogues
US6639076B1 (en)	1998-08-18	2003-10-28	Eli Lilly And Company	Growth hormone secretagogues
GB9819860D0 (en)	1998-09-12	1998-11-04	Zeneca Ltd	Chemical compounds
JP2002542151A (ja)	1999-02-18	2002-12-10	科研製薬株式会社	成長ホルモン分泌促進物質としての新規なアミド誘導体
US6828331B1 (en) *	1999-02-19	2004-12-07	Eli Lilly And Company	Growth hormone secretagogues
MXPA02004330A (es)	1999-11-03	2004-07-30	Albany Molecular Res Inc	Tetrahidroisoquinolinas aril-y heteroaril-sustituidas y uso de las mismas para bloquear la recaptacion de norepinefrina, dopamina y serotonina..
US7163949B1 (en)	1999-11-03	2007-01-16	Amr Technology, Inc.	4-phenyl substituted tetrahydroisoquinolines and use thereof
AU784646B2 (en)	1999-11-18	2006-05-18	Antexpharma, Inc.	Substituted 1-benzazepines and derivatives thereof
KR100821410B1 (ko)	2000-07-11	2008-04-10	에이엠알 테크놀로지, 인크.	4-페닐 치환된 테트라하이드로이소퀴놀린 및 이의치료학적 용도
US7125840B2 (en) *	2001-10-09	2006-10-24	Eli Lilly And Company	Substituted dipeptides as growth hormone secretagogues
US20060167268A1 (en) *	2002-04-09	2006-07-27	Eli Lilly And Company, Patent Division,	Growth hormone secretagogues
US7396846B2 (en) *	2002-04-09	2008-07-08	Eli Lilly And Company	Growth hormone secretagogues
NZ552397A (en)	2004-07-15	2011-04-29	Amr Technology Inc	Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
US7238560B2 (en) *	2004-07-23	2007-07-03	Cree, Inc.	Methods of fabricating nitride-based transistors with a cap layer and a recessed gate
ES2382814T3 (es)	2005-05-17	2012-06-13	Merck Sharp & Dohme Ltd.	Ácido cis-4-[(4-clorofenil)sulfonil]-4-(2,5-difluorofenil)ciclohexanopropanoico para el tratamiento del cáncer
KR101594898B1 (ko)	2005-07-15	2016-02-18	알바니 몰레큘라 리써치, 인크.	아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
EP1940842B1 (fr)	2005-09-29	2012-05-30	Merck Sharp & Dohme Corp.	Dérivés acylés de spiropipéridine en tant que modulateurs du récepteur de la mélanocortine-4
GB0603041D0 (en)	2006-02-15	2006-03-29	Angeletti P Ist Richerche Bio	Therapeutic compounds
US8173629B2 (en)	2006-09-22	2012-05-08	Merck Sharp & Dohme Corp.	Method of treatment using fatty acid synthesis inhibitors
US20110218176A1 (en)	2006-11-01	2011-09-08	Barbara Brooke Jennings-Spring	Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
JP4611444B2 (ja)	2007-01-10	2011-01-12	イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー	ポリ（ａｄｐ−リボース）ポリメラーゼ（ｐａｒｐ）阻害剤としてのアミド置換インダゾール
JP5319518B2 (ja)	2007-04-02	2013-10-16	Ｍｓｄ株式会社	インドールジオン誘導体
AU2008269154B2 (en)	2007-06-27	2014-06-12	Merck Sharp & Dohme Llc	4-carboxybenzylamino derivatives as histone deacetylase inhibitors
AU2009222122A1 (en)	2008-03-03	2009-09-11	Tiger Pharmatech	Tyrosine kinase inhibitors
US9156812B2 (en)	2008-06-04	2015-10-13	Bristol-Myers Squibb Company	Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
WO2010114780A1 (fr)	2009-04-01	2010-10-07	Merck Sharp & Dohme Corp.	Inhibiteurs de l'activité akt
AU2010247735B2 (en)	2009-05-12	2015-07-16	Albany Molecular Research, Inc.	Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)- 1,2,3,4-tetrahydroisoquinoline and use thereof
WO2010132437A1 (fr)	2009-05-12	2010-11-18	Albany Molecular Research, Inc.	Aryle, hétéroaryle et tétrahydroisoquinolines à hétérocycle substitué et leur utilisation
AU2010247763B2 (en)	2009-05-12	2015-12-24	Albany Molecular Research, Inc.	7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
PE20121172A1 (es)	2009-10-14	2012-09-05	Merck Sharp & Dohme	Piperidinas sustituidas con actividad en la hdm2
WO2011163330A1 (fr)	2010-06-24	2011-12-29	Merck Sharp & Dohme Corp.	Nouveaux composés hétérocycliques utilisés comme inhibiteurs de erk
EP3330377A1 (fr)	2010-08-02	2018-06-06	Sirna Therapeutics, Inc.	Inhibition à médiation par interférence arn de caténine (protéine associée à cadhérine), expression du gène bêta 1 (ctnnb1) à l'aide de petit acide nucléique interférent (sian)
US9029341B2 (en)	2010-08-17	2015-05-12	Sirna Therapeutics, Inc.	RNA interference mediated inhibition of hepatitis B virus (HBV) gene expression using short interfering nucleic acid (siNA)
US8883801B2 (en)	2010-08-23	2014-11-11	Merck Sharp & Dohme Corp.	Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
EP2613782B1 (fr)	2010-09-01	2016-11-02	Merck Sharp & Dohme Corp.	Dérivés d'indazole utilisables en tant qu'inhibiteurs de la voie erk
US9242981B2 (en)	2010-09-16	2016-01-26	Merck Sharp & Dohme Corp.	Fused pyrazole derivatives as novel ERK inhibitors
WO2012058210A1 (fr)	2010-10-29	2012-05-03	Merck Sharp & Dohme Corp.	INHIBITION FACILITÉE PAR L'INTERFÉRENCE D'ARN DE L'EXPRESSION D'UN GÈNE AU MOYEN D'ACIDES NUCLÉIQUES INTERFÉRENTS COURTS (siNA)
WO2012087772A1 (fr)	2010-12-21	2012-06-28	Schering Corporation	Dérivés d'indazole utiles en tant qu'inhibiteurs de erk
AU2012245971A1 (en)	2011-04-21	2013-10-17	Piramal Enterprises Limited	A crystalline form of a salt of a morpholino sulfonyl indole derivative and a process for its preparation
EP2770987B1 (fr)	2011-10-27	2018-04-04	Merck Sharp & Dohme Corp.	Nouveaux composés qui sont des inhibiteurs d'erk
US20150299696A1 (en)	2012-05-02	2015-10-22	Sirna Therapeutics, Inc.	SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
RU2660429C2 (ru)	2012-09-28	2018-07-06	Мерк Шарп И Доум Корп.	Новые соединения, которые являются ингибиторами erk
RS56680B1 (sr)	2012-11-28	2018-03-30	Merck Sharp & Dohme	Kompozicije i postupci za lečenje kancera
KR102196882B1 (ko)	2012-12-20	2020-12-30	머크 샤프 앤드 돔 코포레이션	Hdm2 억제제로서의 치환된 이미다조피리딘
WO2014120748A1 (fr)	2013-01-30	2014-08-07	Merck Sharp & Dohme Corp.	Purines 2,6,7,8-substituées utilisées en tant qu'inhibiteurs de hdm2
WO2015034925A1 (fr)	2013-09-03	2015-03-12	Moderna Therapeutics, Inc.	Polynucléotides circulaires
IL287136B2 (en)	2016-02-05	2023-09-01	Denali Therapeutics Inc	Receptor inhibitors - interacting with protein kinase 1
EP3525785B1 (fr)	2016-10-12	2025-08-27	Merck Sharp & Dohme LLC	Inhibiteurs de kdm5
JP7208137B2 (ja)	2016-12-09	2023-01-18	デナリセラピューティクスインコーポレイテッド	化合物、組成物および方法
US10947234B2 (en)	2017-11-08	2021-03-16	Merck Sharp & Dohme Corp.	PRMT5 inhibitors
EP3706747B1 (fr)	2017-11-08	2025-09-03	Merck Sharp & Dohme LLC	Inhibiteurs de prmt5
US12173026B2 (en)	2018-08-07	2024-12-24	Merck Sharp & Dohme Llc	PRMT5 inhibitors
EP3833668B1 (fr)	2018-08-07	2025-03-19	Merck Sharp & Dohme LLC	Inhibiteurs de prmt5
US11981701B2 (en)	2018-08-07	2024-05-14	Merck Sharp & Dohme Llc	PRMT5 inhibitors
TW202334164A (zh)	2022-01-12	2023-09-01	美商戴納立製藥公司	（Ｓ）－５－苄基－Ｎ－（５－甲基－４－側氧基－２，３，４，５－四氫吡啶並［３，２－ｂ］［１，４］氧氮呯－３－基）－４Ｈ－１，２，４－三唑－３－甲醯胺的晶型

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8929070D0 (en) *	1989-12-22	1990-02-28	Fujisawa Pharmaceutical Co	Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
GB9023116D0 (en) *	1990-10-24	1990-12-05	Fujisawa Pharmaceutical Co	Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
DK0610487T3 (da) *	1992-09-03	2000-05-15	Boehringer Ingelheim Pharma	Nye aminosyrederivater, fremgangsmåde til deres fremstilling og farmaceutiske præparater indeholdende disse forbindelser

1995
- 1995-05-04 AU AU25249/95A patent/AU690275B2/en not_active Ceased
- 1995-05-04 JP JP7528677A patent/JPH09512806A/ja not_active Ceased
- 1995-05-04 CA CA002189764A patent/CA2189764A1/fr not_active Abandoned
- 1995-05-04 EE EE9600186A patent/EE9600186A/xx unknown
- 1995-05-04 CN CN95192859A patent/CN1147260A/zh active Pending
- 1995-05-04 EP EP95919392A patent/EP0804463A1/fr not_active Withdrawn
- 1995-05-04 PL PL95317127A patent/PL317127A1/xx unknown
- 1995-05-04 WO PCT/EP1995/001691 patent/WO1995030687A1/fr not_active Ceased
- 1995-05-04 RO RO96-02085A patent/RO115355B1/ro unknown
- 1995-05-04 US US08/434,613 patent/US5712273A/en not_active Expired - Fee Related
- 1995-05-04 NZ NZ285750A patent/NZ285750A/en unknown
- 1995-05-04 SK SK1426-96A patent/SK142696A3/sk unknown
- 1995-05-04 CZ CZ963254A patent/CZ325496A3/cs unknown
- 1995-05-04 MX MX9605128A patent/MX9605128A/es unknown
- 1995-05-04 FI FI964473A patent/FI964473A7/fi unknown
- 1995-05-04 HU HU9603082A patent/HUT75708A/hu unknown
- 1995-05-05 IL IL11362595A patent/IL113625A0/xx unknown
- 1995-05-05 HR HRP4445939.4A patent/HRP950276A2/hr not_active Application Discontinuation
- 1995-06-07 US US08/475,278 patent/US5700827A/en not_active Expired - Fee Related
1996
- 1996-10-29 BG BG100946A patent/BG100946A/xx unknown
- 1996-11-06 NO NO964700A patent/NO964700L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU2524995A (en)	1995-11-29
CZ325496A3 (en)	1997-09-17
HRP950276A2 (en)	1997-04-30
NZ285750A (en)	1998-08-26
FI964473A0 (fi)	1996-11-07
FI964473L (fi)	1996-11-07
HUT75708A (en)	1997-05-28
FI964473A7 (fi)	1996-11-07
BG100946A (bg)	1997-07-31
EE9600186A (et)	1997-08-15
CN1147260A (zh)	1997-04-09
NO964700D0 (no)	1996-11-06
CA2189764A1 (fr)	1995-11-16
PL317127A1 (en)	1997-03-17
IL113625A0 (en)	1995-08-31
JPH09512806A (ja)	1997-12-22
MX9605128A (es)	1997-08-30
AU690275B2 (en)	1998-04-23
NO964700L (no)	1996-11-06
HU9603082D0 (en)	1997-01-28
WO1995030687A1 (fr)	1995-11-16
US5700827A (en)	1997-12-23
US5712273A (en)	1998-01-27
RO115355B1 (ro)	2000-01-28
EP0804463A1 (fr)	1997-11-05

Publication	Publication Date	Title
SK142696A3 (en)	1997-06-04	Amino acids derivative, method for preparation thereof, pharmaceutical compositions containing said compounds (ii) and their use
US6232468B1 (en)	2001-05-15	Dipeptides with neurokinin-antagonistic activity
AU677792B2 (en)	1997-05-08	New aminoacid derivates, process for producing the same and pharmaceutical compositions containing these compounds
MXPA96005128A (en)	1997-08-01	New derivatives of amino acids, procedures for their preparation and pharmaceutical compositions that contain these compounds
WO1992017196A1 (fr)	1992-10-15	Peptides et pseudopeptides antithrombotiques
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