SK1452003A3 - Tartrate salts of thiazolidinedione derivative - Google Patents

Tartrate salts of thiazolidinedione derivative Download PDF

Info

Publication number: SK1452003A3
Authority: SK; Slovakia
Prior art keywords: mesotartrate; solvate; compound; pyridyl; heat
Prior art date: 2000-08-04

Application number

SK145-2003A

Other languages

English (en)

Slovak (sk)

Inventor

Andrew Simon Craig

Tim Chien Ting Ho

Michael Millan

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-04

Filing date

2001-08-03

Publication date

2004-05-04

2001-08-03 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2004-05-04 Publication of SK1452003A3 publication Critical patent/SK1452003A3/sk

Links

150000003892 tartrate salts Chemical class 0.000 title description 2
150000001467 thiazolidinediones Chemical class 0.000 title description 2
FEWJPZIEWOKRBE-XIXRPRMCSA-N Mesotartaric acid Chemical compound OC(=O)[C@@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-XIXRPRMCSA-N 0.000 claims abstract description 58
150000001875 compounds Chemical class 0.000 claims abstract description 38
239000012453 solvate Substances 0.000 claims abstract description 31
239000003814 drug Substances 0.000 claims abstract description 10
238000004519 manufacturing process Methods 0.000 claims abstract description 8
239000008194 pharmaceutical composition Substances 0.000 claims abstract description 6
ZOBPZXTWZATXDG-UHFFFAOYSA-N 1,3-thiazolidine-2,4-dione Chemical compound O=C1CSC(=O)N1 ZOBPZXTWZATXDG-UHFFFAOYSA-N 0.000 claims abstract description 3
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims abstract description 3
206010012601 diabetes mellitus Diseases 0.000 claims description 19
YASAKCUCGLMORW-UHFFFAOYSA-N Rosiglitazone Chemical compound C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O YASAKCUCGLMORW-UHFFFAOYSA-N 0.000 claims description 15
238000000034 method Methods 0.000 claims description 14
-1 mesotartrate ion Chemical class 0.000 claims description 12
150000003839 salts Chemical class 0.000 claims description 12
239000007787 solid Substances 0.000 claims description 12
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
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SK145-2003A 2000-08-04 2001-08-03 Tartrate salts of thiazolidinedione derivative SK1452003A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0019226.0A GB0019226D0 (en)	2000-08-04	2000-08-04	Novel pharmaceutical
PCT/GB2001/003514 WO2002012233A1 (fr)	2000-08-04	2001-08-03	Sels de tartrate de derive de thiazolidinedione

Publications (1)

Publication Number	Publication Date
SK1452003A3 true SK1452003A3 (en)	2004-05-04

Family

ID=9897028

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK145-2003A SK1452003A3 (en)	2000-08-04	2001-08-03	Tartrate salts of thiazolidinedione derivative

Country Status (23)

Country	Link
EP (1)	EP1307448A1 (fr)
JP (1)	JP2004505971A (fr)
KR (1)	KR20030022356A (fr)
CN (1)	CN1458930A (fr)
AP (1)	AP2003002737A0 (fr)
AU (1)	AU2001276508A1 (fr)
BG (1)	BG107605A (fr)
BR (1)	BR0112984A (fr)
CA (1)	CA2417828A1 (fr)
CZ (1)	CZ2003314A3 (fr)
EA (1)	EA200300231A1 (fr)
EC (1)	ECSP034468A (fr)
GB (1)	GB0019226D0 (fr)
HU (1)	HUP0300770A2 (fr)
IL (1)	IL154277A0 (fr)
MA (1)	MA25830A1 (fr)
MX (1)	MXPA03001086A (fr)
NO (1)	NO20030508L (fr)
OA (1)	OA12355A (fr)
PL (1)	PL360702A1 (fr)
SK (1)	SK1452003A3 (fr)
WO (1)	WO2002012233A1 (fr)
ZA (1)	ZA200300962B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
USRE39384E1 (en)	1993-09-01	2006-11-07	Smithkline Beecham P.L.C.	Substituted thiazolidinedione derivatives
FR2845602B1 (fr) *	2002-10-11	2005-07-08	Servier Lab	Association entre un ligand des recepteurs actives par les proliferateurs de peroxisomes et un agent antioxydant et les compositions pharmaceutiques qui les contiennent
US7264813B2 (en)	2003-09-24	2007-09-04	Nikken Sohonsha Corporation	Therapeutic uses of Dunaliella powder
CN102532122B (zh) *	2010-12-29	2015-12-02	开封制药(集团)有限公司	酒石酸罗格列酮的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9218830D0 (en) *	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds

2000
- 2000-08-04 GB GBGB0019226.0A patent/GB0019226D0/en not_active Ceased
2001
- 2001-08-03 OA OA1200300029A patent/OA12355A/en unknown
- 2001-08-03 IL IL15427701A patent/IL154277A0/xx unknown
- 2001-08-03 KR KR10-2003-7001605A patent/KR20030022356A/ko not_active Withdrawn
- 2001-08-03 WO PCT/GB2001/003514 patent/WO2002012233A1/fr not_active Ceased
- 2001-08-03 AP APAP/P/2003/002737A patent/AP2003002737A0/en unknown
- 2001-08-03 CA CA002417828A patent/CA2417828A1/fr not_active Abandoned
- 2001-08-03 CZ CZ2003314A patent/CZ2003314A3/cs unknown
- 2001-08-03 CN CN01815682A patent/CN1458930A/zh active Pending
- 2001-08-03 PL PL01360702A patent/PL360702A1/xx not_active Application Discontinuation
- 2001-08-03 EA EA200300231A patent/EA200300231A1/ru unknown
- 2001-08-03 HU HU0300770A patent/HUP0300770A2/hu unknown
- 2001-08-03 EP EP01954161A patent/EP1307448A1/fr not_active Withdrawn
- 2001-08-03 JP JP2002518208A patent/JP2004505971A/ja active Pending
- 2001-08-03 MX MXPA03001086A patent/MXPA03001086A/es unknown
- 2001-08-03 SK SK145-2003A patent/SK1452003A3/sk unknown
- 2001-08-03 AU AU2001276508A patent/AU2001276508A1/en not_active Abandoned
- 2001-08-03 BR BR0112984-8A patent/BR0112984A/pt not_active IP Right Cessation
2003
- 2003-01-31 NO NO20030508A patent/NO20030508L/no not_active Application Discontinuation
- 2003-02-03 MA MA27022A patent/MA25830A1/fr unknown
- 2003-02-04 EC EC2003004468A patent/ECSP034468A/es unknown
- 2003-02-04 ZA ZA200300962A patent/ZA200300962B/en unknown
- 2003-02-28 BG BG107605A patent/BG107605A/bg unknown

Also Published As

Publication number	Publication date
ECSP034468A (es)	2003-03-31
NO20030508D0 (no)	2003-01-31
IL154277A0 (en)	2003-09-17
NO20030508L (no)	2003-03-20
BG107605A (bg)	2003-09-30
MXPA03001086A (es)	2003-05-27
CN1458930A (zh)	2003-11-26
EP1307448A1 (fr)	2003-05-07
WO2002012233A1 (fr)	2002-02-14
GB0019226D0 (en)	2000-09-27
EA200300231A1 (ru)	2003-06-26
KR20030022356A (ko)	2003-03-15
JP2004505971A (ja)	2004-02-26
ZA200300962B (en)	2003-10-29
CZ2003314A3 (cs)	2004-02-18
BR0112984A (pt)	2003-06-10
OA12355A (en)	2004-03-19
CA2417828A1 (fr)	2002-02-14
MA25830A1 (fr)	2003-07-01
PL360702A1 (en)	2004-09-20
HUP0300770A2 (hu)	2003-11-28
AU2001276508A1 (en)	2002-02-18
AP2003002737A0 (en)	2003-03-31

Publication	Publication Date	Title
SK286399B6 (sk)	2008-09-05	V podstate nehydratovaná a nehygroskopická alebo iba mierne hygroskopická hydrochloridová soľ 5-[4-[2-(N-metyl-N-(2- pyridyl)amino)etoxy]benzyl]tiazolidín-2,4-diónu, spôsob jej prípravy, farmaceutický prostriedok s jej obsahom a jej použitie
SK1442003A3 (en)	2004-05-04	Tartrate salts of thiazolidinedione derivative
US20070185167A1 (en)	2007-08-09	Sodium salts of 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione
SK1462003A3 (en)	2004-06-08	Tartrate salt of thiazolidinedione derivative
SK2632003A3 (en)	2003-12-02	The hydrochloride salt of 5-[4-[2-(N-methyl-N-(2- pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione
CZ2003314A3 (cs)	2004-02-18	Derivát thiazolidindionu ve formě soli kyseliny vinné
SK1432003A3 (en)	2004-03-02	Tartrate salts of thiazolidinedione derivative
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US20040102485A1 (en)	2004-05-27	Tartrate salt of thiazolidinedione derivative
AU2001292028A1 (en)	2002-06-20	Sodium salts of 5-'4-'2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl] thiazolidine-2,4-dione
HK1057358B (en)	2008-05-30	Tartrate salt of thiazolidinedione derivative